The influence of test experience and NK1 receptor antagonists on the performance of NK1R-/- and wild type mice in the 5-Choice Serial Reaction-Time Task

Journal of Psychopharmacology

Volumn 28, Issue 3, 2014, Pages 270-281

  Weir, R K ^a   Dudley, J A ^a   Yan, T C ^a   Grabowska, E M ^a   Pena Oliver Y ^b   Ripley, T L ^a   Stephens, D N ^a   Stanford, S C ^a   Hunt, S P ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

5 Choice Serial Reaction Time Task; Attention deficit hyperactivity disorder; calcium channels; impulsivity; inattentiveness; locomotor hyperactivity; mouse study; NK1 receptor; NK1 receptor antagonist; perserveration; substance P receptor

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; NEUROKININ 1 RECEPTOR;

ABNORMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EXPERIENCE; GENOTYPE; LATENT PERIOD; MALE; MOUSE; NONHUMAN; PERSEVERATION; PRIORITY JOURNAL; RESPONSE TIME; STIMULUS RESPONSE;

5-CHOICE SERIAL REACTION-TIME TASK; ATTENTION DEFICIT HYPERACTIVITY DISORDER; CALCIUM CHANNELS; IMPULSIVITY; INATTENTIVENESS; LOCOMOTOR HYPERACTIVITY; MOUSE STUDY; NK1 RECEPTOR; NK1 RECEPTOR ANTAGONIST; PERSERVERATION; SUBSTANCE P RECEPTOR;

ANIMALS; BEHAVIOR, ANIMAL; CHOICE BEHAVIOR; MALE; MICE; MICE, KNOCKOUT; NEUROKININ-1 RECEPTOR ANTAGONISTS; REACTION TIME; RECEPTORS, NEUROKININ-1;

EID: 84895514646     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881113495722     Document Type: Article

References (53)

1. Adriani W, Caprioli A, Granstrem O, et al. The spontaneously hypertensive-rat as an animal model of ADHD: Evidence for impulsive and non-impulsive subpopulations. Neurosci Biobehav Rev. 2003 ; 27: 639-651
2. Agostino PV, Do Nascimento M, Bussi IL, et al. Circadian modulation of interval timing in mice. Brain Res. 2011 ; 1370: 154-163
3. Aston-Jones G, Cohen JD. Adaptive gain and the role of the locus coeruleus-norepinephrine system in optimal performance. J Comp Neurol. 2005 ; 493: 99-110
4. Beau J. Activity rhythms in mice III: Stability and plasticity of rhythm characteristics in experimental and environmental conditions. Physiol Behav. 1992 ; 52: 231-235
5. 2/3 receptors in the core and shell subregions of the nucleus accumbens. Neuropsychopharmacol. 2010 ; 35: 560-569
6. Castellanos FX, Marvasti FF, Ducharme JL, et al. Executive function oculomotor tasks in girls with ADHD. J Am Acad Child Adolesc Psychiatry. 2000 ; 39: 644-650
7. Chiang HL, Gau SS, Ni HC, et al. Association between symptoms and subtypes of attention-deficit hyperactivity disorder and sleep problems/disorders. J Sleep Res. 2010 ; 19: 535-545
8. Clark RA, Shoaib M, Hewitt KN, et al. A comparison of InVivoStat with other statistical software packages for analysis of data generated from animal experiments. J Psychopharmacol. 2011 ; 26: 1136-1142
9. Cole BJ, Robbins TW. Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-Choice Serial Reaction Time Task: New evidence for central dopaminergic-noradrenergic interactions. Psychopharmacol. 1987 ; 91: 458-466
10. Colwell CS. Linking neural activity and molecular oscillations in the SCN. Nat Rev Neurosci. 2011 ; 12: 553-569
11. Dalley JW, Roiser JP. Dopamine, serotonin and impulsivity. Neuroscience. 2012 ; 215: 42-58
12. Dalley JW, McGaughy J, O'Connell MT, et al. Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task. J Neurosci. 2001 ; 21: 4908-4914
13. De Felipe C, Herrero JF, O'Brien JA, et al. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature. 1998 ; 392: 394-397
14. Dudley JA, Weir RK, Yan TC, et al. Antagonism of L-type Cav channels with nifedipine differentially affects performance of wildtype and NK1R-/- mice in the 5-Choice Serial Reaction-Time Task. Neuropharmacol. 2013 ; 64: 329-336
15. Economidou D, Theobald DE, Robbins TW, et al. Norepinephrine and dopamine modulate impulsivity on the 5-Choice Serial Reaction Time Task through opponent actions in the shell and core sub-regions of the nucleus accumbens. Neuropsychopharmacol. 2012 ; 37: 2057-2066
16. Epstein JN, Langberg JM, Rosen PJ, et al. Evidence for higher reaction time variability for children with ADHD on a range of cognitive tasks including reward and event rate manipulations. Neuropsychology. 2011 ; 25: 427-441
17. Fisher AS, Stewart RJ, Yan T, et al. Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice. Eur J Neurosci. 2007 ; 25: 1195-1204
18. Froger N, Gardier AM, Moratalla R, et al. 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization. J Neurosci. 2001 ; 21: 8188-8197
19. Garret C, Carruette A, Fardin V, et al. Pharmacological properties of a potent and selective nonpeptide substance P antagonist. Proc Natl Acad Sci USA. 1991 ; 88: 10208-10212
20. Guard S, Boyle SJ, Tang KW, et al. The interaction of the NK1 receptor antagonist CP-96,345 with L-type calcium channels and its functional consequences. Br J Pharmacol. 1993 ; 110: 385-391
21. Heal DJ, Smith SL, Findling RL. ADHD: Current and future therapeutics. Curr Topics Behav Neurosci. 2012 ; 9: 361-390
22. Herpfer I, Hunt SP, Stanford SC. A comparison of neurokinin 1 receptor knock-out (NK1-/-) and wildtype mice: Exploratory behaviour and extracellular noradrenaline concentration in the cerebral cortex of anaesthetised subjects. Neuropharmacol. 2005 ; 48: 706-719
23. Humby T, Wilkinson L, Dawson G. Assaying aspects of attention and impulse control in mice using the 5-Choice Serial Reaction Time Task. Curr Protoc Neurosci. 2005 ;: 8.5H. 1-8.5H 15
24. Ko GY, Shi L, Ko ML. Circadian regulation of ion channels and their functions. J Neurochem. 2009 ; 110: 1150-1169
25. Ko ML, Shi L, Grushin K, et al. Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways. J Cell Biochem. 2012 ; 113: 911-922
26. Koffarnus MN, Katz JL. Response requirement and increases in accuracy produced by stimulant drugs in a 5-Choice Serial Reaction-Time Task in rats. Psychopharmacol. 2011 ; 213: 723-733
27. Kuntsi J, Klein C. Intraindividual variability in ADHD and its implications for research of causal links. Curr Top Behav Neurosci. 2012 ; 9: 67-91
28. Kuntsi J, Andreou P, Ma J, et al. Testing assumptions for endophenotype studies in ADHD: Reliability and validity of tasks in a general population sample. BMC Psychiatry. 2005 ; 5: 40
29. Maiolini M, Jr Mattia NF, Conceição IM, et al. Effects of single and long-term administration of nifedipine on dopamine-related behaviors. Braz J Med Biol Res. 1994 ; 27: 725-730
30. Murphy BJ, Rogers CA, Sunahara RK, et al. Identification, characterization, and photoaffinity labeling of the dihydropyridine receptor associated with the L-type calcium channel from bovine adrenal medulla. Mol Pharmacol. 1990 ; 37: 173-181
31. Nahm SS, Farnell YZ, Griffith W, et al. Circadian regulation and function of voltage-dependent calcium channels in the suprachiasmatic nucleus. J Neurosci. 2005 ; 25: 9304-9308
32. Oliver YP, Ripley TL, Stephens DN. Ethanol effects on impulsivity in two mouse strains: Similarities to diazepam and ketamine. Psychopharmacol. 2009 ; 204: 679-692
33. Patel S, Stolerman IP, Asherson P, et al. Attentional performance of C57BL/6 and DBA/2 mice in the 5-Choice Serial Reaction Time Task. Behav Brain Res. 2006 ; 170: 197-203
34. Piggins HD, Samuels RE, Coogan AN, et al. Distribution of substance P and neurokinin-1 receptor immunoreactivity in the suprachiasmatic nuclei and intergeniculate leaflet of hamster, mouse, and rat. J Comp Neurol. 2001 ; 438: 50-65
35. Pioli EY, Meissner W, Sohr R, et al. Differential behavioural effects of partial bilateral lesions of ventral tegmental area or substantia nigra pars compacta in rats. Neuroscience. 2008 ; 153: 1213-1224
36. Praamstra P, Kourtis D, Kwok HF, et al. Neurophysiology of implicit timing in serial choice reaction-time performance. J Neurosci. 2006 ; 26: 5448-5455
37. Prasad V, Brogan E, Mulvaney C, et al. How effective are drug treatments for children with ADHD at improving on-task behaviour and academic achievement in the school classroom? A systematic review and meta-analysis. Eur Child Adolesc Psychiatry. 2012 ; 22: 203-216
38. Rupniak NM, Boyce S, Williams AR, et al. Antinociceptive activity of NK1 receptor antagonists: Non-specific effects of racemic RP67580. Br J Pharmacol. 1993 ; 110: 1607-1613
39. Sanchez-Roige S, Peña-Oliver Y, Stephens DN. Measuring impulsivity in mice: The five-Choice Serial Reaction Time Task. Psychopharmacology. 2012 ; 219: 253-270
40. Seabrook GR, Shepheard SL, Williamson DJ, et al. L-733,060, a novel tachykinin NK1 receptor antagonist; effects in [Ca2+] imobilisation, cardiovascular and dural extravasation assays. Eur J Pharmacol. 1996 ; 317: 129-135
41. Smith A, Taylor E, Rogers JW, et al. Evidence for a pure time perception deficit in children with ADHD. J Child Psychol Psychiatry. 2002 ; 43: 529-542
42. Soreni N, Crosbie J, Ickowicz A, et al. Stop signal and Conners' continuous performance tasks: Test-retest reliability of two inhibition measures in ADHD children. J Atten Disord. 2009 ; 13: 137-143
43. Späti J, Münch M, Blatter K, et al. Impact of age, sleep pressure and circadian phase on time-of-day estimates. Behav Brain Res. 2009 ; 201: 48-52
44. Stanford SC. Central noradrenergic neurones and stress. Pharmacol Ther. 1995 ; 68: 297-242
45. Tang ZZ, Liao P, Li G, et al. Differential splicing patterns of L-type calcium channel Cav1.2 subunit in hearts of spontaneously hypertensive rats and Wistar Kyoto rats. Biochim Biophys Acta. 2008 ; 1783: 118-130
46. Walker SE, Peña-Oliver Y, Stephens DN. Learning not to be impulsive: Disruption by experience of alcohol withdrawal. Psychopharmacol. 2011 ; 217: 433-442
47. Weinert D, Waterhouse J. Diurnally-changing effects of locomotor activity on body temperature in laboratory mice. Physiol Behav. 1998 ; 63: 837-843
48. Winocur G, Hasher L. Age and time-of-day effects on learning and memory in a non-matching-to-sample test. Neurobiol Aging. 2004 ; 25: 1107-1115
49. Yan TC, Hunt SP, Stanford SC. Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: A model of attention deficit hyperactivity disorder. Neuropharmacol. 2009 ; 57: 627-635
50. Yan TC, Dudley JA, Weir RK, et al. Performance deficits of NK1 receptor knockout mice in the 5-Choice Serial Reaction-Time Task: Effects of d-amphetamine, stress and time of day. PLoS ONE. 2011 ; 6: e17586
51. Yan TC, McQuillin A, Thapar A, et al. NK1 (TACR1) receptor gene "knockout" mouse phenotype predicts genetic association with ADHD. J Psychopharmacol. 2010 ; 24: 27-38
52. Young JW, Van Enkhuizen J, Winstanle CA, et al. Increased risk-taking behaviour in dopamine transporter knockdown mice: Further support for a mouse model of mania. J Psychopharmacol. 2011 ; 25: 934-943
53. Zhang Q, Li JX, Zheng JW, et al. L-type Ca (2+) channel blockers inhibit the development but not the expression of sensitization to morphine in mice. Eur J Pharmacol. 2003 ; 467: 145-150