Expression and significance of lysyl oxidase-like 1 and fibulin-5 in the cardinal ligament tissue of patients with pelvic floor dysfunction

Journal of Biomedical Research

Volumn 27, Issue 1, 2013, Pages 23-28

  Zhou, Yang ^a   Ling, Ouyang ^a   Bo, Li ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Fibulin 5; Lysyl oxidase like 1; Pelvic floor dysfunction; Pelvic organ prolapse; Stress urinary incontinence

Indexed keywords

FIBULIN 5; LYSYL OXIDASE LIKE 1; PROTEIN LYSINE 6 OXIDASE; UNCLASSIFIED DRUG;

ABDOMINAL HYSTERECTOMY; ADULT; ARTICLE; CARDINAL LIGAMENT; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIGAMENT; MAJOR CLINICAL STUDY; PATHOGENESIS; PELVIC FLOOR DISORDER; PROTEIN EXPRESSION; STRESS INCONTINENCE; VAGINAL DELIVERY;

EID: 84894495006     PISSN: 16748301     EISSN: None     Source Type: Journal    
DOI: 10.7555/JBR.27.20110142     Document Type: Article

References (22)

1. Goepel C. Differential elastin and tenascin immunolabeling in the uterosacral ligaments in postpost-menopausal women with and without pelvic organ prolapse. Acta Histochem 2008; 110: 204-9.
2. Drewes PG, Yanagisawa H, Starcher B, Hornstra I, Csiszar K, Marinis SI, et al. Pelvic organ prolapse in fibulin-5 knockout mice:pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Am J Pathol 2007; 170: 578-89.
3. Tremollieres F. Connective tissue and prolapse genesis. Gynecol Obstet Fertil 2010; 38: 388-93.
4. Jung HJ, Jeon MJ, Yim GW, Kim SK, Choi JR, Bai SW. Changes in expression of fibulin-5 and lysyl oxidase-like 1 associated with pelvic organ prolapse. Eur J Obstet Gynecol Reprod Biol 2009; 145: 117-22.
5. Behmoaras J, Slove S, Seve S, Vranckx R, Sommer P, Jacob MP. Differential expression of lysyl oxidases LOXL1 and LOX during growth and aging suggests specific roles in elastin and collagen fiber remodeling in rat aorta. Rejuvenation Res 2008; 11: 883-9.
6. Hirai M, Ohbayashi T, Horiguchi M, Okawa K, Hagiwara A, Chien KR, et al. Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. J Cell Biol 2007; 176: 1061-71.
7. Yanagisawa H, Davis EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson JA, et al. Fibulin-5 is an elastinbinding protein essential for elastic fibre development in vivo. Nature 2002; 415: 168-71.
8. Bump RC, Mattiasson A, BøK, Brubaker LP, DeLancey JO, Klarskov P, et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol 1996; 175: 10-7.
9. Kasturi S, Lowman JK, Kelvin FM, Akisik FM, Terry CL, Hale DS. Pelvic magnetic resonance imaging for assessment of the efficacy of the Prolift system for pelvic organ prolapse. Am J Obstet Gynecol 2010; 203: 504.e1-5.
10. Weber AM, Buchsbaum GM, Chen B, Clark AL, Damaser MS, Daneshgari F, et al. Basic science and translational research in female pelvic floor disorders: proceedings of an NIH-sponsored meeting. Neurourol Urodyn 2004; 23: 288-301.
11. Pierce LM, Baumann S, Rankin MR, Wasserman RM, Biaggi A, Kuehl TJ, et al. Levator ani muscle and connective tissue changes associated with pelvic organ prolapse,parity,and aging in the squirrel monkey: a histologic study. Am J Obstet Gynecol 2007; 197: 60-9.
12. Goepel C. Differential elastin and tenascin immunolabeling in the uterosacral ligaments in postmenopausal women with and without pelvic organ prolapse. Acta Histochem 2008; 110: 204-9.
13. Chen B, Wen Y, Polan ML. Elastolytic activity in women with stress urinary incontinence and pelvic organ prolapse. Neurourol Urodyn 2004; 23: 119-26.
14. Karam JA, Vazquez DV, Lin VK, Zimmern PE. Elastin expression and elastic fibre width in the anterior vaginal wall of postmenopausal women with and without prolapse. BJU Int 2007; 100: 346-50.
15. Kagan HM, Li W. Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem 2003; 88: 660-72.
16. Katsuta Y, Ogura Y, Iriyama S, Goetinck PF, Klement JF, Uitto J, et al. Fibulin-5 accelerates elastic fibre assembly in human skin fibroblasts. Exp Dermatol 2008: 837-42.
17. Nakamura T, Lozano PR, Ikeda Y, Iwanaga Y, Hinek A, Minamisawa S, et al. Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature 2002; 415: 171-5.
18. Drewes PG, Yanagisawa H, Starcher B, Hornstra I, Csiszar K, Marinis SI, et al. Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Am J Pathol 2007; 170: 578-89.
19. Lee UJ, Gustilo-Ashby AM, Daneshgari F, Kuang M, Vurbic D, Lin DL, et al. Lower urogenital tract anatomical and functional phenotype in lysyl oxidase like1 knockout mice resembles female pelvic floor dysfunction in humans. Am J Physiol Renal Physiol 2008; 295: F545-55.
20. Mäki JM, Sormunen R, Lippo S, Kaarteenaho-Wiik R, Soininen R, Myllyharju J. Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in varioustissues. Am J Pathol 2005; 167: 927-36.
21. Liu G, Daneshgari F, Lin D, Lin D, Lee U, Li T, et al. Bladder and urethral function in pelvic organ prolapsed lysyl oxidase like-1 knockout mice. BJU Int 2007; 100: 414-8.
22. Kobak W, Lu J, Hardart A. Expression of lysyl oxidase and transforming growth factor beta-2 in women with severe pelvic organ prolapse. J Reprod Med 2005 Nov; 50: 827-31.