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Volumn 16, Issue 4, 2014, Pages

Hepatitis E virus: Current concepts and future perspectives

Author keywords

Chronic liver disease; Epidemiology; Hepatitis; Hepatitis E; Zoonosis

Indexed keywords

IMMUNOGLOBULIN G;

EID: 84894483871     PISSN: 15233847     EISSN: 15343146     Source Type: Journal    
DOI: 10.1007/s11908-014-0399-8     Document Type: Review
Times cited : (21)

References (107)
  • 1
    • 0025955282 scopus 로고
    • Hepatitis E virus (HEV): Molecular cloning and sequencing of the full-length viral genome
    • Tam AW, Smith MM, Guerra ME, Huang CC, Bradley DW, Fry KE, et al. Hepatitis E virus (HEV): molecular cloning and sequencing of the full-length viral genome. Virology. 1991;185:120-31.
    • (1991) Virology , vol.185 , pp. 120-131
    • Tam, A.W.1    Smith, M.M.2    Guerra, M.E.3    Huang, C.C.4    Bradley, D.W.5    Fry, K.E.6
  • 2
    • 0026655694 scopus 로고
    • Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: Delineation of an additional group of positive-strand RNA plant and animal viruses
    • Koonin EV, Gorbalenya AE, Purdy MA, Rozanov MN, Reyes GR, Bradley DW. Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: delineation of an additional group of positive-strand RNA plant and animal viruses. Proc Natl Acad Sci U S A. 1992;89:8259-63.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 8259-8263
    • Koonin, E.V.1    Gorbalenya, A.E.2    Purdy, M.A.3    Rozanov, M.N.4    Reyes, G.R.5    Bradley, D.W.6
  • 3
    • 0025269678 scopus 로고
    • Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis
    • Reyes GR, Purdy MA, Kim JP, Luk KC, Young LM, Fry KE, et al. Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis. Science. 1990;247:1335-9.
    • (1990) Science , vol.247 , pp. 1335-1339
    • Reyes, G.R.1    Purdy, M.A.2    Kim, J.P.3    Luk, K.C.4    Young, L.M.5    Fry, K.E.6
  • 4
    • 33744939709 scopus 로고    scopus 로고
    • A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus
    • DOI 10.1128/JVI.00046-06
    • Graff J, Torian U, Nguyen H, Emerson SU. A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus. J Virol. 2006;80:5919-26. (Pubitemid 43849169)
    • (2006) Journal of Virology , vol.80 , Issue.12 , pp. 5919-5926
    • Graff, J.1    Torian, U.2    Nguyen, H.3    Emerson, S.U.4
  • 5
    • 69149100932 scopus 로고    scopus 로고
    • Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure
    • Yamashita T, Mori Y, Miyazaki N, Cheng RH, Yoshimura M, Unno H, et al. Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure. Proc Natl Acad Sci U S A. 2009;106:12986-91.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12986-12991
    • Yamashita, T.1    Mori, Y.2    Miyazaki, N.3    Cheng, R.H.4    Yoshimura, M.5    Unno, H.6
  • 6
    • 13544267412 scopus 로고    scopus 로고
    • Mutational analysis of essential interactions involved in the assembly of hepatitis E virus capsid
    • DOI 10.1074/jbc.M410361200
    • .• Li SW, Zhang J, He ZQ, Gu Y, Liu RS, Lin J, et al. Mutational analysis of essential interactions involved in the assembly of hepatitis E virus capsid. J Biol Chem. 2005;280:3400-6. This is the first structural and funtional study on hepatitis E virus using crystallography, giving insight on virus-host interactions. (Pubitemid 40223803)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.5 , pp. 3400-3406
    • Li, S.-W.1    Zhang, J.2    He, Z.-Q.3    Gu, Y.4    Liu, R.-S.5    Lin, J.6    Chen, Y.-X.7    Ng, M.-H.8    Xia, N.-S.9
  • 7
    • 72849138163 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are required for cellular binding of the hepatitis E virus ORF2 capsid protein and for viral infection
    • Kalia M, Chandra V, Rahman SA, Sehgal D, Jameel S. Heparan sulfate proteoglycans are required for cellular binding of the hepatitis E virus ORF2 capsid protein and for viral infection. J Virol. 2009;83:12714-24.
    • (2009) J Virol , vol.83 , pp. 12714-12724
    • Kalia, M.1    Chandra, V.2    Rahman, S.A.3    Sehgal, D.4    Jameel, S.5
  • 8
    • 79960020875 scopus 로고    scopus 로고
    • Structural basis for the neutralization and genotype specificity of hepatitis E virus
    • Tang X, Yang C, Gu Y, Song C, Zhang X, Wang Y, et al. Structural basis for the neutralization and genotype specificity of hepatitis E virus. Proc Natl Acad Sci U S A. 2011;108:10266-71.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10266-10271
    • Tang, X.1    Yang, C.2    Gu, Y.3    Song, C.4    Zhang, X.5    Wang, Y.6
  • 9
    • 84865756039 scopus 로고    scopus 로고
    • Hepatitis E virus: Neutralizing sites, diagnosis, and protective immunity
    • Zhang J, Li SW, Wu T, Zhao Q, Ng MH, Xia NS. Hepatitis E virus: neutralizing sites, diagnosis, and protective immunity. Rev Med Virol. 2012;22:339-49.
    • (2012) Rev Med Virol , vol.22 , pp. 339-349
    • Zhang, J.1    Li, S.W.2    Wu, T.3    Zhao, Q.4    Ng, M.H.5    Xia, N.S.6
  • 10
    • 0035975619 scopus 로고    scopus 로고
    • Identification and characterization of the neutralization epitope(s) of the hepatitis E virus
    • DOI 10.1006/viro.2001.1093
    • Meng J, Dai X, Chang JC, Lopareva E, Pillot J, Fields HA, et al. Identification and characterization of the neutralization epitope(s) of the hepatitis E virus. Virology. 2001;288:203-11. (Pubitemid 32929900)
    • (2001) Virology , vol.288 , Issue.2 , pp. 203-211
    • Meng, J.1    Dai, X.2    Chang, J.C.3    Lopareva, E.4    Pillot, J.5    Fields, H.A.6    Khudyakov, Y.E.7
  • 11
    • 0035834641 scopus 로고    scopus 로고
    • The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK
    • Korkaya H, Jameel S, Gupta D, Tyagi S, Kumar R, Zafrullah M, et al. The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK. J Biol Chem. 2001;276:42389-400.
    • (2001) J Biol Chem , vol.276 , pp. 42389-42400
    • Korkaya, H.1    Jameel, S.2    Gupta, D.3    Tyagi, S.4    Kumar, R.5    Zafrullah, M.6
  • 12
    • 47049088602 scopus 로고    scopus 로고
    • The hepatitis E virus ORF3 protein modulates epidermal growth factor receptor trafficking, STAT3 translocation, and the acute-phase response
    • DOI 10.1128/JVI.00403-08
    • Chandra V, Kar-Roy A, Kumari S, Mayor S, Jameel S. The hepatitis E virus ORF3 protein modulates epidermal growth factor receptor trafficking, STAT3 translocation, and the acute-phase response. J Virol. 2008;82:7100-10. (Pubitemid 351977728)
    • (2008) Journal of Virology , vol.82 , Issue.14 , pp. 7100-7110
    • Chandra, V.1    Kar-Roy, A.2    Kumari, S.3    Mayor, S.4    Jameel, S.5
  • 13
    • 3142581465 scopus 로고    scopus 로고
    • The hepatitis E virus open reading frame 3 protein activates ERK through binding and inhibition of the MAPK phosphatase
    • DOI 10.1074/jbc.M400457200
    • Kar-Roy A, Korkaya H, Oberoi R, Lal SK, Jameel S. The hepatitis E virus open reading frame 3 protein activates ERK through binding and inhibition of the MAPK phosphatase. J Biol Chem. 2004;279:28345-57. (Pubitemid 38900114)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.27 , pp. 28345-28357
    • Kar-Roy, A.1    Korkaya, H.2    Oberoi, R.3    Lal, S.K.4    Jameel, S.5
  • 14
    • 79251485981 scopus 로고    scopus 로고
    • A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells
    • Nagashima S, Takahashi M, Jirintai, Tanaka T, Yamada K, Nishizawa T, et al. A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells. J Gen Virol. 2011;92:269-78.
    • (2011) J Gen Virol , vol.92 , pp. 269-278
    • Nagashima, S.1    Takahashi, M.2    Jirintai3    Tanaka, T.4    Yamada, K.5    Nishizawa, T.6
  • 15
    • 78149457207 scopus 로고    scopus 로고
    • Profile of acute infectious markers in sporadic hepatitis E
    • Huang S, Zhang X, Jiang H, Yan Q, Ai X, Wang Y, et al. Profile of acute infectious markers in sporadic hepatitis E. PLoS One. 2010;5:e13560.
    • (2010) PLoS One , vol.5
    • Huang, S.1    Zhang, X.2    Jiang, H.3    Yan, Q.4    Ai, X.5    Wang, Y.6
  • 16
    • 84884532518 scopus 로고    scopus 로고
    • Role of hepatitis E virus antigen in confirming active viral replication in patients with acute viral hepatitis E infection
    • Gupta E, Pandey P, Pandey S, Sharma MK, Sarin SK. Role of hepatitis E virus antigen in confirming active viral replication in patients with acute viral hepatitis E infection. J Clin Virol 2013.
    • (2013) J Clin Virol
    • Gupta, E.1    Pandey, P.2    Pandey, S.3    Sharma, M.K.4    Sarin, S.K.5
  • 17
    • 77955962476 scopus 로고    scopus 로고
    • Characteristics of autochthonous hepatitis E virus infection in solid-organ transplant recipients in France
    • Legrand-Abravanel F, Kamar N, Sandres-Saune K, Garrouste C, Dubois M, Mansuy JM, et al. Characteristics of autochthonous hepatitis E virus infection in solid-organ transplant recipients in France. J Infect Dis. 2010;202:835-44.
    • (2010) J Infect Dis , vol.202 , pp. 835-844
    • Legrand-Abravanel, F.1    Kamar, N.2    Sandres-Saune, K.3    Garrouste, C.4    Dubois, M.5    Mansuy, J.M.6
  • 20
    • 54049157144 scopus 로고    scopus 로고
    • Hepatitis E: An emerging infection in developed countries
    • Dalton HR, Bendall R, Ijaz S, Banks M. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis. 2008;8:698-709.
    • (2008) Lancet Infect Dis , vol.8 , pp. 698-709
    • Dalton, H.R.1    Bendall, R.2    Ijaz, S.3    Banks, M.4
  • 21
    • 85101728194 scopus 로고    scopus 로고
    • Hepatitis E
    • Comprehensive review of hepatitis E from a multinational group of opinion leaders. This is a "must read" for those interested in the field
    • •• Kamar N, Bendall R, Legrand-Abravanel F, Xia NS, Ijaz S, Izopet J, et al. Hepatitis E. Lancet. 2012;379:2477-88. Comprehensive review of hepatitis E from a multinational group of opinion leaders. This is a "must read" for those interested in the field.
    • (2012) Lancet , vol.379 , pp. 2477-2488
    • Kamar, N.1    Bendall, R.2    Legrand-Abravanel, F.3    Xia, N.S.4    Ijaz, S.5    Izopet, J.6
  • 22
    • 77951015275 scopus 로고    scopus 로고
    • A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries
    • Bendall R, Ellis V, Ijaz S, Ali R, Dalton H. A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries. J Med Virol. 2010;82:799-805.
    • (2010) J Med Virol , vol.82 , pp. 799-805
    • Bendall, R.1    Ellis, V.2    Ijaz, S.3    Ali, R.4    Dalton, H.5
  • 23
    • 84872032530 scopus 로고    scopus 로고
    • Test performance characteristics of Anti-HEV IgG assays strongly influence hepatitis E seroprevalence estimates
    • Wenzel JJ, Preiss J, Schemmerer M, Huber B, Jilg W. Test performance characteristics of Anti-HEV IgG assays strongly influence hepatitis E seroprevalence estimates. J Infect Dis. 2013;207:497-500.
    • (2013) J Infect Dis , vol.207 , pp. 497-500
    • Wenzel, J.J.1    Preiss, J.2    Schemmerer, M.3    Huber, B.4    Jilg, W.5
  • 24
    • 34250327144 scopus 로고    scopus 로고
    • Use of serological assays for diagnosis of hepatitis E virus genotype 1 and 3 infections in a setting of low endemicity
    • Herremans M, Bakker J, Duizer E, Vennema H, Koopmans MP. Use of serological assays for diagnosis of hepatitis E virus genotype 1 and 3 infections in a setting of low endemicity. Clin Vaccine Immunol. 2007;14:562-8.
    • (2007) Clin Vaccine Immunol , vol.14 , pp. 562-568
    • Herremans, M.1    Bakker, J.2    Duizer, E.3    Vennema, H.4    Koopmans, M.P.5
  • 27
    • 77954698248 scopus 로고    scopus 로고
    • Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: Pangenotypic evaluation of performances
    • Drobeniuc J, Meng J, Reuter G, Greene-Montfort T, Khudyakova N, Dimitrova Z, et al. Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performances. Clin Infect Dis. 2010;51:e24-7.
    • (2010) Clin Infect Dis , vol.51
    • Drobeniuc, J.1    Meng, J.2    Reuter, G.3    Greene-Montfort, T.4    Khudyakova, N.5    Dimitrova, Z.6
  • 28
    • 84877154849 scopus 로고    scopus 로고
    • An analysis of the benefit of using HEV genotype 3 antigens in detecting anti-HEV IgG in a European population
    • Schnegg A, Burgisser P, Andre C, Kenfak-Foguena A, Canellini G, Moradpour D, et al. An analysis of the benefit of using HEV genotype 3 antigens in detecting anti-HEV IgG in a European population. PLoS One. 2013;8:e62980.
    • (2013) PLoS One , vol.8
    • Schnegg, A.1    Burgisser, P.2    Andre, C.3    Kenfak-Foguena, A.4    Canellini, G.5    Moradpour, D.6
  • 30
    • 79953882444 scopus 로고    scopus 로고
    • Standardization of hepatitis E virus (HEV) nucleic acid amplification technique-based assays: An initial study to evaluate a panel of HEV strains and investigate laboratory performance
    • Baylis SA, Hanschmann KM, Blumel J, Nubling CM. Standardization of hepatitis E virus (HEV) nucleic acid amplification technique-based assays: an initial study to evaluate a panel of HEV strains and investigate laboratory performance. J Clin Microbiol. 2011;49:1234-9.
    • (2011) J Clin Microbiol , vol.49 , pp. 1234-1239
    • Baylis, S.A.1    Hanschmann, K.M.2    Blumel, J.3    Nubling, C.M.4
  • 31
    • 84876778342 scopus 로고    scopus 로고
    • World health organization international standard to harmonize assays for detection of hepatitis e virus RNA
    • Previous studies have shown very little interlaboratory concordance for HEV quantitative PCR. This paper defines WHO standards to harmonise HEV PCR assays and is a key paper in terms of laboratory diagnosis
    • •• Baylis SA, Blumel J, Mizusawa S, Matsubayashi K, Sakata H, Okada Y, et al. World health organization international standard to harmonize assays for detection of hepatitis e virus RNA. Emerg Infect Dis. 2013;19:729-35. Previous studies have shown very little interlaboratory concordance for HEV quantitative PCR. This paper defines WHO standards to harmonise HEV PCR assays and is a key paper in terms of laboratory diagnosis.
    • (2013) Emerg Infect Dis , vol.19 , pp. 729-735
    • Baylis, S.A.1    Blumel, J.2    Mizusawa, S.3    Matsubayashi, K.4    Sakata, H.5    Okada, Y.6
  • 32
    • 84878477273 scopus 로고    scopus 로고
    • Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections
    • Abravanel F, Chapuy-Regaud S, Lhomme S, Dubois M, Peron JM, Alric L, et al. Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections. J Clin Microbiol. 2013;51:1913-6.
    • (2013) J Clin Microbiol , vol.51 , pp. 1913-1916
    • Abravanel, F.1    Chapuy-Regaud, S.2    Lhomme, S.3    Dubois, M.4    Peron, J.M.5    Alric, L.6
  • 34
    • 84876007420 scopus 로고    scopus 로고
    • Hepatitis E: Clinical presentation in disease-endemic areas and diagnosis
    • Aggarwal R. Hepatitis E: clinical presentation in disease-endemic areas and diagnosis. Semin Liver Dis. 2013;33:30-40.
    • (2013) Semin Liver Dis , vol.33 , pp. 30-40
    • Aggarwal, R.1
  • 35
    • 33745348670 scopus 로고    scopus 로고
    • Hepatitis E virus genotyping based on full-length genome and partial genomic regions
    • DOI 10.1016/j.virusres.2006.01.013, PII S0168170206000323
    • Zhai L, Dai X, Meng J. Hepatitis E virus genotyping based on full-length genome and partial genomic regions. Virus Res. 2006;120:57-69. (Pubitemid 43947301)
    • (2006) Virus Research , vol.120 , Issue.1-2 , pp. 57-69
    • Zhai, L.1    Dai, X.2    Meng, J.3
  • 36
    • 31144477556 scopus 로고    scopus 로고
    • Phylogenetic analysis of global hepatitis E virus sequences: Genetic diversity, subtypes and zoonosis
    • DOI 10.1002/rmv.482
    • Lu L, Li C, Hagedorn CH. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol. 2006;16:5-36. (Pubitemid 43133591)
    • (2006) Reviews in Medical Virology , vol.16 , Issue.1 , pp. 5-36
    • Lu, L.1    Li, C.2    Hagedorn, C.H.3
  • 37
    • 84878668305 scopus 로고    scopus 로고
    • Genetic variability of HEV isolates: Inconsistencies of current classification
    • Oliveira-Filho EF, Konig M, Thiel HJ. Genetic variability of HEV isolates: inconsistencies of current classification. Vet Microbiol. 2013;165:148-54.
    • (2013) Vet Microbiol , vol.165 , pp. 148-154
    • Oliveira-Filho, E.F.1    Konig, M.2    Thiel, H.J.3
  • 38
    • 79953080091 scopus 로고    scopus 로고
    • Analysing complete genome sequence of swine hepatitis E virus (HEV), strain CHN-XJ-SW13 isolated from Xinjiang, China: Putative host range, and disease severity determinants in HEV
    • Fu H, Wang L, Zhu Y, Geng J, Li L, Wang X, et al. Analysing complete genome sequence of swine hepatitis E virus (HEV), strain CHN-XJ-SW13 isolated from Xinjiang, China: putative host range, and disease severity determinants in HEV. Infect Gen Evol J Mol Epidemiol Evol Genetics Infect Dis. 2011;11:618-23.
    • (2011) Infect Gen Evol J Mol Epidemiol Evol Genetics Infect Dis , vol.11 , pp. 618-623
    • Fu, H.1    Wang, L.2    Zhu, Y.3    Geng, J.4    Li, L.5    Wang, X.6
  • 39
    • 79956318858 scopus 로고    scopus 로고
    • A novel member of the family Hepeviridae from cutthroat trout (Oncorhynchus clarkii)
    • Batts W, Yun S, Hedrick R, Winton J. A novel member of the family Hepeviridae from cutthroat trout (Oncorhynchus clarkii). Virus Res. 2011;158:116-23.
    • (2011) Virus Res , vol.158 , pp. 116-123
    • Batts, W.1    Yun, S.2    Hedrick, R.3    Winton, J.4
  • 40
    • 84858975702 scopus 로고    scopus 로고
    • Transmission dynamics of hepatitis E virus in pigs: Estimation from field data and effect of vaccination
    • Backer JA, Berto A, McCreary C, Martelli F, van der Poel WH. Transmission dynamics of hepatitis E virus in pigs: estimation from field data and effect of vaccination. Epidemics. 2012;4:86-92.
    • (2012) Epidemics , vol.4 , pp. 86-92
    • Backer, J.A.1    Berto, A.2    McCreary, C.3    Martelli, F.4    Van Der Poel, W.H.5
  • 41
    • 84864476580 scopus 로고    scopus 로고
    • Hepatitis E virus strains in rabbits and evidence of a closely related strain in humans, France
    • HEVis demonstrated in farmed and wild rabbits in France and may have the potential to cause human disease
    • • Izopet J, Dubois M, Bertagnoli S, Lhomme S, Marchandeau S, Boucher S, et al. Hepatitis E virus strains in rabbits and evidence of a closely related strain in humans, France. Emerg Infect Dis. 2012;18:1274-81. HEVis demonstrated in farmed and wild rabbits in France and may have the potential to cause human disease.
    • (2012) Emerg Infect Dis , vol.18 , pp. 1274-1281
    • Izopet, J.1    Dubois, M.2    Bertagnoli, S.3    Lhomme, S.4    Marchandeau, S.5    Boucher, S.6
  • 43
    • 84864432820 scopus 로고    scopus 로고
    • Hepatitis E virus in pork food chain, United Kingdom, 2009-2010
    • A comprehensive study of HEVin pig products in the human food chain from slaughter to retail stores used by the public. HEV is demonstrated in every step of this chain and was found in 10% of pork sausages that were tested
    • •• Berto A, Martelli F, Grierson S, Banks M. Hepatitis E virus in pork food chain, United Kingdom, 2009-2010. Emerg Infect Dis. 2012;18:1358-60. A comprehensive study of HEVin pig products in the human food chain from slaughter to retail stores used by the public. HEV is demonstrated in every step of this chain and was found in 10% of pork sausages that were tested.
    • (2012) Emerg Infect Dis , vol.18 , pp. 1358-1360
    • Berto, A.1    Martelli, F.2    Grierson, S.3    Banks, M.4
  • 44
    • 84866161076 scopus 로고    scopus 로고
    • Thermal inactivation of infectious hepatitis E virus in experimentally contaminated food
    • Barnaud E, Rogee S, Garry P, Rose N, Pavio N. Thermal inactivation of infectious hepatitis E virus in experimentally contaminated food. Appl Environ Microbiol. 2012;78:5153-9.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 5153-5159
    • Barnaud, E.1    Rogee, S.2    Garry, P.3    Rose, N.4    Pavio, N.5
  • 45
    • 84930476411 scopus 로고    scopus 로고
    • Hepatitis E virus antibodies in blood donors, France
    • Using a highly sensitive assay, this paper shows that the HEV IgG seroprevalence in blood donors from the Southwest of France was 52%. This is much higher than previous estimates and suggests that HEV is hyperendemic in this region. These findings are congruent with the extrememy high incidence of hepatitis E that has been found in the Toulouse transplant population
    • •• Mansuy JM, Bendall R, Legrand-Abravanel F, Saune K, Miedouge M, Ellis V, et al. Hepatitis E virus antibodies in blood donors, France. Emerg Infect Dis. 2011;17:2309-12. Using a highly sensitive assay, this paper shows that the HEV IgG seroprevalence in blood donors from the Southwest of France was 52%. This is much higher than previous estimates and suggests that HEV is hyperendemic in this region. These findings are congruent with the extrememy high incidence of hepatitis E that has been found in the Toulouse transplant population.
    • (2011) Emerg Infect Dis , vol.17 , pp. 2309-2312
    • Mansuy, J.M.1    Bendall, R.2    Legrand-Abravanel, F.3    Saune, K.4    Miedouge, M.5    Ellis, V.6
  • 46
    • 84897449191 scopus 로고    scopus 로고
    • Hepatitis E virus in England and Wales: Indigenous infection is associated with the consumption of processed pork products
    • Said B, Ijaz S, Chand MA, Kafatos G, Tedder R, Morgan D. Hepatitis E virus in England and Wales: indigenous infection is associated with the consumption of processed pork products. Epidemiol Infect 2013:1-9.
    • (2013) Epidemiol Infect , pp. 1-9
    • Said, B.1    Ijaz, S.2    Chand, M.A.3    Kafatos, G.4    Tedder, R.5    Morgan, D.6
  • 47
    • 84870290939 scopus 로고    scopus 로고
    • Detection and molecular characterization of hepatitis E virus in clinical, environmental and putative animal sources
    • Ishida S, Yoshizumi S, Ikeda T, Miyoshi M, Goto A, Matsubayashi K, et al. Detection and molecular characterization of hepatitis E virus in clinical, environmental and putative animal sources. Arch Virol. 2012;157:2363-8.
    • (2012) Arch Virol , vol.157 , pp. 2363-2368
    • Ishida, S.1    Yoshizumi, S.2    Ikeda, T.3    Miyoshi, M.4    Goto, A.5    Matsubayashi, K.6
  • 48
    • 84870979905 scopus 로고    scopus 로고
    • Locally acquired hepatitis E. Geographical clustering and environmental factors: A nested case control study
    • Madden RG, Hunter JG, Stone AM, Thornton C, Barlow M, Lewis J, et al. Locally acquired hepatitis E. Geographical clustering and environmental factors: a nested case control study. J Hepatol. 2012;56:S64-5.
    • (2012) J Hepatol , vol.56
    • Madden, R.G.1    Hunter, J.G.2    Stone, A.M.3    Thornton, C.4    Barlow, M.5    Lewis, J.6
  • 50
    • 84881078589 scopus 로고    scopus 로고
    • Silent hepatitis E virus infection in Dutch blood donors, 2011 to 2012
    • HEV was denonstrated in 1 of 2,671 blood donors in the Netherlands by PCR
    • • Slot E, Hogema B, Riezebos-Brilman A, Kok T, Molier M, Zaaijer H. Silent hepatitis E virus infection in Dutch blood donors, 2011 to 2012. Euro Surveill 2013; 18. HEV was denonstrated in 1 of 2,671 blood donors in the Netherlands by PCR.
    • (2013) Euro Surveill , vol.18
    • Slot, E.1    Hogema, B.2    Riezebos-Brilman, A.3    Kok, T.4    Molier, M.5    Zaaijer, H.6
  • 51
    • 79952531910 scopus 로고    scopus 로고
    • Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors?
    • Beale MA, Tettmar K, Szypulska R, Tedder RS, Ijaz S. Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors? Vox Sang. 2011;100:340-2.
    • (2011) Vox Sang , vol.100 , pp. 340-342
    • Beale, M.A.1    Tettmar, K.2    Szypulska, R.3    Tedder, R.S.4    Ijaz, S.5
  • 52
    • 80052165161 scopus 로고    scopus 로고
    • The incidence of hepatitis E virus infection in the general population of the USA
    • Faramawi MF, Johnson E, Chen S, Pannala PR. The incidence of hepatitis E virus infection in the general population of the USA. Epidemiol Infect. 2011;139:1145-50.
    • (2011) Epidemiol Infect , vol.139 , pp. 1145-1150
    • Faramawi, M.F.1    Johnson, E.2    Chen, S.3    Pannala, P.R.4
  • 53
    • 84872941522 scopus 로고    scopus 로고
    • Laboratory-based surveillance for hepatitis E virus infection, United States, 2005-2012
    • This is the first structural and funtional study on hepatitis E virus using crystallography, giving insight on virus-host interactions
    • Drobeniuc J, Greene-Montfort T, Le NT, Mixson-Hayden TR, Ganova-Raeva L, Dong C, et al. Laboratory-based surveillance for hepatitis E virus infection, United States, 2005-2012. Emerg Infect Dis. 2013;19:218-22. This is the first structural and funtional study on hepatitis E virus using crystallography, giving insight on virus-host interactions.
    • (2013) Emerg Infect Dis , vol.19 , pp. 218-222
    • Drobeniuc, J.1    Greene-Montfort, T.2    Le, N.T.3    Mixson-Hayden, T.R.4    Ganova-Raeva, L.5    Dong, C.6
  • 56
    • 84861912781 scopus 로고    scopus 로고
    • First case report of an acute genotype 3 hepatitis E infected pregnant woman living in South-Eastern France
    • Anty R, Ollier L, Peron JM, Nicand E, Cannavo I, Bongain A, et al. First case report of an acute genotype 3 hepatitis E infected pregnant woman living in South-Eastern France. J Clin Virol. 2012;54:76-8.
    • (2012) J Clin Virol , vol.54 , pp. 76-78
    • Anty, R.1    Ollier, L.2    Peron, J.M.3    Nicand, E.4    Cannavo, I.5    Bongain, A.6
  • 59
    • 85027934906 scopus 로고    scopus 로고
    • Characteristics of Epstein-Barr virus hepatitis among patients with jaundice or acute hepatitis
    • HEV is the commonest cause of acute viral hepatitis in Cornwall, U.K.
    • • Vine LJ, Shepherd K, Hunter JG, Madden R, Thornton C, Ellis V, et al. Characteristics of Epstein-Barr virus hepatitis among patients with jaundice or acute hepatitis. Aliment Pharmacol Ther. 2012;36:16-21. HEV is the commonest cause of acute viral hepatitis in Cornwall, U.K.
    • (2012) Aliment Pharmacol Ther , vol.36 , pp. 16-21
    • Vine, L.J.1    Shepherd, K.2    Hunter, J.G.3    Madden, R.4    Thornton, C.5    Ellis, V.6
  • 60
    • 69949124139 scopus 로고    scopus 로고
    • Persistent carriage of hepatitis E virus in patients with HIVinfection
    • Dalton HR, Bendall RP, Keane FE, Tedder RS, Ijaz S. Persistent carriage of hepatitis E virus in patients with HIVinfection. N Engl J Med. 2009;361:1025-7.
    • (2009) N Engl J Med , vol.361 , pp. 1025-1027
    • Dalton, H.R.1    Bendall, R.P.2    Keane, F.E.3    Tedder, R.S.4    Ijaz, S.5
  • 61
    • 84886914384 scopus 로고    scopus 로고
    • Hepatitis E virus: An underestimated opportunistic pathogen in recipients of allogeneic hematopoietic stem cell transplantation
    • This is the first cohort study that describes chronic hepatitis E infections and reactivation of hematopoietic stem cell transplant recipients and the clinical presentation
    • • Versluis J, Pas SD, Agteresch HJ, de Man RA, Maaskant J, Schipper ME, et al. Hepatitis E virus: an underestimated opportunistic pathogen in recipients of allogeneic hematopoietic stem cell transplantation. Blood. 2013;122:1079-86. This is the first cohort study that describes chronic hepatitis E infections and reactivation of hematopoietic stem cell transplant recipients and the clinical presentation.
    • (2013) Blood , vol.122 , pp. 1079-1086
    • Versluis, J.1    Pas, S.D.2    Agteresch, H.J.3    De Man, R.A.4    Maaskant, J.5    Schipper, M.E.6
  • 65
    • 79955424791 scopus 로고    scopus 로고
    • Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants
    • This study provides the progression, outcomes, and factors associated with development of chronic HEVinfection in recipients of transplanted solid organs
    • • Kamar N, Garrouste C, Haagsma EB, Garrigue V, Pischke S, Chauvet C, et al. Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants. Gastroenterology. 2011;140:1481-9. This study provides the progression, outcomes, and factors associated with development of chronic HEVinfection in recipients of transplanted solid organs.
    • (2011) Gastroenterology , vol.140 , pp. 1481-1489
    • Kamar, N.1    Garrouste, C.2    Haagsma, E.B.3    Garrigue, V.4    Pischke, S.5    Chauvet, C.6
  • 69
    • 84860322521 scopus 로고    scopus 로고
    • Low risk of hepatitis E virus reactivation after haematopoietic stem cell transplantation
    • Abravanel F, Mansuy JM, Huynh A, Kamar N, Alric L, Peron JM, et al. Low risk of hepatitis E virus reactivation after haematopoietic stem cell transplantation. J Clin Virol. 2012;54:152-5.
    • (2012) J Clin Virol , vol.54 , pp. 152-155
    • Abravanel, F.1    Mansuy, J.M.2    Huynh, A.3    Kamar, N.4    Alric, L.5    Peron, J.M.6
  • 70
    • 84857058967 scopus 로고    scopus 로고
    • Chronic hepatitis E in hematopoietic stem cell transplant patients in a low-endemic country?
    • Koenecke C, Pischke S, Heim A, Raggub L, Bremer B, Raupach R, et al. Chronic hepatitis E in hematopoietic stem cell transplant patients in a low-endemic country? Transpl Infect Dis. 2012;14:103-6.
    • (2012) Transpl Infect Dis , vol.14 , pp. 103-106
    • Koenecke, C.1    Pischke, S.2    Heim, A.3    Raggub, L.4    Bremer, B.5    Raupach, R.6
  • 71
    • 66349093169 scopus 로고    scopus 로고
    • Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation
    • le Coutre P, Meisel H, Hofmann J, Rocken C, Vuong GL, Neuburger S, et al. Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation. Gut. 2009;58:699-702.
    • (2009) Gut , vol.58 , pp. 699-702
    • Le Coutre, P.1    Meisel, H.2    Hofmann, J.3    Rocken, C.4    Vuong, G.L.5    Neuburger, S.6
  • 72
    • 52749086450 scopus 로고    scopus 로고
    • Autochthonous hepatitis E in Southwest England: Natural history, complications and seasonal variation, and hepatitis E virus IgG seroprevalence in blood donors, the elderly and patients with chronic liver disease
    • Dalton HR, Stableforth W, Thurairajah P, Hazeldine S, Remnarace R, Usama W, et al. Autochthonous hepatitis E in Southwest England: natural history, complications and seasonal variation, and hepatitis E virus IgG seroprevalence in blood donors, the elderly and patients with chronic liver disease. Eur J Gastroenterol Hepatol. 2008;20:784-90.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , pp. 784-790
    • Dalton, H.R.1    Stableforth, W.2    Thurairajah, P.3    Hazeldine, S.4    Remnarace, R.5    Usama, W.6
  • 73
    • 0034332198 scopus 로고    scopus 로고
    • Low B-cell and monocyte counts on day 80 are associated with high infection rates between days 100 and 365 after allogeneic marrow transplantation
    • Storek J, Espino G, Dawson MA, Storer B, Flowers ME, Maloney DG. Low B-cell and monocyte counts on day 80 are associated with high infection rates between days 100 and 365 after allogeneic marrow transplantation. Blood. 2000;96:3290-3.
    • (2000) Blood , vol.96 , pp. 3290-3293
    • Storek, J.1    Espino, G.2    Dawson, M.A.3    Storer, B.4    Flowers, M.E.5    Maloney, D.G.6
  • 74
    • 82855172182 scopus 로고    scopus 로고
    • Insufficient recovery of thymopoiesis predicts for opportunistic infections in allogeneic hematopoietic stem cell transplant recipients
    • Wils EJ, van der Holt B, Broers AE, Posthumus-van Sluijs SJ, Gratama JW, Braakman E, et al. Insufficient recovery of thymopoiesis predicts for opportunistic infections in allogeneic hematopoietic stem cell transplant recipients. Haematologica. 2011;96:1846-54.
    • (2011) Haematologica , vol.96 , pp. 1846-1854
    • Wils, E.J.1    Van Der Holt, B.2    Broers, A.E.3    Posthumus-van Sluijs, S.J.4    Gratama, J.W.5    Braakman, E.6
  • 75
    • 10444231125 scopus 로고    scopus 로고
    • Thymopoiesis following allogeneic stem cell transplantation: New possibilities for improvement
    • DOI 10.1016/j.blre.2004.04.001, PII S0268960X04000190
    • Wils EJ, Cornelissen JJ. Thymopoiesis following allogeneic stem cell transplantation: new possibilities for improvement. Blood Rev. 2005;19:89-98. (Pubitemid 39643114)
    • (2005) Blood Reviews , vol.19 , Issue.2 , pp. 89-98
    • Wils, E.-J.1    Cornelissen, J.J.2
  • 76
    • 0031042008 scopus 로고    scopus 로고
    • Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts
    • DOI 10.1002/(SICI)1096-8652(199702)54:2<131::AID
    • Storek J, Gooley T, Witherspoon RP, Sullivan KM, Storb R. Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts. Am J Hematol. 1997;54:131-8. (Pubitemid 27079419)
    • (1997) American Journal of Hematology , vol.54 , Issue.2 , pp. 131-138
    • Storek, J.1    Gooley, T.2    Witherspoon, R.P.3    Sullivan, K.M.4    Storb, R.5
  • 77
    • 39549105800 scopus 로고    scopus 로고
    • Chronic hepatitis E with cirrhosis in a kidney-transplant recipient
    • DOI 10.1056/NEJMc0708687
    • Gerolami R, Moal V, Colson P. Chronic hepatitis E with cirrhosis in a kidney-transplant recipient. N Engl J Med. 2008;358:859-60. (Pubitemid 351281667)
    • (2008) New England Journal of Medicine , vol.358 , Issue.8 , pp. 859-860
    • Gerolami, R.1    Moal, V.2    Colson, P.3
  • 78
    • 79551633756 scopus 로고    scopus 로고
    • Hepatitis E virus and neurologic disorders
    • In a large Anglo-French cohort of acute and chronic hepatitis E patients, neurological complications were seen in 5%. In these cases, the LFTs were only mildly abnormal, and the neurological symptoms and signs completely dominated the clinical picture
    • •• Kamar N, Bendall RP, Peron JM, Cintas P, Prudhomme L, Mansuy JM, et al. Hepatitis E virus and neurologic disorders. Emerg Infect Dis. 2011;17:173-9. In a large Anglo-French cohort of acute and chronic hepatitis E patients, neurological complications were seen in 5%. In these cases, the LFTs were only mildly abnormal, and the neurological symptoms and signs completely dominated the clinical picture.
    • (2011) Emerg Infect Dis , vol.17 , pp. 173-179
    • Kamar, N.1    Bendall, R.P.2    Peron, J.M.3    Cintas, P.4    Prudhomme, L.5    Mansuy, J.M.6
  • 80
    • 84899051972 scopus 로고    scopus 로고
    • Guillain-Barré syndrome associated with preceding hepatitis E virus infection
    • In press, A case control study of 201 patients with Guillain-Barré syndrome from the Netherlands. Of patients with Guillain-Barré syndrome, 5% were shown to have hepatitis E at the onset of their neurological illness. The LFTs were mildly abnormal, neurological symptoms and signs dominated the clinical picture, and HEV-associated Guillain-Barré syndrome was clinically indistinguishable from cases not associated with HEV
    • •• van den Berg B, van der Eijk AA, Pas SD, Hunter JG, Madden RG, Thio-Gillen AP, et al. Guillain-Barré syndrome associated with preceding hepatitis E virus infection. In press, Neurology. A case control study of 201 patients with Guillain-Barré syndrome from the Netherlands. Of patients with Guillain-Barré syndrome, 5% were shown to have hepatitis E at the onset of their neurological illness. The LFTs were mildly abnormal, neurological symptoms and signs dominated the clinical picture, and HEV-associated Guillain-Barré syndrome was clinically indistinguishable from cases not associated with HEV.
    • Neurology
    • Van Den Berg, B.1    Van Der Eijk, A.A.2    Pas, S.D.3    Hunter, J.G.4    Madden, R.G.5    Thio-Gillen, A.P.6
  • 81
    • 84899116503 scopus 로고    scopus 로고
    • submitted. An Anglo-Dutch cohort study of 47 patients with neuralgic amyotrophy. Of patients with neuralgic amyotrophy, 10% were shown to have hepatitis E at the onset of their neurological illness. The LFTs were mildly abnormal; neurological symptoms and signs dominated the clinical picture
    • •• van Eijk JJ, Madden RG, van der Eijk AA, Hunter JG, Reimerink JHJ, Bendall RP, et al. Neuralgic amyotrophy and hepatitis E virus infection. submitted. An Anglo-Dutch cohort study of 47 patients with neuralgic amyotrophy. Of patients with neuralgic amyotrophy, 10% were shown to have hepatitis E at the onset of their neurological illness. The LFTs were mildly abnormal; neurological symptoms and signs dominated the clinical picture.
    • Neuralgic Amyotrophy and Hepatitis E Virus Infection
    • Van Eijk, J.J.1    Madden, R.G.2    Van Der Eijk, A.A.3    Hunter, J.G.4    Reimerink, J.H.J.5    Bendall, R.P.6
  • 83
  • 84
    • 52049107114 scopus 로고    scopus 로고
    • A case of transfusion-transmitted hepatitis E caused by blood from a donor infected with hepatitis E virus via zoonotic food-borne route
    • Matsubayashi K, Kang JH, Sakata H, Takahashi K, Shindo M, Kato M, et al. A case of transfusion-transmitted hepatitis E caused by blood from a donor infected with hepatitis E virus via zoonotic food-borne route. Transfusion. 2008;48:1368-75.
    • (2008) Transfusion , vol.48 , pp. 1368-1375
    • Matsubayashi, K.1    Kang, J.H.2    Sakata, H.3    Takahashi, K.4    Shindo, M.5    Kato, M.6
  • 87
    • 79956101582 scopus 로고    scopus 로고
    • Acute autochthonous hepatitis E in western patients with underlying chronic liver disease: A role for ribavirin?
    • This is the first structural and funtional study on hepatitis E virus using crystallography, giving insight on virus-host interactions
    • Peron JM, Dalton H, Izopet J, Kamar N. Acute autochthonous hepatitis E in western patients with underlying chronic liver disease: a role for ribavirin? J hepatol. 2011;54:1323-4. This is the first structural and funtional study on hepatitis E virus using crystallography, giving insight on virus-host interactions.
    • (2011) J Hepatol , vol.54 , pp. 1323-1324
    • Peron, J.M.1    Dalton, H.2    Izopet, J.3    Kamar, N.4
  • 88
  • 91
    • 84875974128 scopus 로고    scopus 로고
    • Hepatitis E virus infection in immunosuppressed patients: Natural history and therapy
    • Kamar N, Rostaing L, Izopet J. Hepatitis E virus infection in immunosuppressed patients: natural history and therapy. Semin Liver Dis. 2013;33:62-70.
    • (2013) Semin Liver Dis , vol.33 , pp. 62-70
    • Kamar, N.1    Rostaing, L.2    Izopet, J.3
  • 93
    • 76649114021 scopus 로고    scopus 로고
    • Influence of immunosuppressive therapy on the natural history of genotype 3 hepatitis-E virus infection after organ transplantation
    • Kamar N, Abravanel F, Selves J, Garrouste C, Esposito L, Lavayssiere L, et al. Influence of immunosuppressive therapy on the natural history of genotype 3 hepatitis-E virus infection after organ transplantation. Transplantation. 2010;89:353-60.
    • (2010) Transplantation , vol.89 , pp. 353-360
    • Kamar, N.1    Abravanel, F.2    Selves, J.3    Garrouste, C.4    Esposito, L.5    Lavayssiere, L.6
  • 95
    • 78049469347 scopus 로고    scopus 로고
    • Ribavirin therapy inhibits viral replication on patients with chronic hepatitis e virus infection
    • This is the first study to describe ribavirine as an option for hepatitis E virus infection treatment
    • • Kamar N, Rostaing L, Abravanel F, Garrouste C, Lhomme S, Esposito L, et al. Ribavirin therapy inhibits viral replication on patients with chronic hepatitis e virus infection. Gastroenterology. 2010;139:1612-8. This is the first study to describe ribavirine as an option for hepatitis E virus infection treatment.
    • (2010) Gastroenterology , vol.139 , pp. 1612-1618
    • Kamar, N.1    Rostaing, L.2    Abravanel, F.3    Garrouste, C.4    Lhomme, S.5    Esposito, L.6
  • 97
    • 37549061837 scopus 로고    scopus 로고
    • High prevalence of anti-hepatitis E virus antibodies in blood donors from South West France
    • Mansuy JM, Legrand-Abravanel F, Calot JP, Peron JM, Alric L, Agudo S, et al. High prevalence of anti-hepatitis E virus antibodies in blood donors from South West France. J Med Virol. 2008;80:289-93.
    • (2008) J Med Virol , vol.80 , pp. 289-293
    • Mansuy, J.M.1    Legrand-Abravanel, F.2    Calot, J.P.3    Peron, J.M.4    Alric, L.5    Agudo, S.6
  • 99
    • 84860289619 scopus 로고    scopus 로고
    • Occurrence of hepatitis E virus RNA in plasma donations from Sweden, Germany and the United States
    • This is a very nice overview of the incidence of hepatitis E virus in blood donors in industrialized countries
    • • Baylis SA, Gartner T, Nick S, Ovemyr J, Blumel J. Occurrence of hepatitis E virus RNA in plasma donations from Sweden, Germany and the United States. Vox Sang. 2012;103:89-90. This is a very nice overview of the incidence of hepatitis E virus in blood donors in industrialized countries.
    • (2012) Vox Sang , vol.103 , pp. 89-90
    • Baylis, S.A.1    Gartner, T.2    Nick, S.3    Ovemyr, J.4    Blumel, J.5
  • 101
    • 84858171673 scopus 로고    scopus 로고
    • Detection of hepatitis E virus RNA in plasma mini-pools from blood donors in England
    • Ijaz S, Szypulska R, Tettmar KI, Kitchen A, Tedder RS. Detection of hepatitis E virus RNA in plasma mini-pools from blood donors in England. Vox Sang. 2012;102:272.
    • (2012) Vox Sang , vol.102 , pp. 272
    • Ijaz, S.1    Szypulska, R.2    Tettmar, K.I.3    Kitchen, A.4    Tedder, R.S.5
  • 102
    • 0029762301 scopus 로고    scopus 로고
    • A community prevalence study of antibodies to hepatitis A and E in inner-city London
    • DOI 10.1002/(SICI)1096-9071(199607)49:3<230::AID
    • Bernal W, Smith HM, Williams R. A community prevalence study of antibodies to hepatitis A and E in inner-city London. J Med Virol. 1996;49:230-4. (Pubitemid 26291389)
    • (1996) Journal of Medical Virology , vol.49 , Issue.3 , pp. 230-234
    • Bernal, W.1    Smith, H.M.2    Williams, R.3
  • 103
    • 31144435180 scopus 로고    scopus 로고
    • Unexpected high prevalence of IgG-antibodies to hepatitis E virus in Swedish pig farmers and controls
    • DOI 10.1080/00365540500321470, PII P163434808205437
    • Olsen B, Axelsson-Olsson D, Thelin A, Weiland O. Unexpected high prevalence of IgG-antibodies to hepatitis E virus in Swedish pig farmers and controls. Scand J Infect Dis. 2006;38:55-8. (Pubitemid 43123844)
    • (2006) Scandinavian Journal of Infectious Diseases , vol.38 , Issue.1 , pp. 55-58
    • Olsen, B.1    Axelsson-Olsson, D.2    Thelin, A.3    Weiland, O.4
  • 105
    • 84891703675 scopus 로고    scopus 로고
    • An assessment of hepatitis E virus (HEV) in US blood donors and recipients: No detectable HEV RNA in 1939 donors tested and no evidence for HEV transmission to 362 prospectively followed recipients
    • Xu C, Wang RY, Schechterly CA, Ge S, Shih JW, Xia NS, et al. An assessment of hepatitis E virus (HEV) in US blood donors and recipients: no detectable HEV RNA in 1939 donors tested and no evidence for HEV transmission to 362 prospectively followed recipients. Transfusion 2013.
    • (2013) Transfusion
    • Xu, C.1    Wang, R.Y.2    Schechterly, C.A.3    Ge, S.4    Shih, J.W.5    Xia, N.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.