Sequential introduction and dosage balance of defined transcription factors affect reprogramming efficiency from pancreatic duct cells into insulin-producing cells

Biochemical and Biophysical Research Communications

Volumn 444, Issue 4, 2014, Pages 514-519

  Miyashita, Kazuyuki ^a   Miyatsuka, Takeshi ^a,b   Matsuoka, Taka Aki ^a   Sasaki, Shugo ^a   Takebe, Satomi ^a   Yasuda, Tetsuyuki ^a   Watada, Hirotaka ^b   Kaneto, Hideaki ^a   Shimomura, Iichiro ^a  

^a OSAKA UNIVERSITY   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

Author keywords

Insulin producing cells; Mafa; Neurog3; Pancreatic duct cells; Pdx1; Reprogramming

Indexed keywords

ADENOVIRUS VECTOR; INSULIN; NEUROGENIN 3; RED FLUORESCENT PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1;

ARTICLE; CELL LINE; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; IN VITRO STUDY; NUCLEAR REPROGRAMMING; PANCREAS CELL; PANCREAS DUCT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; REPORTER GENE; SCREENING;

INSULIN-PRODUCING CELLS; MAFA; NEUROG3; PANCREATIC DUCT CELLS; PDX1; REPROGRAMMING;

ADENOVIRIDAE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; GENE EXPRESSION REGULATION; GENETIC VECTORS; HOMEODOMAIN PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MAF TRANSCRIPTION FACTORS, LARGE; MICE; NERVE TISSUE PROTEINS; NUCLEAR REPROGRAMMING; PANCREATIC DUCTS; TRANS-ACTIVATORS;

EID: 84894601056     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.083     Document Type: Article

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