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Volumn 246, Issue 2, 2007, Pages 259-268

Type I interferons in the treatment of pancreatic cancer: Mechanisms of action and role of related Receptors

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON RECEPTOR; BETA1A INTERFERON; DNA FRAGMENT; RECOMBINANT ALPHA2B INTERFERON;

EID: 34547568178     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000261460.07110.f2     Document Type: Article
Times cited : (78)

References (49)
  • 1
    • 0034329115 scopus 로고    scopus 로고
    • Resected adenocarcinoma of the pancreas-616 patients: Results, outcomes, and prognostic indicators
    • Sohn T, Yeo C, Cameron J, et al. Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators. J Gastrointest Surg. 2000;4:567-579.
    • (2000) J Gastrointest Surg , vol.4 , pp. 567-579
    • Sohn, T.1    Yeo, C.2    Cameron, J.3
  • 2
    • 12144287320 scopus 로고    scopus 로고
    • A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
    • Neoptolemos JP, Stocken DD, Friess H, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med. 2004;350:1200-1210.
    • (2004) N Engl J Med , vol.350 , pp. 1200-1210
    • Neoptolemos, J.P.1    Stocken, D.D.2    Friess, H.3
  • 3
    • 0033497862 scopus 로고    scopus 로고
    • Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: Phase III trial of the EORTC gastrointestinal tract cancer cooperative group
    • Klinkenbijl JH, Jeekel J, Sahmoud T, et al. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg. 1999;230:776-782.
    • (1999) Ann Surg , vol.230 , pp. 776-782
    • Klinkenbijl, J.H.1    Jeekel, J.2    Sahmoud, T.3
  • 4
    • 0037406666 scopus 로고    scopus 로고
    • Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma
    • Picozzi VJ, Kozarek RA, Traverso LW. Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am J Surg. 2003;185:476-480.
    • (2003) Am J Surg , vol.185 , pp. 476-480
    • Picozzi, V.J.1    Kozarek, R.A.2    Traverso, L.W.3
  • 5
    • 0030993631 scopus 로고    scopus 로고
    • Synergistic antitumor effects of a combination of interferons and retinoic acid on human tumor cells in vitro and in vivo
    • Lindner DJ, Borden EC, Kalvakolanu DV. Synergistic antitumor effects of a combination of interferons and retinoic acid on human tumor cells in vitro and in vivo. Clin Cancer Res. 1997;3:931-937.
    • (1997) Clin Cancer Res , vol.3 , pp. 931-937
    • Lindner, D.J.1    Borden, E.C.2    Kalvakolanu, D.V.3
  • 6
    • 0038420703 scopus 로고    scopus 로고
    • New aspects of IFN-α/β signalling in immunity, oncogenesis and bone metabolism
    • Takaoka A, Taniguchi T. New aspects of IFN-α/β signalling in immunity, oncogenesis and bone metabolism. Cancer Sci. 2003;94:405-411.
    • (2003) Cancer Sci , vol.94 , pp. 405-411
    • Takaoka, A.1    Taniguchi, T.2
  • 7
    • 0242360790 scopus 로고    scopus 로고
    • Combination of anticancer drugs and immunotherapy
    • Mitchell MS. Combination of anticancer drugs and immunotherapy. Cancer Immunol Immunother. 2003;52:686-692.
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 686-692
    • Mitchell, M.S.1
  • 8
    • 0034453062 scopus 로고    scopus 로고
    • Slow release lanreotide in combination with interferon-α2b in the treatment of symptomatic advanced medullary thyroid carcinoma
    • Vitale G, Tagliaferri P, Caraglia M, et al. Slow release lanreotide in combination with interferon-α2b in the treatment of symptomatic advanced medullary thyroid carcinoma. J Clin Endocrinol Metab. 2000;85:983-988.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 983-988
    • Vitale, G.1    Tagliaferri, P.2    Caraglia, M.3
  • 9
    • 0035340632 scopus 로고    scopus 로고
    • Current approaches in the therapy of medullary thyroid carcinoma
    • Vitale G, Caraglia M, Ciccarelli A, et al. Current approaches in the therapy of medullary thyroid carcinoma. Cancer. 2001;91:1797-1808.
    • (2001) Cancer , vol.91 , pp. 1797-1808
    • Vitale, G.1    Caraglia, M.2    Ciccarelli, A.3
  • 10
    • 0026742542 scopus 로고
    • Antiproliferative potencies of interferons on melanoma cell lines and xenografts: Higher efficacy of interferon beta
    • Johns TG, Mackay IR, Callister KA, et al. Antiproliferative potencies of interferons on melanoma cell lines and xenografts: higher efficacy of interferon beta. J Natl Cancer Inst. 1992;84:1185-1190.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1185-1190
    • Johns, T.G.1    Mackay, I.R.2    Callister, K.A.3
  • 11
    • 0031426990 scopus 로고    scopus 로고
    • Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: Possible role of nitric oxide
    • Xie K, Bielenberg D, Huang S, et al. Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide. Clin Cancer Res. 1997;3:2283-2294.
    • (1997) Clin Cancer Res , vol.3 , pp. 2283-2294
    • Xie, K.1    Bielenberg, D.2    Huang, S.3
  • 12
    • 0032443904 scopus 로고    scopus 로고
    • Apoptosis and growth inhibition of squamous carcinoma cells treated with interferon-α, interferon-β and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21
    • Giandomenico V, Vaccari G, Fiorucci G, et al. Apoptosis and growth inhibition of squamous carcinoma cells treated with interferon-α, interferon-β and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21. Eur Cytokine Netw. 1998;9:619-631.
    • (1998) Eur Cytokine Netw , vol.9 , pp. 619-631
    • Giandomenico, V.1    Vaccari, G.2    Fiorucci, G.3
  • 13
    • 0025343857 scopus 로고
    • Growth inhibitory effects of interferon-β but not interferon-α on human glioma cells: Correlation of receptor binding 2′,5′-oligoadenylate synthetase and protein kinase activity
    • Rosenblum MG, Yung WKA, Kelleher PJ, et al. Growth inhibitory effects of interferon-β but not interferon-α on human glioma cells: correlation of receptor binding 2′,5′-oligoadenylate synthetase and protein kinase activity. J Interferon Res. 1990;10:141-151.
    • (1990) J Interferon Res , vol.10 , pp. 141-151
    • Rosenblum, M.G.1    Yung, W.K.A.2    Kelleher, P.J.3
  • 14
    • 0028556952 scopus 로고
    • The effect of α-, β- and λ-interferon on the growth of breast cancer cell lines
    • Coradini D, Biffi A, Pirronello E, et al. The effect of α-, β- and λ-interferon on the growth of breast cancer cell lines. Anticancer Res. 1994;14:1779-1784.
    • (1994) Anticancer Res , vol.14 , pp. 1779-1784
    • Coradini, D.1    Biffi, A.2    Pirronello, E.3
  • 15
    • 1542753740 scopus 로고    scopus 로고
    • Interferon-β is more potent than interferon-α in inhibition of human hepatocellular carcinoma cell growth when used alone and in combination with anticancer drugs
    • Damdinsuren B, Nagano H, Sakon M, et al. Interferon-β is more potent than interferon-α in inhibition of human hepatocellular carcinoma cell growth when used alone and in combination with anticancer drugs. Ann Surg Oncol. 2003;10:1184-1190.
    • (2003) Ann Surg Oncol , vol.10 , pp. 1184-1190
    • Damdinsuren, B.1    Nagano, H.2    Sakon, M.3
  • 16
    • 31544475735 scopus 로고    scopus 로고
    • Interferon-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro
    • Vitale G, de Herder WW, van Koetsveld PM, et al. Interferon-beta is a highly potent inhibitor of gastroenteropancreatic neuroendocrine tumor cell growth in vitro. Cancer Res. 2006;66:554-562.
    • (2006) Cancer Res , vol.66 , pp. 554-562
    • Vitale, G.1    de Herder, W.W.2    van Koetsveld, P.M.3
  • 17
    • 0033887693 scopus 로고    scopus 로고
    • Progression model for pancreatic cancer
    • Hruban RH, Goggins M, Parsons J, et al. Progression model for pancreatic cancer. Clin Cancer Res. 2000;6:2969-2972.
    • (2000) Clin Cancer Res , vol.6 , pp. 2969-2972
    • Hruban, R.H.1    Goggins, M.2    Parsons, J.3
  • 18
    • 0030023025 scopus 로고    scopus 로고
    • INK4, methylthioadenosine phosphorylase, and the α- and β-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy
    • INK4, methylthioadenosine phosphorylase, and the α- and β-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy. Cancer Res. 1996;56:1083-1090.
    • (1996) Cancer Res , vol.56 , pp. 1083-1090
    • Chen, Z.H.1    Zhang, H.2    Savarese, T.M.3
  • 19
    • 0025373614 scopus 로고
    • Percoll density gradient centrifugation of rat pituitary tumor cells: A study of functional heterogeneity within and between tumors with respect to growth rates, prolactin production and responsiveness to the somatostatin analog SMS 201-995
    • Hofland LJ, van Koetsveld PM, Lamberts SW. Percoll density gradient centrifugation of rat pituitary tumor cells: a study of functional heterogeneity within and between tumors with respect to growth rates, prolactin production and responsiveness to the somatostatin analog SMS 201-995. Eur J Cancer. 1990;26:37-44.
    • (1990) Eur J Cancer , vol.26 , pp. 37-44
    • Hofland, L.J.1    van Koetsveld, P.M.2    Lamberts, S.W.3
  • 20
    • 0036839378 scopus 로고    scopus 로고
    • Quantitative and functional expression of somatostatin receptor subtypes in human thymocytes
    • Ferone D, Pivonello R, van Hagen PM, et al. Quantitative and functional expression of somatostatin receptor subtypes in human thymocytes. Am J Physiol Endocrinol Metab. 2002;283:E1056-E1066.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Ferone, D.1    Pivonello, R.2    van Hagen, P.M.3
  • 21
    • 0031899236 scopus 로고    scopus 로고
    • Continuous venous infusion of 5-fluorouracil and interferon-alpha in pancreatic carcinoma
    • John WJ, Flett MO. Continuous venous infusion of 5-fluorouracil and interferon-alpha in pancreatic carcinoma. Am J Clin Oncol. 1998;21:147-150.
    • (1998) Am J Clin Oncol , vol.21 , pp. 147-150
    • John, W.J.1    Flett, M.O.2
  • 22
    • 0029804543 scopus 로고    scopus 로고
    • Phase II trial of prolonged continuous infusion of 5-fluorouracil and interferon-alpha in patients with advanced pancreatic cancer: Eastern Cooperative Oncology Group protocol 3292
    • Sparano J, Lipsitz S, Wadler S, et al. Phase II trial of prolonged continuous infusion of 5-fluorouracil and interferon-alpha in patients with advanced pancreatic cancer: Eastern Cooperative Oncology Group protocol 3292. Am J Clin Oncol. 1996;19:546 -551.
    • (1996) Am J Clin Oncol , vol.19 , pp. 546-551
    • Sparano, J.1    Lipsitz, S.2    Wadler, S.3
  • 23
    • 0034656872 scopus 로고    scopus 로고
    • Interferon-based adjuvant chemoradiation therapy improves survival after pancreaticoduodenectomy for pancreatic adenocarcinoma
    • Nukui Y, Picozzi VJ, Traverso LW. Interferon-based adjuvant chemoradiation therapy improves survival after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am J Surg. 2000;179:367-371.
    • (2000) Am J Surg , vol.179 , pp. 367-371
    • Nukui, Y.1    Picozzi, V.J.2    Traverso, L.W.3
  • 24
    • 0032400789 scopus 로고    scopus 로고
    • A phase II pilot trial of 13-cis retinoic acid and interferon-α in patients with advanced pancreatic carcinoma
    • Brembeck FH, Schoppmeyer K, Leupold U, et al. A phase II pilot trial of 13-cis retinoic acid and interferon-α in patients with advanced pancreatic carcinoma. Cancer. 1998;83:2317-2323.
    • (1998) Cancer , vol.83 , pp. 2317-2323
    • Brembeck, F.H.1    Schoppmeyer, K.2    Leupold, U.3
  • 25
    • 0031022310 scopus 로고    scopus 로고
    • Treatment of advanced pancreatic adenocarcinoma with 5-FU, leucovorin, interferon-alpha-2b, and cisplatin
    • Sporn JR, Buzaid AC, Slater D, et al. Treatment of advanced pancreatic adenocarcinoma with 5-FU, leucovorin, interferon-alpha-2b, and cisplatin. Am J Clin Oncol. 1997;20:81-83.
    • (1997) Am J Clin Oncol , vol.20 , pp. 81-83
    • Sporn, J.R.1    Buzaid, A.C.2    Slater, D.3
  • 26
    • 0028891804 scopus 로고
    • Treatment of advanced pancreatic cancer with 5-fluorouracil, folinic acid and interferon alpha-2A: Results of a phase II trial
    • Bernhard H, Jager-Arand E, Bernhard G, et al. Treatment of advanced pancreatic cancer with 5-fluorouracil, folinic acid and interferon alpha-2A: results of a phase II trial. Br J Cancer. 1995;71:102-105.
    • (1995) Br J Cancer , vol.71 , pp. 102-105
    • Bernhard, H.1    Jager-Arand, E.2    Bernhard, G.3
  • 27
    • 0035132925 scopus 로고    scopus 로고
    • Intact nitric oxide synthase II gene is required for interferon-β-mediated suppression of growth and metastasis of pancreatic adenocarcinoma
    • Wang B, Xiong Q, Shi Q, et al. Intact nitric oxide synthase II gene is required for interferon-β-mediated suppression of growth and metastasis of pancreatic adenocarcinoma. Cancer Res. 2001;61:71-75.
    • (2001) Cancer Res , vol.61 , pp. 71-75
    • Wang, B.1    Xiong, Q.2    Shi, Q.3
  • 28
    • 23044458539 scopus 로고    scopus 로고
    • Growth inhibition of human pancreatic cancer cells by human interferon-β gene combined with gemcitabine
    • Endou M, Mizuno M, Nagata T, et al. Growth inhibition of human pancreatic cancer cells by human interferon-β gene combined with gemcitabine. Int J Mol Med. 2005;15:277-283.
    • (2005) Int J Mol Med , vol.15 , pp. 277-283
    • Endou, M.1    Mizuno, M.2    Nagata, T.3
  • 29
    • 0033827220 scopus 로고    scopus 로고
    • Combined chemotherapy, radiotherapy, and immunotherapy for pancreatic carcinoma: A case report
    • Busch M, Wilkowski R, Schaffer M, et al. Combined chemotherapy, radiotherapy, and immunotherapy for pancreatic carcinoma: a case report. Adv Ther. 2000;17:133-139.
    • (2000) Adv Ther , vol.17 , pp. 133-139
    • Busch, M.1    Wilkowski, R.2    Schaffer, M.3
  • 30
    • 0031814703 scopus 로고    scopus 로고
    • Advanced carcinoma of the pancreas: Phase II study of combined chemotherapy, beta-interferon, and retinoids
    • Recchia F, Sica G, Casucci D, et al. Advanced carcinoma of the pancreas: phase II study of combined chemotherapy, beta-interferon, and retinoids. Am J Clin Oncol. 1998;21:275-279.
    • (1998) Am J Clin Oncol , vol.21 , pp. 275-279
    • Recchia, F.1    Sica, G.2    Casucci, D.3
  • 31
    • 33144486461 scopus 로고    scopus 로고
    • Interferon receptors and the caspase cascade regulate the antitumor effects of interferons on human pancreatic cancer cell lines
    • Saidi RF, Williams F, Ng F, et al. Interferon receptors and the caspase cascade regulate the antitumor effects of interferons on human pancreatic cancer cell lines. Am J Surg. 2006;191:358-363.
    • (2006) Am J Surg , vol.191 , pp. 358-363
    • Saidi, R.F.1    Williams, F.2    Ng, F.3
  • 32
    • 33748575911 scopus 로고    scopus 로고
    • Expression of type I interferon receptor as a predictor of clinical response to interferon-α therapy of gastrointestinal cancers
    • Ota H, Nagano H, Doki Y, et al. Expression of type I interferon receptor as a predictor of clinical response to interferon-α therapy of gastrointestinal cancers. Oncol Rep. 2006;16:249-255.
    • (2006) Oncol Rep , vol.16 , pp. 249-255
    • Ota, H.1    Nagano, H.2    Doki, Y.3
  • 33
    • 33745149996 scopus 로고    scopus 로고
    • Expression of interferon receptors in pancreatic cancer: Identification of a novel prognostic factor
    • Saidi RF, Williams F, Silberberg B, et al. Expression of interferon receptors in pancreatic cancer: identification of a novel prognostic factor. Surgery. 2006;139:743-748.
    • (2006) Surgery , vol.139 , pp. 743-748
    • Saidi, R.F.1    Williams, F.2    Silberberg, B.3
  • 34
    • 0032692405 scopus 로고    scopus 로고
    • The type I interferon receptor: Structure, function, and evolution of a family business
    • Mogensen KE, Lewerenz M, Reboul J, et al. The type I interferon receptor: structure, function, and evolution of a family business. J Interferon Cytokine Res. 1999;19:1069-1098.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 1069-1098
    • Mogensen, K.E.1    Lewerenz, M.2    Reboul, J.3
  • 35
    • 0036399552 scopus 로고    scopus 로고
    • Interferon-α/β- receptor interactions: A complex story unfolding
    • Deonarain R, Chan DCM, Platanias LC, et al. Interferon-α/β- receptor interactions: a complex story unfolding. Curr Pharm Des. 2002;8:2131-2137.
    • (2002) Curr Pharm Des , vol.8 , pp. 2131-2137
    • Deonarain, R.1    Chan, D.C.M.2    Platanias, L.C.3
  • 36
    • 0029148972 scopus 로고
    • Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signalling
    • Domanski P, Witte M, Kellum M, et al. Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signalling. J Biol Chem. 1995;270:21606-21611.
    • (1995) J Biol Chem , vol.270 , pp. 21606-21611
    • Domanski, P.1    Witte, M.2    Kellum, M.3
  • 37
    • 0030207074 scopus 로고    scopus 로고
    • The type-I interferon receptor: The long and short of it
    • Domanski P, Colamonici OR. The type-I interferon receptor: the long and short of it. Cytokine Growth Factor Rev. 1996;7:143-151.
    • (1996) Cytokine Growth Factor Rev , vol.7 , pp. 143-151
    • Domanski, P.1    Colamonici, O.R.2
  • 38
    • 0030994132 scopus 로고    scopus 로고
    • The interferon receptors
    • Pestka S. The interferon receptors. Semin Oncol. 1997;24(suppl 9):18-40.
    • (1997) Semin Oncol , vol.24 , Issue.SUPPL. 9 , pp. 18-40
    • Pestka, S.1
  • 39
    • 0029052176 scopus 로고
    • Ligand-induced association of the type I interferon receptor components
    • Cohen B, Novick D, Barak S, et al. Ligand-induced association of the type I interferon receptor components. Mol Cell Biol. 1995;15:4208-4214.
    • (1995) Mol Cell Biol , vol.15 , pp. 4208-4214
    • Cohen, B.1    Novick, D.2    Barak, S.3
  • 40
    • 0030977225 scopus 로고    scopus 로고
    • The short form of the interferon alpha/beta receptor chain 2 acts as a dominant negative for type I interferon action
    • Pfeffer LM, Basu L, Pfeffer SR, et al. The short form of the interferon alpha/beta receptor chain 2 acts as a dominant negative for type I interferon action. J Biol Chem. 1997;272:11002-11005.
    • (1997) J Biol Chem , vol.272 , pp. 11002-11005
    • Pfeffer, L.M.1    Basu, L.2    Pfeffer, S.R.3
  • 41
    • 0035863894 scopus 로고    scopus 로고
    • The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties
    • Hardy MP, Owczarek CM, Trajanovska S, et al. The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties. Blood. 2001;97:473-482.
    • (2001) Blood , vol.97 , pp. 473-482
    • Hardy, M.P.1    Owczarek, C.M.2    Trajanovska, S.3
  • 42
    • 1342309317 scopus 로고    scopus 로고
    • Formation of human IFN-beta complex with the soluble type I interferon receptor IFNAR-2 leads to enhanced IFN stability, pharmacokinetics, and antitumor activity in xenografted SCID mice
    • McKenna SD, Vergilis K, Arulanandam AR, et al. Formation of human IFN-beta complex with the soluble type I interferon receptor IFNAR-2 leads to enhanced IFN stability, pharmacokinetics, and antitumor activity in xenografted SCID mice. J Interferon Cytokine Res. 2004;24:119-129.
    • (2004) J Interferon Cytokine Res , vol.24 , pp. 119-129
    • McKenna, S.D.1    Vergilis, K.2    Arulanandam, A.R.3
  • 43
    • 0033779037 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers
    • Buchwalder PA, Buclin T, Trinchard I, et al. Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res. 2000;20:857-866.
    • (2000) J Interferon Cytokine Res , vol.20 , pp. 857-866
    • Buchwalder, P.A.1    Buclin, T.2    Trinchard, I.3
  • 44
    • 0029912760 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers
    • Salmon P, Le Cotonnec JY, Galazka A, et al. Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers. J Interferon Cytokine Res. 1996;16:759-764.
    • (1996) J Interferon Cytokine Res , vol.16 , pp. 759-764
    • Salmon, P.1    Le Cotonnec, J.Y.2    Galazka, A.3
  • 45
    • 3042859189 scopus 로고    scopus 로고
    • Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors
    • Wagner TC, Velichko S, Chesney SK, et al. Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors. Int J Cancer. 2004;111:32-42.
    • (2004) Int J Cancer , vol.111 , pp. 32-42
    • Wagner, T.C.1    Velichko, S.2    Chesney, S.K.3
  • 46
    • 85070037893 scopus 로고    scopus 로고
    • Differential receptor subunit affinities of type I interferons govern differential signal activation
    • Epub ahead of print
    • Jaks E, Gavutis M, Uze G, et al. Differential receptor subunit affinities of type I interferons govern differential signal activation. J Mol Biol. 2006;18 (Epub ahead of print).
    • (2006) J Mol Biol , pp. 18
    • Jaks, E.1    Gavutis, M.2    Uze, G.3
  • 47
    • 0031566032 scopus 로고    scopus 로고
    • The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution
    • Klaus W, Gsell B, Labhardt AM, et al. The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution. J Mol Biol. 1997;274:661-675.
    • (1997) J Mol Biol , vol.274 , pp. 661-675
    • Klaus, W.1    Gsell, B.2    Labhardt, A.M.3
  • 48
    • 0030704730 scopus 로고    scopus 로고
    • The crystal structure of human interferon beta at 2. 2-A resolution
    • Karpusas M, Nolte M, Benton CB, et al. The crystal structure of human interferon beta at 2. 2-A resolution. Proc Natl Acad Sci USA. 1997;94:11813-11818.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11813-11818
    • Karpusas, M.1    Nolte, M.2    Benton, C.B.3
  • 49
    • 0032727032 scopus 로고    scopus 로고
    • Signaling pathways activated by interferons
    • Platanias LC, Fish EN. Signaling pathways activated by interferons. Exp Hematol. 1999;27:1583-1592.
    • (1999) Exp Hematol , vol.27 , pp. 1583-1592
    • Platanias, L.C.1    Fish, E.N.2


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