-
1
-
-
79952232216
-
Global cancer statistics
-
21296855 10.3322/caac.20107
-
A. Jemal, F. Bray, M.M. Center, J. Ferlay, E. Ward, D. Forman, Global cancer statistics. CA Cancer J. Clin. 61, 69-90 (2011)
-
(2011)
CA Cancer J. Clin.
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
1:CAS:528:DC%2BC3MXjtVWrs7k%3D 21090969 10.1146/annurev-pathol-011110- 130235
-
E.R. Fearon, Molecular genetics of colorectal cancer. Annu. Rev. Pathol. 6, 479-507 (2011)
-
(2011)
Annu. Rev. Pathol.
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
3
-
-
0027405720
-
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
-
DOI 10.1016/0092-8674(93)90406-G
-
J.A. Trofatter, M.M. MacCollin, J.L. Rutter, J.R. Murrell, M.P. Duyao, D.M. Parry, R. Eldridge, N. Kley, A.G. Menon, K. Pulaski, A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 72, 791-800 (1993) (Pubitemid 23093886)
-
(1993)
Cell
, vol.72
, Issue.5
, pp. 791-800
-
-
Trofatter, J.A.1
MacCollin, M.M.2
Rutter, J.L.3
Murrell, J.R.4
Duyao, M.P.5
Parry, D.M.6
Eldridge, R.7
Kley, N.8
Menon, A.G.9
Pulaski, K.10
Haase, V.H.11
Ambrose, C.M.12
Munroe, D.13
Bove, C.14
Haines, J.L.15
Martuza, R.L.16
MacDonald, M.E.17
Seizinger, B.R.18
Short, M.P.19
-
4
-
-
34247609343
-
Shedding light on Merlin's wizardry
-
DOI 10.1016/j.tcb.2007.03.006, PII S0962892407000839
-
T. Okada, L. You, F.G. Giancotti, Shedding light on Merlin's wizardry. Trends Cell Biol. 17, 222-229 (2007) (Pubitemid 46679247)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.5
, pp. 222-229
-
-
Okada, T.1
You, L.2
Giancotti, F.G.3
-
5
-
-
67649878206
-
Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling signaling in a mouse model of renal carcinoma
-
1:CAS:528:DC%2BD1MXotFGjsrc%3D 19487675 10.1073/pnas.0902031106
-
Z.S. Morris, A.I. McClatchey, Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling signaling in a mouse model of renal carcinoma. Proc. Natl. Acad. Sci. 106, 9767-9772 (2009)
-
(2009)
Proc. Natl. Acad. Sci.
, vol.106
, pp. 9767-9772
-
-
Morris, Z.S.1
McClatchey, A.I.2
-
6
-
-
79955040874
-
The FERM family proteins in cancer invasion and metastasis
-
1:CAS:528:DC%2BC3MXisVylsb0%3D 10.2741/3803
-
H. Yu, Y. Zhang, L. Ye, W.G. Jiang, The FERM family proteins in cancer invasion and metastasis. Front. Biosci. 16, 1536-1550 (2011)
-
(2011)
Front. Biosci.
, vol.16
, pp. 1536-1550
-
-
Yu, H.1
Zhang, Y.2
Ye, L.3
Jiang, W.G.4
-
7
-
-
78649631289
-
Merlin, a magic linker between the extracellular cues and intracelular signaling pathways that regulate cell motility, proliferation and survival
-
1:CAS:528:DC%2BC3cXhtFersb7N 20491622 10.2174/138920310791824011 2946555
-
I. Stamenkovic, Q. Yu, Merlin, a magic linker between the extracellular cues and intracelular signaling pathways that regulate cell motility, proliferation and survival. Curr. Protein Pept. Sci. 11, 471-484 (2010)
-
(2010)
Curr. Protein Pept. Sci.
, vol.11
, pp. 471-484
-
-
Stamenkovic, I.1
Yu, Q.2
-
8
-
-
0028201083
-
Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types
-
DOI 10.1038/ng0294-185
-
A.B. Bianchi, T. Hara, V. Ramesh, J. Gao, A.J. Klein-Szanto, F. Morin, A.G. Menon, J.A. Trofatter, J.F. Gusella, B.R. Seizinger, N. Kley, Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types. Nat. Genet. 6, 185-192 (1994) (Pubitemid 24188601)
-
(1994)
Nature Genetics
, vol.6
, Issue.2
, pp. 185-192
-
-
Bianchi, A.B.1
Hara, T.2
Ramesh, V.3
Gao, J.4
Klein-Szanto, A.J.P.5
Morin, F.6
Menon, A.G.7
Trofatter, J.A.8
Gusella, J.F.9
Seizinger, B.R.10
Kley, N.11
-
9
-
-
0030775695
-
Interdomain binding mediates tumor growth suppression by the NF2 gene product
-
L. Sherman, H.M. Xu, R.T. Geist, S. Saporito-Irwin, N. Howells, H. Ponta, P. Herrlich, D.H. Gutmann, Interdomain binding mediates tumor growth suppression by the NF2 gene product. Oncogene 15, 2505-2509 (1997) (Pubitemid 27503537)
-
(1997)
Oncogene
, vol.15
, Issue.20
, pp. 2505-2509
-
-
Sherman, L.1
Xu, H.-M.2
Geist, R.T.3
Saporito-Irwin, S.4
Howells, N.5
Ponta, H.6
Herrlich, P.7
Gutmann, D.H.8
-
10
-
-
0033485979
-
Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations
-
1:CAS:528:DyaK1MXnslyksLk%3D 10561699 10.1002/(SICI)1097-4547(19991201) 58:5<706: AID-JNR12>3.0.CO;2-Z
-
D.H. Gutmann, C.A. Haipek, L.K. Hoang, Neurofibromatosis 2 tumor suppressor protein, merlin, forms two functionally important intramolecular associations. J. Neurosci. Res. 58, 706-716 (1999)
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 706-716
-
-
Gutmann, D.H.1
Haipek, C.A.2
Hoang, L.K.3
-
11
-
-
0037059807
-
P21-activated kinase links Rac/Cdc42 signaling to merlin
-
DOI 10.1074/jbc.C100553200
-
G.H. Xiao, A. Beeser, J. Chernoff, J.R. Testa, p21-activated kinase links Rac/Cdc42 signaling to merlin. J. Biol. Chem. 277, 883-886 (2002) (Pubitemid 34968830)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.2
, pp. 883-886
-
-
Xiao, G.-H.1
Beeser, A.2
Chernoff, J.3
Testa, J.R.4
-
12
-
-
2442629479
-
Cyclic AMP-dependent Protein Kinase Phosphorylates Merlin at Serine 518 Independently of p21-activated Kinase and Promotes Merlin-Ezrin Heterodimerization
-
DOI 10.1074/jbc.M313916200
-
K. Alfthan, L. Heiska, M. Gronholm, G.H. Renkema, O. Carpen, Cyclic AMP dependent protein kinase phosphorylates Merlin at serine 518 independently of p21-activated kinase and promotes Merlin-Ezrin heterodimerization. J. Biol. Chem. 279, 1859-1866 (2004) (Pubitemid 38623276)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.18
, pp. 18559-18566
-
-
Alfthan, K.1
Heiska, L.2
Gronholm, M.3
Renkema, G.H.4
Carpen, O.5
-
13
-
-
0242583906
-
Merlin and ERM proteins: Unappreciated roles in cancer development?
-
14668818 10.1038/nrc1213
-
A.I. McClatchey, Merlin and ERM proteins: unappreciated roles in cancer development? Nat. Rev. Cancer 3, 877-884 (2003)
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 877-884
-
-
McClatchey, A.I.1
-
14
-
-
0032571272
-
Regulation of the neurofibromatosis type 2 tumor suppressor protein, Merlin, by adhesion and growth arrest stimuli
-
DOI 10.1074/jbc.273.13.7757
-
R.J. Shaw, A.I. McClatchey, T. Jacks, Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli. J. Biol. Chem. 273, 7757-7764 (1998) (Pubitemid 28152808)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.13
, pp. 7757-7764
-
-
Shaw, R.J.1
McClatchey, A.I.2
Jacks, T.3
-
15
-
-
18044399847
-
The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling
-
DOI 10.1016/S1534-5807(01)00009-0, PII S1534580701000090
-
R.J. Shaw, J.G. Paez, M. Curto, A. Yaktine, W.M. Pruitt, I. Saotome, J. O'Bryan, V. Gupta, N. Ratner, C.J. Der, T. Jacks, A.I. McClatchey, The NF2 tumor suppressor, merlin, functions in Rac-dependent signaling. Dev. Cell 1, 63-72 (2001) (Pubitemid 33586069)
-
(2001)
Developmental Cell
, vol.1
, Issue.1
, pp. 63-72
-
-
Shaw, R.J.1
Paez, J.G.2
Curto, M.3
Yaktine, A.4
Pruitt, W.M.5
Saotome, I.6
O'Bryan, J.P.7
Gupta, V.8
Ratner, N.9
Der, C.J.10
Jacks, T.11
McClatchey, A.I.12
-
16
-
-
27544514090
-
Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
-
DOI 10.1083/jcb.200503165
-
T. Okada, M. Lopez-Lago, F.G. Giancotti, Merlin/NF2 mediates contact inhibition of growh by suppressing recruitment of Rac to the plasma membrane. J. Cell Biol. 171, 361-371 (2005) (Pubitemid 41540027)
-
(2005)
Journal of Cell Biology
, vol.171
, Issue.2
, pp. 361-371
-
-
Okada, T.1
Lopez-Lago, M.2
Giancotti, F.G.3
-
17
-
-
60149106862
-
Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas
-
1:CAS:528:DC%2BD1cXhsVWgsr%2FI 19029950 10.1038/onc.2008.427
-
D. Lallemand, J. Manent, A. Couvelard, A. Watilliaux, M. Siena, F. Chareyre, A. Lampin, M. Niwa-Kawakita, M. Kalamarides, M. Giovannini, Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas. Oncogene 28, 854-865 (2009)
-
(2009)
Oncogene
, vol.28
, pp. 854-865
-
-
Lallemand, D.1
Manent, J.2
Couvelard, A.3
Watilliaux, A.4
Siena, M.5
Chareyre, F.6
Lampin, A.7
Niwa-Kawakita, M.8
Kalamarides, M.9
Giovannini, M.10
-
18
-
-
38549112079
-
Nf2/Merlin: A coordinator of receptor signalling and intercellular contact
-
DOI 10.1038/sj.bjc.6604002, PII 6604002
-
M. Curto, A.I. McClatchey, Nf2/Merlin: A coordinator of receptor signalling and intercellular contact. Br. J. Cancer 98, 256-262 (2008) (Pubitemid 351161230)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.2
, pp. 256-262
-
-
Curto, M.1
McClatchey, A.I.2
-
19
-
-
34249913434
-
Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
-
DOI 10.1083/jcb.200703010
-
M. Curto, B.K. Cole, D. Lallemand, C.H. Liu, A.I. McClatchey, Contact-dependent inhibition of EGFR signaling by Nf2/Merlin. J. Cell Biol. 177, 893-903 (2007) (Pubitemid 46873094)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.5
, pp. 893-903
-
-
Curto, M.1
Cole, B.K.2
Lallemand, D.3
Liu, C.-H.4
McClatchey, A.I.5
-
20
-
-
65149104670
-
Merlin and the ERM proteins: Regulators of receptor distribution and signaling at the cell cortex
-
19345106 10.1016/j.tcb.2009.02.006 2796113
-
A.I. McClatchey, R.G. Fehon, Merlin and the ERM proteins: regulators of receptor distribution and signaling at the cell cortex. Trends Cell Biol. 19, 198-206 (2009)
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 198-206
-
-
McClatchey, A.I.1
Fehon, R.G.2
-
21
-
-
77951877496
-
NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation
-
1:CAS:528:DC%2BC3cXhvFGms74%3D 20154721 10.1038/onc.2010.20 2861729
-
E.E. Bosco, Y. Nakai, E.F. Hennigan, N. Ratner, Y. Zheng, NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation. Oncogene 29, 2540-2549 (2010)
-
(2010)
Oncogene
, vol.29
, pp. 2540-2549
-
-
Bosco, E.E.1
Nakai, Y.2
Hennigan, E.F.3
Ratner, N.4
Zheng, Y.5
-
22
-
-
84855434528
-
Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-Catenin signaling linked to the PDGFR/Src and Rac/PAK pathways
-
1:CAS:528:DC%2BC38XhsVSgtb8%3D 22247700 3257450
-
L. Zhou, E. Ercolano, S. Ammoun, M.C. Schmid, M.A. Barczyk, C.O. Hanemann, Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-Catenin signaling linked to the PDGFR/Src and Rac/PAK pathways. Neoplasia 13, 1101-1112 (2011)
-
(2011)
Neoplasia
, vol.13
, pp. 1101-1112
-
-
Zhou, L.1
Ercolano, E.2
Ammoun, S.3
Schmid, M.C.4
Barczyk, M.A.5
Hanemann, C.O.6
-
23
-
-
23444454151
-
Human tumour bank in Croatia: A possible model for a small bank as part of the future European tumour bank network [4]
-
DOI 10.1016/0959-8049(94)90277-1
-
R. Spaventi, L. Pecur, K. Pavelic, Z.P. Pavelic, S. Spaventi, P.J. Stambrook, Human tumour bank in Croatia: a possible model for a small bank as a part of future European tumour bank network. Eur. J. Cancer 30A, 419 (1994) (Pubitemid 24152494)
-
(1994)
European Journal of Cancer Part A: General Topics
, vol.30
, Issue.3
, pp. 419
-
-
Spaventi, R.1
Pecur, L.2
Pavelic, K.3
Pavelic, Z.P.4
Spaventi, S.5
Stambrook, P.J.6
-
24
-
-
0033055333
-
Characterisation of 16 polymorphic markers in the NF2 gene: Application to hemizygosity detection
-
DOI 10.1002/(SICI)1098-1004(1999)13:4 <290::AID-HUMU5>3.0.CO;2-C
-
P. Legoix, M.-F. Legrand, E. Ollagnon, G. Lenoir, G. Thomas, J. Zucman-Rossi, Characterisation of 16 polymorphic markers in the NF2 gene: application to hemizygosity detection. Hum. Mutat. 13, 290-293 (1999) (Pubitemid 29307073)
-
(1999)
Human Mutation
, vol.13
, Issue.4
, pp. 290-293
-
-
Legoix, P.1
Legrand, M.-F.2
Ollagnon, E.3
Lenoir, G.4
Thomas, G.5
Zucman-Rossi, J.6
-
25
-
-
22644446003
-
NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer
-
DOI 10.1136/gut.2004.053348
-
T. Cacev, S. Radosevic, R. Spaventi, K. Pavelic, S. Kapitanovic, NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer. Gut 54, 1129-1135 (2005) (Pubitemid 41025908)
-
(2005)
Gut
, vol.54
, Issue.8
, pp. 1129-1135
-
-
Cacev, T.1
Radosevic, S.2
Spaventi, R.3
Pavelic, K.4
Kapitanovic, S.5
-
26
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
1:CAS:528:DC%2BC3MXjsFeqtrk%3D 21376230 10.1016/j.cell.2011.02.013
-
D. Hanahan, R.A. Weinberg, Hallmarks of cancer: The next generation. Cell 144, 646-674 (2011)
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
27
-
-
0032522603
-
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors
-
A.I. McClatchey, I. Saotome, K. Mercer, D. Crowley, J.F. Gusella, R.T. Bronson, T. Jacks, Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors. Genes Dev. 12, 1121-1133 (1998) (Pubitemid 28194048)
-
(1998)
Genes and Development
, vol.12
, Issue.8
, pp. 1121-1133
-
-
McClatchey, A.I.1
Saotome, I.2
Mercer, K.3
Crowley, D.4
Gusella, J.F.5
Bronson, R.T.6
Jacks, T.7
-
28
-
-
48649109725
-
Merlin is a potent inhibitor of glioma growth
-
1:CAS:528:DC%2BD1cXovVCns7g%3D 18632626 10.1158/0008-5472.CAN-08-0190 2778036
-
Y.K. Lau, L.B. Murray, S.S. Houshmandi, Y. Xu, D.H. Gutmann, Q. Yu, Merlin is a potent inhibitor of glioma growth. Cancer Res. 68, 5733-5742 (2008)
-
(2008)
Cancer Res.
, vol.68
, pp. 5733-5742
-
-
Lau, Y.K.1
Murray, L.B.2
Houshmandi, S.S.3
Xu, Y.4
Gutmann, D.H.5
Yu, Q.6
-
29
-
-
0027245423
-
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2
-
DOI 10.1038/363515a0
-
G.A. Rouleau, P. Merel, M. Lutchman, M. Sanson, J. Zucman, C. Marineau, K. Hoang-Xuan, S. Demczuk, C. Desmaze, B. Plougastel, Alteration in a new gene encoding a putative membrane-organizing protein causes neurofibromatosis type 2. Nature 363, 515-521 (1993) (Pubitemid 23186636)
-
(1993)
Nature
, vol.363
, Issue.6429
, pp. 515-521
-
-
Rouleau, G.A.1
Merel, P.2
Lutchman, M.3
Sanson, M.4
Zucman, J.5
Marineau, C.6
Hoang- Xuan, K.7
Demczuk, S.8
Desmaze, C.9
Plougastel, B.10
Pulst, S.M.11
Lenoir, G.12
Bijlsma, E.13
Fashold, R.14
Dumanski, J.15
De Jong, P.16
Parry, D.17
Eldrige, R.18
Aurias, A.19
-
30
-
-
0028785794
-
Neurofibromatosis 2 gene in human colorectal cancer
-
1:CAS:528:DyaK28XhtFSmur0%3D 7497438 10.1016/0165-4608(95)00059-3
-
A.K. Rustgi, L. Xu, D. Pinney, C. Sterner, R. Beauchamp, S. Schmidt, J.F. Gusella, V. Ramesh, Neurofibromatosis 2 gene in human colorectal cancer. Cancer Genet. Cytogenet. 84, 24-26 (1995)
-
(1995)
Cancer Genet. Cytogenet.
, vol.84
, pp. 24-26
-
-
Rustgi, A.K.1
Xu, L.2
Pinney, D.3
Sterner, C.4
Beauchamp, R.5
Schmidt, S.6
Gusella, J.F.7
Ramesh, V.8
-
31
-
-
0036678430
-
Loss of heterozygosity on long arm of chromosome 22 in sporadic colorectal carcinoma
-
C.Z. Zhou, Z.H. Peng, F. Zhang, G.Q. Qiu, L. He, Loss of heterozygosity on long arm of chromosome 22 in sporadic colorectal carcinoma. World J. Gastroenterol. 8, 668-673 (2000)
-
(2000)
World J. Gastroenterol.
, vol.8
, pp. 668-673
-
-
Zhou, C.Z.1
Peng, Z.H.2
Zhang, F.3
Qiu, G.Q.4
He, L.5
-
32
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan, R.A. Weinberg, The hallmarks of cancer. Cell 100, 57-70 (2000) (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
33
-
-
79952081852
-
Alternative pre-mRNA splicing in digestive tract malignancy
-
1:CAS:528:DC%2BC3MXitFSmtLs%3D 21134075 10.1111/j.1349-7006.2010.01797.x
-
K. Miura, W. Fujibuchi, I. Sasaki, Alternative pre-mRNA splicing in digestive tract malignancy. Cancer Sci. 102, 309-316 (2011)
-
(2011)
Cancer Sci.
, vol.102
, pp. 309-316
-
-
Miura, K.1
Fujibuchi, W.2
Sasaki, I.3
-
34
-
-
0028274156
-
Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers
-
H. Arakawa, N. Hayashi, H. Nagase, M. Ogawa, Y. Nakamura, Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers. Hum. Mol. Genet. 3, 565-568 (1994) (Pubitemid 24122167)
-
(1994)
Human Molecular Genetics
, vol.3
, Issue.4
, pp. 565-568
-
-
Arakawa, H.1
Hayashi, N.2
Nagase, H.3
Ogawa, M.4
Nakamura, Y.5
-
35
-
-
0034060838
-
A unique method for mutation analysis of tumor suppressor genes in colorectal carcinomas using a crypt isolation technique
-
T. Sugai, W. Habano, S. Nakamura, N. Uesugi, S. Sasou, C. Itoh, A unique method for mutation analysis of tumor suppressor genes in colorectal carcinomas using a crypt isolation technique. Arch. Pathol. Lab. Med. 124, 382-386 (2000) (Pubitemid 30152139)
-
(2000)
Archives of Pathology and Laboratory Medicine
, vol.124
, Issue.3
, pp. 382-386
-
-
Sugai, T.1
Habano, W.2
Nakamura, S.-I.3
Uesugi, N.4
Sasou, S.5
Itoh, C.6
-
36
-
-
84863243795
-
Mutational analysis of tumour suppressor gene NF2 in common solid cancers and acute leukaemias
-
1:CAS:528:DC%2BC38Xjs12isLw%3D 22081132 10.1097/PAT.0b013e32834c3599
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N.J. Yoo, S.W. Park, S.H. Lee, Mutational analysis of tumour suppressor gene NF2 in common solid cancers and acute leukaemias. Pathology 44, 29-32 (2012)
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(2012)
Pathology
, vol.44
, pp. 29-32
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Yoo, N.J.1
Park, S.W.2
Lee, S.H.3
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