메뉴 건너뛰기




Volumn 53, Issue 5, 2014, Pages 361-365

Biomarkers for multiple sclerosis

Author keywords

Biomarker; Cerebrospinal fluid; Flow cytometry; Multiple sclerosis

Indexed keywords

BETA INTERFERON; BIOLOGICAL MARKER; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; COMPLEMENT FACTOR H; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GELATINASE B; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 8; L SELECTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; NATALIZUMAB; OLIGOCLONAL BAND; RANTES; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84895198226     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.53.1246     Document Type: Review
Times cited : (37)

References (43)
  • 1
    • 34548133584 scopus 로고    scopus 로고
    • Multiple sclerosis: A complicated picture of autoimmunity
    • McFarland HF, Martin R. Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol 8: 913-919, 2007.
    • (2007) Nat Immunol , vol.8 , pp. 913-919
    • McFarland, H.F.1    Martin, R.2
  • 2
    • 9044245703 scopus 로고    scopus 로고
    • Guidelines for the use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis
    • Miller DH, Albert PS, Barkhof F, et al. Guidelines for the use of magnetic resonance techniques in monitoring the treatment of multiple sclerosis. Ann Neurol 39: 6-16, 1996.
    • (1996) Ann Neurol , vol.39 , pp. 6-16
    • Miller, D.H.1    Albert, P.S.2    Barkhof, F.3
  • 3
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
    • Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 69: 292-302, 2011.
    • (2011) Ann Neurol , vol.69 , pp. 292-302
    • Polman, C.H.1    Reingold, S.C.2    Banwell, B.3
  • 4
    • 12344331799 scopus 로고    scopus 로고
    • Ologoclonal IgG bands in Japanese patients with multiple sclerosis. A comparative study between isoelectric focusing with IgG immunofixation and high-resolution agarose gel electrophoresis
    • Nakashima I, Fujihara K, Sato S, Itoyama Y. Ologoclonal IgG bands in Japanese patients with multiple sclerosis. A comparative study between isoelectric focusing with IgG immunofixation and high-resolution agarose gel electrophoresis. J Neuroimmunol 159: 133-136, 2005.
    • (2005) J Neuroimmunol , vol.159 , pp. 133-136
    • Nakashima, I.1    Fujihara, K.2    Sato, S.3    Itoyama, Y.4
  • 5
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13: 227-231, 1983.
    • (1983) Ann Neurol , vol.13 , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 6
    • 0242300587 scopus 로고    scopus 로고
    • Cerebrospinal fluid oligoclonal band in the diagnosis of multiple aclerosis
    • Fortini A, Sanders E, Weisnenker B, et al. Cerebrospinal fluid oligoclonal band in the diagnosis of multiple aclerosis. Am J Clin Pathol 120: 672-675, 2003.
    • (2003) Am J Clin Pathol , vol.120 , pp. 672-675
    • Fortini, A.1    Sanders, E.2    Weisnenker, B.3
  • 7
    • 33750604563 scopus 로고    scopus 로고
    • Oligoclonal bands in multiple sclerosis cerebrospinal fluid: An update on methodology and clinical usefulness
    • Link H, Huang Y-M. Oligoclonal bands in multiple sclerosis cerebrospinal fluid: an update on methodology and clinical usefulness. J Neuroimmunol 180: 17-28, 2006.
    • (2006) J Neuroimmunol , vol.180 , pp. 17-28
    • Link, H.1    Huang, Y.-M.2
  • 8
    • 0032723033 scopus 로고    scopus 로고
    • Oligoclonal IgG bands in Japanese multiple sclerosis patients
    • Nakashima I, Fujihara K, Itoyama Y. Oligoclonal IgG bands in Japanese multiple sclerosis patients. J Neuroimmunol 101: 205-206, 1999.
    • (1999) J Neuroimmunol , vol.101 , pp. 205-206
    • Nakashima, I.1    Fujihara, K.2    Itoyama, Y.3
  • 9
    • 0019952759 scopus 로고
    • Oligoclonal IgG in multiple sclerosis and subacute sclerosing panencephalitis brains
    • Mattson DH, Roos RP, Arnason BGW. Oligoclonal IgG in multiple sclerosis and subacute sclerosing panencephalitis brains. J Neuroimmunol 2: 261-276, 1982.
    • (1982) J Neuroimmunol , vol.2 , pp. 261-276
    • Mattson, D.H.1    Roos, R.P.2    Arnason, B.G.W.3
  • 10
    • 0023032750 scopus 로고
    • Quantitative cerebrospinal fluid IgG measurements as a marker of disease activity in multiple sclerosis
    • Caroscio JT, Kochwa S, Sacks H, Makuku S, Cohen JA, Yahr MD. Quantitative cerebrospinal fluid IgG measurements as a marker of disease activity in multiple sclerosis. Arch Neurol 43: 1129-1131, 1986.
    • (1986) Arch Neurol , vol.43 , pp. 1129-1131
    • Caroscio, J.T.1    Kochwa, S.2    Sacks, H.3    Makuku, S.4    Cohen, J.A.5    Yahr, M.D.6
  • 11
    • 0017816212 scopus 로고
    • Multiple sclerosis: The blood-brainbarrier and the measurement of de novo central nervous system IgG synthesis
    • Tourtellotte WW, Ma BI. Multiple sclerosis: the blood-brainbarrier and the measurement of de novo central nervous system IgG synthesis. Neurology 28: 76-83, 1978.
    • (1978) Neurology , vol.28 , pp. 76-83
    • Tourtellotte, W.W.1    Ma, B.I.2
  • 13
    • 10344250945 scopus 로고    scopus 로고
    • A serum autoantibody marker of neuromyelitis optica: Distinction from multiple sclerosis
    • Lennon VA, Wingerchuk DM, Kryzer TJ, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 364: 2106-2112, 2004.
    • (2004) Lancet , vol.364 , pp. 2106-2112
    • Lennon, V.A.1    Wingerchuk, D.M.2    Kryzer, T.J.3
  • 14
    • 77954650841 scopus 로고    scopus 로고
    • EFNS guidelines on diagnosis and management of neuromyelitis optica
    • Sellner J, Boggild M, Clanet M, et al. EFNS guidelines on diagnosis and management of neuromyelitis optica. Eur J Neurol 17: 1019-1032, 2010.
    • (2010) Eur J Neurol , vol.17 , pp. 1019-1032
    • Sellner, J.1    Boggild, M.2    Clanet, M.3
  • 15
    • 0032975730 scopus 로고    scopus 로고
    • Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
    • van Boxel-Dezaire AHH, Hoff SCH, van Oosten BW, et al. Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann Neurol 45: 695-703, 1999.
    • (1999) Ann Neurol , vol.45 , pp. 695-703
    • van Boxel-Dezaire, A.H.H.1    Hoff, S.C.H.2    van Oosten, B.W.3
  • 16
    • 0028985320 scopus 로고
    • Tumor necrosis factor-〈 messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
    • Riekmann P, Albrecht M, Kitze B, et al. Tumor necrosis factor-〈 messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 37: 82-88, 1995.
    • (1995) Ann Neurol , vol.37 , pp. 82-88
    • Riekmann, P.1    Albrecht, M.2    Kitze, B.3
  • 17
    • 0031778459 scopus 로고    scopus 로고
    • Correlating immunological and magnetic resonance imaging markers of disease activity in multiple sclerosis
    • Giovannoni G, Kieseier B, Hartung HP. Correlating immunological and magnetic resonance imaging markers of disease activity in multiple sclerosis. J Neurol Neurosurg Psychiatry 64 (suppl): S31- S36, 1998.
    • (1998) J Neurol Neurosurg Psychiatry , vol.64 , Issue.SUPPL.
    • Giovannoni, G.1    Kieseier, B.2    Hartung, H.P.3
  • 18
    • 0036096668 scopus 로고    scopus 로고
    • Longitudinal study of antimyelin T-cell reactivity in relapsing-remitting multiple sclerosis: Association with clinical and MRI activity
    • Hellings N, Gelin G, Medaer R, et al. Longitudinal study of antimyelin T-cell reactivity in relapsing-remitting multiple sclerosis: association with clinical and MRI activity. J Neuroimmunol 126: 143-160, 2002.
    • (2002) J Neuroimmunol , vol.126 , pp. 143-160
    • Hellings, N.1    Gelin, G.2    Medaer, R.3
  • 19
    • 0029112447 scopus 로고
    • Circulating adhesion correlation with magnetic resonance imaging
    • Hartung H-P, Reiners K, Archelos JJ, et al. Circulating adhesion correlation with magnetic resonance imaging. Ann Neurol 38: 186-193, 1995.
    • (1995) Ann Neurol , vol.38 , pp. 186-193
    • Hartung, H.-P.1    Reiners, K.2    Archelos, J.J.3
  • 20
    • 0029758280 scopus 로고    scopus 로고
    • Soluble intercellular adhesion molecule-1 in serum and cerebrospinal fluid of clinically active relapsing-remitting multiple sclerosis: Correlation with Gd- DTPA magnetic resonance imaging-enhancement and cerebrospinal fluid findings
    • Trojano M, Avolio C, Simone IL, et al. Soluble intercellular adhesion molecule-1 in serum and cerebrospinal fluid of clinically active relapsing-remitting multiple sclerosis: correlation with Gd- DTPA magnetic resonance imaging-enhancement and cerebrospinal fluid findings. Neurology 47: 1535-1541, 1996.
    • (1996) Neurology , vol.47 , pp. 1535-1541
    • Trojano, M.1    Avolio, C.2    Simone, I.L.3
  • 21
    • 0032693982 scopus 로고    scopus 로고
    • Serum MMP-9 and TIMP- 1 levels are related to MRI activity in relapsing multiple sclerosis
    • Waubant E, Goodkin DE, Gee L, et al. Serum MMP-9 and TIMP- 1 levels are related to MRI activity in relapsing multiple sclerosis. Neurology 53: 1397-1401, 1999.
    • (1999) Neurology , vol.53 , pp. 1397-1401
    • Waubant, E.1    Goodkin, D.E.2    Gee, L.3
  • 22
    • 77952991177 scopus 로고    scopus 로고
    • Complement regulator factor H as a serum biomarker of multiple sclerosis disease state
    • Ingram G, Hakobyan S, Hirst CL, et al. Complement regulator factor H as a serum biomarker of multiple sclerosis disease state. Brain 133: 1602-1611, 2010.
    • (2010) Brain , vol.133 , pp. 1602-1611
    • Ingram, G.1    Hakobyan, S.2    Hirst, C.L.3
  • 23
    • 0035479146 scopus 로고    scopus 로고
    • Tc1/Tc2 and Th1/Th2 balance in Asian and Western types of multiple sclerosis, HTLV-Iassociated myelopathy/tropical spastic paraparesis and hyper- IgEaemic myelitis
    • Ochi H, Wu X-M, Osoegawa M, et al. Tc1/Tc2 and Th1/Th2 balance in Asian and Western types of multiple sclerosis, HTLV-Iassociated myelopathy/tropical spastic paraparesis and hyper- IgEaemic myelitis. J Neuroimmunol 119: 297-305, 2001.
    • (2001) J Neuroimmunol , vol.119 , pp. 297-305
    • Ochi, H.1    Wu, X.-M.2    Osoegawa, M.3
  • 24
    • 1242264279 scopus 로고    scopus 로고
    • Immunomonitoring measures in relapsing-remitting multiple sclerosis
    • Matsui M, Araya S, Wang HY, Matsushima K, Saida T. Immunomonitoring measures in relapsing-remitting multiple sclerosis. J Neuroimmunol 148: 192-199, 2004.
    • (2004) J Neuroimmunol , vol.148 , pp. 192-199
    • Matsui, M.1    Araya, S.2    Wang, H.Y.3    Matsushima, K.4    Saida, T.5
  • 25
    • 0037105990 scopus 로고    scopus 로고
    • Increased IL-13 but not IL- 5 production by CD4-positive T cells and CD8-positive T cells in multiple sclerosis during relapse phase
    • Ochi H, Osoegawa M, Wu X-M, et al. Increased IL-13 but not IL- 5 production by CD4-positive T cells and CD8-positive T cells in multiple sclerosis during relapse phase. J Neurol Sci 201: 45-51, 2002.
    • (2002) J Neurol Sci , vol.201 , pp. 45-51
    • Ochi, H.1    Osoegawa, M.2    Wu, X.-M.3
  • 27
    • 0035283409 scopus 로고    scopus 로고
    • Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: Imbalance of Th1/Th2-associated chemokine signaling
    • Misu T, Onodera H, Fujihara K, et al. Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling. J Neuroimmunol 114: 207-212, 2001.
    • (2001) J Neuroimmunol , vol.114 , pp. 207-212
    • Misu, T.1    Onodera, H.2    Fujihara, K.3
  • 28
    • 0036889725 scopus 로고    scopus 로고
    • Chemokine receptors associated with immunity within and outside the central nervous system in early rerapsing-remitting multiple sclerosis
    • Wang HY, Matsui M, Araya S, Onai N, Matsushima K, Saida T. Chemokine receptors associated with immunity within and outside the central nervous system in early rerapsing-remitting multiple sclerosis. J Neuroimmunol 133: 184-192, 2002.
    • (2002) J Neuroimmunol , vol.133 , pp. 184-192
    • Wang, H.Y.1    Matsui, M.2    Araya, S.3    Onai, N.4    Matsushima, K.5    Saida, T.6
  • 29
    • 0031721520 scopus 로고    scopus 로고
    • Increased release of interleukin-12p40 in MS: Association with intracerebral inflammation
    • Fassbender K, Ragoschke A, Rossol S, et al. Increased release of interleukin-12p40 in MS: association with intracerebral inflammation. Neurology 51: 753-758, 1998.
    • (1998) Neurology , vol.51 , pp. 753-758
    • Fassbender, K.1    Ragoschke, A.2    Rossol, S.3
  • 30
    • 21044448355 scopus 로고    scopus 로고
    • Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis
    • Ishizu T, Osoegawa M, Mei F-J, et al. Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis. Brain 128: 988-1002, 2005.
    • (2005) Brain , vol.128 , pp. 988-1002
    • Ishizu, T.1    Osoegawa, M.2    Mei, F.-J.3
  • 31
    • 0028988350 scopus 로고
    • Macrophage inflammatory protein-1〈 in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological diseases
    • Miyagishi R, Kikuchi S, Fukazawa T, Tashiro K. Macrophage inflammatory protein-1〈 in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological diseases. J Neurol Sci 129: 223-227, 1995.
    • (1995) J Neurol Sci , vol.129 , pp. 223-227
    • Miyagishi, R.1    Kikuchi, S.2    Fukazawa, T.3    Tashiro, K.4
  • 32
    • 0033559346 scopus 로고    scopus 로고
    • Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
    • Sørensen TL, Tani M, Jensen J, et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest 103: 807-815, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 807-815
    • Sørensen, T.L.1    Tani, M.2    Jensen, J.3
  • 33
    • 0035552160 scopus 로고    scopus 로고
    • Chemokines CXCL10 and CCL2. differential involvement in intrathecal inflammation in multiple sclerosis
    • Sørensen TL, Sellebjerg F, Jensen CV, Strieter RM, Ransohoff RM. Chemokines CXCL10 and CCL2. differential involvement in intrathecal inflammation in multiple sclerosis. Eur J Neurol 8: 665-672, 2001.
    • (2001) Eur J Neurol , vol.8 , pp. 665-672
    • Sørensen, T.L.1    Sellebjerg, F.2    Jensen, C.V.3    Strieter, R.M.4    Ransohoff, R.M.5
  • 34
    • 0035795017 scopus 로고    scopus 로고
    • Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies
    • Franciotta D, Martino G, Zardini E, et al. Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies. J Neuroimmunol 115: 192-198, 2001.
    • (2001) J Neuroimmunol , vol.115 , pp. 192-198
    • Franciotta, D.1    Martino, G.2    Zardini, E.3
  • 35
    • 0036214230 scopus 로고    scopus 로고
    • Expression of chemokines in the CSF and correlation with clinical disease activity in patients with multiple sclerosis
    • Mahad DJ, Howell SJL, Woodroofe MN. Expression of chemokines in the CSF and correlation with clinical disease activity in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 72: 498-502, 2002.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 498-502
    • Mahad, D.J.1    Howell, S.J.L.2    Woodroofe, M.N.3
  • 36
    • 33749830743 scopus 로고    scopus 로고
    • Elevated CSF free kappa light chains correlate with disability prognosis in multiple sclerosis
    • Rinker JR, Trinkaus K, Cross AH. Elevated CSF free kappa light chains correlate with disability prognosis in multiple sclerosis. Neurology 67: 1288-1290, 2006.
    • (2006) Neurology , vol.67 , pp. 1288-1290
    • Rinker, J.R.1    Trinkaus, K.2    Cross, A.H.3
  • 37
    • 0036229882 scopus 로고    scopus 로고
    • Immunological disturbances in the central nervous system linked to MRI findings in multiple sclerosis
    • Wang H-Y, Matsui M, Saida T. Immunological disturbances in the central nervous system linked to MRI findings in multiple sclerosis. J Neuroimmunol 125: 149-154, 2002.
    • (2002) J Neuroimmunol , vol.125 , pp. 149-154
    • Wang, H.-Y.1    Matsui, M.2    Saida, T.3
  • 38
    • 23944448666 scopus 로고    scopus 로고
    • Differences in systemic and central nervous system cellular immunity relevant to relapsing-remitting multiple sclerosis
    • Matsui M, Araya S, Wang HY, Matsushima K, Saida T. Differences in systemic and central nervous system cellular immunity relevant to relapsing-remitting multiple sclerosis. J Neurol 252: 908-915, 2005.
    • (2005) J Neurol , vol.252 , pp. 908-915
    • Matsui, M.1    Araya, S.2    Wang, H.Y.3    Matsushima, K.4    Saida, T.5
  • 39
    • 77950876430 scopus 로고    scopus 로고
    • Clinical effect of neutralizing antibodies to interferon beta that persist long after cessation of therapy for multiple sclerosis
    • van der Voort LF, Gilli F, Bertolotto A, et al. Clinical effect of neutralizing antibodies to interferon beta that persist long after cessation of therapy for multiple sclerosis. Arch Neurol 67: 402-407, 2010.
    • (2010) Arch Neurol , vol.67 , pp. 402-407
    • van der Voort, L.F.1    Gilli, F.2    Bertolotto, A.3
  • 40
    • 84857043047 scopus 로고    scopus 로고
    • CD49d expression as a promising biomarker to monitor natalizumab efficacy
    • Defer G, Mariotte D, Derache N, et al. CD49d expression as a promising biomarker to monitor natalizumab efficacy. J Neurol Sci 314: 138-142, 2012.
    • (2012) J Neurol Sci , vol.314 , pp. 138-142
    • Defer, G.1    Mariotte, D.2    Derache, N.3
  • 41
    • 70349741303 scopus 로고    scopus 로고
    • Interferon-beta-1a treatment increases CD56bright natural killer cells and CD4+CD25+ Foxp3 expression in subsets with multiple sclerosis
    • Vandenbark AA, Huan J, Agotsch M, et al. Interferon-beta-1a treatment increases CD56bright natural killer cells and CD4+CD25+ Foxp3 expression in subsets with multiple sclerosis. J Neuroimmunol 215: 125-128, 2009.
    • (2009) J Neuroimmunol , vol.215 , pp. 125-128
    • Vandenbark, A.A.1    Huan, J.2    Agotsch, M.3
  • 42
    • 73149090090 scopus 로고    scopus 로고
    • + regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): A preliminary study
    • Namdar A, Nikbin B, Ghabaee M, Bayati A, Izad M. Effect of IFN-β therapy on the frequency and function of CD4+CD25+ regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study. J Neuroimmunol 218: 120-124, 2010.
    • (2010) J Neuroimmunol , vol.218 , pp. 120-124
    • Namdar, A.1    Nikbin, B.2    Ghabaee, M.3    Bayati, A.4    Izad, M.5
  • 43
    • 11144297111 scopus 로고    scopus 로고
    • Biological markers in CSF and blood for axonal degeneration in multiple sclerosis
    • Teunissen C, Dijkstra C, Polman C. Biological markers in CSF and blood for axonal degeneration in multiple sclerosis. Lancet Neurol 4: 32-41, 2005.
    • (2005) Lancet Neurol , vol.4 , pp. 32-41
    • Teunissen, C.1    Dijkstra, C.2    Polman, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.