Phase i trial of selective internal radiation therapy for chemorefractory colorectal cancer liver metastases progressing after hepatic arterial pump and systemic chemotherapy

Clinical Colorectal Cancer

Volumn 13, Issue 1, 2014, Pages 27-36

  Sofocleous, Constantinos T ^a   Garcia, Alessandra R ^a   Pandit Taskar, Neeta ^a   Do, Kinh G ^a   Brody, Lynn A ^a   Petre, Elena N ^a   Capanu, Marinela ^a   Longing, Anne P ^a   Chou, Joanne F ^a   Carrasquillo, Jorge A ^a   Kemeny, Nancy E ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Arterially directed therapies; Hepatic arterial chemotherapy; Hepatic malignancy; Radioembolization; SIRT; Yttrium 90

Indexed keywords

ARTERIALLY DIRECTED THERAPIES; HEPATIC ARTERIAL CHEMOTHERAPY; HEPATIC MALIGNANCY; RADIOEMBOLIZATION; SIRT; YTTRIUM 90;

ADENOCARCINOMA; ADULT; AGED; BRACHYTHERAPY; COLORECTAL NEOPLASMS; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; MALE; MICROSPHERES; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; SALVAGE THERAPY; YTTRIUM RADIOISOTOPES;

EID: 84895074155     PISSN: 15330028     EISSN: 19380674     Source Type: Journal    
DOI: 10.1016/j.clcc.2013.11.010     Document Type: Article

References (44)

1. R. Adam, E. Hoti, and G. Folprecht et al. Accomplishments in 2008 in the management of curable metastatic colorectal cancer Gastrointest Cancer Res 3 2009 S15 S22
2. S.R. Alberts, and G.J. Poston Treatment advances in liver-limited metastatic colorectal cancer Clin Colorectal Cancer 10 2011 258 265
3. J.B. Ammori, and N.E. Kemeny Regional hepatic chemotherapies in treatment of colorectal cancer metastases to the liver Semin Oncol 37 2010 139 148
4. M. Lorenz, H.H. Muller, and H. Schramm et al. Randomized trial of surgery versus surgery followed by adjuvant hepatic arterial infusion with 5-fluorouracil and folinic acid for liver metastases of colorectal cancer. German Cooperative on Liver Metastases (Arbeitsgruppe Lebermetastasen) Ann Surg 228 1998 756 762
5. N.J. Lygidakis, G. Sgourakis, and L. Vlachos et al. Metastatic liver disease of colorectal origin: the value of locoregional immunochemotherapy combined with systemic chemotherapy following liver resection. Results of a prospective randomized study Hepatogastroenterology 48 2001 1685 1691
6. N.E. Kemeny, W.R. Jarnagin, and M. Capanu et al. Randomized phase II trial of adjuvant hepatic arterial infusion and systemic chemotherapy with or without bevacizumab in patients with resected hepatic metastases from colorectal cancer J Clin Oncol 29 2011 884 889
7. A.M. Campbell, I.H. Bailey, and M.A. Burton Analysis of the distribution of intra-arterial microspheres in human liver following hepatic yttrium-90 microsphere therapy Phys Med Biol 45 2000 1023 1033
8. A. Kennedy, S. Nag, and R. Salem et al. Recommendations for radioembolization of hepatic ç using yttrium-90 microsphere brachytherapy: a consensus panel report from the Radioembolization Brachytherapy Oncology Consortium Int J Radiat Oncol Biol Phys 68 2007 13 23
9. A.S. Kennedy, C. Nutting, and D. Coldwell et al. Pathologic response and microdosimetry of 90Y microspheres in man: review of four explanted whole livers Int J Radiat Oncol Biol Phys 60 2004 552 563
10. M.F. Mulcahy, R.J. Lewandowski, and S.M. Ibrahim et al. Radioembolization of colorectal hepatic metastases using yttrium-90 microspheres Cancer 115 2009 1849 1858
11. A.M. Campbell, I.H. Bailey, and M.A. Burton Tumour dosimetry in human liver following hepatic yttrium-90 microsphere therapy Phys Med Biol 46 2001 487 498
12. R.A. Sharma, G.A. Van Hazel, and B. Morgan et al. Radioembolization of liver metastases from colorectal cancer using yttrium-90 microspheres with concomitant systemic oxaliplatin, fluorouracil, and leucovorin chemotherapy J Clin Oncol 25 2007 1099 1106
13. T.F. Jakobs, R.T. Hoffmann, and K. Dehm et al. Hepatic yttrium-90 radioembolization of chemotherapy-refractory colorectal cancer liver metastases J Vasc Interv Radiol 19 2008 1187 1195
14. M.A. Vente, M. Wondergem, and I. van der Tweel et al. Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis Eur Radiol 19 2009 951 959
15. D. Coldwell, B. Sangro, and R. Salem et al. Radioembolization in the treatment of unresectable liver tumors: experience across a range of primary cancers Am J Clin Oncol 35 2012 167 177
16. M. Cosimelli, R. Golfieri, and P.P. Cagol et al. Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases Br J Cancer 103 2010 324 331
17. A. Hendlisz, M. Van den Eynde, and M. Peeters et al. Phase III trial comparing protracted intravenous fluorouracil infusion alone or with yttrium-90 resin microspheres radioembolization for liver-limited metastatic colorectal cancer refractory to standard chemotherapy J Clin Oncol 28 2010 3687 3694
18. L. Bester, B. Meteling, and N. Pocock et al. Radioembolization versus standard care of hepatic metastases: comparative retrospective cohort study of survival outcomes and adverse events in salvage patients J Vasc Interv Radiol 23 2012 96 105
19. R.J. Lewandowski, K.G. Thurston, and J.E. Goin et al. 90Y microsphere (TheraSphere) treatment for unresectable colorectal cancer metastases of the liver: Response to treatment at targeted doses of 135-150 Gy as measured by [18F]fluorodeoxyglucose positron emission tomography and computed tomographic imaging J Vasc Interv Radiol 16 2005 1641 1651
20. K. Memon, R.J. Lewandowski, and L. Kulik et al. Radioembolization for primary and metastatic liver cancer Semin Radiat Oncol 21 2011 294 302
21. B. Gray, G. Van Hazel, and M. Hope et al. Randomised trial of SIR-Spheres plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer Ann Oncol 12 2001 1711 1720
22. G. Van Hazel, A. Blackwell, and J. Anderson et al. Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer J Surg Oncol 88 2004 78 85
23. R. Cianni, C. Urigo, and E. Notarianni et al. Selective internal radiation therapy with SIR-spheres for the treatment of unresectable colorectal hepatic metastases Cardiovasc Intervent Radiol 32 2009 1179 1186
24. S. Kosmider, T.H. Tan, and D. Yip et al. Radioembolization in combination with systemic chemotherapy as first-line therapy for liver metastases from colorectal cancer J Vasc Interv Radiol 22 2011 780 786
25. G.A. van Hazel, N. Pavlakis, and D. Goldstein et al. Treatment of fluorouracil-refractory patients with liver metastases from colorectal cancer by using yttrium-90 resin microspheres plus concomitant systemic irinotecan chemotherapy J Clin Oncol 27 2009 4089 4095
26. A.S. Kennedy, D. Coldwell, and C. Nutting et al. Resin 90Y-microsphere brachytherapy for unresectable colorectal liver metastases: modern USA experience Int J Radiat Oncol Biol Phys 65 2006 412 425
27. Activity Calculator. Available at: http://apps01.sirtex.com/smac/. Accessed: July 30, 2013.
28. P. Therasse, S.G. Arbuck, and E.A. Eisenhauer et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl Cancer Inst 92 2000 205 216
29. A.R. Haug, B.P. Tiega Donfack, and C. Trumm et al. 18F-FDG PET/CT predicts survival after radioembolization of hepatic metastases from breast cancer J Nucl Med 53 2012 371 377
30. R.L. Wahl, H. Jacene, and Y. Kasamon et al. From RECIST to PERCIST: Evolving Considerations for PET response criteria in solid tumors J Nucl Med 50 Suppl 1 2009 122S 150S
31. I. Zerizer, A. Al-Nahhas, and D. Towey et al. The role of early (1)(8)F-FDG PET/CT in prediction of progression-free survival after (9)(0)Y radioembolization: comparison with RECIST and tumour density criteria Eur J Nucl Med Mol Imaging 39 2012 1391 1399
32. M.J. Goldstein, and E.P. Mitchell Carcinoembryonic antigen in the staging and follow-up of patients with colorectal cancer Cancer Invest 23 2005 338 351
33. T.D. Yan, D.R. Nunn, and D.L. Morris Recurrence after complete cryoablation of colorectal liver metastases: Analysis of prognostic features American Surgeon 72 2006 382 390
34. S.M. Tochetto, H.G. Töre, and H. Chalian et al. Colorectal liver metastasis after 90Y radioembolization therapy: Pilot study of change in MDCT attenuation as a surrogate marker for future FDG PET response AJR Am J Roentgenol 198 2012 1093 1099
35. R. Lencioni, and J.M. Llovet Modified RECIST (mRECIST) assessment for hepatocellular carcinoma Semin Liver Dis 30 2010 52 60
36. R. Lencioni New data supporting modified RECIST (mRECIST) for hepatocellular carcinoma Clin Cancer Res 19 2013 1312 1314
37. C. Le Tourneau, J.J. Lee, and L.L. Siu Dose escalation methods in phase I cancer clinical trials J Natl Cancer Inst 101 2009 708 720
38. R. Seidensticker, T. Denecke, and P. Kraus et al. Matched-pair comparison of radioembolization plus best supportive care versus best supportive care alone for chemotherapy refractory liver-dominant colorectal metastases Cardiovasc Intervent Radiol 35 2012 1066 1073
39. R. Salem, R.J. Lewandowski, and V.L. Gates et al. Research reporting standards for radioembolization of hepatic malignancies J Vasc Interv Radiol 22 2011 265 278
40. B. Sangro, B. Gil-Alzugaray, and J. Rodriguez et al. Liver disease induced by radioembolization of liver tumors: description and possible risk factors Cancer 112 2008 1538 1546
41. R. Seidensticker, M. Seidensticker, and R. Damm et al. Hepatic toxicity after radioembolization of the liver using 90Y-microspheres: sequential lobar versus whole liver approach Cardiovasc Intervent Radiol 2011 1 10
42. B. Janne d'Othee, C.T. Sofocleous, and N. Hanna et al. Development of a research agenda for the management of metastatic colorectal cancer: proceedings from a multidisciplinary research consensus panel J Vasc Interv Radiol 23 2012 153 163
43. A.R. Haug, V. Heinemann, and C.J. Bruns et al. 18F-FDG PET independently predicts survival in patients with cholangiocellular carcinoma treated with 90Y microspheres Eur J Nucl Med Mol Imaging 38 2011 1037 1045
44. B. Atassi, A.K. Bangash, and A. Bahrani et al. Multimodality imaging following 90Y radioembolization: a comprehensive review and pictorial essay Radiographics 28 2008 81 99