A new gel formulation of topical cysteamine for the treatment of corneal cystine crystals in cystinosis: The Cystadrops OCT-1 study

Molecular Genetics and Metabolism

Volumn 111, Issue 3, 2014, Pages 314-320

  Labbé, Antoine ^a,b   Baudouin, Christophe ^a,b   Deschênes, Georges ^d   Loirat, Chantal ^d   Charbit, Marina ^c   Guest, Geneviève ^c   Niaudet, Patrick ^c  

^a CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

^b LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

^d HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Cornea; Cysteamine hydrochloride; Cystinosis; Gel formulation

Indexed keywords

CYSTINE; EYE DROPS; MERCAPTAMINE; GEL;

ADOLESCENT; ADOLESCENT DISEASE; ADULT; ARTICLE; BLURRED VISION; BURN; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORNEA CYSTINE CRYSTAL; CORNEA DISEASE; CRYSTAL; CYSTINOSIS; DENSITY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG FORMULATION; DRUG MONITORING; DRUG SAFETY; DRUG STORAGE; FEMALE; FOLLOW UP; GEL; HUMAN; INTRAOCULAR PRESSURE; MALE; MEDICATION COMPLIANCE; NEPHROPATHIC CYSTINOSIS; OPEN STUDY; PAIN ASSESSMENT; PAIN INTENSITY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHOTOPHOBIA; RISK ASSESSMENT; ROOM TEMPERATURE; SLIT LAMP; TOPICAL TREATMENT; ADMINISTRATION AND DOSAGE; CHEMISTRY; CORNEA; CRYSTALLIZATION; METABOLISM; PATHOLOGY; TOPICAL DRUG ADMINISTRATION; YOUNG ADULT;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; CHILD; CORNEA; CRYSTALLIZATION; CYSTEAMINE; CYSTINE; CYSTINOSIS; FEMALE; GELS; HUMANS; MALE; OPHTHALMIC SOLUTIONS; YOUNG ADULT;

EID: 84894487574     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2013.12.298     Document Type: Article

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