Analysis of complications in 430 consecutive pediatric patients treated with intrathecal baclofen therapy: 14-year experience

Journal of Neurosurgery: Pediatrics

Volumn 13, Issue 3, 2014, Pages 301-306

  Motta, Francesco ^a   Antonello, Clara E ^a  

^a V BUZZI CHILDREN S HOSPITAL   (Italy)

Author keywords

Adverse event; Cerebral palsy; Functional neurosurgery; Infection; Intrathecal baclofen; Subfascial

Indexed keywords

ANTIBIOTIC AGENT; BACLOFEN;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; CATHETER COMPLICATION; CEREBRAL PALSY; CHILD; CONTROLLED STUDY; DYSTONIA; FEMALE; FOLLOW UP; HUMAN; INFECTION; INTRATHECAL CATHETER; INTRATHECAL PUMP; LIQUORRHEA; MAJOR CLINICAL STUDY; MALE; MEDICAL DEVICE COMPLICATION; PEDIATRICS; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SPASTICITY;

ADOLESCENT; BACLOFEN; CATHETERS, INDWELLING; CEREBRAL PALSY; CHILD; CHILD, PRESCHOOL; DYSTONIA; DYSTONIC DISORDERS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFECTION; INFUSION PUMPS, IMPLANTABLE; INJECTIONS, SPINAL; KAPLAN-MEIER ESTIMATE; MALE; MUSCLE RELAXANTS, CENTRAL; MUSCLE SPASTICITY; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84895432781     PISSN: 19330707     EISSN: 19330715     Source Type: Journal    
DOI: 10.3171/2013.11.PEDS13253     Document Type: Article

References (35)

1. Albright AL, Barry MJ, Shafton DH, Ferson SS: Intrathecal baclofen for generalized dystonia. Dev Med Child Neurol 43:652-657, 2001 (Pubitemid 32982225)
2. Albright AL, Cervi A, Singletary J: Intrathecal baclofen for spasticity in cerebral palsy. JAMA 265:1418-1422, 1991
3. Albright AL, Ferson SS: Intrathecal baclofen therapy in children. Neurosurg Focus 21(2):E3, 2006
4. Albright AL, Turner M, Pattisapu JV: Best-practice surgical techniques for intrathecal baclofen therapy. J Neurosurg 104 (4 Suppl):233-239, 2006 (Pubitemid 44968421)
5. Alden TD, Lytle RA, Park TS, Noetzel MJ, Ojemann JG: Intrathecal baclofen withdrawal: a case report and review of the literature. Childs Nerv Syst 18:522-525, 2002 (Pubitemid 36013706)
6. Ammar A, Ughratdar I, Sivakumar G, Vloeberghs MH: Intrathecal baclofen therapy - how we do it. Technical note. J Neurosurg Pediatr 10:439-444, 2012
7. Awaad Y, Rizk T, Siddiqui I, Roosen N, McIntosh K, Waines GM: Complications of intrathecal baclofen pump: prevention and cure. ISRN Neurol 2012:575168, 2012
8. Bonouvrié LA, van Schie PE, Becher JG, van Ouwerkerk WJ, Reeuwijk A, Jeroen Vermeulen R: Effects of intrathecal baclofen on daily care in children with secondary generalized dystonia: a pilot study. Eur J Paediatr Neurol 15:539-543, 2011
9. Borowski A, Littleton AG, Borkhuu B, Presedo A, Shah S, Dabney KW, et al: Complications of intrathecal baclofen pump therapy in pediatric patients. J Pediatr Orthop 30:76-81, 2010
10. Brennan PM, Whittle IR: Intrathecal baclofen therapy for neurological disorders: a sound knowledge base but many challenges remain. Br J Neurosurg 22:508-519, 2008
11. Butler C, Campbell S: Evidence of the effects of intrathecal baclofen for spastic and dystonic cerebral palsy. Dev Med Child Neurol 42:634-645, 2000
12. Dan B, Motta F, Vles JS, Vloeberghs M, Becher JG, Eunson P, et al: Consensus on the appropriate use of intrathecal baclofen (ITB) therapy in paediatric spasticity. Eur J Paediatr Neurol 14:19-28, 2010
13. Dvorak EM, McGuire JR, Nelson ME: Incidence and identification of intrathecal baclofen catheter malfunction. PM R 2:751-756, 2010
14. Fjelstad AB, Hommelstad J, Sorteberg A: Infections related to intrathecal baclofen therapy in children and adults: frequency and risk factors. Clinical article. J Neurosurg Pediatr 4:487-493, 2009
15. Gerszten PC, Albright AL, Johnstone GF: Intrathecal baclofen infusion and subsequent orthopedic surgery in patients with spastic cerebral palsy. J Neurosurg 88:1009-1013, 1998 (Pubitemid 28261847)
16. Gooch JL, Oberg WA, Grams B, Ward LA, Walker ML: Complications of intrathecal baclofen pumps in children. Pediatr Neurosurg 39:1-6, 2003 (Pubitemid 36649389)
17. Haranhalli N, Anand D, Wisoff JH, Harter DH, Weiner HL, Blate M, et al: Intrathecal baclofen therapy: complication avoidance and management. Childs Nerv Syst 27:421-427, 2011
18. Himmelmann K, Hagberg G, Uvebrant P: The changing panorama of cerebral palsy in Sweden. X. Prevalence and origin in the birth-year period 1999-2002. Acta Paediatr 99:1337-1343, 2010
19. Hoving MA, van Raak EP, Spincemaille GH, Palmans LJ, Becher JG, Vles JS: Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a randomised controlled trial. Eur J Paediatr Neurol 13:240-246, 2009
20. Kolaski K, Logan LR: A review of the complications of intrathecal baclofen in patients with cerebral palsy. NeuroRehabilitation 22:383-395, 2007
21. Kopell BH, Sala D, Doyle WK, Feldman DS, Wisoff JH, Weiner HL: Subfascial implantation of intrathecal baclofen pumps in children: technical note. Neurosurgery 49:753-757, 2001 (Pubitemid 32769770)
22. Krach LE: Intrathecal baclofen use in adults with cerebral palsy. Dev Med Child Neurol 51 (Suppl 4):106-112, 2009
23. Miracle AC, Fox MA, Ayyangar RN, Vyas A, Mukherji SK, Quint DJ: Imaging evaluation of intrathecal baclofen pump-catheter systems. AJNR Am J Neuroradiol 32:1158-1164, 2011
24. Motta F, Buonaguro V, Stignani C: The use of intrathecal baclofen pump implants in children and adolescents: safety and complications in 200 consecutive cases. J Neurosurg 107 (1 Suppl):32-35, 2007
25. Motta F, Stignani C, Antonello CE: Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. J Pediatr Orthop 28:213-217, 2008 (Pubitemid 351506322)
26. Murphy NA, Irwin MC, Hoff C: Intrathecal baclofen therapy in children with cerebral palsy: efficacy and complications. Arch Phys Med Rehabil 83:1721-1725, 2002 (Pubitemid 35424693)
27. Nielsen JF, Hansen HJ, Sunde N, Christensen JJ: Evidence of tolerance to baclofen in treatment of severe spasticity with intrathecal baclofen. Clin Neurol Neurosurg 104:142-145, 2002 (Pubitemid 34262654)
28. Palisano RJ, Hanna SE, Rosenbaum PL, Russell DJ, Walter SD, Wood EP, et al: Validation of a model of gross motor function for children with cerebral palsy. Phys Ther 80:974-985, 2000
29. Shirley KW, Kothare S, Piatt JH Jr, Adirim TA: Intrathecal baclofen overdose and withdrawal. Pediatr Emerg Care 22:258-261, 2006 (Pubitemid 43772178)
30. Taira T, Ueta T, Katayama Y, Kimizuka M, Nemoto A, Mizusawa H, et al: Rate of complications among the recipients of intrathecal baclofen pump in Japan: a multicenter study. Neuromodulation 16:266-272, 2013
31. Varhabhatla NC, Zuo Z: Rising complication rates after intrathecal catheter and pump placement in the pediatric population: analysis of national data between 1997 and 2006. Pain Physician 15:65-74, 2012
32. Vender JR, Hester S, Waller JL, Rekito A, Lee MR: Identification and management of intrathecal baclofen pump complications: a comparison of pediatric and adult patients. J Neurosurg 104 (1 Suppl):9-15, 2006
33. Ward A, Hayden S, Dexter M, Scheinberg A: Continuous intrathecal baclofen for children with spasticity and/or dystonia: Goal attainment and complications associated with treatment. J Paediatr Child Health 45:720-726, 2009
34. Williams BS, Christo PJ: Obstructed catheter connection pin discovered during intrathecal baclofen pump exchange. Clin J Pain 25:256-259, 2009
35. Zdolsek HA, Olesch C, Antolovich G, Reddihough D: Intrathecal baclofen therapy: benefits and complications. J Intellect Dev Disabil 36:207-213, 2011