-
1
-
-
79960527515
-
The future of model organisms in human disease research
-
Aitman T.J., Boone C., Churchill G.A., Hengartner M.O., Mackay T.F.C., Stemple D.L. The future of model organisms in human disease research. Nat Rev Genet 2011, 12:575-582.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 575-582
-
-
Aitman, T.J.1
Boone, C.2
Churchill, G.A.3
Hengartner, M.O.4
Mackay, T.F.C.5
Stemple, D.L.6
-
2
-
-
79251581614
-
Gene set enrichment analysis of microarray data from Pimephales promelas (Rafinesque), a non-mammalian model organism
-
Thomas M.A., Yang L., Carter B.J., Klaper R.D. Gene set enrichment analysis of microarray data from Pimephales promelas (Rafinesque), a non-mammalian model organism. BMC Genomics 2011, 12:66.
-
(2011)
BMC Genomics
, vol.12
, pp. 66
-
-
Thomas, M.A.1
Yang, L.2
Carter, B.J.3
Klaper, R.D.4
-
3
-
-
77950900465
-
Systematic discovery of nonobvious human disease models through orthologous phenotypes
-
McGary K.L., Park T.J., Woods J.O., Cha H.J., Wallingford J.B., Marcotte E.M. Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci 2010, 107:6544.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 6544
-
-
McGary, K.L.1
Park, T.J.2
Woods, J.O.3
Cha, H.J.4
Wallingford, J.B.5
Marcotte, E.M.6
-
4
-
-
0031028759
-
Mouse models of human disease. Part II: recent progress and future directions
-
Bedell M.A., Largaespada D.A., Jenkins N.A., Copeland N.G. Mouse models of human disease. Part II: recent progress and future directions. Genes Dev 1997, 11:11.
-
(1997)
Genes Dev
, vol.11
, pp. 11
-
-
Bedell, M.A.1
Largaespada, D.A.2
Jenkins, N.A.3
Copeland, N.G.4
-
5
-
-
0033403663
-
Behaviour of house mice artificially selected for high levels of voluntary wheel running
-
Koteja P., Garland T., Sax J.K., Swallow J.G., Carter P.A. Behaviour of house mice artificially selected for high levels of voluntary wheel running. Anim Behav 1999, 58:1307-1318.
-
(1999)
Anim Behav
, vol.58
, pp. 1307-1318
-
-
Koteja, P.1
Garland, T.2
Sax, J.K.3
Swallow, J.G.4
Carter, P.A.5
-
6
-
-
34047146046
-
A conditional mouse model of synovial sarcoma: insights into a myogenic origin
-
Haldar M., Hancock J.D., Coffin C.M., Lessnick S.L., Capecchi M.R. A conditional mouse model of synovial sarcoma: insights into a myogenic origin. Cancer Cell 2007, 11:375-388.
-
(2007)
Cancer Cell
, vol.11
, pp. 375-388
-
-
Haldar, M.1
Hancock, J.D.2
Coffin, C.M.3
Lessnick, S.L.4
Capecchi, M.R.5
-
7
-
-
50649097473
-
Synovial sarcoma: from genetics to genetic-based animal modeling
-
Haldar M., Randall R.L., Capecchi M.R. Synovial sarcoma: from genetics to genetic-based animal modeling. Clin Orthop Relat Res 2008, 466:2156-2167.
-
(2008)
Clin Orthop Relat Res
, vol.466
, pp. 2156-2167
-
-
Haldar, M.1
Randall, R.L.2
Capecchi, M.R.3
-
8
-
-
80052768892
-
Discovering novel subsystems using comparative genomics
-
Ferrer L., Shearer A.G., Karp P.D. Discovering novel subsystems using comparative genomics. Bioinformatics 2011, 27:2478-2485.
-
(2011)
Bioinformatics
, vol.27
, pp. 2478-2485
-
-
Ferrer, L.1
Shearer, A.G.2
Karp, P.D.3
-
9
-
-
26444608611
-
Discovering statistically significant pathways in expression profiling studies
-
Tian L., Greenberg S.A., Kong S.W., Altschuler J., Kohane I.S., Park P.J. Discovering statistically significant pathways in expression profiling studies. Proc Natl Acad Sci USA 2005, 102:13544-13549.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13544-13549
-
-
Tian, L.1
Greenberg, S.A.2
Kong, S.W.3
Altschuler, J.4
Kohane, I.S.5
Park, P.J.6
-
10
-
-
36849004088
-
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
-
Bebek G., Yang J. PathFinder: mining signal transduction pathway segments from protein-protein interaction networks. BMC Bioinformatics 2007, 8:335.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 335
-
-
Bebek, G.1
Yang, J.2
-
11
-
-
35748980569
-
Mining biological networks for unknown pathways
-
Cakmak A., Ozsoyoglu G. Mining biological networks for unknown pathways. Bioinformatics 2007, 23:2775.
-
(2007)
Bioinformatics
, vol.23
, pp. 2775
-
-
Cakmak, A.1
Ozsoyoglu, G.2
-
12
-
-
70449371150
-
Identification of genes involved in the same pathways using a Hidden Markov model-based approach
-
Senf A., Chen X.-W. Identification of genes involved in the same pathways using a Hidden Markov model-based approach. Bioinformatics 2009, 25:2945-2954.
-
(2009)
Bioinformatics
, vol.25
, pp. 2945-2954
-
-
Senf, A.1
Chen, X.-W.2
-
13
-
-
75549090213
-
KEGG for representation and analysis of molecular networks involving diseases and drugs
-
Kanehisa M., Goto S., Furumichi M., Tanabe M., Hirakawa M. KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res 2010, 38:D355.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Kanehisa, M.1
Goto, S.2
Furumichi, M.3
Tanabe, M.4
Hirakawa, M.5
-
14
-
-
33644873184
-
BioGRID: a general repository for interaction datasets
-
Stark C., Breitkreutz B.J., Reguly T., Boucher L., Breitkreutz A., Tyers M. BioGRID: a general repository for interaction datasets. Nucleic Acids Res 2006, 34:D535-D539.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Stark, C.1
Breitkreutz, B.J.2
Reguly, T.3
Boucher, L.4
Breitkreutz, A.5
Tyers, M.6
-
15
-
-
0034069495
-
Gene ontology: tool for the unification of biology
-
Ashburner M., Ball C.A., Blake J.A., Botstein D., Butler H., Cherry J.M., et al. Gene ontology: tool for the unification of biology. Nat Genet 2000, 25:25.
-
(2000)
Nat Genet
, vol.25
, pp. 25
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
Botstein, D.4
Butler, H.5
Cherry, J.M.6
-
16
-
-
84880812972
-
Mining disease fingerprints from within genetic pathways. In: Annual AMIA symbosium. Chicago, IL
-
Nabhan AR, Sarkar IN. Mining disease fingerprints from within genetic pathways. In: Annual AMIA symbosium. Chicago, IL; 2012.
-
(2012)
-
-
Nabhan, A.R.1
Sarkar, I.N.2
-
17
-
-
58149193222
-
Human protein reference database - 2009 update
-
Prasad T.S.K., Goel R., Kandasamy K., Keerthikumar S., Kumar S., Mathivanan S., et al. Human protein reference database - 2009 update. Nucleic Acids Res 2009, 37:D767-D772.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Prasad, T.S.K.1
Goel, R.2
Kandasamy, K.3
Keerthikumar, S.4
Kumar, S.5
Mathivanan, S.6
-
18
-
-
78149333073
-
gSpan: graph-based substructure pattern mining.
-
Yan X, Han J. gSpan: graph-based substructure pattern mining. IEEE; 2002. p. 721-4.
-
(2002)
IEEE
, pp. 721-724
-
-
Yan, X.1
Han, J.2
-
19
-
-
85025192644
-
The graph isomorphism disease
-
Read R.C., Corneil D.G. The graph isomorphism disease. J Graph Theory 1977, 1:339-363.
-
(1977)
J Graph Theory
, vol.1
, pp. 339-363
-
-
Read, R.C.1
Corneil, D.G.2
-
21
-
-
78651324347
-
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
-
Szklarczyk D., Franceschini A., Kuhn M., Simonovic M., Roth A., Minguez P., et al. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res 2011, 39:D561-D568.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Szklarczyk, D.1
Franceschini, A.2
Kuhn, M.3
Simonovic, M.4
Roth, A.5
Minguez, P.6
-
22
-
-
38549117301
-
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
-
Caspi R., Foerster H., Fulcher C.A., Kaipa P., Krummenacker M., Latendresse M., et al. The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res 2008, 36:D623-D631.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Caspi, R.1
Foerster, H.2
Fulcher, C.A.3
Kaipa, P.4
Krummenacker, M.5
Latendresse, M.6
-
23
-
-
0033954256
-
The protein data bank
-
Berman H.M., Westbrook J., Feng Z., Gilliland G., Bhat T., Weissig H., et al. The protein data bank. Nucleic Acids Res 2000, 28:235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.5
Weissig, H.6
-
24
-
-
58349111875
-
AmiGO: online access to ontology and annotation data
-
Carbon S., Ireland A., Mungall C.J., Shu S.Q., Marshall B., Lewis S. AmiGO: online access to ontology and annotation data. Bioinformatics 2009, 25:288-289.
-
(2009)
Bioinformatics
, vol.25
, pp. 288-289
-
-
Carbon, S.1
Ireland, A.2
Mungall, C.J.3
Shu, S.Q.4
Marshall, B.5
Lewis, S.6
-
25
-
-
48349105261
-
WikiPathways: pathway editing for the people
-
Pico A.R., Kelder T., Van Iersel M.P., Hanspers K., Conklin B.R., Evelo C. WikiPathways: pathway editing for the people. PLoS Biol 2008, 6:e184.
-
(2008)
PLoS Biol
, vol.6
-
-
Pico, A.R.1
Kelder, T.2
Van Iersel, M.P.3
Hanspers, K.4
Conklin, B.R.5
Evelo, C.6
-
26
-
-
84865549088
-
AraPath: a knowledgebase for pathway analysis in Arabidopsis
-
Lai L., Liberzon A., Hennessey J., Jiang G., Qi J., Mesirov J.P., et al. AraPath: a knowledgebase for pathway analysis in Arabidopsis. Bioinformatics 2012, 28:2291-2292.
-
(2012)
Bioinformatics
, vol.28
, pp. 2291-2292
-
-
Lai, L.1
Liberzon, A.2
Hennessey, J.3
Jiang, G.4
Qi, J.5
Mesirov, J.P.6
-
27
-
-
58149194606
-
The Rat Genome Database 2009: variation, ontologies and pathways
-
Dwinell M.R., Worthey E.A., Shimoyama M., Bakir-Gungor B., DePons J., Laulederkind S., et al. The Rat Genome Database 2009: variation, ontologies and pathways. Nucleic Acids Res 2009, 37:D744-D749.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Dwinell, M.R.1
Worthey, E.A.2
Shimoyama, M.3
Bakir-Gungor, B.4
DePons, J.5
Laulederkind, S.6
-
28
-
-
48649088341
-
Catch of the day: zebrafish as a human cancer model
-
Stoletov K., Klemke R. Catch of the day: zebrafish as a human cancer model. Oncogene 2008, 27:4509-4520.
-
(2008)
Oncogene
, vol.27
, pp. 4509-4520
-
-
Stoletov, K.1
Klemke, R.2
-
29
-
-
0043240183
-
Cancer genetics and drug discovery in the zebrafish
-
Stern H.M., Zon L.I. Cancer genetics and drug discovery in the zebrafish. Nat Rev Cancer 2003, 3:533-539.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 533-539
-
-
Stern, H.M.1
Zon, L.I.2
-
30
-
-
51049109252
-
Zebrafish as a cancer model
-
Feitsma H., Cuppen E. Zebrafish as a cancer model. Mol Cancer Res 2008, 6:685-694.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 685-694
-
-
Feitsma, H.1
Cuppen, E.2
-
31
-
-
51249096960
-
Zebrafish as a model for infectious disease and immune function
-
Sullivan C., Kim C.H. Zebrafish as a model for infectious disease and immune function. Fish Shellfish Immunol 2008, 25:341-350.
-
(2008)
Fish Shellfish Immunol
, vol.25
, pp. 341-350
-
-
Sullivan, C.1
Kim, C.H.2
-
32
-
-
12144273121
-
In vivo drug discovery in the zebrafish
-
Zon L.I., Peterson R.T. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 2005, 4:35-44.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 35-44
-
-
Zon, L.I.1
Peterson, R.T.2
-
33
-
-
0024461293
-
REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase
-
Morrison A., Christensen R., Alley J., Beck A., Bernstine E., Lemontt J., et al. REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. J Bacteriol 1989, 171:5659-5667.
-
(1989)
J Bacteriol
, vol.171
, pp. 5659-5667
-
-
Morrison, A.1
Christensen, R.2
Alley, J.3
Beck, A.4
Bernstine, E.5
Lemontt, J.6
-
34
-
-
79958106597
-
The replisome pausing factor timeless is required for episomal maintenance of latent Epstein-Barr virus
-
Dheekollu J., Lieberman P.M. The replisome pausing factor timeless is required for episomal maintenance of latent Epstein-Barr virus. J Virolgy 2011, 85:5853-5863.
-
(2011)
J Virolgy
, vol.85
, pp. 5853-5863
-
-
Dheekollu, J.1
Lieberman, P.M.2
-
35
-
-
84861235431
-
Mining electronic health records: towards better research applications and clinical care
-
Jensen P.B., Jensen L.J., Brunak S.R. Mining electronic health records: towards better research applications and clinical care. Nat Rev Genet 2012, 13:395-405.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 395-405
-
-
Jensen, P.B.1
Jensen, L.J.2
Brunak, S.R.3
-
36
-
-
13444266370
-
Online mendelian inheritance in man (OMIM), a knowledgebase of human genes and genetic disorders
-
Hamosh A., Scott A.F., Amberger J.S., Bocchini C.A., McKusick V.A. Online mendelian inheritance in man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res 2005, 33:D514-D517.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.S.3
Bocchini, C.A.4
McKusick, V.A.5
-
37
-
-
10744224197
-
Development of human protein reference database as an initial platform for approaching systems biology in humans
-
Peri S., Navarro J.D., Amanchy R., Kristiansen T.Z., Jonnalagadda C.K., Surendranath V., et al. Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res 2003, 13:2363-2371.
-
(2003)
Genome Res
, vol.13
, pp. 2363-2371
-
-
Peri, S.1
Navarro, J.D.2
Amanchy, R.3
Kristiansen, T.Z.4
Jonnalagadda, C.K.5
Surendranath, V.6
-
38
-
-
65549102777
-
Protein-protein interaction databases: keeping up with growing interactomes
-
Lehne B., Schlitt T. Protein-protein interaction databases: keeping up with growing interactomes. Hum Genomics 2009, 3:291-297.
-
(2009)
Hum Genomics
, vol.3
, pp. 291-297
-
-
Lehne, B.1
Schlitt, T.2
-
39
-
-
13444259844
-
Reactome: a knowledgebase of biological pathways
-
Joshi-Tope G., Gillespie M., Vastrik I., D'Eustachio P., Schmidt E., de Bono B., et al. Reactome: a knowledgebase of biological pathways. Nucleic Acids Res 2005, 33:D428-D432.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Joshi-Tope, G.1
Gillespie, M.2
Vastrik, I.3
D'Eustachio, P.4
Schmidt, E.5
de Bono, B.6
-
40
-
-
75549084124
-
WormBase: a comprehensive resource for nematode research
-
Harris T.W., Antoshechkin I., Bieri T., Blasiar D., Chan J., Chen W.J., et al. WormBase: a comprehensive resource for nematode research. Nucleic Acids Res 2010, 38:D463-D467.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Harris, T.W.1
Antoshechkin, I.2
Bieri, T.3
Blasiar, D.4
Chan, J.5
Chen, W.J.6
-
41
-
-
84859197018
-
Taming verification hardness: an efficient algorithm for testing subgraph isomorphism
-
Shang H., Zhang Y., Lin X., Yu J.X. Taming verification hardness: an efficient algorithm for testing subgraph isomorphism. Proc VLDB Endowment 2008, 1:364-375.
-
(2008)
Proc VLDB Endowment
, vol.1
, pp. 364-375
-
-
Shang, H.1
Zhang, Y.2
Lin, X.3
Yu, J.X.4
-
42
-
-
0030287048
-
The expectation-maximization algorithm
-
Moon T.K. The expectation-maximization algorithm. Signal Process Mag, IEEE 1996, 13:47-60.
-
(1996)
Signal Process Mag, IEEE
, vol.13
, pp. 47-60
-
-
Moon, T.K.1
|