Flow cytometric analysis of CD133- and EpCAM-positive cells in the peripheral blood of patients with lung cancer

Archivum Immunologiae et Therapiae Experimentalis

Volumn 62, Issue 1, 2014, Pages 67-75

  Skirecki, Tomasz ^a,b   Hoser, Grazyna ^a   Kawiak, Jerzy ^d   Dziedzic, Dariusz ^c   Domagała Kulawik, Joanna ^b  

^a MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

^c NATIONAL TUBERCULOSIS AND LUNG DISEASES RESEARCH INSTITUTE   (Poland)

^d INSTITUTE OF BIOCYBERNETICS AND BIOMEDICAL ENGINEERING   (Poland)

Author keywords

Cancer stem cell (CSC); CD133; EpCAM; Lung cancer; Metastases

Indexed keywords

BREAST NEOPLASMS; FEMALE; FLOW CYTOMETRY; HUMANS;

EID: 84895067962     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-013-0250-1     Document Type: Article

References (30)

1. Alberg AJ, Ford JG, Samet JM (2007) Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition). Chest 132(3 suppl):29S-55S
2. Al-Hajj M, Wicha MS, Benito-Hernandez A et al (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100:3983-3988
3. Baeuerle PA, Gires O (2007) EpCAM (CD326) finding its role in cancer. Br J Cancer 96:417-423
4. Chen YC, Hsu HS, Chen YW et al (2008) Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells. PLoS ONE 3:e2637
5. Clevers H (2011) The cancer stem cell: premises, promises and challenges. Nat Med 17:313-319
6. Devriese LA, Bosma AJ, van de Heuvel MM et al (2012) Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis. Lung Cancer 75:242-247
7. Dome B, Timar J, Dobos J et al (2006) Identification and clinical significance of circulating endothelial progenitor cells in human non-small cell lung cancer. Cancer Res 66:7341-7347
8. Draper JS, Pigott C, Thomson JA et al (2002) Surface antigens of human embryonic stem cells: changes upon differentiation in culture. J Anat 200(Pt 3):249-258
9. Eramo A, Lotti F, Sette G et al (2008) Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ 15:504-514
10. Goldstraw P (ed) (2009) Staging manual in thoracic oncology, International Association for the Study of Lung Cancer, 1st edn. Editorial Rx Press, Orange Park
11. Jemal A, Siegel R, Xu J et al (2010) Cancer statistics. CA Cancer J Clin 60:277-300
12. Kim Y, Kim HS, Cui ZY et al (2009) Clinicopathological implications of EpCAM expression in adenocarcinoma of the lung. Anticancer Res 29:1817-1822
13. Krebs MG, Sloane R, Priest L et al (2011) Evaluation and prognostic significance of circulating tumor cells in patients with non-small-cell lung cancer. J Clin Oncol 29:1556-1563
14. Krzakowski M (2010) Recommendations on systemic treatment of non-small cell lung cancer and malignant pleural mesothelioma. Pneumonol Alergol Pol 78:384-385
15. Kucia M, Reca R, Miekus K et al (2005) Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 23:879-894
16. Kucia M, Halasa M, Wysoczynski M et al (2007) Morphological and molecular characterization of novel population of CXCR4+SSEA-4+Oct-4+ very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia 21:297-303
17. Lapidot T, Sirard C, Vormoor J (1994) A cell initiation human acute myeloid leukemia after transplantation into SCID mice. Nature 367:645-648
18. Li C, Heidt DG, Dalerba P et al (2007) Identification of pancreatic cancer stem cells. Cancer Res 67:1030-1037
19. Rao CG, Chianese D, Doyle GV et al (2005) Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors. Int J Oncol 27:49-57
20. Reckamp KL, Figlin RA, Burdick MD et al (2009) CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer. BMC Cancer 9:213
21. Ricci-Vitiani L, Lombardi DG, Pilozzi E et al (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445:111-115
22. Singh SK, Clarke ID, Terasaki M et al (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63:5821-5828
23. Theodoropoulos PA, Polioudaki H, Agelaki S et al (2010) Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer. Cancer Lett 288:99-106
24. Tirino V, Camerlingo R, Franco R et al (2009) The role of CD133 in the identification and characterisation of tumour-initiating cells in non-small-cell lung cancer. Eur J Cardiothorac Surg 36:446-453
25. Tsavellas G, Huang A, McCullough T et al (2002) Flow cytometry correlates with RT-PCR for detection of spiked but not circulating colorectal cancer cells. Clin Exp Metastasis 19:495-502
26. van der Gun BT, Melchers LJ, Ruiters MH et al (2010) EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis 31:1913-1921
27. Vroling L, Lind JS, de Haas RR et al (2010) CD133+ circulating haematopoietic progenitor cells predict for response to sorafenib plus erlotinib in non-small cell lung cancer patients. Br J Cancer 102:268-275
28. Wang N, Shi L, Li H et al (2012) Detection of circulating tumor cells and tumor stem cells in patients with breast cancer by using flow cytometry: a valuable tool for diagnosis and prognosis evaluation. Tumour Biol 33:561-569
29. Went P, Vasei M, Bubendorf L et al (2006) Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers. Br J Cancer 94:128-135
30. Ye F, Li Y, Hu Y et al (2010) Stage-specific embryonic antigen 4 expression in epithelial ovarian carcinoma. Int J Gynecol Cancer 20:958-954