Genetic silencing of Nrf2 enhances X-ROS in dysferlin-deficient muscle

Frontiers in Physiology

Volumn 5 FEB, Issue , 2014, Pages

  Kombairaju, Ponvijay ^a   Kerr, Jaclyn P ^b   Roche, Joseph A ^b,d   Pratt, Stephen J P ^b   Lovering, Richard M ^b   Sussan, Thomas E ^a   Kim, Jung Hyun ^a   Shi, Guoli ^c   Biswal, Shyam ^a   Ward, Christopher W ^c  

^a Johns Hopkins University   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF NURSING   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

Dysferlin; Dystrophy; Nrf2; ROS; X ROS

Indexed keywords

DYSFERLIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; DYSFERLINOPATHY; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE SILENCING; HISTOPATHOLOGY; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NRF2 GENE; OXIDATION REDUCTION STATE; PROTEIN DEFICIENCY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

EID: 84895505670     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2014.00057     Document Type: Article

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