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Volumn 70, Issue 18, 2013, Pages 1579-1587

Pertuzumab for the treatment of human epidermal growth factor receptor type 2-positive metastatic breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

DOCETAXEL; EPITOPE; PERTUZUMAB; TRASTUZUMAB; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

EID: 84894587631     PISSN: 10792082     EISSN: 15352900     Source Type: Journal    
DOI: 10.2146/ajhp120735     Document Type: Review
Times cited : (14)

References (37)
  • 2
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science. 1987; 235:177-82.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 3
    • 84864129824 scopus 로고    scopus 로고
    • Inflammatory breast cancer: What we know and what we need to learn
    • Yamauchi H, Woodward WA, Valero V et al. Inflammatory breast cancer: what we know and what we need to learn. Oncologist. 2012; 17:891-9.
    • (2012) Oncologist , vol.17 , pp. 891-899
    • Yamauchi, H.1    Woodward, W.A.2    Valero, V.3
  • 4
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001; 344:783-92.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 5
    • 22344446208 scopus 로고    scopus 로고
    • Randomized phase II of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment; the M77001 Study Group
    • Marty M, Cognetti F, Maraninchi D et al. Randomized phase II of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment; the M77001 Study Group. J Clin Oncol. 2005; 23:4265-74.
    • (2005) J Clin Oncol , vol.23 , pp. 4265-4274
    • Marty, M.1    Cognetti, F.2    Maraninchi, D.3
  • 6
    • 33344478381 scopus 로고    scopus 로고
    • Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
    • Joensuu H, Kellokumpu-Lehtinen PL, Bono P et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med. 2006; 354:809-20.
    • (2006) N Engl J Med , vol.354 , pp. 809-820
    • Joensuu, H.1    Kellokumpu-Lehtinen, P.L.2    Bono, P.3
  • 7
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med. 2005; 353:1659-72.
    • (2005) N Engl J Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1    Procter, M.2    Leyland-Jones, B.3
  • 8
    • 33947317453 scopus 로고    scopus 로고
    • BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients
    • abstract 2
    • Slamon D, Eiermann W, Robert N et al. BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC-T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC-TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients. Breast Cancer Res Treat. 2006; 100(suppl 1):abstract 2.
    • (2006) Breast Cancer Res Treat , vol.100
    • Slamon, D.1    Eiermann, W.2    Robert, N.3
  • 9
    • 20544460650 scopus 로고    scopus 로고
    • Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: Results of a randomized trial in human epidermal growth factor 2-positive operable breast cancer
    • Buzdar AU, Ibrahim NK, Francis D et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor 2-positive operable breast cancer. J Clin Oncol. 2005; 23:3676-85.
    • (2005) J Clin Oncol , vol.23 , pp. 3676-3685
    • Buzdar, A.U.1    Ibrahim, N.K.2    Francis, D.3
  • 10
    • 78650789227 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy and concomitant trastuzumab in breast cancer: A pooled analysis of two randomized trials
    • Petrelli F, Borgonovo K, Cabiddu M et al. Neoadjuvant chemotherapy and concomitant trastuzumab in breast cancer: a pooled analysis of two randomized trials. Anticancer Drugs. 2011; 22:128.
    • (2011) Anticancer Drugs , vol.22 , pp. 128
    • Petrelli, F.1    Borgonovo, K.2    Cabiddu, M.3
  • 12
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of interceptor interactions determines signal transduction and epidermal growth factor
    • Tzahar E, Waterman H, Chen X et al. A hierarchical network of interceptor interactions determines signal transduction and epidermal growth factor. Mol Cell Biol. 1996; 16:5276-87.
    • (1996) Mol Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3
  • 14
    • 2142843806 scopus 로고    scopus 로고
    • Diversification of neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
    • Pinkas-Kramarski R, Soussan L, Waterman H et al. Diversification of neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J. 1996; 15:2452-67.
    • (1996) EMBO J , vol.15 , pp. 2452-2467
    • Pinkas-Kramarski, R.1    Soussan, L.2    Waterman, H.3
  • 15
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic breast cancer
    • Cobleigh MA, Vogel CL, Tripathy D et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic breast cancer. J Clin Oncol. 1999; 17:2639-48.
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 16
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel CL, Cobleigh MA, Tripathy D et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol. 2002; 20:719-26.
    • (2002) J Clin Oncol , vol.20 , pp. 719-726
    • Vogel, C.L.1    Cobleigh, M.A.2    Tripathy, D.3
  • 18
    • 84862894846 scopus 로고    scopus 로고
    • Pertuzumab monotherapy after trastuzumab-based treatment and subsequent reintroduction of trastuzumab: Activity and tolerability in patients with advanced human epidermal growth factor receptor 2-positive breast cancer
    • Cortés J, Fumoleau P, Bianchi GV et al. Pertuzumab monotherapy after trastuzumab-based treatment and subsequent reintroduction of trastuzumab: activity and tolerability in patients with advanced human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol. 2012; 30:1594-1600.
    • (2012) J Clin Oncol , vol.30 , pp. 1594-1600
    • Cortés, J.1    Fumoleau, P.2    Bianchi, G.V.3
  • 19
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
    • Clynes RA, Towers TL, Presta LG et al. Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets. Nat Med. 2000; 6:443-6.
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3
  • 20
    • 19044380618 scopus 로고    scopus 로고
    • Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
    • Agus DB, Akita RW, Fox WD et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell. 2002; 2:127-37.
    • (2002) Cancer Cell , vol.2 , pp. 127-137
    • Agus, D.B.1    Akita, R.W.2    Fox, W.D.3
  • 21
    • 33644600485 scopus 로고    scopus 로고
    • Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab
    • Adams CW, Allison DE, Flagella K et al. Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab. Cancer Immunol Immunother. 2006; 55:717-27.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 717-727
    • Adams, C.W.1    Allison, D.E.2    Flagella, K.3
  • 22
    • 33745343753 scopus 로고    scopus 로고
    • Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis
    • Ng CM, Lum BL, Gimenez V et al. Rationale for fixed dosing of pertuzumab in cancer patients based on population pharmacokinetic analysis. Pharm Res. 2006; 23:1275-84.
    • (2006) Pharm Res , vol.23 , pp. 1275-1284
    • Ng, C.M.1    Lum, B.L.2    Gimenez, V.3
  • 23
    • 20244378677 scopus 로고    scopus 로고
    • Phase I study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
    • Agus DB, Gordon MS, Taylor C et al. Phase I study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer. J Clin Oncol. 2005; 23:2534-43.
    • (2005) J Clin Oncol , vol.23 , pp. 2534-2543
    • Agus, D.B.1    Gordon, M.S.2    Taylor, C.3
  • 24
    • 63849224412 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of HER2-targeted rhuMAb 2C4 (pertuzumab, RO4368451) in Japanese patients with solid tumors
    • Yamamoto N, Yamada Y, Fujiwara Y et al. Phase I and pharmacokinetic study of HER2-targeted rhuMAb 2C4 (pertuzumab, RO4368451) in Japanese patients with solid tumors. Jpn J Clin Oncol. 2009; 39:260-6.
    • (2009) Jpn J Clin Oncol , vol.39 , pp. 260-266
    • Yamamoto, N.1    Yamada, Y.2    Fujiwara, Y.3
  • 25
    • 36148966170 scopus 로고    scopus 로고
    • A Phase Ib study of pertuzumab, a recombinant humanized antibody to HER2, and docetaxel in patients with advanced solid tumours
    • Attard G, Kitzen J, Blagden SP et al. A Phase Ib study of pertuzumab, a recombinant humanized antibody to HER2, and docetaxel in patients with advanced solid tumours. Br J Cancer. 2007; 97:1338-43.
    • (2007) Br J Cancer , vol.97 , pp. 1338-1343
    • Attard, G.1    Kitzen, J.2    Blagden, S.P.3
  • 27
    • 77949903478 scopus 로고    scopus 로고
    • Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
    • Baselga J, Gelmon KA, Verma S et al. Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy. J Clin Oncol. 2010; 28:1138-44.
    • (2010) J Clin Oncol , vol.28 , pp. 1138-1144
    • Baselga, J.1    Gelmon, K.A.2    Verma, S.3
  • 28
    • 52049088286 scopus 로고    scopus 로고
    • Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer
    • Portera CC, Walshe JM, Rosing DR et al. Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer. Clin Cancer Res. 2008; 14:2710-6.
    • (2008) Clin Cancer Res , vol.14 , pp. 2710-2716
    • Portera, C.C.1    Walshe, J.M.2    Rosing, D.R.3
  • 29
    • 84865748679 scopus 로고    scopus 로고
    • Drug interaction potential of trastuzumab emtansine (T-DMI) combined with pertuzumab in patients with HER2-positive metastatic breast cancer
    • Lu D, Burris HA, Wang B et al. Drug interaction potential of trastuzumab emtansine (T-DMI) combined with pertuzumab in patients with HER2-positive metastatic breast cancer. Curr Drug Metab. 2012; 13:911-22.
    • (2012) Curr Drug Metab , vol.13 , pp. 911-922
    • Lu, D.1    Burris, H.A.2    Wang, B.3
  • 30
    • 84855297353 scopus 로고    scopus 로고
    • Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): A randomised multicentre, open-label, phase 2 trial
    • Gianni L, Pienkowski T, Im YH et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol. 2012; 13:25-32.
    • (2012) Lancet Oncol , vol.13 , pp. 25-32
    • Gianni, L.1    Pienkowski, T.2    Im, Y.H.3
  • 31
    • 84862914692 scopus 로고    scopus 로고
    • Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
    • Baselga J, Cortes J, Kim SB et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med. 2012; 366:109-19.
    • (2012) N Engl J Med , vol.366 , pp. 109-119
    • Baselga, J.1    Cortes, J.2    Kim, S.B.3
  • 33
    • 84857601768 scopus 로고    scopus 로고
    • Pooled analysis of cardiac safety in patients with cancer treated with pertuzumab
    • Lenihan D, Suter T, Brammer M et al. Pooled analysis of cardiac safety in patients with cancer treated with pertuzumab. Ann Oncol. 2012; 23:791-800.
    • (2012) Ann Oncol , vol.23 , pp. 791-800
    • Lenihan, D.1    Suter, T.2    Brammer, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.