Identification of diverse natural products as falcipain-2 inhibitors through structure-based virtual screening

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 5, 2014, Pages 1261-1264

  Wang, Liyan ^a   Zhang, Shoude ^a   Zhu, Junsheng ^a   Zhu, Lili ^a   Liu, Xiaofeng ^a   Shan, Lei ^b   Huang, Jin ^a   Zhang, Weidong ^b   Li, Honglin ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antimalarial drug; Falcipain 2 inhibitors; Natural products; Virtual screening

Indexed keywords

ANTIMALARIAL DRUG; FALCIPAIN-2 INHIBITORS; NATURAL PRODUCTS; VIRTUAL SCREENING;

ANTIMALARIALS; BINDING SITES; BIOLOGICAL PRODUCTS; CYSTEINE ENDOPEPTIDASES; DRUG RESISTANCE; ENZYME INHIBITORS; MOLECULAR DOCKING SIMULATION; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84894562193     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.01.074     Document Type: Article

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