Effects of hydroxysafflor yellow A on the activity and mRNA expression of four CYP isozymes in rats

Journal of Ethnopharmacology

Volumn 151, Issue 3, 2014, Pages 1141-1146

  Xu, Ren Ai ^a   Xu, Zhi Sheng ^a   Ge, Ren Shan ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Cocktail; CYP; Hydroxysafflor yellow A; mRNA; Probe drugs; Real time RT PCR

Indexed keywords

CARBAMAZEPINE (PUBCHEM CID: 2554); COCKTAIL; CYP; DEXTROMETHORPHAN (PUBCHEM CID: 5360696); HYDROXYSAFFLOR YELLOW A; HYDROXYSAFFLOR YELLOW A (PUBCHEM CID: 6443665); MIDAZOLAM (PUBCHEM CID: 4192); MRNA; PHENACETIN (PUBCHEM CID: 4754); PROBE DRUGS; REAL-TIME RT-PCR; TOLBUTAMIDE (PUBCHEM CID: 5505);

ANIMALS; CHALCONE; CYTOCHROME P-450 ENZYME SYSTEM; DEXTROMETHORPHAN; HERB-DRUG INTERACTIONS; ISOENZYMES; LIVER; MALE; MIDAZOLAM; PHENACETIN; QUINONES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TOLBUTAMIDE;

EID: 84895072228     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.12.025     Document Type: Article

References (24)

1. X.D. Bie, J. Han, and H.B. Dai Effects of hydroxysafflor yellow A on the experimental traumatic brain injury in rats J. Asian Nat. Prod. Res. 12 2010 239 247
2. D.D. Breimer Interindividual variations in drug disposition. Clinical implications and methods of investigation Clin. Pharmacokinet. 8 1983 371 377 (Pubitemid 13007562)
3. E. Chan, M. Tan, J.N. Xin, S. Sudarsanam, and D.E. Johnson Interactions between traditional Chinese medicines and Western therapeutics Curr. Opin. Drug Discovery 13 2010 50 65
4. A.K. Daly Pharmacogenetics of the cytochromes P450 Curr. Top Med. Chem. 4 2004 1733 1744 (Pubitemid 39654459)
5. D.A. Flockhart, and J.R. Oesterheld Cytochrome P450-mediated drug interactions Child Adolesc. Psychiatr. Clin. N. Am. 9 2000 43 76 (Pubitemid 30261718)
6. J. Gao, Z. Shi, S. Zhu, G.Q. Li, R. Yan, and M. Yao Influences of processed rhubarbs on the activities of four CYP isozymes and the metabolism of saxagliptin in rats based on probe cocktail and pharmacokinetics approaches J. Ethnopharmacol. 145 2013 566 572
7. K. Jiang, K. Li, F. Qin, X. Lu, and F. Li Assessment of a novel beta2-adrenoceptor agonist, trantinterol, for interference with human liver cytochrome P450 enzymes activities Toxicol. In Vitro 25 2011 1033 1038
8. M. Jin, J.R. Li, and W. Wu Study on the antioxidative effect of Safflor Yellow Zhongguo Zhong Yao Za Zhi 29 2004 447 449
9. K.T. Kivisto, and H.K. Kroemer Use of probe drugs as predictors of drug metabolism in humans J. Clin. Pharmacol. 37 1997 40S 48S (Pubitemid 27123980)
10. S.Z. Kong, Y.F. Xian, S.P. Ip, X.P. Lai, X.G. Shi, Z.X. Lin, and Z.R. Su Protective effects of hydroxysafflor yellow A on beta-amyloid-induced neurotoxicity in PC12 cells Neurochem. Res. 38 2013 951 960
11. D.F. Lewis P450 structures and oxidative metabolism of xenobiotics Pharmacogenomics 4 2003 387 395 (Pubitemid 36857175)
12. Y. Li, and Q. Che [Studies on chemical components of Carthamus tinctorius petals] Yao Xue Xue Bao 33 1998 626 628 (Pubitemid 128466335)
13. S.K. Lu, S.M. Callahan, and L.J. Brunner Suppression of hepatic CYP3A1/2 and CYP2C11 by cyclosporine is not mediated by altering growth hormone levels J. Pharmacol. Exp. Ther. 305 2003 331 337 (Pubitemid 36373868)
14. M. Martignoni, G.M. Groothuis, and R. de Kanter Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction Expert Opin. Drug Metabol. Toxicol. 2 2006 875 894 (Pubitemid 44911538)
15. P. Mustajoki, S. Mustajoki, A. Rautio, P. Arvela, and O. Pelkonen Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men Clin. Pharmacol. Ther. 56 1994 9 13 (Pubitemid 24251559)
16. P.H. Nie, L. Zhang, W.H. Zhang, W.F. Rong, and J.M. Zhi The effects of hydroxysafflor yellow A on blood pressure and cardiac function J. Ethnopharmacol. 139 2012 746 750
17. R. Nowack Review article: cytochrome P450 enzyme, and transport protein mediated herb-drug interactions in renal transplant patients: grapefruit juice St. John's Wort - and beyond! Nephrology (Carlton) 13 2008 337 347 (Pubitemid 351668338)
18. X. Shi, D. Ruan, Y. Wang, L. Ma, and M. Li Anti-tumor activity of safflower polysaccharide (SPS) and effect on cytotoxicity of CTL cells, NK cells of T739 lung cancer in mice Zhongguo Zhong Yao Za Zhi 35 2010 215 218
19. T. Su, C. Mao, F. Yin, Z. Yu, Y. Lin, Y. Song, and T. Lu Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats J. Ethnopharmacol. 146 2013 734 743
20. J. Tian, G. Li, Z. Liu, and F. Fu Hydroxysafflor yellow A inhibits rat brain mitochondrial permeability transition pores by a free radical scavenging action Pharmacology 82 2008 121 126
21. Y.C. Tien, J.Y. Lin, C.H. Lai, C.H. Kuo, W.Y. Lin, C.H. Tsai, F.J. Tsai, Y.C. Cheng, W.H. Peng, and C.Y. Huang Carthamus tinctorius L. prevents LPS-induced TNFalpha signaling activation and cell apoptosis through JNK1/2-NFkappaB pathway inhibition in H9c2 cardiomyoblast cells J. Ethnopharmacol. 130 2010 505 513
22. Y. Wu, L. Wang, M. Jin, and B.X. Zang Hydroxysafflor yellow A alleviates early inflammatory response of bleomycin-induced mice lung injury Biol. Pharm. Bull. 35 2012 515 522
23. B.X. Zang, M. Jin, N. Si, Y. Zhang, W. Wu, and Y.Z. Piao Antagonistic effect of hydroxysafflor yellow A on the platelet activating factor receptor Yao Xue Xue Bao 37 2002 696 699
24. Y. Zhang, J. Guo, H. Dong, X. Zhao, L. Zhou, X. Li, J. Liu, and Y. Niu Hydroxysafflor yellow A protects against chronic carbon tetrachloride-induced liver fibrosis Eur. J. Pharmacol. 660 2011 438 444