Dienogest inhibits nerve growth factor expression induced by tumor necrosis factor-α or interleukin-1β

Fertility and Sterility

Volumn 101, Issue 2, 2014, Pages

  Mita, Shizuka ^a   Shimizu, Yutaka ^a   Sato, Ayumi ^a   Notsu, Tatsuto ^a   Imada, Kazunori ^a   Kyo, Satoru ^b  

^a MOCHIDA PHARMACEUTICAL CO   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Dienogest; endometrial epithelial cells; nerve growth factor; P receptor

Indexed keywords

DIENOGEST; INTERLEUKIN 1BETA; MESSENGER RNA; NERVE GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BASIC RESEARCH; BIOLOGICAL ACTIVITY; CELL IMMORTALIZATION; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; ENDOMETRIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

DIENOGEST; ENDOMETRIAL EPITHELIAL CELLS; NERVE GROWTH FACTOR; P RECEPTOR;

ANIMALS; CELL LINE, TRANSFORMED; FEMALE; HORMONE ANTAGONISTS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; NANDROLONE; NERVE GROWTH FACTOR; PC12 CELLS; PROSPECTIVE STUDIES; RATS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84895068008     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.10.038     Document Type: Article

References (57)

1. P.L. McCormack Dienogest: a review of its use in the treatment of endometriosis Drugs 70 2010 2073 2088
2. M. Momoeda, T. Harada, N. Terakawa, T. Aso, M. Fukunaga, and H. Hagino et al. Long-term use of dienogest for the treatment of endometriosis J Obstet Gynaecol Res 35 2009 1069 1076
3. T. Harada, M. Momoeda, Y. Taketani, T. Aso, M. Fukunaga, and H. Hagino et al. Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis - a randomized, double-blind, multicenter, controlled trial Fertil Steril 91 2009 675 681
4. T. Strowitzki, J. Marr, C. Gerlinger, T. Faustmann, and C. Seitz Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial Hum Reprod 25 2010 633 641
5. F. Petraglia, D. Hornung, C. Seitz, T. Faustmann, C. Gerlinger, and S. Luisi et al. Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment Arch Gynecol Obstet 285 2012 167 173
6. P. Crosignani, D. Olive, A. Bergqvist, and A. Luciano Advances in the management of endometriosis: an update for clinicians Hum Reprod Update 12 2006 179 189
7. M. Izawa, F. Taniguchi, N. Terakawa, and T. Harada Epigenetic aberration of gene expression in endometriosis Front Biosci E5 2013 900 910
8. M. Irahara, T. Harada, M. Momoeda, and Y. Tamaki Hormonal and histological study on irregular genital bleeding in patients with endometriosis during treatment with dienogest, a novel progestational therapeutic agent Reprod Med Biol 6 2007 223 228
9. 1 arrest in cultured endometriotic stromal cells Fertil Steril 89 2008 1344 1347
10. S. Horie, T. Harada, M. Mitsunari, F. Taniguchi, T. Iwabe, and N. Terakawa Progesterone and progestational compounds attenuate tumor necrosis factor alpha-induced interleukin-8 production via nuclear factor kappaB inactivation in endometriotic stromal cells Fertil Steril 83 2005 1530 1535
11. 2 production in human endometriotic stromal cells in spheroid culture Fertil Steril 97 2012 477 482
12. O. Triolo, A.S. Laganà, and E. Sturlese Chronic pelvic pain in endometriosis: an overview J Clin Med Res 5 2013 153 163
13. F.M. Howard Endometriosis and mechanisms of pelvic pain J Minim Invasive Gynecol 16 2009 540 550
14. A.J. Hey-Cunningham, K.M. Peters, H. Barrera-Villa Zevallos, M. Berbic, R. Markham, and I.S. Fraser Angiogenesis, lymphangiogenesis and neurogenesis in endometriosis Front Biosci E5 2013 1033 1056
15. J.K. Cheng, and R.R. Ji Intracellular signaling in primary sensory neurons and persistent pain Neurochem Res 33 2008 1970 1978
16. S. Pezet, and S.B. McMahon Neurotrophins: mediators and modulators of pain Annu Rev Neurosci 29 2006 507 538
17. M. Scuri, L. Samsell, and G. Piedimonte The role of neurotrophins in inflammation and allergy Inflamm Allergy Drug Targets 9 2010 173 180
18. M.F. Seidel, M. Herguijuela, R. Forkert, and U. Otten Nerve growth factor in rheumatic diseases Semin Arthritis Rheum 40 2010 109 126
19. V. Anaf, P. Simon, I. El Nakadi, I. Fayt, T. Simonart, and F. Buxant et al. Hyperalgesia, nerve infiltration and nerve growth factor expression in deep adenomyotic nodules, peritoneal and ovarian endometriosis Hum Reprod 17 2002 1895 1900
20. N. Tokushige, R. Markham, P. Russell, and I.S. Fraser Nerve fibres in peritoneal endometriosis Hum Reprod 21 2006 3001 3007
21. N. Tokushige, R. Markham, P. Russell, and I.S. Fraser Effects of hormonal treatment on nerve fibers in endometrium and myometrium in women with endometriosis Fertil Steril 90 2008 1589 1598
22. N. Tokushige, R. Markham, P. Russell, and I.S. Fraser Effect of progestogens and combined oral contraceptives on nerve fibers in peritoneal endometriosis Fertil Steril 92 2009 1234 1239
23. M.L. Barcena de Arellano, J. Arnold, H. Lang, G.F. Vercellino, V. Chiantera, and A. Schneider et al. Evidence of neurotrophic events due to peritoneal endometriotic lesions Cytokine 62 2013 253 261
24. M.L. Barcena de Arellano, J. Arnold, F. Vercellino, V. Chiantera, A. Schneider, and S. Mechsner Overexpression of nerve growth factor in peritoneal fluid from women with endometriosis may promote neurite outgrowth in endometriotic lesions Fertil Steril 95 2011 1123 1126
25. M.L. Barcena de Arellano, J. Arnold, G.F. Vercellino, V. Chiantera, A.D. Ebert, and A. Schneider et al. Influence of nerve growth factor in endometriosis-associated symptoms Reprod Sci 18 2011 1202 1210
26. J. Arnold, M.L. Barcena de Arellano, C. Rüster, G.F. Vercellino, V. Chiantera, and A. Schneider et al. Imbalance between sympathetic and sensory innervation in peritoneal endometriosis Brain Behav Immun 26 2012 132 141
27. S. Mechsner, J. Schwarz, J. Thode, C. Loddenkemper, D.S. Salomon, and A.D. Ebert Growth-associated protein 43-positive sensory nerve fibers accompanied by immature vessels are located in or near peritoneal endometriotic lesions Fertil Steril 88 2007 581 587
28. S. Mechsner, A. Kaiser, A. Kopf, C. Gericke, A. Ebert, and J. Bartley A pilot study to evaluate the clinical relevance of endometriosis-associated nerve fibers in peritoneal endometriotic lesions Fertil Steril 92 2009 1856 1861
29. S. Mita, Y. Shimizu, T. Notsu, K. Imada, and S. Kyo Dienogest inhibits Toll-like receptor 4 expression induced by costimulation of lipopolysaccharide and high-mobility group box 1 in endometrial epithelial cells Fertil Steril 96 2011 1485 1489
30. 2 production and aromatase expression by human endometrial epithelial cells in a spheroid culture system Steroids 76 2011 60 67
31. M.H. Wu, H.S. Sun, C.C. Lin, K.Y. Hsiao, P.C. Chuang, and H.A. Pan et al. Distinct mechanisms regulate cyclooxygenase-1 and -2 in peritoneal macrophages of women with and without endometriosis Mol Hum Reprod 8 2002 1103 1110
32. S. Kyo, M. Nakamura, T. Kiyono, Y. Maida, T. Kanaya, and M. Tanaka et al. Successful immortalization of endometrial glandular cells with normal structural and functional characteristics Am J Pathol 163 2003 2259 2269
33. Y. Shimizu, T. Takeuchi, S. Mita, K. Mizuguchi, T. Kiyono, and M. Inoue et al. Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression Mol Hum Reprod 15 2009 693 701
34. M. Nakamura, M. Takakura, R. Fujii, Y. Maida, Y. Bono, and Y. Mizumoto et al. The PRB-dependent FOXO1/IGFBP-1 axis is essential for progestin to inhibit endometrial epithelial growth Cancer Lett 336 2013 68 75
35. Y. Bono, S. Kyo, M. Takakura, Y. Maida, Y. Mizumoto, and M. Nakamura et al. Creation of immortalised epithelial cells from ovarian endometrioma Br J Cancer 106 2012 1205 1213
36. G.W. Varilek, G.A. Neil, W.P. Bishop, J. Lin, and N.J. Pantazis Nerve growth factor synthesis by intestinal epithelial cells Am J Physiol 269 1995 G445 G452
37. D.E. Bjorling, M. Beckman, M.K. Clayton, and Z.Y. Wang Modulation of nerve growth factor in peripheral organs by estrogen and progesterone Neuroscience 110 2002 155 167
38. Z. Shi, K.Y. Arai, W. Jin, Q. Weng, G. Watanabe, and A.K. Suzuki et al. Expression of nerve growth factor and its receptors NTRK1 and TNFRSF1B is regulated by estrogen and progesterone in the uteri of golden hamsters Biol Reprod 74 2006 850 856
39. Y.S. Choi, S. Cho, K.J. Lim, Y.E. Jeon, H.I. Yang, and K.E. Lee et al. Effects of LNG-IUS on nerve growth factor and its receptors expression in patients with adenomyosis Growth Factors 28 2010 452 460
40. C.K. Bose Neurotrophin in obstetrics and gynaecology J Stem Cells 4 2009 217 227
41. A. Antonelli, G. Lapucci, E. Vigneti, S. Bonini, and L. Aloe Human lung fibroblast response to NGF, IL-1β, and dexamethsone Lung 183 2005 337 351
42. V. Freund, F. Pons, V. Joly, E. Mathieu, N. Martinet, and N. Frossard Upregulation of nerve growth factor expression by human airway smooth muscle cells in inflammatory conditions Eur Respir J 20 2002 458 463
43. A. Hattori, E. Tanaka, K. Murase, N. Ishida, Y. Chatani, and M. Tsujimoto et al. Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells J Biol Chem 268 1993 2577 2582
44. C. Kemi, J. Grunewald, A. Eklund, and C.O. Höglund Differential regulation of neurotrophin expression in human bronchial smooth muscle cells Respir Res 7 2006 18
45. D. Lindholm, R. Heumann, B. Hengerer, and H. Thoenen Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts J Biol Chem 263 1988 16348 16351
46. C. Olgart, and N. Frossard Human lung fibroblasts secrete nerve growth factor: effect of inflammatory cytokines and glucocorticoids Eur Respir J 18 2001 115 121
47. M.R. Peeraully, J.R. Jenkins, and P. Trayhurn NGF gene expression and secretion in white adipose tissue: regulation in 3T3-L1 adipocytes by hormones and inflammatory cytokines Am J Physiol Endocrinol Metab 287 2004 E331 E339
48. F. Pons, V. Freund, H. Kuissu, E. Mathieu, C. Olgart, and N. Frossard Nerve growth factor secretion by human lung epithelial A549 cells in pro- and anti-inflammatory conditions Eur J Pharmacol 428 2001 365 369
49. A. Hayashi, A. Tanabe, S. Kawabe, M. Hayashi, H. Yuguchi, and Y. Yamashita et al. Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis J Ovarian Res 5 2012 31
50. B.M. Jacobsen, and K.B. Horwitz Progesterone receptors, their isoforms and progesterone regulated transcription Mol Cell Endocrinol 357 2012 18 29
51. V. Freund-Michel, and N. Frossard The nerve growth factor and its receptors in airway inflammatory diseases Pharmacol Ther 117 2008 52 76
52. D. Dai, E.S. Litman, E. Schonteich, and K.K. Leslie Progesterone regulation of activating protein-1 transcriptional activity: a possible mechanism of progesterone inhibition of endometrial cancer cell growth J Steroid Biochem Mol Biol 87 2003 123 131
53. D.B. Hardy, B.A. Janowski, D.R. Corey, and C.R. Mendelson Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-κB activation of cyclooxygenase 2 expression Mol Endocrinol 20 2006 2724 2733
54. E. Kalkhoven, S. Wissink, P.T. van der Saag, and B. van der Burg Negative interaction between the RelA(p65) subunit of NF-κB and the progesterone receptor J Biol Chem 271 1996 6217 6224
55. V. Anaf, C. Chapron, I. El Nakadi, V. De Moor, T. Simonart, and J.C. Noël Pain, mast cells, and nerves in peritoneal, ovarian, and deep infiltrating endometriosis Fertil Steril 86 2006 1336 1343
56. G. Wang, N. Tokushige, R. Markham, and I.S. Fraser Rich innervation of deep infiltrating endometriosis Hum Reprod 24 2009 827 834
57. M. Oettel, S. Bervoas-Martin, W. Elger, S. Golbs, G. Hobe, and G. Kaufmann et al. A 19-norprogestin without a 17α-ethinyl group I: dienogest from a pharmacokinetic point of view Drugs Today 31 1995 499 516