Monochromatic pupillometry in unilateral glaucoma discloses no adaptive changes subserved by the ipRGCs

Frontiers in Neurology

Volumn 5 FEB, Issue , 2014, Pages

  Nissen, Claus ^a   Sander, Birgit ^a   Milea, Dan ^a,b   Kolko, Miriam ^a   Herbst, Kristina ^a   Hamard, Pascale ^c   Lund Andersen, Henrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^c CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

Author keywords

Intrinsically photosensitive retinal ganglion cells; Melanopsin; Pupillary light reflex; Unilateral glaucoma

Indexed keywords

ADULT; AGED; ANALYTICAL PARAMETERS; ARTICLE; AUTOMATION; BLUE LIGHT; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLAUCOMA; HUMAN; LIGHT EXPOSURE; MALE; MIDDLE AGED; MONOCHROMATIC PUPILLOMETRY; OPTICAL COHERENCE TOMOGRAPHY; PERIMETRY; PHOTOSENSITIVITY; PUPIL REFLEX; PUPILLOMETER; PUPILLOMETRY; RED LIGHT; RESPONSE TIME; RETINA GANGLION CELL; RETINAL NERVE FIBER LAYER THICKNESS;

EID: 84895528187     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2014.00015     Document Type: Article

References (12)

1. Gamlin PD, Mcdougal DH, Pokorny J, Smith VC, Yau KW, Dacey DM. Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Vision Res (2007) 47:946-54. doi: 10.1016/j.visres.2006.12.015.
2. Kawasaki A, Kardon RH. Intrinsically photosensitive retinal ganglion cells. J Neuroophthalmol (2007) 27:195-204. doi:10.1097/WNO.0b013e31814b1df9.
3. Kardon R, Anderson SC, Damarjian TG, Grace EM, Stone E, Kawasaki A. Chromatic pupil responses: preferential activation of the melanopsin-mediated versus outer photoreceptor-mediated pupil light reflex. Ophthalmology (2009) 116:1564-73. doi:10.1016/j.ophtha.2009.02.007.
4. Berson DM. Strange vision: ganglion cells as circadian photoreceptors. Trends Neurosci (2003) 26:314-20. doi:10.1016/S0166-2236(03)00130-9.
5. Hattar S, Liao HW, Takao M, Berson DM, Yau KW. Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science (2002) 295:1065-70. doi:10.1126/science.1069609.
6. McDougal DH, Gamlin PD. The influence of intrinsically-photosensitive retinal ganglion cells on the spectral sensitivity and response dynamics of the human pupillary light reflex. Vision Res (2010) 50:72-87. doi:10.1016/j.visres.2009.10.012.
7. Kankipati L, Girkin CA, Gamlin PD. The post-illumination pupil response is reduced in glaucoma patients. Invest Ophthalmol Vis Sci (2011) 52:2287-92. doi:10.1167/iovs.10-6023.
8. Feigl B, Mattes D, Thomas R, Zele AJ. Intrinsically photosensitive (melanopsin) retinal ganglion cell function in glaucoma. Invest Ophthalmol Vis Sci (2011) 52:4362-7. doi:10.1167/iovs.10-7069.
9. Herbst K, Sander B, Lund-Andersen H, Wegener M, Hannibal J, Milea D. Unilateral anterior ischemic optic neuropathy: chromatic pupillometry in affected, fellow non-affected and healthy control eyes. Front Neurol (2013) 4:52. doi:10.3389/fneur.2013.00052.
10. Herbst K, Sander B, Lund-Andersen H, Broendsted AE, Kessel L, Hansen MS, et al. Intrinsically photosensitive retinal ganglion cell function in relation to age: a pupillometric study in humans with special reference to the age-related optic properties of the lens. BMC Ophthalmol (2012) 12:4. doi:10.1186/1471-2415-12-4.
11. Herbst K, Sander B, Milea D, Lund-Andersen H, Kawasaki A. Test-retest repeatability of the pupil light response to blue and red light stimuli in normal human eyes using a novel pupillometer. Front Neurol (2011) 2:10. doi:10.3389/fneur.2011.00010.
12. Nissen C, Sander B, Lund-Andersen H. The effect of pupil size on stimulation of the melanopsin containing retinal ganglion cells, as evaluated by monochromatic pupillometry. Front Neurol (2011) 2:92. doi:10.3389/fneur.2011.00092.