Ultrasound colour Doppler is associated with synovial pathology in biopsies from hand joints in rheumatoid arthritis patients: A cross-sectional study

Annals of the Rheumatic Diseases

Volumn 73, Issue 4, 2014, Pages 678-683

  Andersen, Martin ^a,b   Ellegaard, Karen ^a   Hebsgaard, Josephine B ^b   Christensen, Robin ^a   Torp Pedersen, Søren ^a   Kvist, Peter H ^b   Søe, Niels ^c   Rømer, John ^b   Vendel, Nina ^c   Bartels, Else Marie ^a   Danneskiold Samsøe, Bente ^a   Bliddal, Henning ^a  

^a Mental Health Center Glostrup   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD68 ANTIGEN; KI 67 ANTIGEN; VON WILLEBRAND FACTOR;

ADULT; ARTHROSCOPY; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; COLOR ULTRASOUND FLOWMETRY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HAND DISEASE; HAND JOINT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; JOINT BIOPSY; MALE; NEEDLE BIOPSY; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SYNOVITIS;

RHEUMATOID ARTHRITIS; SYNOVITIS; ULTRASONOGRAPHY;

ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS, RHEUMATOID; ARTHROSCOPY; BIOPSY, NEEDLE; CROSS-SECTIONAL STUDIES; FEMALE; HAND JOINTS; HUMANS; MALE; MICROCIRCULATION; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; SYNOVIAL MEMBRANE; SYNOVITIS; ULTRASONOGRAPHY, DOPPLER, COLOR;

EID: 84895488512     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2012-202669     Document Type: Article

References (25)

1. Haringman JJ, Gerlag DM, Zwinderman AH, et al. Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis. Ann Rheum Dis 2005;64:834-38. (Pubitemid 40733904)
2. van Baarsen LG, Wijbrandts CA, Timmer TC, et al. Synovial tissue heterogeneity in rheumatoid arthritis in relation to disease activity and biomarkers in peripheral blood. Arthritis Rheum 2010;62:1602-7.
3. Verschueren PC, Lories RJ, Daans M, et al. Detection, identification and in vivo treatment responsiveness of bone morphogenetic protein (BMP)-activated cell populations in the synovium of patients with rheumatoid arthritis. Ann Rheum Dis 2009;68:117-23.
4. van de Sande MG, Gerlag DM, Lodde BM, et al. Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials. Ann Rheum Dis 2011;70:423-7.
5. Wittoek R, Carron P, Verbruggen G. Structural and inflammatory sonographic findings in erosive and non-erosive osteoarthritis of the interphalangeal finger joints. Ann Rheum Dis 2010;69:2173-6.
6. Aletaha D, Neogi T, Silman AJ, etal. Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 2010;69:1580-8.
7. Brown AK, Quinn MA, Karim Z, et al. Presence of significant synovitis in rheumatoid arthritis patients with disease-modifying antirheumatic drug-induced clinical remission: evidence from an imaging study may explain structural progression. Arthritis Rheum 2006;54:3761-73. (Pubitemid 44955876)
8. Brown AK, Conaghan PG, Karim Z, et al. An explanation for the apparent dissociation between clinical remission and continued structural deterioration in rheumatoid arthritis. Arthritis Rheum 2008;58:2958-67.
9. Ellegaard K, Christensen R, Torp-Pedersen S, et al. Ultrasound Doppler measurements predict success of treatment with anti-TNF-α drug in patients with rheumatoid arthritis: a prospective cohort study. Rheumatology (Oxford) 2011;50:506-12.
10. Labanauskaite G, Sarauskas V. Correlation of power Doppler sonography with vascularity of the synovial tissue. Medicina (Kaunas.) 2003;39:480-3.
11. Schmidt WA, Volker L, Zacher J, et al. Colour Doppler ultrasonography to detect pannus in knee joint synovitis. Clin Exp Rheumatol 2000;18:439-44. (Pubitemid 30616938)
12. Walther M, Harms H, Krenn V, et al. Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum 2001;44:331-8. (Pubitemid 32207026)
13. Koski JM, Saarakkala S, Helle M, et al. Power Doppler ultrasonography and synovitis: correlating ultrasound imaging with histopathological findings and evaluating the performance of ultrasound equipments. Ann Rheum Dis 2006;65:1590-5. (Pubitemid 44799670)
14. Takase K, Ohno S, Takeno M, et al. Simultaneous evaluation of long-lasting knee synovitis in patients undergoing arthroplasty by power Doppler ultrasonography and contrast-enhanced MR in comparison with histopathology. Clin Exp Rheumatol 2012;30:85-92.
15. DAgostino MA, Conaghan P, Le BM, et al. EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritis. Ann Rheum Dis 2005;64:1703-9. (Pubitemid 41670568)
16. Kristoffersen H, Torp-Pedersen S, Terslev L, et al. Indications of inflammation visualized by ultrasound in osteoarthritis of the knee. Acta Radiol 2006;47:281-6.
17. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24. (Pubitemid 18091653)
18. Ellegaard K, Torp-Pedersen S, Lund H, et al Quantification of colour Doppler activity in the wrist in patients with rheumatoid arthritis-the reliability of different methods for image selection and evaluation. Ultraschall Med 2008;29:393-98.
19. Terslev L, von der RP, Torp-Pedersen S, et al. Diagnostic sensitivity and specificity of Doppler ultrasound in rheumatoid arthritis. J Rheumatol 2008;35:49-53.
20. Torp-Pedersen ST, Terslev L. Settings and artefacts relevant in colour/power Doppler ultrasound in rheumatology. Ann Rheum Dis 2008;67:143-9. (Pubitemid 351183300)
21. Ellegaard KM, Torp-Pedersen S, Christensen R, et al. Feasibility of a standardized ultrasound examination in patients with rheumatoid arthritis: a quality improvement among rheumatologists cohort. BMC Musculoskelet Disord 2012;13:35-43.
22. Qvistgaard E, Rogind H, Torp-Pedersen S, et al. Quantitative ultrasonography in rheumatoid arthritis: evaluation of inflammation by Doppler technique. Ann Rheum Dis 2001;60:690-3. (Pubitemid 32588373)
23. Krenn V, Morawietz L, Haupl T, et al. Grading of chronic synovitis-a histopathological grading system for molecular and diagnostic pathology. Pathol Res Pract 2002;198:317-25. (Pubitemid 34679100)
24. Semerano L, Gutierrez M, Falgarone G, et al. Diurnal variation of power Doppler in metacarpophalangeal joints of patients with rheumatoid arthritis: a preliminary study. Ann Rheum Dis 2011;70:1699-700.
25. Scire CA, Epis O, Codullo, et al. Immunohistological assessment of the synovial tissue in small joints in rheumatoid arthritis: validation of a minimally invasive ultrasound-guided synovial biopsy procedure. Arthritis Res. Ther. 2007;9:R101-9.