Anti-inflammatory and anti-arthritic effects of 3-hydroxy, 2-methoxy sodium butanoate from the leaves of Clerodendrum phlomidis L.f.

Inflammation Research

Volumn 63, Issue 2, 2014, Pages 127-138

  Prakash Babu, N ^a   Saravanan, S ^a   Pandikumar, P ^a   Bala Krishna, K ^a   Karunai Raj, M ^a,b   Ignacimuthu, S ^a  

^a LOYOLA COLLEGE   (India)

^b Orchid Chemicals and Pharmaceuticals Ltd   (India)

Author keywords

3 Hydroxy,2 methoxy sodium butanoate; Anti arthritic; Anti inflammatory; Bioactivity guided fractionation; Clerodendrum phlomidis

Indexed keywords

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; BUTYRATES; CARRAGEENAN; CLERODENDRUM; CYTOKINES; EDEMA; FEMALE; FOOT JOINTS; INDIA; MEDICINE, EAST ASIAN TRADITIONAL; NEUTROPHILS; PEROXIDASE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 84895077089     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-013-0681-5     Document Type: Article

References (54)

1. Yeom MJ, Lee HC, Kim GH, Lee HJ, Shim I, Oh SK, Kang SK, Hahm DH. Anti-arthritic effects of Ephedra sinica STAPF herb-acupuncture: inhibition of lipopolysaccharide-induced inflammation and adjuvant-induced polyarthritis. J Pharmacol Sci. 2006;100:41-50. (Pubitemid 43161613)
2. Lee S-J, Nam W-D, Na H-J, Cho Y-L, Ha K-S, Hwang J-Y, Lee H, Kim S-O, Kwon Y-G, Kim Y-M. CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kB activation. Biochem Pharmacol. 2008;76:79-90.
3. Feldmann M, Brennan FM, Maini RN. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol. 1996;14:397-440. (Pubitemid 26130190)
4. Mythilypriya R, Shanthi P, Sachdanandam P. Therapeutic effect of Kalpaamruthaa, a herbal preparation on adjuvant induced arthritis in wistar rats. Inflammopharmacology. 2008;16:21-35. (Pubitemid 351226000)
5. Adou E, Miller JS, Ratovoson F, Birkinshaw C, Andriantsiferana R, Rasamison VE, Kingston DG. Antiproliferative cardenolides from Pentopetia androsaemifolia Decne. from the Madagascar rain forest. Indian J Exp Biol. 2010;48:248-257.
6. Balandrin NF, Kingkorn AD, Farnsworth NR. In: Balandrin AD, Kingkorn MF, editors. Human medicinal agents from plants. ACS Symposium Series, vol. 534. 1993; pp. 2-12.
7. Matthew KM (1991) An excursion flora of Central Tamilnadu, India. Oxford-IBH, New Delhi
8. Anonymous. The Ayurvedic pharmacopoeia of India. Part 1 (vol. III). Government of India; 2001. pp. 3-4.
9. Katewa SS, Chaudhary BL, Jain A. Folk herbal medicines from tribal area of Rajasthan. India J Ethnopharmacol. 2004;92:41-46. (Pubitemid 38514753)
10. Kirtikar KR, Basu BD. An ICS. Indian medicinal plants, vol. 3. Dehradun: Bishen Singh Mahendra Pal Singh; 1975. p. 1947-1948.
11. Patil MV, Patil DA. Ethnobotany of Nasik District, Maharashtra. New Delhi: Daya books; 2006. p. 112.
12. Nadkarni AK. Indian Materia Medica, I. Bombay: Popular Book Department; 1954.
13. Anis M, Sharma MP, Iqbal M. Herbal ethnomedicine of the Qualior forest division in Madhya Pradesh. India. Pharm Biol. 2000;38:241-253.
14. Pandikumar P, Chellappandian M, Mutheeswaran S, Ignacimuthu S. Consensus of local knowledge on medicinal plants among traditional healers in Mayiladumparai block of Theni District, Tamil Nadu. India J Ethnopharmacol. 2011;134:354-362.
15. Babu NP, Pandikumar P, Ignacimuthu S. Lysosomal membrane stabilization and anti-inflammatory activity of Clerodendrum phlomidis L.f., a traditional medicinal plant. J Ethnopharmacol. 2011;135:779-785.
16. Winter CA, Risley EA, Nuss GW. Carrageenan-induced edema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc soc Exp Biol. 1962;111:544-547.
17. King J. The phosphohydrolases-acid and alkaline phosphatases. In: Van D, editor. Practical clinical enzymology. London: Nostrand; 1965. pp. 191-208.
18. Delvin E, Gianetto R. The purification of lysosomal rat liver β-glucuronidase. Biochem Biophy Acta. 1970;220:93-100.
19. Rosenblit PD, Metzyer PP, Wick AN. Effect of streptozotocin diabetes on acid phosphatase and selected glycosidase activities of serum and various rat organs. Proc Soc Exp Biol Med. 1974;145:244-247.
20. Sapolsky AI, Altman RD, Howell DS. Cathepsin-D activity in normal and osteoarthritic human cartilage. Fed Proc. 1973;32:1489-1493.
21. Niebes P. Determination of enzymes and degradation products of glycosaminoglycan metabolism in the serum of healthy and varicose subjects. Clin Chim Acta. 1972;42:399-408.
22. Wagner WD. More sensitive assay discriminating galactosamine and glucosamine in mixtures. Ann Biochem. 1979;94:394-397. (Pubitemid 9173030)
23. Warren L. The thiobarbituric acid assay of sialic acid. J Biol Chem. 1959;234:1971-1975.
24. Bitter T, Muir HM. Modified uronic acid-carbazole reaction. Ann Biochem. 1962;4:330-334.
25. Hansson LO, Lindquist L. C-reactive protein: its role in the diagnosis and follow-up of infectious diseases. Curr Opin Infec Dis. 1997;10:196-201. (Pubitemid 27281483)
26. Ravin JA. Improved colorimetric enzymatic assay of ceruloplasmin. J Lab Clin Med. 1961;58:161-168.
27. Lempert H. Determination of plasma protein. In: Varley H, editor. Practical Clinical Biochemistry. New Delhi: CBS; 1969.
28. Newman SL, Henson JE, Henson PM. Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J Exp Med. 1982;156:430-442. (Pubitemid 12041405)
29. Gutteridge JMC. Ferrous-salt-promoted damage to deoxyribose and benzoate: the increased effectiveness of hydroxyl-radical scavengers in the presence of EDTA. Biochem J. 1987;243:709-714.
30. Nishikimi M, Appaji N, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem Biophys Res Commun. 1972;46:849-854.
31. Wolf SP. Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Methods Enzymol. 1994;233:182-189.
32. Seekamp A, Mulligan MS, Till GO, Smith CW, Miyasaka M, Tamatani T, Todd RF 3rd, Ward PA. Role of beta 2 integrins and ICAM-1 in lung injury following ischemia-reperfusion of rat hind limbs. Am J Pathol. 1993;143:464-472. (Pubitemid 24058201)
33. Smith-Oliver T, Noel LS, Stimpson SS, Yarnall DP, Connolly KM. Elevated levels of TNF in the joints of adjuvant arthritic rats. Cytokine. 1993;5:298-304. (Pubitemid 23329659)
34. Tarpley J, John E. Preparation and sectioning of undecalcified frozen rodent long bones and joints using a tape transfer system. J Histotechnol. 2003;26:41-56.
35. Darlington LG, Stone TW. Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders. Br J Nutr. 2001;85:251-269. (Pubitemid 32293755)
36. Williams TJ. Prostaglandin E2, prostaglandin I2 and the vascular changes of inflammation. Br J Pharmacol. 1979;65:517-524.
37. Stuart J, Whicher JT. Tests for detecting and monitoring the acute phase response. Arch Dis Child. 1988;63:115-117. (Pubitemid 18058328)
38. Amos RS, Constable TJ, Crockson AP, McConkey B. Rheumatoid arthritis: relation of serum C-reactive protein and erythrocyte sedimentation rates to radiographic changes. Br Med J. 1977;1:195-197. (Pubitemid 8018411)
39. Dawes PT, Fowler PD, Clarke S, Fisher J, Lawton A, Shadford MF. Rheumatoid arthritis: treatment which controls the C-reactive protein and erythrocyte sedimentation rate reduces radiological progression. Br J Rheumatol. 1986;25:44-49. (Pubitemid 16156197)
40. Combe B, Dougados M, Goupille P, Cantagrel A, Eliaou JF, Sibila J, Meyer O, Sany J, Daures JP, Dubois A. Prognostic factors for radiographic damage in early rheumatoid arthritis: a multiparameter prospective study. Arthritis Rheum. 2001;44:1736-1743. (Pubitemid 32758218)
41. Babior BM, Kipnes RS, Curnutte JT. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest. 1973;52:741-744.
42. De Duve C, Wattiaux R. Functions of lysosomes. Annu Rev Physiol. 1966;28:435-492.
43. De Duve C. Lysosomes in pathology and therapeutics. Abstracts of the International Symposium on Lysosomes Hakone, Japan; 1972.
44. Carevic O, Djokic S. Comparative studies on the effect of erythromycin A and azithromycin upon extracellularly release of lysosomal enzymes in inflammatory process. Agents Action. 1988;1962(25):124-131.
45. Fahim AT, Abd-el Fattah AA, Agha AM, Gad MZ. Effect of pumpkin-seed oil on the level of free radical scavengers induced during adjuvant-arthritis in rats. Pharmacol Res. 1995;3:73-79.
46. Greenwald RA, Moy WW. Effect of oxygen-derived free radicals on hyaluronic acid. Arthr Rheum. 1980;23:455-463. (Pubitemid 10149454)
47. Goronzy JJ, Weyand CM. Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis. Trends Immunol. 2001;22:251-255. (Pubitemid 32667512)
48. Falgarone G, Semerano L, Rullé S, Boissier MC. Targeting lymphocyte activation to treat rheumatoid arthritis. Jt Bone Spine. 2009;76:327-332.
49. Abreu JR, Grabiec AM, Krausz S, Spijker R, Burakowski T, Maslinski W, Eldering E, Tak PP, Reedquist AK. The presumed hyporesponsive behavior of rheumatoid arthritis T lymphocytes can be attributed to spontaneous ex vivo apoptosis rather than defects in T cell receptor signaling. J Immunol. 2008;183:621-630.
50. Vandooren B, Noordenbos T, Ambarus C, Krausz S, Cantaert T, Yeremenko N, Boumans M, Lutter R, Tak PP, Baeten D. Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis. Arthritis Rheum. 2009;60:966-975.
51. Wang Y, Fang Y, Huang W, Zhou X, Wang M, Zhong B, Peng D. Effect of sinomenine on cytokine expression of macrophages and synoviocytes in adjuvant arthritis rats. J Ethnopharmacol. 2005;98:37-43. (Pubitemid 40349165)
52. Zangerle PF, De Groote D, Lopez M, Meuleman RJ, Vrindts Y, Fauchet F, Dehart I, Jadoul M, Radoux D, Franchimont P. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. II. Application to rheumatoid arthritis and osteoarthritis. Cytokine. 1992;4:568-575.
53. Gao J, Issekutz AC. The effect of ebselen on T-lymphocyte migration to arthritic joints and dermal inflammatory reactions in the rat. Int J Immunopharmacol. 1994;16:279-287. (Pubitemid 24128109)
54. Wilder RL, Lafyatis RT, Case JP, Yocum DE, Kumkumian KG, Remmers EF. Cytokines in rheumatoid arthritis and streptococcal cell wall arthritis in the rat. In: Lewis AJ, Doherty NS, Ackerman NR, editors. Therapeutic approaches to inflammatory diseases. Amsterdam: Elsevier; 1989. p. 27-32.