Impact of airborne particle size, acoustic airflow and breathing pattern on delivery of nebulized antibiotic into the maxillary sinuses using a realistic human nasal replica

Pharmaceutical Research

Volumn 31, Issue 9, 2014, Pages 2335-2343

  Leclerc, Lara ^a,b,c   Pourchez, Jérémie ^b,c   Aubert, Gérald ^d   Leguellec, Sandrine ^e   Vecellio, Laurent ^e   Cottier, Michèle ^a,c   Durand, Marc ^a,c,f  

^a Jean Monnet University   (France)

^b ECOLE DES MINES DE SAINT ETIENNE   (France)

^c SFR IFRESIS   (France)

^d UNIVERSITY HOSPITAL OF SAINT ETIENNE   (France)

^e UNIVERSITÉ DE TOURS   (France)

^f Emile Roux Hospital AP HP   (France)

Author keywords

aerosol therapy; drug deposition; maxillary sinuses; nasal replica

Indexed keywords

AEROSOL; ANTIINFECTIVE AGENT; GENTAMICIN;

ACOUSTICS; ADULT; AEROSOL; ANATOMY AND HISTOLOGY; AUDIOVISUAL EQUIPMENT; BREATHING; CHEMISTRY; DRUG DELIVERY SYSTEM; EQUIPMENT DESIGN; HUMAN; INTRANASAL DRUG ADMINISTRATION; MALE; MAXILLARY SINUS; NEBULIZER; NOSE; PARTICLE SIZE; PHYSIOLOGY;

ACOUSTICS; ADMINISTRATION, INTRANASAL; ADULT; AEROSOLS; ANTI-BACTERIAL AGENTS; DRUG DELIVERY SYSTEMS; EQUIPMENT DESIGN; GENTAMICINS; HUMANS; MALE; MAXILLARY SINUS; MODELS, ANATOMIC; NEBULIZERS AND VAPORIZERS; NOSE; PARTICLE SIZE; RESPIRATION;

EID: 84894525851     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1330-6     Document Type: Article

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