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Volumn 729, Issue 1, 2014, Pages 107-115

1,2,3,4-Tetrahydroisoquinoline produces an antidepressant-like effect in the forced swim test and chronic mild stress model of depression in the rat: Neurochemical correlates

Author keywords

1,2,3,4 Tetrahydroisoquinoline; Chronic mild stress; Forced swimming test; Imipramine; Metabolism of monoamines; Models of depression; Rat brain

Indexed keywords

3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; 4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; 5 HYDROXYINDOLEACETIC ACID; DOPAMINE; HOMOVANILLIC ACID; IMIPRAMINE; NORADRENALIN; TETRAHYDROISOQUINOLINE; ANTIDEPRESSANT AGENT; TETRAHYDROISOQUINOLINE DERIVATIVE;

EID: 84895168057     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.01.075     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 0032714389 scopus 로고    scopus 로고
    • Differential changes in brain and platelet 5-HT concentrations after steady-state achievement and repeated administration of antidepressant drugs in mice
    • J.C. Alvarez, M. Sanceaume, C. Advenier, and O. Spreux-Varoquaux Differential changes in brain and platelet 5-HT concentrations after steady-state achievement and repeated administration of antidepressant drugs in mice Eur. Neuropsychopharmacol. 10 1999 31 36
    • (1999) Eur. Neuropsychopharmacol. , vol.10 , pp. 31-36
    • Alvarez, J.C.1    Sanceaume, M.2    Advenier, C.3    Spreux-Varoquaux, O.4
  • 2
    • 0343503019 scopus 로고    scopus 로고
    • Neurochemical changes induced by acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain
    • DOI 10.1016/S0306-4522(99)00533-3, PII S0306452299005333
    • L. Antkiewicz-Michaluk, I. Romańska, I. Papla, J. Michaluk, M. Bakalarz, J. Vetulani, A. Krygowska-Wajs, and A. Szczudlik Neurochemical changes induced by acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain Neuroscience 96 2000 59 64 (Pubitemid 30103603)
    • (2000) Neuroscience , vol.96 , Issue.1 , pp. 59-64
    • Antkiewicz-Michaluk, L.1    Romanska, I.2    Papla, I.3    Michaluk, J.4    Bakalarz, M.5    Vetulani, J.6    Krygowska-Wajs, A.7    Szczudlik, A.8
  • 3
    • 0034932971 scopus 로고    scopus 로고
    • Different action on dopamine catabolic pathways of two endogenous 1,2,3,4-tetrahydroisoquinolines with similar antidopaminergic properties
    • DOI 10.1046/j.1471-4159.2001.00391.x
    • L. Antkiewicz-Michaluk, J. Michaluk, M. Mokrosz, I. Romańska, E. Lorenc-Koci, S. Otha, and J. Vetulani Different action on dopamine catabolic pathways of two endogenous 1,2,3,4-tetrahydroisoquinolines with similar antidopaminergic properties J. Neurochem. 78 2001 100 108 (Pubitemid 32622592)
    • (2001) Journal of Neurochemistry , vol.78 , Issue.1 , pp. 100-108
    • Antkiewicz-Michaluk, L.1    Michaluk, J.2    Mokrosz, M.3    Romanska, I.4    Lorenc-Koci, E.5    Ohta, S.6    Vetulani, J.7
  • 4
    • 33645867358 scopus 로고    scopus 로고
    • The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: The importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity
    • L. Antkiewicz-Michaluk, J.W. Łazarewicz, A. Patsenka, M. Kajta, E. Ziemińska, E. Salińska, A. Wa̧sik, K. Gołembiowska, and J. Vetulani The mechanism of 1,2,3,4-tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate-induced excitotoxicity J. Neurochem. 97 2006 846 856
    • (2006) J. Neurochem. , vol.97 , pp. 846-856
    • Antkiewicz-Michaluk, L.1    Łazarewicz, J.W.2    Patsenka, A.3    Kajta, M.4    Ziemińska, E.5    Salińska, E.6    Wa̧sik, A.7    Gołembiowska, K.8    Vetulani, J.9
  • 5
    • 0029067853 scopus 로고
    • Role of the serotonergic system in the forced swimming test
    • F. Borsini Role of the serotonergic system in the forced swimming test Neurosci. Biobehav. Rev. 19 1995 377 395
    • (1995) Neurosci. Biobehav. Rev. , vol.19 , pp. 377-395
    • Borsini, F.1
  • 6
    • 0023915698 scopus 로고
    • Is the forced swimming test a suitable model for revealing antidepressant activity?
    • F. Borsini, and A. Meli Is the forced swimming test a suitable model for revealing antidepressant activity? Psychopharmacology 94 1988 147 160 (Pubitemid 18040687)
    • (1988) Psychopharmacology , vol.94 , Issue.2 , pp. 147-160
    • Borsini, F.1    Meli, A.2
  • 7
    • 26844507945 scopus 로고    scopus 로고
    • Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment
    • DOI 10.1007/s00213-005-0093-5
    • J.F. Cryan, M.E. Page, and I. Lucki Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment Psychopharmacology 182 2005 335 344 (Pubitemid 41464645)
    • (2005) Psychopharmacology , vol.182 , Issue.3 , pp. 335-344
    • Cryan, J.F.1    Page, M.E.2    Lucki, I.3
  • 8
    • 0029081299 scopus 로고
    • Active behaviors in the rat forced swimming test differentially produced by serotoninergic and noradrenergic antidepressants
    • M.J. Detke, M. Rickels, and I. Lucki Active behaviors in the rat forced swimming test differentially produced by serotoninergic and noradrenergic antidepressants Psychopharmacology (Berlin) 121 1995 66 72
    • (1995) Psychopharmacology (Berlin) , vol.121 , pp. 66-72
    • Detke, M.J.1    Rickels, M.2    Lucki, I.3
  • 9
    • 0018368924 scopus 로고
    • Inhibition of neuronal uptake of 3H-biogenic amines rat cerebral cortex by partially and fully saturated derivatives of imipramine and desipramine.The importance of the aromatic ring in adrenergic amines - Part 3
    • G.L. Grunewald, T.J. Reitz, J.A. Ruth, S. Vollmer, L.E. Eiden, and C.O. Ruthedge Inhibition of neuronal uptake of 3H-biogenic amines rat cerebral cortex by partially and fully saturated derivatives of imipramine and desipramine. The importance of the aromatic ring in adrenergic amines - Part 3 Biochem. Pharmacol. 28 1979 417 421
    • (1979) Biochem. Pharmacol. , vol.28 , pp. 417-421
    • Grunewald, G.L.1    Reitz, T.J.2    Ruth, J.A.3    Vollmer, S.4    Eiden, L.E.5    Ruthedge, C.O.6
  • 11
    • 0018414674 scopus 로고
    • Inhibition of biogenic amines uptake by imipramine, desipramine, 2 OH-imipramine and 2 OH-desipramine in rat brain
    • J.I. Javaid, J.M. Perel, and J.M. Davis Inhibition of biogenic amines uptake by imipramine, desipramine, 2 OH-imipramine and 2 OH-desipramine in rat brain Life Sci. 24 1979 21 28 (Pubitemid 9107782)
    • (1979) Life Sciences , vol.24 , Issue.1 , pp. 21-28
    • Javaid, J.I.1    Perel, J.M.2    Davis, J.M.3
  • 12
    • 0030424363 scopus 로고    scopus 로고
    • Blockade of the serotonin and norepinephrine uptake processes by duloxetine: In vitro and in vivo studies in the rat brain
    • K. Kasamo, P. Blier, and C. De Montigny Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain Neurobiol. Psych., Canada 277 1996 278 286 (Pubitemid 27169071)
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.277 , Issue.1 , pp. 278-286
    • Kasamo, K.1    Blier, P.2    De Montigny, C.3
  • 15
    • 0023011644 scopus 로고
    • Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain
    • DOI 10.1016/0006-291X(86)91111-3
    • M. Kohno, S. Otha, and M. Hirobe Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain Biochem. Biophys. Res. Commun. 140 1986 448 454 (Pubitemid 17190044)
    • (1986) Biochemical and Biophysical Research Communications , vol.140 , Issue.1 , pp. 448-454
    • Kohno, M.1    Ohta, S.2    Hirobe, M.3
  • 16
    • 0025978617 scopus 로고
    • Deamination of norepinephrine, dopamine, and serotonin by type A monoamine oxidase in discrete regions of the rat brain and inhibition by RS-8359
    • Y. Kumagae, Y. Matsui, and N. Iwata Deamination of norepinephrine, dopamine, and serotonin by type A monoamine oxidase in discrete regions of the rat brain and inhibition by RS-8359 Jpn. J. Pharmacol. 55 1991 121 128
    • (1991) Jpn. J. Pharmacol. , vol.55 , pp. 121-128
    • Kumagae, Y.1    Matsui, Y.2    Iwata, N.3
  • 18
    • 0033631519 scopus 로고    scopus 로고
    • Effect of acute and chronic administration of 1,2,3,4- tetrahydroisoquinoline on muscle tone, metabolism of dopamine in the striatum and tyrosine hydroxylase immunocytochemistry in the substantia nigra, in rats
    • DOI 10.1016/S0306-4522(99)00511-4, PII S0306452299005114
    • E. Lorenc-Koci, M. Śmiałowska, L. Antkiewicz-Michaluk, K. Gołembiowska, M. Bajkowska, and S. Wolfarth Effect of acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline on muscle tone, metabolism of dopamine in the striatum and tyrosine hydroxylase immunocytochemistry in the substantia nigra, in rats Neuroscience 95 2000 1049 1059 (Pubitemid 30006893)
    • (1999) Neuroscience , vol.95 , Issue.4 , pp. 1049-1059
    • Lorenc-Koci, E.1    Smialowska, M.2    Antkiewicz-Michaluk, L.3    Golembiowska, K.4    Bajkowska, M.5    Wolfarth, S.6
  • 19
    • 22144438127 scopus 로고    scopus 로고
    • Treatment with 1,2,3,4-tetrahydroisoquinolone affects the levels of nitric oxide, S-nitrosothiols, glutathione and the enzymatic activity of γ-glutamyl transpeptidase in the dopaminergic structures of rat brain
    • DOI 10.1016/j.brainres.2005.04.039, PII S0006899305006025
    • E. Lorenc-Koci, M. Sokołowska, I. Kwiecień, and L. Włodek Treatment with 1,2,3,4-tetrahydroisoquinoline affects the levels of nitric oxide, S-nitrosothiols, glutathione and the enzymatic activity of gamma-glutamyl transpeptidase in the dopaminergic structures of rat brain Brain Res. 1049 2005 133 146 (Pubitemid 41072929)
    • (2005) Brain Research , vol.1049 , Issue.2 , pp. 133-146
    • Lorenc-Koci, E.1    Sokolowska, M.2    Kwiecien, I.3    Wlodek, L.4
  • 20
    • 48049084135 scopus 로고    scopus 로고
    • The cytokine hypothesis of depression: Inflammation, oxidative and nitrosative stress and leaky gut as a new target for adjunctive treatments in depression
    • M. Maes The cytokine hypothesis of depression: inflammation, oxidative and nitrosative stress and leaky gut as a new target for adjunctive treatments in depression Neuro. Endocrinol. Lett. 29 2008 287 291
    • (2008) Neuro. Endocrinol. Lett. , vol.29 , pp. 287-291
    • Maes, M.1
  • 21
    • 79954568978 scopus 로고    scopus 로고
    • A review on the oxidative and nitrosative stress pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness
    • M. Maes, P. Galecki, Y.S. Chang, and M. Berk A review on the oxidative and nitrosative stress pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness Prog. Neuro-Psychopharmacol. Biol. Psychiatry 35 2011 676 692
    • (2011) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.35 , pp. 676-692
    • Maes, M.1    Galecki, P.2    Chang, Y.S.3    Berk, M.4
  • 22
    • 0034130574 scopus 로고    scopus 로고
    • Psychiatric morbidity and comorbidity following accidental man-made traumatic events: Incidence and risk factors
    • M. Maes, J. Mylle, L. Delmeire, and C. Altamura Psychiatric morbidity and comorbidity following accidental man-made traumatic events: incidence and risk factors Eur. Arch. Psychiatry Clin. Neurosci. 250 2000 156 162 (Pubitemid 30417216)
    • (2000) European Archives of Psychiatry and Clinical Neuroscience , vol.250 , Issue.3 , pp. 156-162
    • Maes, M.1    Mylle, J.2    Delmeire, L.3    Altamura, C.4
  • 23
  • 24
    • 0023894885 scopus 로고
    • Presence of tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline in foods: Compounds related to Parkinson×s disease
    • Y. Makino, S. Ohta, O. Tachikawa, and M. Hirobe Presence of tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline in foods: compounds related to Parkinson×s disease Life Sci. 43 1988 373 378
    • (1988) Life Sci. , vol.43 , pp. 373-378
    • Makino, Y.1    Ohta, S.2    Tachikawa, O.3    Hirobe, M.4
  • 25
    • 0027420818 scopus 로고
    • Naturally-occurring isoquinolines perturb monoamine metabolism in the brain: Studied by in vivo microdialysis
    • DOI 10.1007/BF01245003
    • W. Maruyama, D. Nakahara, P. Dostert, and A. Takahashi Naturally-occurring isoquinolines perturb monoamine metabolism in the brain: studied by in vivo microdialysis J. Neural. Transm. Gen. Sect. 94 1993 91 102 (Pubitemid 23345518)
    • (1993) Journal of Neural Transmission - General Section , vol.94 , Issue.2 , pp. 91-102
    • Maruyama, W.1    Nakahara, D.2    Dostert, P.3    Takahashi, A.4    Naoi, M.5
  • 26
    • 0036205584 scopus 로고    scopus 로고
    • Role of noradrenergic system in the mechanism of action of endogenous neurotoxin 1,2,3,4-tetrahydroisoquinoline: Biochemical and functional studies
    • J. Michaluk, A. Krygowska-Wajs, B. Karolewicz, and L. Antkiewicz-Michaluk Role of noradrenergic system In the mechanism of action of endogenous neurotoxin 1,2,3,4-tetrahydroisoquinoline: biochemical and functional studies Pol. J. Pharmacol. 54 2002 19 25 (Pubitemid 34269619)
    • (2002) Polish Journal of Pharmacology , vol.54 , Issue.1 , pp. 19-25
    • Michaluk, J.1    Krygowska-Wajs, A.2    Karolewicz, B.3    Antkiewicz-Michaluk, L.4
  • 27
    • 0030065277 scopus 로고    scopus 로고
    • Effects of moclobemide on forced-swimming stress and brain monoamine levels in mice
    • DOI 10.1016/0091-3057(95)02019-5
    • H. Miura, M. Naoi, D. Nakahara, T. Ohta, and T. Nagatsu Effects of moclobemide on forced-swimming stress and brain monoamine levels in mice Pharmacol. Biochem. Behav. 53 1996 469 475 (Pubitemid 26059209)
    • (1996) Pharmacology Biochemistry and Behavior , vol.53 , Issue.2 , pp. 469-475
    • Miura, H.1    Naoi, M.2    Nakahara, D.3    Ohta, T.4    Nagatsu, T.5
  • 28
    • 39649105423 scopus 로고    scopus 로고
    • Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviors in mice
    • F. Murray, D.W. Smith, and P.H. Huston Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviors in mice Eur. J. Pharmacol. 583 2008 115 127
    • (2008) Eur. J. Pharmacol. , vol.583 , pp. 115-127
    • Murray, F.1    Smith, D.W.2    Huston, P.H.3
  • 30
    • 14244249957 scopus 로고    scopus 로고
    • Inhibition of rodent brain monoamine oxidase and tyrosine hydroxylase by endogenous compounds - 1,2,3,4-tetrahydroisoquinoline alkaloids
    • A. Patsenka, and L. Antkiewicz-Michaluk Inhibition of rodent brain monoamine oxidase and tyrosine hydroxylase by endogenous compounds - 1,2,3,4-tetrahydro-isoquinoline alkaloids Pol. J. Pharmacol. 56 2004 727 734 (Pubitemid 40287474)
    • (2004) Polish Journal of Pharmacology , vol.56 , Issue.6 , pp. 727-734
    • Patsenka, A.1    Antkiewicz-Michaluk, L.2
  • 31
    • 0018268297 scopus 로고
    • Behavioural despair test in rats: A new model sensitive to antidepressant treatments
    • R.D. Porsolt, G. Anton, N. Blavet, and M. Jalfre Behavioural despair test in rats: a new model sensitive to antidepressant treatments Eur. J. Pharmacol. 47 1978 379 391
    • (1978) Eur. J. Pharmacol. , vol.47 , pp. 379-391
    • Porsolt, R.D.1    Anton, G.2    Blavet, N.3    Jalfre, M.4
  • 32
    • 0031931974 scopus 로고    scopus 로고
    • Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test
    • DOI 10.1007/s002130050555
    • J.P. Reneric, and I. Lucki Antidepressant behavioral effects by inhibition of monoamine re-uptake in the rat forced swimming test Psychopharmacology 136 1998 190 197 (Pubitemid 28137959)
    • (1998) Psychopharmacology , vol.136 , Issue.2 , pp. 190-197
    • Reneric, J.-P.1    Lucki, I.2
  • 33
    • 0028099484 scopus 로고
    • Pharmacology of antidepressants - Characteristics of the ideal drug
    • E. Richelson Pharmacology of antidepressants - characteristics of the ideal drug Mayo Clin. Proc. 69 1994 1069 1081 (Pubitemid 24346991)
    • (1994) Mayo Clinic Proceedings , vol.69 , Issue.11 , pp. 1069-1081
    • Richelson, E.1
  • 34
    • 0034730476 scopus 로고    scopus 로고
    • Antidepressants: Past, present and future
    • J. Vetulani, and I. Nalepa Antidepressants: past, present and future Eur. J. Pharmacol. 405 2000 351 363
    • (2000) Eur. J. Pharmacol. , vol.405 , pp. 351-363
    • Vetulani, J.1    Nalepa, I.2
  • 35
    • 84872906805 scopus 로고    scopus 로고
    • Antidepressant-like activity of the endogenous amine, 1-methyl-1,2,3,4-tetrahydroisoquinoline in the behavioral despair test in the rat, and its neurochemical correlates: A comparison with the classical antidepressant, imipramine
    • A. Wa̧sik, E. Mozdzeń, I. Romańska, J. Michaluk, and L. Antkiewicz-Michaluk Antidepressant-like activity of the endogenous amine, 1-methyl-1,2,3,4-tetrahydroisoquinoline in the behavioral despair test in the rat, and its neurochemical correlates: a comparison with the classical antidepressant, imipramine Eur. J. Pharmacol. 700 2013 110 117
    • (2013) Eur. J. Pharmacol. , vol.700 , pp. 110-117
    • Wa̧sik, A.1    Mozdzeń, E.2    Romańska, I.3    Michaluk, J.4    Antkiewicz-Michaluk, L.5
  • 36
    • 0025057433 scopus 로고
    • Animal model of depression: An overview
    • P. Willner Animal model of depression: an overview Pharmacol. Ther. 45 1990 425 455
    • (1990) Pharmacol. Ther. , vol.45 , pp. 425-455
    • Willner, P.1
  • 37
    • 0031440325 scopus 로고    scopus 로고
    • Validity, reliability and utility of the chronic mild stress model of depression: A 10-year review and evaluation
    • DOI 10.1007/s002130050456
    • P. Willner Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation (Review) Psychopharmacology 134 1997 319 329 (Pubitemid 28023396)
    • (1997) Psychopharmacology , vol.134 , Issue.4 , pp. 319-329
    • Willner, P.1
  • 38
    • 23844500078 scopus 로고    scopus 로고
    • Chronic mild stress (CMS) revisited: Consistency and behavioural- neurobiological concordance in the effects of CMS
    • DOI 10.1159/000087097
    • P. Willner Chronic mild stress (CMS) revisited: consistency and behavioral-neurobiological concordance in the effects of CMS Neuropsychobiology 52 2005 90 110 (Pubitemid 41160326)
    • (2005) Neuropsychobiology , vol.52 , Issue.2 , pp. 90-110
    • Willner, P.1
  • 39
    • 0026440178 scopus 로고
    • Chronic mild stress-induced anhedonia: A realistic animal model of depression
    • P. Willner, R. Muscat, and M. Papp Chronic mild stress-induced anhedonia: a realistic animal model of depression Neurosci. Biobehav. Rev. 16 1992 525 534
    • (1992) Neurosci. Biobehav. Rev. , vol.16 , pp. 525-534
    • Willner, P.1    Muscat, R.2    Papp, M.3
  • 40
    • 0032749525 scopus 로고    scopus 로고
    • Regional distribution of parkinsonism-preventing endogenous tetrahydroisoquinoline derivatives and an endogenous parkinsonism-preventing substance-synthesizing enzyme in monkey brain
    • DOI 10.1016/S0304-3940(99)00786-7, PII S0304394099007867
    • T. Yamakawa, Y. Kotake, M. Fujitani, H. Shintani, Y. Makino, and S. Ohta Regional distribution of parkinsonism-preventing endogenous tetrahydroisoquinoline derivatives and an endogenous parkinsonism-preventing substance-synthesizing enzyme in monkey brain Neurosci. Lett. 276 1999 68 70 (Pubitemid 29525527)
    • (1999) Neuroscience Letters , vol.276 , Issue.1 , pp. 68-70
    • Yamakawa, T.1    Kotake, Y.2    Fujitani, M.3    Shintani, H.4    Makino, Y.5    Ohta, S.6
  • 41
    • 30444437749 scopus 로고    scopus 로고
    • Monoamine oxidase: Isoforms and inhibitors in Parkinson×s disease and depressive illness
    • M.B. Youdim, and Y.S. Bakhle Monoamine oxidase: isoforms and inhibitors in Parkinson×s disease and depressive illness Brit. J. Pharmacol. 147 2006 287 296
    • (2006) Brit. J. Pharmacol. , vol.147 , pp. 287-296
    • Youdim, M.B.1    Bakhle, Y.S.2
  • 42
    • 33645307953 scopus 로고    scopus 로고
    • The therapeutic potential of monoamine oxidase inhibitors
    • M.B. Youdim, D. Edmondson, and K.F. Tipton The therapeutic potential of monoamine oxidase inhibitors Nat. Rev. Neurosci. 7 2006 295 309
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 295-309
    • Youdim, M.B.1    Edmondson, D.2    Tipton, K.F.3
  • 43
    • 3242741013 scopus 로고    scopus 로고
    • Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders
    • J.Z. Zhang Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders Life Sci. 75 2004 1659 1699
    • (2004) Life Sci. , vol.75 , pp. 1659-1699
    • Zhang, J.Z.1
  • 44
    • 38549098646 scopus 로고    scopus 로고
    • A mouse model of depression induced by repeated corticosterone injections
    • Y. Zhao, R. Ma, J. Shen, H. Su, D. Xing, and L. Du A mouse model of depression induced by repeated corticosterone injections Eur. J. Pharmacol. 581 2008 113 120
    • (2008) Eur. J. Pharmacol. , vol.581 , pp. 113-120
    • Zhao, Y.1    Ma, R.2    Shen, J.3    Su, H.4    Xing, D.5    Du, L.6


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