Whole-blood global DNA methylation is increased in amyotrophic lateral sclerosis independently of age of onset

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Volumn 15, Issue 1-2, 2014, Pages 98-105

  Tremolizzo, Lucio ^a   Messina, Paolo ^b   Conti, Elisa ^a   Sala, Gessica ^a   Cecchi, Matteo ^c   Airoldi, Luisa ^c   Pastorelli, Roberta ^c   Pupillo, Elisabetta ^b   Bandettini Di Poggio, Monica ^d   Filosto, Massimiliano ^e   Lunetta, Christian ^f   Agliardi, Cristina ^g   Guerini, Franca ^g   Mandrioli, Jessica ^h   Calvo, Andrea ⁱ   Beghi, Ettore ^b   Ferrarese, Carlo ^a   Cotelli, M S ^j   Corbo, M ^j   Maestri, E ^j   Georgoulopoulou, E ^j   Marzorati, L ^j   Susani, E ^j   Arosio, A ^j   Chio A ^j   Fuda, G ^j   Pisa, F ^j   more..

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b Laboratory of Neurological Disorders   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

^e SPEDALI CIVILI   (Italy)

^f OSPEDALE NIGUARDA CA GRANDA   (Italy)

^g IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^h UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

ⁱ UNIVERSITY OF TURIN   (Italy)

^j NONE   (Italy)

more..

Author keywords

Age of onset; Amyotrophic lateral sclerosis; Blood; DNA methylation; Epigenetics; Homocysteine; Methionine; Peripheral marker

Indexed keywords

DNA; HOMOCYSTEINE; METHIONINE; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ADULT; AGED; AMINO ACID BLOOD LEVEL; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BLOOD; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ION MONITORING; ISOTOPE DILUTION ASSAY; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY SELECTED REACTION MONITORING MASS SPECTROMETRY; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; ONSET AGE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; WHOLE BLOOD GLOBAL DNA METHYLATION;

ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANALYSIS OF VARIANCE; CHROMATOGRAPHY, LIQUID; DEOXYCYTOSINE NUCLEOTIDES; DNA METHYLATION; FEMALE; HOMOCYSTEINE; HUMANS; MALE; METHIONINE; MIDDLE AGED; ROC CURVE; TRITIUM;

EID: 84895524855     PISSN: 21678421     EISSN: 21679223     Source Type: Journal    
DOI: 10.3109/21678421.2013.851247     Document Type: Article

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