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Volumn 44, Issue 2, 2014, Pages 491-504

Segregation of signaling proteins as prognostic predictors for local recurrence and distant metastasis in hepatocellular carcinoma

Author keywords

Extrahepatic metastasis; Hepatocellular carcinoma; Local recurrence; Signaling proteins; Survival

Indexed keywords

BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; COHORT STUDIES; FEMALE; HEP G2 CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 84894429094     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2198     Document Type: Article
Times cited : (5)

References (36)
  • 2
    • 33748114343 scopus 로고    scopus 로고
    • The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
    • DOI 10.1016/j.jhep.2006.05.013, PII S0168827806002972
    • Perz JF, Armstrong GL, Farrington LA, Hutin YJ and Bell BP: The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol 45: 529-538, 2006. (Pubitemid 44307383)
    • (2006) Journal of Hepatology , vol.45 , Issue.4 , pp. 529-538
    • Perz, J.F.1    Armstrong, G.L.2    Farrington, L.A.3    Hutin, Y.J.F.4    Bell, B.P.5
  • 3
    • 0026735233 scopus 로고
    • Hepatitis B virus, cigarette smoking and alcohol consumption in the development of hepatocellular carcinoma: A case-control study in Fukuoka, Japan
    • Tanaka K, Hirohata T, Takeshita S, Hirohata I, Koga S, Sugimachi K, Kanematsu T, Ohryohji F and Ishibashi H: Hepatitis B virus, cigarette smoking and alcohol consumption in the development of hepatocellular carcinoma: a case-control study in Fukuoka, Japan. Int J Cancer 51: 509-514, 1992.
    • (1992) Int J Cancer , vol.51 , pp. 509-514
    • Tanaka, K.1    Hirohata, T.2    Takeshita, S.3    Hirohata, I.4    Koga, S.5    Sugimachi, K.6    Kanematsu, T.7    Ohryohji, F.8    Ishibashi, H.9
  • 5
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in the United States
    • El-Serag HB: Hepatocellular carcinoma: recent trends in the United States. Gastroenterology 127: S27-S34, 2004.
    • (2004) Gastroenterology , vol.127
    • El-Serag, H.B.1
  • 6
    • 20344392430 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology, risk factors, and screening
    • Sherman M: Hepatocellular carcinoma: epidemiology, risk factors, and screening. Semin Liver Dis 25: 143-154, 2005.
    • (2005) Semin Liver Dis , vol.25 , pp. 143-154
    • Sherman, M.1
  • 7
    • 33747496317 scopus 로고    scopus 로고
    • Chronic hepatitis B in hepatocarcinogenesis
    • DOI 10.1136/pgmj.2006.047431
    • Park NH, Song IH and Chung YH: Chronic hepatitis B in hepatocarcinogenesis. Postgrad Med J 82: 507-515, 2006. (Pubitemid 44258625)
    • (2006) Postgraduate Medical Journal , vol.82 , Issue.970 , pp. 507-515
    • Park, N.H.1    Song, I.H.2    Chung, Y.-H.3
  • 8
    • 0034028927 scopus 로고    scopus 로고
    • Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma
    • Chau GY, Wu CW, Lui WY, Chang TJ, Kao HL, Wu LH, King KL, Loong CC, Hsia CY and Chi CW: Serum interleukin-10 but not interleukin-6 is related to clinical outcome in patients with resectable hepatocellular carcinoma. Ann Surg 231: 552-558, 2000.
    • (2000) Ann Surg , vol.231 , pp. 552-558
    • Chau, G.Y.1    Wu, C.W.2    Lui, W.Y.3    Chang, T.J.4    Kao, H.L.5    Wu, L.H.6    King, K.L.7    Loong, C.C.8    Hsia, C.Y.9    Chi, C.W.10
  • 9
    • 33747365877 scopus 로고    scopus 로고
    • Proline-directed protein kinase FA is a powerful and independent prognostic predictor for progression and patient survival of hepatocellular carcinoma
    • Hsu YC, Fu HH, Jeng YM, Lee PH and Yang SD: Proline-directed protein kinase FA is a powerful and independent prognostic predictor for progression and patient survival of hepatocellular carcinoma. J Clin Oncol 24: 3780-3788, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 3780-3788
    • Hsu, Y.C.1    Fu, H.H.2    Jeng, Y.M.3    Lee, P.H.4    Yang, S.D.5
  • 10
    • 0027240655 scopus 로고
    • The assessment of proliferating cell nuclear antigen immunohistochemical staining in small hepatocellular carcinoma and its relationship to histologic characteristics and prognosis
    • Kitamoto M, Nakanishi T, Kira S, Kawaguchi M, Nakashio R, Suemori S, Kajiyama G, Asahara T and Dohi K: The assessment of proliferating cell nuclear antigen immunohistochemical staining in small hepatocellular carcinoma and its relationship to histologic characteristics and prognosis. Cancer 72: 1859-1865, 1993. (Pubitemid 23262112)
    • (1993) Cancer , vol.72 , Issue.6 , pp. 1859-1865
    • Kitamoto, M.1    Nakanishi, T.2    Kira, S.3    Kawaguchi, M.4    Nakashio, R.5    Suemori, S.6    Kajiyama, G.7    Asahara, T.8    Dohi, K.9
  • 11
    • 0035270901 scopus 로고    scopus 로고
    • Telomerase activity as a predictive marker for recurrence of hepatocellular carcinoma after hepatectomy
    • DOI 10.1016/S0002-9610(01)00566-9, PII S0002961001005669
    • Kobayashi T, Kubota K, Takayama T and Makuuchi M: Telomerase activity as a predictive marker for recurrence of hepatocellular carcinoma after hepatectomy. Am J Surg 181: 284-288, 2001. (Pubitemid 32480232)
    • (2001) American Journal of Surgery , vol.181 , Issue.3 , pp. 284-288
    • Kobayashi, T.1    Kubota, K.2    Takayama, T.3    Makuuchi, M.4
  • 12
    • 0242525613 scopus 로고    scopus 로고
    • Tissue Factor Expression Correlates with Tumor Angiogenesis and Invasiveness in Human Hepatocellular Carcinoma
    • Poon RT, Lau CP, Ho JW, Yu WC, Fan ST and Wong J: Tissue factor expression correlates with tumor angiogenesis and invasiveness in human hepatocellular carcinoma. Clin Cancer Res 9: 5339-5345, 2003. (Pubitemid 37413589)
    • (2003) Clinical Cancer Research , vol.9 , Issue.14 , pp. 5339-5345
    • Poon, R.T.-P.1    Lau, C.P.-Y.2    Ho, J.W.-Y.3    Yu, W.-C.4    Fan, S.-T.5    Wong, J.6
  • 13
    • 0035132143 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: A prospective study
    • DOI 10.1097/00000658-200102000-00012
    • Poon RT, Ng IO, Lau C, Zhu LX, Yu WC, Lo CM, Fan ST and Wong J: Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study. Ann Surg 233: 227-235, 2001. (Pubitemid 32106077)
    • (2001) Annals of Surgery , vol.233 , Issue.2 , pp. 227-235
    • Poon, R.T.-P.1    Ng, I.O.-L.2    Lau, C.3    Zhu, L.-X.4    Yu, W.-C.5    Lo, C.-M.6    Fan, S.-T.7    Wong, J.8
  • 14
    • 0030272793 scopus 로고    scopus 로고
    • Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis
    • Shen HM and Ong CN: Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis. Mutat Res 366: 23-44, 1996.
    • (1996) Mutat Res , vol.366 , pp. 23-44
    • Shen, H.M.1    Ong, C.N.2
  • 16
    • 0242609884 scopus 로고    scopus 로고
    • Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence
    • DOI 10.1111/j.1349-7006.2003.tb01366.x
    • Uenishi T, Kubo S, Yamamoto T, Shuto T, Ogawa M, Tanaka H, Tanaka S, Kaneda K and Hirohashi K: Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence. Cancer Sci 94: 851-857, 2003. (Pubitemid 37406966)
    • (2003) Cancer Science , vol.94 , Issue.10 , pp. 851-857
    • Uenishi, T.1    Kubo, S.2    Yamamoto, T.3    Shuto, T.4    Ogawa, M.5    Tanaka, H.6    Tanaka, S.7    Kaneda, K.8    Hirohashi, K.9
  • 20
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview - Extensible visualization of microarray data
    • Saldanha AJ: Java Treeview - extensible visualization of microarray data. Bioinformatics 20: 3246-3248, 2004.
    • (2004) Bioinformatics , vol.20 , pp. 3246-3248
    • Saldanha, A.J.1
  • 21
    • 0034650624 scopus 로고    scopus 로고
    • Categorizing a prognostic variable: Review of methods, code for easy implementation and applications to decision-making about cancer treatments
    • DOI 10.1002/(SICI)1097-0258(20000115)19:1<113::AID
    • Mazumdar M and Glassman JR: Categorizing a prognostic variable: review of methods, code for easy implementation and applications to decision-making about cancer treatments. Stat Med 19: 113-132, 2000. (Pubitemid 30051256)
    • (2000) Statistics in Medicine , vol.19 , Issue.1 , pp. 113-132
    • Mazumdar, M.1    Glassman, J.R.2
  • 22
    • 49349109364 scopus 로고    scopus 로고
    • Recent advances in the natural history of hepatocellular carcinoma
    • Trevisani F, Cantarini MC, Wands JR and Bernardi M: Recent advances in the natural history of hepatocellular carcinoma. Carcinogenesis 29: 1299-1305, 2008.
    • (2008) Carcinogenesis , vol.29 , pp. 1299-1305
    • Trevisani, F.1    Cantarini, M.C.2    Wands, J.R.3    Bernardi, M.4
  • 23
    • 84863230667 scopus 로고    scopus 로고
    • BMK1 kinase suppresses epithelial-mesenchymal transition through the Akt/GSK3beta signaling pathway
    • Chen R, Yang Q and Lee JD: BMK1 kinase suppresses epithelial-mesenchymal transition through the Akt/GSK3beta signaling pathway. Cancer Res 72: 1579-1587, 2012.
    • (2012) Cancer Res , vol.72 , pp. 1579-1587
    • Chen, R.1    Yang, Q.2    Lee, J.D.3
  • 25
    • 84855661853 scopus 로고    scopus 로고
    • Activation of PI3 kinase/Akt/HIF-1alpha pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma
    • Jiao M and Nan KJ: Activation of PI3 kinase/Akt/HIF-1alpha pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma. Int J Oncol 40: 461-468, 2012.
    • (2012) Int J Oncol , vol.40 , pp. 461-468
    • Jiao, M.1    Nan, K.J.2
  • 26
    • 84858276094 scopus 로고    scopus 로고
    • Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3beta/snail signalling pathway
    • Maseki S, Ijichi K, Tanaka H, Fujii M, Hasegawa Y, Ogawa T, Murakami S, Kondo E and Nakanishi H: Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3beta/snail signalling pathway. Br J Cancer 106: 1196-1204, 2012.
    • (2012) Br J Cancer , vol.106 , pp. 1196-1204
    • Maseki, S.1    Ijichi, K.2    Tanaka, H.3    Fujii, M.4    Hasegawa, Y.5    Ogawa, T.6    Murakami, S.7    Kondo, E.8    Nakanishi, H.9
  • 27
    • 82355185942 scopus 로고    scopus 로고
    • Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways
    • Ogunwobi OO and Liu C: Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways. Clin Exp Metastasis 28: 721-731, 2011.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 721-731
    • Ogunwobi, O.O.1    Liu, C.2
  • 28
    • 84863116289 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma
    • Ogunwobi OO, Wang T, Zhang L and Liu C: Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma. J Gastroenterol Hepatol 27: 566-578, 2012.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 566-578
    • Ogunwobi, O.O.1    Wang, T.2    Zhang, L.3    Liu, C.4
  • 30
    • 0041333929 scopus 로고    scopus 로고
    • PG490-mediated sensitization of lung cancer cells to Apo2l/TRAIL-induced apoptosis requires activation of ERK2
    • DOI 10.1038/sj.onc.1206842
    • Frese S, Pirnia F, Miescher D, Krajewski S, Borner MM, Reed JC and Schmid RA: PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2. Oncogene 22: 5427-5435, 2003. (Pubitemid 37072197)
    • (2003) Oncogene , vol.22 , Issue.35 , pp. 5427-5435
    • Frese, S.1    Pirnia, F.2    Miescher, D.3    Krajewski, S.4    Borner, M.M.5    Reed, J.C.6    Schmid, R.A.7
  • 31
    • 34848922129 scopus 로고    scopus 로고
    • The hepatitis B virus protein MHBs(t) sensitizes hepatoma cells to TRAIL-induced apoptosis through ERK2
    • DOI 10.1007/s10495-007-0114-4
    • Liang X, Du J, Liu Y, Cui M, Ma C, Han L, Qu Z, Zhang Z, Sun Z, Zhang L, Chen YH and Sun W: The hepatitis B virus protein MHBs(t) sensitizes hepatoma cells to TRAIL-induced apoptosis through ERK2. Apoptosis 12: 1827-1836, 2007. (Pubitemid 47498249)
    • (2007) Apoptosis , vol.12 , Issue.10 , pp. 1827-1836
    • Liang, X.1    Du, J.2    Liu, Y.3    Cui, M.4    Ma, C.5    Han, L.6    Qu, Z.7    Zhang, Z.8    Sun, Z.9    Zhang, L.10    Chen, Y.H.11    Sun, W.12
  • 34
    • 84866005878 scopus 로고    scopus 로고
    • Expression of phosphorylated mTOR and its regulatory protein is related to biological behaviors of ameloblastoma
    • Li N, Zhong M and Song M: Expression of phosphorylated mTOR and its regulatory protein is related to biological behaviors of ameloblastoma. Int J Clin Exp Pathol 5: 660-667, 2012.
    • (2012) Int J Clin Exp Pathol , vol.5 , pp. 660-667
    • Li, N.1    Zhong, M.2    Song, M.3
  • 36
    • 78649630421 scopus 로고    scopus 로고
    • Localisation of phosphorylated mTOR expression is critical to tumour progression and outcomes in patients with endometrial cancer
    • Yoshida Y, Kurokawa T, Horiuchi Y, Sawamura Y, Shinagawa A and Kotsuji F: Localisation of phosphorylated mTOR expression is critical to tumour progression and outcomes in patients with endometrial cancer. Eur J Cancer 46: 3445-3452, 2010.
    • (2010) Eur J Cancer , vol.46 , pp. 3445-3452
    • Yoshida, Y.1    Kurokawa, T.2    Horiuchi, Y.3    Sawamura, Y.4    Shinagawa, A.5    Kotsuji, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.