-
2
-
-
12144287320
-
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
-
Neoptolemos JP, Stocken DD, Friess H, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med. 2004; 350: 1200-10.
-
(2004)
N Engl J Med
, vol.350
, pp. 1200-1210
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Friess, H.3
-
3
-
-
78649346438
-
Adjuvant therapy in pancreatic cancer
-
Thomas A, Dajani K, Neoptolemos JP, et al. Adjuvant therapy in pancreatic cancer. Dig Dis. 2010; 28: 684-92.
-
(2010)
Dig Dis
, vol.28
, pp. 684-692
-
-
Thomas, A.1
Dajani, K.2
Neoptolemos, J.P.3
-
4
-
-
33846405332
-
Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial
-
Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA. 2007; 297: 267-77.
-
(2007)
JAMA
, vol.297
, pp. 267-277
-
-
Oettle, H.1
Post, S.2
Neuhaus, P.3
-
5
-
-
0033497862
-
Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group
-
Klinkenbijl JH, Jeekel J, Sahmoud T, et al. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg. 1999; 230: 776-82.
-
(1999)
Ann Surg
, vol.230
, pp. 776-782
-
-
Klinkenbijl, J.H.1
Jeekel, J.2
Sahmoud, T.3
-
6
-
-
49849089276
-
Adjuvant interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: a single-institution phase II study
-
Linehan DC, Tan MC, Strasberg SM, et al. Adjuvant interferon-based chemoradiation followed by gemcitabine for resected pancreatic adenocarcinoma: a single-institution phase II study. Ann Surg. 2008; 248: 145-51.
-
(2008)
Ann Surg
, vol.248
, pp. 145-151
-
-
Linehan, D.C.1
Tan, M.C.2
Strasberg, S.M.3
-
7
-
-
0037406666
-
Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma
-
Picozzi VJ, Kozarek RA, Traverso LW. Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am J Surg. 2003; 185: 476-80.
-
(2003)
Am J Surg
, vol.185
, pp. 476-480
-
-
Picozzi, V.J.1
Kozarek, R.A.2
Traverso, L.W.3
-
8
-
-
0034656872
-
Interferon-based adjuvant chemoradiation therapy improves survival after pancreaticoduodenectomy for pancreatic adenocarcinoma
-
Nukui Y, Picozzi VJ, Traverso LW. Interferon-based adjuvant chemoradiation therapy improves survival after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am J Surg. 2000; 179: 367-71.
-
(2000)
Am J Surg
, vol.179
, pp. 367-371
-
-
Nukui, Y.1
Picozzi, V.J.2
Traverso, L.W.3
-
10
-
-
3042859189
-
Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors
-
Wagner TC, Velichko S, Chesney SK, et al. Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors. Int J Cancer. 2004; 111: 32-42.
-
(2004)
Int J Cancer
, vol.111
, pp. 32-42
-
-
Wagner, T.C.1
Velichko, S.2
Chesney, S.K.3
-
11
-
-
80051905636
-
Type I interferons as radiosensitisers for pancreatic cancer
-
Morak MJ, van Koetsveld PM, Kanaar R, et al. Type I interferons as radiosensitisers for pancreatic cancer. Eur J Cancer. 2011; 47: 1938-45.
-
(2011)
Eur J Cancer
, vol.47
, pp. 1938-1945
-
-
Morak, M.J.1
van Koetsveld, P.M.2
Kanaar, R.3
-
12
-
-
12344294498
-
Human interferons alpha, beta and omega
-
Bekisz J, Schmeisser H, Hernandez J, et al. Human interferons alpha, beta and omega. Growth Factors. 2004; 22: 243-51.
-
(2004)
Growth Factors
, vol.22
, pp. 243-251
-
-
Bekisz, J.1
Schmeisser, H.2
Hernandez, J.3
-
13
-
-
0030207074
-
The type-I interferon receptor. The long and short of it
-
Domanski P, Colamonici OR. The type-I interferon receptor. The long and short of it. Cytokine Growth Factor Rev. 1996; 7: 143-51.
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 143-151
-
-
Domanski, P.1
Colamonici, O.R.2
-
14
-
-
0742322159
-
Interferons: mechanisms of action and clinical applications
-
Parmar S, Platanias LC. Interferons: mechanisms of action and clinical applications. Curr Opin Oncol. 2003; 15: 431-9.
-
(2003)
Curr Opin Oncol
, vol.15
, pp. 431-439
-
-
Parmar, S.1
Platanias, L.C.2
-
15
-
-
79960116603
-
Interferon: current status and future prospects in cancer therapy
-
Wang BX, Rahbar R, Fish EN. Interferon: current status and future prospects in cancer therapy. J Interferon Cytokine Res. 2011; 31: 545-52.
-
(2011)
J Interferon Cytokine Res
, vol.31
, pp. 545-552
-
-
Wang, B.X.1
Rahbar, R.2
Fish, E.N.3
-
16
-
-
79955675946
-
Beta-interferon for multiple sclerosis
-
Rudick RA, Goelz SE. Beta-interferon for multiple sclerosis. Exp Cell Res. 2011; 317: 1301-11.
-
(2011)
Exp Cell Res
, vol.317
, pp. 1301-1311
-
-
Rudick, R.A.1
Goelz, S.E.2
-
17
-
-
34547568178
-
Type I interferons in the treatment of pancreatic cancer: mechanisms of action and role of related receptors
-
Vitale G, van Eijck CH, van Koetsveld Ing PM, et al. Type I interferons in the treatment of pancreatic cancer: mechanisms of action and role of related receptors. Ann Surg. 2007; 246: 259-68.
-
(2007)
Ann Surg
, vol.246
, pp. 259-268
-
-
Vitale, G.1
van Eijck, C.H.2
van Koetsveld Ing, P.M.3
-
18
-
-
77956279832
-
Response of pancreatic cancer cells treated with interferon-alpha or beta and co-exposed to ionising radiation
-
Jost E, Roos WP, Kaina B, et al. Response of pancreatic cancer cells treated with interferon-alpha or beta and co-exposed to ionising radiation. Int J Radiat Biol. 2010; 86: 732-41.
-
(2010)
Int J Radiat Biol
, vol.86
, pp. 732-741
-
-
Jost, E.1
Roos, W.P.2
Kaina, B.3
-
19
-
-
84858297161
-
The expression of interferon receptor alpha/beta in human pancreatic cancer in nude mice is essential for tumor response to interferon alpha treatment
-
Saidi RF, Ahad A, Tilak J, et al. The expression of interferon receptor alpha/beta in human pancreatic cancer in nude mice is essential for tumor response to interferon alpha treatment. J Surg Res. 2012; 173: 309-13.
-
(2012)
J Surg Res
, vol.173
, pp. 309-313
-
-
Saidi, R.F.1
Ahad, A.2
Tilak, J.3
-
20
-
-
33745149996
-
Expression of interferon receptors in pancreatic cancer: identification of a novel prognostic factor
-
Saidi RF, Williams F, Silberberg B, et al. Expression of interferon receptors in pancreatic cancer: identification of a novel prognostic factor. Surgery. 2006; 139: 743-8.
-
(2006)
Surgery
, vol.139
, pp. 743-748
-
-
Saidi, R.F.1
Williams, F.2
Silberberg, B.3
-
21
-
-
0038666255
-
Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice
-
Solorzano CC, Hwang R, Baker CH, et al. Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. Clin Cancer Res. 2003; 9: 1858-67.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1858-1867
-
-
Solorzano, C.C.1
Hwang, R.2
Baker, C.H.3
-
22
-
-
79955048175
-
Synergistic antitumor effect of interferon-ss with gemcitabine in interferon-alpha-non-responsive pancreatic cancer cells
-
Tomimaru Y, Eguchi H, Wada H, et al. Synergistic antitumor effect of interferon-ss with gemcitabine in interferon-alpha-non-responsive pancreatic cancer cells. Int J Oncol. 2011; 38: 1237-43.
-
(2011)
Int J Oncol
, vol.38
, pp. 1237-1243
-
-
Tomimaru, Y.1
Eguchi, H.2
Wada, H.3
-
23
-
-
0025373614
-
Percoll density gradient centrifugation of rat pituitary tumor cells: a study of functional heterogeneity within and between tumors with respect to growth rates, prolactin production and responsiveness to the somatostatin analog SMS 201-995
-
Hofland LJ, van Koetsveld PM, Lamberts SW. Percoll density gradient centrifugation of rat pituitary tumor cells: a study of functional heterogeneity within and between tumors with respect to growth rates, prolactin production and responsiveness to the somatostatin analog SMS 201-995. Eur J Cancer. 1990; 26: 37-44.
-
(1990)
Eur J Cancer
, vol.26
, pp. 37-44
-
-
Hofland, L.J.1
van Koetsveld, P.M.2
Lamberts, S.W.3
-
24
-
-
33751518549
-
Potent inhibitory effects of type I interferons on human adrenocortical carcinoma cell growth
-
van Koetsveld PM, Vitale G, de Herder WW, et al. Potent inhibitory effects of type I interferons on human adrenocortical carcinoma cell growth. J Clin Endocrinol Metab. 2006; 91: 4537-43.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4537-4543
-
-
van Koetsveld, P.M.1
Vitale, G.2
de Herder, W.W.3
-
25
-
-
84862673869
-
The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells
-
De Martino MC, van Koetsveld PM, Feelders RA, et al. The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells. Endocr Relat Cancer. 2012; 19: 351-64.
-
(2012)
Endocr Relat Cancer
, vol.19
, pp. 351-364
-
-
De Martino, M.C.1
van Koetsveld, P.M.2
Feelders, R.A.3
-
26
-
-
31544475735
-
IFN-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro
-
Vitale G, de Herder WW, van Koetsveld PM, et al. IFN-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro. Cancer Res. 2006; 66: 554-62.
-
(2006)
Cancer Res
, vol.66
, pp. 554-562
-
-
Vitale, G.1
de Herder, W.W.2
van Koetsveld, P.M.3
-
27
-
-
0030025675
-
Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat
-
Gukovskaya AS, Perkins P, Zaninovic V, et al. Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat. Gastroenterology. 1996; 110: 875-84.
-
(1996)
Gastroenterology
, vol.110
, pp. 875-884
-
-
Gukovskaya, A.S.1
Perkins, P.2
Zaninovic, V.3
-
28
-
-
0028299340
-
The human interferon alpha/beta receptor: characterization and molecular cloning
-
Novick D, Cohen B, Rubinstein M. The human interferon alpha/beta receptor: characterization and molecular cloning. Cell. 1994; 77: 391-400.
-
(1994)
Cell
, vol.77
, pp. 391-400
-
-
Novick, D.1
Cohen, B.2
Rubinstein, M.3
-
29
-
-
0028800016
-
Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complex
-
Constantinescu SN, Croze E, Murti A, et al. Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complex. Proc Natl Acad Sci USA. 1995; 92: 10487-91.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10487-10491
-
-
Constantinescu, S.N.1
Croze, E.2
Murti, A.3
-
30
-
-
79251579661
-
Multicenter phase II trial of adjuvant therapy for resected pancreatic cancer using cisplatin, 5-fluorouracil, and interferon-alfa-2b-based chemoradiation: ACOSOG Trial Z05031
-
Picozzi VJ, Abrams RA, Decker PA, et al. Multicenter phase II trial of adjuvant therapy for resected pancreatic cancer using cisplatin, 5-fluorouracil, and interferon-alfa-2b-based chemoradiation: ACOSOG Trial Z05031. Ann Oncol. 2011; 22: 348-54.
-
(2011)
Ann Oncol
, vol.22
, pp. 348-354
-
-
Picozzi, V.J.1
Abrams, R.A.2
Decker, P.A.3
-
31
-
-
84869464216
-
Open-label, multicenter, randomized phase III trial of adjuvant chemoradiation plus interferon alfa-2b versus fluorouracil and folinic acid for patients with resected pancreatic adenocarcinoma
-
Schmidt J, Abel U, Debus J, et al. Open-label, multicenter, randomized phase III trial of adjuvant chemoradiation plus interferon alfa-2b versus fluorouracil and folinic acid for patients with resected pancreatic adenocarcinoma. J Clin Oncol. 2012; 30: 4077-83.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4077-4083
-
-
Schmidt, J.1
Abel, U.2
Debus, J.3
-
32
-
-
34547929638
-
Interferon receptor alpha/beta is associated with improved survival after adjuvant therapy in resected pancreatic cancer
-
Saidi RF, Remine SG, Jacobs MJ. Interferon receptor alpha/beta is associated with improved survival after adjuvant therapy in resected pancreatic cancer. HPB (Oxford). 2007; 9: 289-94.
-
(2007)
HPB (Oxford)
, vol.9
, pp. 289-294
-
-
Saidi, R.F.1
Remine, S.G.2
Jacobs, M.J.3
-
33
-
-
33144486461
-
Interferon receptors and the caspase cascade regulate the antitumor effects of interferons on human pancreatic cancer cell lines
-
Saidi RF, Williams F, Ng J, et al. Interferon receptors and the caspase cascade regulate the antitumor effects of interferons on human pancreatic cancer cell lines. Am J Surg. 2006; 191: 358-63.
-
(2006)
Am J Surg
, vol.191
, pp. 358-363
-
-
Saidi, R.F.1
Williams, F.2
Ng, J.3
-
34
-
-
77952214698
-
Antiproliferative properties of type I and type II interferon
-
Bekisz J, Baron S, Balinsky C, et al. Antiproliferative properties of type I and type II interferon. Pharmaceuticals (Basel). 2010; 3: 994-1015.
-
(2010)
Pharmaceuticals (Basel)
, vol.3
, pp. 994-1015
-
-
Bekisz, J.1
Baron, S.2
Balinsky, C.3
-
35
-
-
77951710240
-
Phenotype and genotype of pancreatic cancer cell lines
-
Deer EL, Gonzalez-Hernandez J, Coursen JD, et al. Phenotype and genotype of pancreatic cancer cell lines. Pancreas. 2010; 39: 425-35.
-
(2010)
Pancreas
, vol.39
, pp. 425-435
-
-
Deer, E.L.1
Gonzalez-Hernandez, J.2
Coursen, J.D.3
-
36
-
-
34548227934
-
Synergy of interferon-alpha and 5-fluorouracil in human renal cell carcinoma requires p53 activity
-
Shang D, Ito N, Watanabe J, et al. Synergy of interferon-alpha and 5-fluorouracil in human renal cell carcinoma requires p53 activity. Eur Urol. 2007; 52: 1131-9.
-
(2007)
Eur Urol
, vol.52
, pp. 1131-1139
-
-
Shang, D.1
Ito, N.2
Watanabe, J.3
-
37
-
-
0026742542
-
Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon beta
-
Johns TG, Mackay IR, Callister KA, et al. Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon beta. J Natl Cancer Inst. 1992; 84: 1185-90.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1185-1190
-
-
Johns, T.G.1
Mackay, I.R.2
Callister, K.A.3
-
38
-
-
0032417696
-
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
-
Der SD, Zhou A, Williams BR, et al. Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc Natl Acad Sci USA. 1998; 95: 15623-8.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15623-15628
-
-
Der, S.D.1
Zhou, A.2
Williams, B.R.3
-
39
-
-
84883146392
-
Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1
-
de Weerd NA, Vivian JP, Nguyen TK, et al. Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1. Nat Immunol. 2013; 14: 901-7.
-
(2013)
Nat Immunol
, vol.14
, pp. 901-907
-
-
de Weerd, N.A.1
Vivian, J.P.2
Nguyen, T.K.3
-
40
-
-
84877959168
-
Type I interferons: ancient peptides with still under-discovered anti-cancer properties
-
Caraglia M, Dicitore A, Marra M, et al. Type I interferons: ancient peptides with still under-discovered anti-cancer properties. Protein Pept Lett. 2013; 20: 412-23.
-
(2013)
Protein Pept Lett
, vol.20
, pp. 412-423
-
-
Caraglia, M.1
Dicitore, A.2
Marra, M.3
-
41
-
-
69249232214
-
Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways
-
Caraglia M, Marra M, Tagliaferri P, et al. Emerging strategies to strengthen the anti-tumour activity of type I interferons: overcoming survival pathways. Curr Cancer Drug Targets. 2009; 9: 690-704.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 690-704
-
-
Caraglia, M.1
Marra, M.2
Tagliaferri, P.3
-
42
-
-
0033779037
-
Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers
-
Buchwalder PA, Buclin T, Trinchard I, et al. Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res. 2000; 20: 857-66.
-
(2000)
J Interferon Cytokine Res
, vol.20
, pp. 857-866
-
-
Buchwalder, P.A.1
Buclin, T.2
Trinchard, I.3
-
43
-
-
84861812635
-
A novel PEGylated interferon beta-1a for multiple sclerosis: safety, pharmacology, and biology
-
Hu X, Miller L, Richman S, et al. A novel PEGylated interferon beta-1a for multiple sclerosis: safety, pharmacology, and biology. J Clin Pharmacol. 2012; 52: 798-808.
-
(2012)
J Clin Pharmacol
, vol.52
, pp. 798-808
-
-
Hu, X.1
Miller, L.2
Richman, S.3
-
44
-
-
17644380925
-
Pharmacokinetics and pharmacodynamics of PEGylated IFN-beta 1a following subcutaneous administration in monkeys
-
Mager DE, Neuteboom B, Jusko WJ. Pharmacokinetics and pharmacodynamics of PEGylated IFN-beta 1a following subcutaneous administration in monkeys. Pharm Res. 2005; 22: 58-61.
-
(2005)
Pharm Res
, vol.22
, pp. 58-61
-
-
Mager, D.E.1
Neuteboom, B.2
Jusko, W.J.3
-
45
-
-
22144465860
-
A critical function for type I interferons in cancer immunoediting
-
Dunn GP, Bruce AT, Sheehan KC, et al. A critical function for type I interferons in cancer immunoediting. Nat Immunol. 2005; 6: 722-9.
-
(2005)
Nat Immunol
, vol.6
, pp. 722-729
-
-
Dunn, G.P.1
Bruce, A.T.2
Sheehan, K.C.3
|