Moderate dose cranial radiotherapy causes central adrenal insufficiency in long-term survivors of childhood leukaemia

Pituitary

Volumn 17, Issue 1, 2014, Pages 7-12

  Follin, C ^a   Wiebe, T ^a   Moell C ^a   Erfurth, E M ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Central adrenal insufficiency; Childhood acute lymphoblastic leukaemia; Cranial radiotherapy; GH deficiency

Indexed keywords

ADOLESCENT; ADRENAL INSUFFICIENCY; ADRENOCORTICOTROPIC HORMONE; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; GROWTH HORMONE; HUMAN GROWTH HORMONE; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INFANT; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MALE; PITUITARY-ADRENAL SYSTEM; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SURVIVORS;

EID: 84895073563     PISSN: 1386341X     EISSN: 15737403     Source Type: Journal    
DOI: 10.1007/s11102-012-0459-8     Document Type: Article

References (22)

1. Oeffinger KC, Eshelman DA, Tomlinson GE, Tolle M, Schneider GW (2000) Providing primary care for long-term survivors of childhood acute lymphoblastic leukemia. J Fam Pract 49:1133-1146
2. Shalet S, Beardwell CG, Pearson D (1976) The effect of varying doses of cerebral irradiation on growth hormone production in childhood. Clin Endocrinol (Oxf) 5:287-290
3. Littley M, Shalet S, Beardwell C (1990) Radiation and hypothalamic-pituitary function. Baillieres Clin Endocrin Metab 4:147-175
4. Brennan BMD, Rahim A, Mackie EM, Eden O, Shalet S (1998) Growth hormone status in adults treated for acute lymphoblastic leukaemia in childhood. Clin Endocrinol 48:777-783
5. Link K, Moëll C, Garwicz S, Cavallin-Ståhl E, Björk J, Thilén U, Ahrén B, Erfurth EM (2004) Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukaemia in childhood. J Clin Endocrin Metab 89:5005-5012
6. Follin C, Link K, Wiebe T, Moëll C, Björk J, Erfurth EM (2012) Prolactin insufficiency but normal thyroid hormone levels after cranial radiotherapy in long-term survivors of childhood leukaemia. Clin Endocrinol (Oxf). doi: 10.1111/cen.12111
7. Oberfield SE, Nirenberg A, Allen J, Cohen H, Donahue B, Prasad V, Schiff R, Pang S, Ghavimi F, David R, Chrousos G, Sklar C (1997) Hypothalamic- pituitary-adrenal function following cranial irradiation. Horm Res 47:9-16
8. Spoudeas HA, Charmandari E, Brook CGD (2003) Hypothalamo-Pituitary- Adrenal axis integrity after cranial irradiation for childhood posterior fossa tumours. Med Pediatr Oncol 40:224-229
9. Rose S, Danish R, Kearny N, Schreiber R, Lustig R, Burghen G, Husdon M (2005) ACTH deficiency in childhood cancer survivors. Pediatr Blood Cancer 45:808-813
10. Patterson B, Truxillo L, Wasilewski-Masker K, Mertens A, Meacham L (2009) Adrenal testing in pediatric cancer survivors. Pediatr Blood Cancer 53:1302-1307
11. Crowne E, Wallace H, Gibson S, Moore M, White A, Shalet S (1993) Adrenocorticotrophin and cortisol secretion in children after low dose cranial irradiation. Clin Endocrinol 39:297-305
12. Constine L, Wolf P, Cann D, Mick G, McCormick K, Raubertas R, Rubin P (1993) Hypothalamic-Pituitary dysfunction after radiation for brain tumours. N Engl J Med 328:87-94
13. Heikens J, Michiels E, Behrendt H, Endert E, Bakker P, Fliers E (1998) Long-term Neuro-enocrine sequele after treatment for childhood medulloblastoma. Eur J Cancer 34:1592-1597
14. Schmiegelow M, Feldt-Rasmussen U, Rasmussen A, Lange M, Poulsen H, Müller J (2003) Assessment of the hypothalamic-pituitary-adrenal axis in patients treated with radiotherapy and chemotherapy for childhood brain tumour. J Clin Endocrinol Metab 88:3149-3154
15. Corneli G, Di Soma C, Baldelli R, Rovere S, Gasco V, Croce CG, Grottoli S, Maccario M, Colao A, Lombardi G, Ghigo E, Camanni F, Aimaretti G (2005) The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index. Euro J Endocrin 153:257-264
16. Hurel SJ, Thompson CJ, Watson MJ, Harris MM, Baylis PH, Kendall-Taylor P (1996) The short Synacthen and insulin stress tests in the assessment of the hypothalamic-pituitary-adrenal axis. Clin Endocrinol 44:141-146
17. Stewart PM, Murry BA, Mason JI (1994) Human kidney 11 beta-hydroxysteriod dehydrogenase is a high affinity nicotinamide adenine dinucleotide-dependent enzyme and differs from the cloned type I isoform. J Clin Endocrinol Metab 79:480-484
18. Giavoli C, Bergamaschi Ferrante E, Ronchi C, Lania A, Rusconi R, Spada A, Beck-Peccoz P (2008) Effect of growth hormone deficiency and recombinant hGH (rhGH) replacement on the hypothalamic-pituitary-adrenal axis in children with idiopathic isolated GH deficiency. Clin Endocrinol 68:247-251
19. Giavoli C, Libé R, Corbetta S, Ferrante E, Lania A, Arosio M, Spada A, Beck-Peccoz P (2004) Effect of recombinant human growth hormone (GH) replacement on the hypothalamic-pituitary-adrenal axis in adult GH-deficient patients. J Clin Endocrinol Metab 89:5397-5401
20. The growth hormone research society (GRS) (1998) Consensus guidelines for the diagnosis and treatment of adults with GH deficiency: summary statement of the GRS workshop on adults GHD. J Clin Endocrinol Metab 34:379-381
21. Darzy K, Aimaretti W, Gattamaneni R (2003) The usefulness of the combined growth hormone (GH) - releasing hormone and arginine stimulation test in the diagnosis of radiation-induced GH deficiency is dependent on the post-irradiation time interval. J Clin Endocrinol Metab 88:95-102
22. Children's Oncology Group Guidelines (2008) Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers. www.survivorshipguidlines.org