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Volumn 5, Issue 6, 2012, Pages 675-680

PI3K/AKT/mTOR signaling pathway inhibitors in proliferation of retinal pigment epithelial cells

Author keywords

Human retinal pigment epithelial cell; PI3K AKT mTORsignal pathway; Proliferativevitreoretinopathy

Indexed keywords


EID: 84894577484     PISSN: 22223959     EISSN: 22274898     Source Type: Journal    
DOI: 10.3980/j.issn.2222-3959.2012.06.05     Document Type: Article
Times cited : (37)

References (18)
  • 1
    • 0000037046 scopus 로고    scopus 로고
    • Pathogenesis of proliferative vitreoretinopathy
    • Ogden DH, Schachat AP, Murphy RP, Glaser BM, Ryan SJ, editors London: C.V. Mosby
    • Campochiaro PA. Pathogenesis of proliferative vitreoretinopathy. In: Ogden DH, Schachat AP, Murphy RP, Glaser BM, Ryan SJ, editors. Retina. London: C.V. Mosby; 2001. pp. 2221-2227.
    • (2001) Retina , pp. 2221-2227
    • Campochiaro, P.A.1
  • 3
    • 0024432577 scopus 로고
    • Evaluation of a single intravitreal injection of 5-fluorouracil in vitrectomy cases
    • Blankenship GW. Evaluation of a single intravitreal injection of 5-fluorouracil in vitrectomy cases. Graefes Arch Clin Exp Ophthalmol. 1989;227(6):565-568.
    • (1989) Graefes Arch Clin Exp Ophthalmol. , vol.227 , Issue.6 , pp. 565-568
    • Blankenship, G.W.1
  • 4
    • 0025887051 scopus 로고
    • Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy
    • Khawly JA, Saloupis P, Hatchell DL, Machemer R. Daunorubicin treatment in a refined experimental model of proliferative vitreoretinopathy. Graefes Arch Clin Exp Ophthalmol. 1991;229(5):464-467.
    • (1991) Graefes Arch Clin Exp Ophthalmol. , vol.229 , Issue.5 , pp. 464-467
    • Khawly, J.A.1    Saloupis, P.2    Hatchell, D.L.3    Machemer, R.4
  • 5
    • 0027502134 scopus 로고
    • Antiproliferative effect of retinoic acid in intravitreous silicone oil in an animal model of proliferative vitreoretinopathy
    • Araiz JJ, Refojo MF, Arroyo MH, Leong FL, Albert DM, Tolentino FI Antiproliferative effect of retinoic acid in intravitreous silicone oil in an animal model of proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 1993;34(3):522-530.
    • (1993) Invest Ophthalmol Vis Sci. , vol.34 , Issue.3 , pp. 522-530
    • Araiz, J.J.1    Refojo, M.F.2    Arroyo, M.H.3    Leong, F.L.4    Albert, D.M.5    Tolentino, F.I.6
  • 6
    • 0036707518 scopus 로고    scopus 로고
    • Effect of 2'-benzoyl-oxycinnamaldehyde on RPE cells in vitro and in an experimental proliferative vitreoretinopathy model
    • Lee JJ, Park JK, Kim YT, Kwon BM, Kang SG, Yoo YD, Yu YS, Chung H. Effect of 2'-benzoyl-oxycinnamaldehyde on RPE cells in vitro and in an experimental proliferative vitreoretinopathy model. Invest Ophthalmol Vis Sci. 2002;43(9):3117-3124.
    • (2002) Invest Ophthalmol Vis Sci. , vol.43 , Issue.9 , pp. 3117-3124
    • Lee, J.J.1    Park, J.K.2    Kim, Y.T.3    Kwon, B.M.4    Kang, S.G.5    Yoo, Y.D.6    Yu, Y.S.7    Chung, H.8
  • 8
    • 10944261058 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents
    • Rao RD, Buckner JC, Sarkaria JN Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents. Curr Cancer Drug Targets. 2004;4(8):621-635.
    • (2004) Curr Cancer Drug Targets , vol.4 , Issue.8 , pp. 621-635
    • Rao, R.D.1    Buckner, J.C.2    Sarkaria, J.N.3
  • 10
    • 13944281689 scopus 로고    scopus 로고
    • Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo
    • Kwon YS, Hong HS, Kim JC, Shin JS, Son Y. Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo. Invest Ophthalmol Vis Sci. 2005;46(2):454-460.
    • (2005) Invest Ophthalmol Vis Sci. , vol.46 , Issue.2 , pp. 454-460
    • Kwon, Y.S.1    Hong, H.S.2    Kim, J.C.3    Shin, J.S.4    Son, Y.5
  • 12
    • 0036438894 scopus 로고    scopus 로고
    • Regulation of peptide-chain elongation in mammalian cell
    • Browne GJ, Proud CG Regulation of peptide-chain elongation in mammalian cell. Eur J Biochem. 2002;269(22):5360-5368.
    • (2002) Eur J Biochem. , vol.269 , Issue.22 , pp. 5360-5368
    • Browne, G.J.1    Proud, C.G.2
  • 13
    • 8344281974 scopus 로고    scopus 로고
    • Targeting the molecular target of rapamycin (mTOR)
    • Rowinsky EK. Targeting the molecular target of rapamycin (mTOR) Curr Opin Oncol. 2004;16(6):564-575.
    • (2004) Curr Opin Oncol. , vol.16 , Issue.6 , pp. 564-575
    • Rowinsky, E.K.1
  • 14
    • 3342895823 scopus 로고    scopus 로고
    • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and rapor-independent pathway that regulates the cytoskeleton
    • Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and rapor-independent pathway that regulates the cytoskeleton. Curr Biol. 2004;14(14):1296-1302.
    • (2004) Curr Biol. , vol.14 , Issue.14 , pp. 1296-1302
    • Sarbassov, D.D.1    Ali, S.M.2    Kim, D.H.3    Guertin, D.A.4    Latek, R.R.5    Erdjument-Bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 15
    • 17844364429 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I
    • Treins C, Giorgetti-Peraldi S, Murdaca J., Monthouël-Kartmann MN, Van Obberghen E. Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I. Mol Endocrinol. 2005;19(5):1304-1317.
    • (2005) Mol Endocrinol. , vol.19 , Issue.5 , pp. 1304-1317
    • Treins, C.1    Giorgetti-Peraldi, S.2    Murdaca, J.3    Monthouël-Kartmann, M.N.4    Van Obberghen, E.5
  • 16
    • 23844547173 scopus 로고    scopus 로고
    • 15(S)-hydroxyeicosatetraenoic acid induces angiogenesis via activation of P13K-akt-mTOR-S6K1 signaling
    • Zhang B, Cao H, Rao GN 15(S)-hydroxyeicosatetraenoic acid induces angiogenesis via activation of P13K-Akt-mTOR-S6K1 signaling. Cancer Res. 2005;65(16):7283-7291.
    • (2005) Cancer Res. , vol.65 , Issue.16 , pp. 7283-7291
    • Zhang, B.1    Cao, H.2    Rao, G.N.3
  • 17
    • 0037718389 scopus 로고    scopus 로고
    • TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function
    • Schalm SS, Fingar DC, Sabatini DM, Blenis J. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function. Curr Biol. 2003;13(10):797-806.
    • (2003) Curr Biol. , vol.13 , Issue.10 , pp. 797-806
    • Schalm, S.S.1    Fingar, D.C.2    Sabatini, D.M.3    Blenis, J.4
  • 18
    • 1842852634 scopus 로고    scopus 로고
    • Pharmacogenomic profiling of the P13K/PTEN-AKT-mTOR pathway in common human tumors
    • Xu G, Zhang W, Bertram P., Zheng XF, McLeod H. Pharmacogenomic profiling of the P13K/PTEN-AKT-mTOR pathway in common human tumors. Int J Oncol. 2004;24(4):893-900.
    • (2004) Int J Oncol. , vol.24 , Issue.4 , pp. 893-900
    • Xu, G.1    Zhang, W.2    Bertram, P.3    Zheng, X.F.4    McLeod, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.