Statins: Pleiotropic regulators of cardiovascular redox state

Antioxidants and Redox Signaling

Volumn 20, Issue 8, 2014, Pages 1195-1197

  Antoniades, Charalambos ^a   Channon, Keith M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR AGENTS; CARDIOVASCULAR SYSTEM; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; OXIDATION-REDUCTION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

EID: 84894416857     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2014.5836     Document Type: Review

References (9)

1. Adam O and Laufs U. Rac1-mediated effects of HMG-CoA reductase inhibitors (statins) in cardiovascular disease. Antioxid Redox Signal 20: 1238-1250, 2014.
2. Antoniades C, Demosthenous M, Reilly S, Margaritis M, Zhang MH, Antonopoulos A, Marinou K, Nahar K, Jayaram R, Tousoulis D, Bakogiannis C, Sayeed R, Triantafyllou C, Koumallos N, Psarros C, Miliou A, Stefanadis C, Channon KM, and Casadei B. Myocardial redox state predicts inhospital clinical outcome after cardiac surgery effects of short-term pre-operative statin treatment. J Am Coll Cardiol 59: 60-70, 2012.
3. Hermida N and Balligand J-L. Low-density lipoproteincholesterol-induced endothelial dysfunction and oxidative stress: the role of statins. Antioxid Redox Signal 20: 1216-1237, 2014.
4. Lim S, Sakuma I, Quon MJ, and Koh KK. Differential metabolic actions of specific statins: clinical and therapeutic considerations. Antioxid Redox Signal 20: 1286-1299, 2014.
5. Margaritis M, Antonopoulos AS, Digby J, Lee R, Reilly S, Coutinho P, Shirodaria C, Sayeed R, Petrou M, De Silva R, Jalilzadeh S, Demosthenous M, Bakogiannis C, Tousoulis D, Stefanadis C, Choudhury RP, Casadei B, Channon KM, and Antoniades C. Interactions between vascular wall and perivascular adipose tissue reveal novel roles for adiponectin in the regulation of endothelial nitric oxide synthase function in human vessels. Circulation 127: 2209-2221, 2013.
6. Margaritis M, Channon K, and Antoniades C. Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering. Antioxid Redox Signal 20: 1198-1215, 2014.
7. Pinho-Gomes AC, Reilly S, Brandes RP, and Casadei B. Targeting inflammation and oxidative stress in atrial fibrillation: role of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibition with statins. Antioxid Redox Signal 20: 1268-1285, 2014.
8. Sawada N and Liao JK. Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis. Antioxid Redox Signal 20: 1251-1267, 2014.
9. Violi F and Pignatelli P. Statins as regulators of redox signaling in platelets. Antioxid Redox Signal 20: 1300-1312, 2014.