Dexamethasone for acute asthma exacerbations in children: A meta-analysis

Pediatrics

Volumn 133, Issue 3, 2014, Pages 493-499

  Keeney, Grant E ^a   Gray, Matthew P ^a   Morrison, Andrea K ^a   Levas, Michael N ^a   Kessler, Elizabeth A ^a   Hill, Garick D ^a   Gorelick, Marc H ^a   Jackson, Jeffrey L ^a,b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Asthma; Dexamethasone; Prednisolone; Prednisone; Status asthmaticus

Indexed keywords

DEXAMETHASONE; PREDNISOLONE; PREDNISONE;

ASTHMA; ASTHMATIC STATE; CHILD; CHILD HEALTH CARE; CONSULTATION; DISEASE EXACERBATION; DISEASE PREDISPOSITION; DRUG EFFICACY; EMERGENCY WARD; FEMALE; HOSPITAL READMISSION; HUMAN; MALE; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; REVIEW; RISK FACTOR; SINGLE DRUG DOSE; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT OUTCOME; VOMITING;

ASTHMA; DEXAMETHASONE; PREDNISOLONE; PREDNISONE; STATUS ASTHMATICUS;

ACUTE DISEASE; ANTI-INFLAMMATORY AGENTS; ASTHMA; CHILD; CLINICAL TRIALS AS TOPIC; DEXAMETHASONE; HUMANS;

EID: 84895171522     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2013-2273     Document Type: Review

References (19)

1. National Asthma Education and Prevention Program. Expert panel report 3 (EPR-3): Guidelines for the diagnosis and management of asthma-summary report 2007. J Allergy Clin Immunol. 2007;120(suppl 5):S94-S138
2. Scarfone RJ, Friedlaender E. Corticosteroids in acute asthma: past, present, and future. Pediatr Emerg Care. 2003;19(5):355-361
3. Akinbami LJ, Moorman JE, Garbe PL, Sondik EJ. Status of childhood asthma in the United States, 1980 -2007. Pediatrics. 2009;123(suppl 3):S131-S145
4. Papadopoulos NG, Arakawa H, Carlsen KH, et al. International consensus on (ICON) pediatric asthma. Allergy. 2012;67(8):976-997
5. Higgins J, Altman D, Sterne A. Chapter 8: Assessing risk of bias in included studies. In: Higgings J, Green S, eds. Cochrane handbook for systematic reviews of interventions, version 5.1.0 [updated March 2011]. The Cochrane Collaboration; 2011. Available at: www.cochrane-handbook.org. Accessed May 12, 2013
6. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials . 1996;17(1):1-12 (Pubitemid 26120810)
7. Sharp S. Meta-analysis regression. Stata Tech Bull. 1998;42:16-22
8. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-560 (Pubitemid 37088507)
9. Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Comparison of two methods to detect publication bias in meta-analysis. JAMA . 2006;295(6):676-680 (Pubitemid 43209069)
10. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629 -634
11. Altamimi S, Robertson G, Jastaniah W, et al. Single-dose oral dexamethasone in the emergency management of children with exacerbations of mild to moderate asthma. Pediatr Emerg Care. 2006;22(12):786-793 (Pubitemid 46049740)
12. Gordon S, Tompkins T, Dayan PS. Randomized trial of single-dose intramuscular dexamethasone compared with prednisolone for children with acute asthma. Pediatr Emerg Care. 2007;23(8):521-527 (Pubitemid 47339791)
13. Greenberg RA, Kerby G, Roosevelt GE. A comparison of oral dexamethasone with oral prednisone in pediatric asthma exacerbations treated in the emergency department. Clin Pediatr (Phila). 2008;47(8):817-823
14. Gries DM, Moffitt DR, Pulos E, Carter ER. A single dose of intramuscularly administered dexamethasone acetate is as effective as oral prednisone to treat asthma exacerbations in young children. J Pediatr. 2000;136(3):298 -303
15. Klig JE, Hodge D III, Rutherford MW. Symptomatic improvement following emergency department management of asthma: a pilot study of intramuscular dexamethasone versus oral prednisone. J Asthma. 1997;34(5):419-425 (Pubitemid 27462550)
16. Qureshi F, Zaritsky A, Poirier MP. Comparative efficacy of oral dexamethasone versus oral prednisone in acute pediatric asthma. J Pediatr. 2001;139(1):20-26 (Pubitemid 32613982)
17. Chang AB, Clark R, Sloots TP, et al. A 5- versus 3-day course of oral corticosteroids for children with asthma exacerbations who are not hospitalised: a randomised controlled trial. Med J Aust. 2008;189(6):306-310
18. Kim MK, Yen K, Redman RL, Nelson TJ, Brandos J, Hennes HM. Vomiting of liquid corticosteroids in children with asthma. Pediatr Emerg Care. 2006;22(6):397-401 (Pubitemid 43995317)
19. Mitchell JC, Counselman FL. A taste comparison of three different liquid steroid preparations: prednisone, prednisolone, and dexamethasone. Acad Emerg Med. 2003;10(4):400-403 (Pubitemid 36437803)