Recent patents on light based therapies: Photodynamic therapy, photothermal therapy and photoimmunotherapy

Recent Patents on Endocrine, Metabolic and Immune Drug Discovery

Volumn 8, Issue 1, 2014, Pages 1-8

  Sanchez Barcelo, Emilio J ^a   Mediavilla, Maria D ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

Author keywords

Cancer therapy; Microbial infections; Monoclonal antibodies (MABs); Nanoparticles; Nanovectors; Near infrared radiation (NIR); PDT; Photosensitizers; PIT; PTT; Reactive oxygen species (ROS); Singlet oxygen

Indexed keywords

MONOCLONAL ANTIBODY; PHOTOSENSITIZING AGENT; REACTIVE OXYGEN METABOLITE;

ANTIBIOTIC THERAPY; ANTIMICROBIAL THERAPY; CHEMOTHERAPY; HUMAN; IMMUNE RESPONSE; IMMUNOTHERAPY; LIGHT; PATENT; PHOTODYNAMIC THERAPY; PHOTOIMMUNOTHERAPY; PHOTOTHERAPY; PHOTOTHERMAL THERAPY; PRIORITY JOURNAL; RADIOTHERAPY; REVIEW; TARGET ORGAN; DEVICES; HYPERTHERMIC THERAPY; MOLECULARLY TARGETED THERAPY; NEOPLASMS; PHOTOCHEMOTHERAPY; PROCEDURES;

HUMANS; HYPERTHERMIA, INDUCED; IMMUNOTHERAPY; MOLECULAR TARGETED THERAPY; NEOPLASMS; PATENTS AS TOPIC; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS;

EID: 84895487409     PISSN: 18722148     EISSN: None     Source Type: Journal    
DOI: 10.2174/1872214807666131229103707     Document Type: Review

References (76)

1. Smola-Ma-kowska A, Silny W, Da-czak-Pazdrowska A, Olek-Hrab K, Ma-kowski B, OsmolaK, et al. The sun-our friend or foe? Ann Agric Environ Med 2012; 19: 805-9.
2. Shikder S, Mourshed M, Price A. Therapeutic lighting design for the elderly: A review. Perspect Public Health 2012; 132: 282-91.
3. Cesarini P. Living with the sun. Arch Pediatr 2010; 17: 910-1.
4. Mead MN. Benefits of sunlight: A bright spot for human health. Environ Health Perspect 2008; 116:160-7.
5. Münch M, Bromundt V. Light and chronobiology: Implications for health and disease. Dialogues Clin Neurosci 2012; 14: 448-53.
6. Dougherty TJ. A brief history of clinical photodynamic therapy development at Roswell Park Cancer Institute. J Clin Laser Med 1996; 14:219-21.
7. Dougherty TJ, Gomer CJ, Henderson BW, Jori G, Kessel D, Korbelik M, et al. Photodynamic therapy. J Natl Cancer Inst1998; 90: 889-905.
8. Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, et al. Photodynamic therapy of cancer: An update. CA Cancer J Clin 2011; 61: 250-81.
9. Ochsner M. Photophysical and photobiological processes in the photodynamic therapy of tumours. J Photochem Photobiol B 1997; 39: 1-18.
10. Pizova K, Tomankova K, Daskova A, Binder S, Bajgar R, Kolarova H. Photodynamic therapy for enhancing antitumour immunity. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2012; 156: 93-102.
11. Huang YY, Tanaka M, Vecchio D, Garcia-Diaz M, Chang J, Morimoto Y, et al. Photodynamic therapy induces an immune response against a bacterial pathogen. Expert Rev ClinImmunol 2012; 8: 479-94.
12. Fayter D, Corbett M, Heirs M, Fox D, Eastwood A. A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett's oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin. Health Technol Assess 2010; 14: 1-288.
13. Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR. Photodynamic therapy for infections: Clinical applications. Lasers Surg Med 2011; 43: 755-67.
14. Leggett CL, Gorospe EC, Murad MH, Montori VM, Baron TH, Wang KK. Photodynamic therapy for unresectable cholangiocarcinoma: A comparative effectiveness systematic review and metaanalyses. Photodiagnosis Photodyn Ther 2012; 9: 189-95.
15. Wainwright M. Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother 1998; 42: 13-28.
16. Hamblin MR, Hasan T. Photodynamic therapy: A new antimicrobial approach to infectious disease? Photochem Photobiol Sci 2004; 3: 436-50.
17. Warren CB, Karai LJ, Vidimos A, Maytin EV. Pain associated with aminolevulinic acid-photodynamic therapy of skin disease. J Am Acad Dermatol 2009; 61: 1033-43.
18. Attili SK, Dawe R, Ibbotson S. A review of pain experienced during topical photodynamic therapy-our experience in Dundee. Photodiagnosis Photodyn Ther 2011; 8: 53-7.
19. Chaves YN, Torezan LA, Niwa AB, Sanches Junior JA, FestaNeto C. Pain in photodynamic therapy: Mechanism of action and management strategies. An Bras Dermatol 2012; 87: 521-6.
20. Lipson RL, Baldes EJ, Olsen AM. The use of a derivative of hematoporhyrin in tumor detection. J Natl Cancer Inst 1961; 26:1-11.
21. Ormond AB, Freeman HS. Dye sensitizers for photodynamic therapy. Materials 2013; 6: 817-40.
22. Tong R, Kohane DS. Shedding light on nanomedicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2012; 4: 638-62.
23. Bergey, E., Ohulchansky, T.Y., Prasad, P.N., Pudavar, H., Roy, I. Use of photodynamic therapy therapeutic agents entrapped in ceramic nanoparticles. WO2004067508 (2004).
24. Prasad, P.N., Kim, S., Ohulchansky, T.Y., Pandey, R.K. Nanoparticles for two photon activated photodynamic therapy and imaging. WO2008030624 (2008).
25. Wang M, Abbineni G, Clevenger A, Mao C, Xu S. Upconversionnanoparticles: Synthesis, surface modification and biological applications. Nanomedicine 2011; 7: 710-29.
26. Liu Q, Sun Y, Yang T, Feng W, Li C, Li F. Sub-10 nm hexagonal lanthanide doped NaLuF4 upconversion nanocrystals for sensitivebioimaging in vivo. J Am Chem Soc 2011; 133: 17122-5.
27. Wang, Y, Wang H, Liu D, Song S, Wang X, Zhang, H. Graphene oxide covalently grafted upconversion nanoparticles for combined NIR. Biomaterials 2013; 34: 7715-24.
28. Juzeniene A, Nielsen KP, Moan J. Biophysical aspects of photodynamic therapy. J Environ Pathol Toxicol Oncol 2006; 25: 7-28.
29. Marcus SL, McIntyre WR. Photodynamic therapy systems and applications. Expert Opin Emerg Drugs 2002; 7: 321-34.
30. Brancaleon L, Moseley H. Laser and non-laser light sources for photodynamic therapy. Lasers Med Sci 2002; 17: 173-86.
31. Lundahl, S., Kozodoy, R., Carroll, R., Leppelmeier, E. Illuminator for photodynamic therapy. US8030836 (2011).
32. Anderson, R.R., Ortel, B., Battle, E.F., Joe, E.K. Methods and devices for epithelial protection during pohotodynamic therapy. US8207212 (2012).
33. Palti, Y. Treating cancer using electromagnetic fields in combination with photodynamic therapy. US8465533 (2013).
34. Woo, T., Miller, G.G., Madiyalakan, R. Method and device for photodynamic therapy. US8454991 (2013).
35. Pallenberg, A.J., Xu, L. Compositions and methods of making a photoactive agent. US8198312 (2012).
36. Kim, H.J., Lindsey, J.S. De novo synthesis of bacteriochlorins. US8173692 (2012).
37. Pandey, R.K., Sajjad, M., Pandey, S., Gryshuk, A., Oseroff, A., Nabi, H.A. Porphyrin-based compounds for tumor imaging and photodynamic therapy. US8198432 (2012).
38. Pandey, R.K., Potter, W.R., Dougherty, T.H. Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy. USRE43274 (2012).
39. Gierskcky, K.E., Moan, J., Peng, Q., Steen, H., Warloe, T., Bjorseth, A. Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy. US8410172 (2013).
40. Guo, M., Liu, Y., Kenney, M.E. Phthalocyanine salt formulations. US8440641 (2013).
41. Dei, D., Chiti, G., Nistri, D., Roncucci, G., Velders, A.H., Demartis, S., Paschetta, V. Process for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group. US8242262 (2012).
42. Baron, E.D., Berlin, J.C., Cooper, K.D., Kennedy, M.E., McCornick, T.S., Oleinick, N.L. Topical delivery of phthalocyanines. US8211883 (2012).
43. Roncucci, G., Dei, D., Giuntini, F., Chiti, G., Nistri, D., Fantelti, L., Paschetta, V., Cocchi, A. Meso-substituted porphyrins. US8288528 (2012).
44. Berg, K., Rimington, C., Selbo, P.K., Tran, D.T. Compound. US8096419 (2012).
45. Wharton, T., Gali, H., Hamblin, M.R. Photosensitizers for target photodynamic therapy. US8207211 (2012).
46. Kroto HW, Heath JR, O'Brien SC, Curl RF, Smalley RE. C60: Buckminsterfullerene. Nature 1985; 318: 162-3.
47. Brown, S.B., Griffiths, J., Mellish, K.J., O'Grady, C.C., Vernon, D.I. Biologically active methylene blue derivatives. US8188074 (2012).
48. Brevet, D., Hocine, O., Durand, J.O., Maillard, P., Morrere, A., Garcia, M., Smaïhi, M., Gary-Bobo, M. Metalloporphyrinderivates, nanoparticles comprising the same, and use thereof for photodynamic therapy. US8425879 (2013).
49. Albrecht, V., Neuberger, W., Roeder, B., Wiehe, A. Phototriggered release of active substances from dendrimerphotosensitizer complexes. US8153111 (2012).
50. Burwell, P., Chen, J.C., Wenger, T., Yeo, N. Photoreactive system and methods for prophylactic treatment of atherosclerosis. US8097028 (2012).
51. Dougherty, T.J., Grossman, Z., Kanter, P., Pandey, R.K. Chlorin and bacteriochlorin-based difunctional aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals. US8133473 (2012).
52. McCoy, C.P., Gorman, S.P., Jones D.S., Bell E.J. Polymersupported photosensitizers for the generation of single oxygen. US8450359 (2013).
53. Zhou G, Levitsky H. Towards curative cancer immunotherapy: Overcoming posttherapy tumor escape. Clin Dev Immunol 2012; Article ID: 124187.
54. Mitsunaga M, Ogawa M, Kosaka N, Rosenblum LT, Choyke PL, Kobayashi H. Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules. Nat Med 2012; 17: 1685-91.
55. Reichert JM, Dhimolea E. The future of antibodies as cancer drugs. Drug Discov Today 2012; 17: 954-63.
56. Kobayashi, H., Choike, P.L., Mitsunaga, M., Bernardo, M. Photosensitizing antibody-phuorophore conjugates. WO2013009475 (2013).
57. Mitsunaga M, Nakajima T, Sano K, Choyke PL, Kobayashi H. Near infrared theranostic photoimmunotherapy (PIT): Repeated exposure to light enhances the effects of immunoconjugate. Bioconjug Chem 2013; 23: 604-9.
58. Grobmyer SR, Krishna V. Minimally invasive cancer therapy using polyhydroxynfullerenes. Eur J Radiol 2012; 81: S51-3.
59. Young JK, Figueroa ER, Drezek RA. Tunable nanostructures as photothermal theranostic agents. Ann Biomed Eng 2012; 40: 438-59.
60. Hainfeld, J.F. Gold nanoparticles for selective IR heating. US8323694 (2012).
61. 4particles with extremely low toxicity as highly efficient near-infrared photothermal agents for in vivo tumor ablation. Nanoscale 2013; 15: 8056-66.
62. Sramek, C.K., Palanker, D.V. Method and apparatus for photothermaltherapy with adjustable spatial and/or temporal beam profile. US8496650 (2013).
63. Nanashima A, Abo T, Nonaka T, Nonaka Y, Morisaki T, Uehara R, et al. Photodynamic therapy using talaporfin sodium (Laserphyrin ®) for bile duct carcinoma: A preliminary clinical trial. Anticancer Res 2012; 32: 4931-8.
64. Yano T, Muto M, Yoshimura K, Niimi M, Ezoe Y, Yoda Y, et al. Phase I study of photodynamic therapy using talaporfin sodium and diode laser for local failure after chemoradiotherapy for esophageal cancer. Radiat Oncol 2012; 7: 113. doi:10.1186/1748-717X-7-113.
65. Akimoto J, Haraoka J, Aizawa K. Preliminary clinical report on safety and efficacy of photodynamic therapy using talaporfin sodium for malignant gliomas. Photodiagnosis Photodyn Ther 2012; 9: 91-9.
66. Dirschka T, Radny P, Dominicus R, Mensing H, Brüning H, Jenne L, et al. Long-term (6 and 12 months) follow-up of two prospective, randomized, controlled phase III trials of photodynamic therapy with BF-200 ALA and methyl aminolaevulinate for the treatment of actinic keratosis. Br J Dermatol 2013; 168: 825-36.
67. Krebs I, Vécsei Marlovits V, Bodenstorfer J, Glittenberg C, Ansari Shahrezaei S, Ristl R, et al. Comparison of Ranibizumab monotherapy versus combination of Ranibizumab with photodynamic therapy with neovascular age-related macular degeneration. Acta Ophthalmol 2013; 91: 178-83.
68. Morley S, Griffiths J, Philips G, Moseley H, O'Grady C, Mellish K, et al. Phase IIa randomized, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonized, chronic leg ulcers and diabetic foot ulcers: A new approach to antimicrobial therapy. Br J Dermatol 2013; 168: 617-24.
69. Scwingel AR, Barcessat AR, Núñez SC, Ribeiro MS. Antimicrobial photodynamic therapy in the treatment of oral candidiasis in HIV-infected patients. Photomed Laser Surg 2012; 30: 429-32.
70. Li X, Naylor MF, Le H, Nordquist RE, Teague TK, Howard CA, et al. Clinical effects of in situ photoimmunotherapy on late-stage melanoma patients: A preliminary study. Cancer Biol Ther 2010; 10: 1081-7.
71. Lindner U, Weersink RA, Haider MA, Gertner MR, Davidson SR, Atri M, et al. Image guided photothermal focal therapy for localized prostate cancer: Phase I trial. J Urol 2009; 182: 1371-7.
72. Rein ML, Deussing JM. The optogenetic (r)evolution. Mol Genet Genomics 2012; 287: 95-109.
73. Bruegmann T, Malan D, Hesse M, Beiert T, Fuegemann CJ, Fleischmann BK, et al. Optogenetic control of hearth muscle in vitro and in vivo. Nat Methods 2010; 7: 879-900.
74. Touriño C, Eban-Rothschild A, Lecea L. Optogenetics in psychiatric diseases. Curr Opin Psychiatr 2013; 23: 430-35.
75. Bernstein JG, Boyden ES. Optogenetic tools for analyzing the neural circuits of behavior. Trends Cogn Sci 2011; 15: 592-600.
76. Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, et al. Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa. Science 2010; 329: 413-7.