Why breeding values estimated using familial data should not be used for genome-wide association studies

G3: Genes, Genomes, Genetics

Volumn 4, Issue 2, 2014, Pages 341-347

  Ekine, Chinyere C ^a,c   Rowe, Suzanne J ^a,d   Bishop, Stephen C ^a   de Koning, Dirk Jan ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^c UNIVERSITY OF ALBERTA   (Canada)

^d INVERMAY AGRICULTURAL CENTRE   (New Zealand)

Author keywords

Family structure; Genome wide association; Statistical power; Type I error

Indexed keywords

ARTICLE; BREEDING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPING TECHNIQUE; HERITABILITY; HUMAN; NONHUMAN; PEDIGREE; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; SWINE;

FAMILY STRUCTURE; GENOME-WIDE ASSOCIATION; STATISTICAL POWER; TYPE I ERROR;

ANIMALS; ANIMALS, DOMESTIC; BREEDING; DATA INTERPRETATION, STATISTICAL; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MODELS, GENETIC; PEDIGREE; QUANTITATIVE TRAIT LOCI; SWINE;

EID: 84894530273     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.113.008706     Document Type: Article

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