Genetic gains and losses in oral squamous cell carcinoma: Impact on clinical management

Cellular Oncology

Volumn 37, Issue 1, 2014, Pages 29-39

  Ribeiro, Ilda Patrícia ^a   Marques, Francisco ^a,b   Caramelo, Francisco ^a   Pereira, João ^a   Patrício, Miguel ^a   Prazeres, Hugo ^c   Ferrão, José ^a   Julião, Maria José ^b   Castelo Branco, Miguel ^a   De Melo, Joana Barbosa ^a   Baptista, Isabel Poiares ^a   Carreira, Isabel Marques ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^c Instituto Portugues de Oncologia Francisco Gentil Centro Regional de Oncologia de Coimbra SA   (Portugal)

Author keywords

Chromosomal imbalances; Copy number losses and gains; Genetic profile; Oral squamous cell carcinoma

Indexed keywords

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CHROMOSOME ABERRATIONS; DNA COPY NUMBER VARIATIONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; MULTIPLEX POLYMERASE CHAIN REACTION; NEOPLASM STAGING; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; TUMOR MARKERS, BIOLOGICAL;

EID: 84894415658     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-013-0161-5     Document Type: Article

References (53)

1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, M.J. Thun, Cancer statistics, 2009. CA Cancer J. Clin. 59(4), 225-249 (2009)
2. S. Ambatipudi, M. Gerstung, R. Gowda, P. Pai, A.M. Borges, A.A. Schaffer, N. Beerenwinkel, M.B. Mahimkar, Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome. PLoS One 6(2), e17250 (2011)
3. L.P. Kowalski, Results of salvage treatment of the neck in patients with oral cancer. Arch. Otolaryngol. Head Neck Surg. 128(1), 58-62 (2002) (Pubitemid 34052086)
4. S.A. Liu, Y.K. Wong, J.C. Lin, C.K. Poon, K.C. Tung, W.C. Tsai, Impact of recurrence interval on survival of oral cavity squamous cell carcinoma patients after local relapse. Otolaryngol. Head Neck Surg. 136(1), 112-118 (2007) (Pubitemid 46037890)
5. A. Nathanson, K. Ågren, A. Biörklund, M.G. Lind, L. Andréason, M. Anniko, A. Freijd, L. Lejdeborn, S. Kinman, A. Kumlien, A. Köling, J. Lindström, A. Novik, J. Olofsson, K.-L. Pettersson, Evaluation of some prognostic factors in small squamous cell carcinoma of the mobile tongue: a multicenter study in Sweden. Head Neck 11(5), 387-392 (1989) (Pubitemid 19210517)
6. W.R. Rate, P. Garrett, R. Hamaker, M. Singer, N. Pugh, D. Ross, R. Haerr, G. Charles, Intraoperative radiation therapy for recurrent head and neck cancer. Cancer 67(11), 2738-2740 (1991)
7. W. Wang, S. Han, Z. Yao, X. Li, P. Huang, M. Zhang, Y. Chen, J. He, A study of epidemiologic and recurrence factors of oral cancer. J. Oral Maxillofac. Surg. (2011)
8. L.Y. Wong, W.I. Wei, L.K. Lam, A.P. Yuen, Salvage of recurrent head and neck squamous cell carcinoma after primary curative surgery. Head Neck 25(11), 953-959 (2003) (Pubitemid 37323011)
9. B.J. Braakhuis, R.H. Brakenhoff, C.R. Leemans, Second field tumors: a new opportunity for cancer prevention? Oncologist 10(7), 493-500 (2005) (Pubitemid 41266330)
10. D. Weiss, C. Stockmann, K. Schrodter, C. Rudack, Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma. Cell Oncol (Dordr) 36(3), 213-224 (2013)
11. M.A. Guervos, C.A. Marcos, M. Hermsen, A.S. Nuno, C. Suarez, J.L. Llorente, Deletions of N33, STK11 and TP53 are involved in the development of lymph node metastasis in larynx and pharynx carcinomas. Cell. Oncol. 29(4), 327-334 (2007) (Pubitemid 47037246)
12. C. Wittekind, F.L. Greene, R.V.P. Hutter, M. Klimpfinger, L.H. Sobin, TNM atlas. Illustrated Guide to the TNM/pTNM Classification of Malignant Tumours, 5th edn. (UICC), I.U.A.C., (Springer-Verlag, Berlin-Heidelberg-New York, 2003)
13. J.P. Schouten, C.J. McElgunn, R. Waaijer, D. Zwijnenburg, F. Diepvens, G. Pals, Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification. Nucleic Acids Res. 30(12), e57 (2002)
14. R.J. Nobre, E. Cruz, O. Real, L.P. de Almeida, T.C. Martins, Characterization of common and rare human papillomaviruses in Portuguese women by the polymerase chain reaction, restriction fragment length polymorphism and sequencing. J. Med. Virol. 82(6), 1024-1032 (2010)
15. N.L. Barnes, S. Khavari, G.P. Boland, A. Cramer, W.F. Knox, N.J. Bundred, Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breast. Clin. Cancer Res. 11(6), 2163-2168 (2005) (Pubitemid 40490173)
16. K. Freier, C. Hofele, K. Knoepfle, M. Gross, F. Devens, G. Dyckhoff, P. Plinkert, P. Lichter, C. Herold-Mende, Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes. J. Oral Pathol. Med. 39(5), 382-389 (2010)
17. B. Singh, S.K. Gogineni, P.G. Sacks, A.R. Shaha, J.P. Shah, A. Stoffel, P.H. Rao, Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification. Cancer Res. 61(11), 4506-4513 (2001) (Pubitemid 32685781)
18. C.A. Marcos, M. Alonso-Guervos, N.R. Prado, T.S. Gimeno, F.D. Iglesias, M. Hermsen, J.L. Llorente, Genetic model of transformation and neoplastic progression in laryngeal epithelium. Head Neck 33(2), 216-224 (2010)
19. N. Uzawa, D. Akanuma, A. Negishi, H. Iwaki, Y. Uzawa, T. Amagasa, M.A. Yoshida, Homozygous deletions on the short arm of chromosome 3 in human oral squamous cell carcinomas. Oral Oncol. 37(4), 351-356 (2001) (Pubitemid 32391381)
20. M.A. Pershouse, A.K. El-Naggar, K. Hurr, H. Lin, W.K. Yung, P.A. Steck, Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma. Oncogene 14(3), 369-373 (1997) (Pubitemid 27073092)
21. X.L. Wang, K. Uzawa, F.L. Imai, H. Tanzawa, Localization of a novel tumor suppressor gene associated with human oral cancer on chromosome 4q25. Oncogene 18(3), 823-825 (1999) (Pubitemid 29080341)
22. E.J. Mao, S.M. Schwartz, J.R. Daling, A.M. Beckmann, Loss of heterozygosity at 5q21-22 (adenomatous polyposis coli gene region) in oral squamous cell carcinoma is common and correlated with advanced disease. J. Oral Pathol. Med. 27(7), 297-302 (1998) (Pubitemid 28382635)
23. R.A. Brekken, J.P. Overholser, V.A. Stastny, J. Waltenberger, J.D. Minna, P.E. Thorpe, Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice. Cancer Res. 60(18), 5117-5124 (2000)
24. L.C. da Silva Veiga, N.A. Bergamo, P.P. dos Reis, L.P. Kowalski, S.R. Rogatto, DNA gains at 8q23.2: a potential early marker in head and neck carcinomas. Cancer Genet. Cytogenet. 146(2), 110-115 (2003) (Pubitemid 37211308)
25. S.C. Lin, Y.J. Chen, S.Y. Kao, M.T. Hsu, C.H. Lin, S.C. Yang, T.Y. Liu, K.W. Chang, Chromosomal changes in betel-associated oral squamous cell carcinomas and their relationship to clinical parameters. Oral Oncol. 38(3), 266-273 (2002) (Pubitemid 34442548)
26. C. Garnis, B.P. Coe, A. Ishkanian, L. Zhang, M.P. Rosin, W.L. Lam, Novel regions of amplification on 8q distinct from the MYC locus and frequently altered in oral dysplasia and cancer. Gene Chromosome Cancer 39(1), 93-98 (2004) (Pubitemid 37475258)
27. C. Garnis, B.P. Coe, L. Zhang, M.P. Rosin, W.L. Lam, Overexpression of LRP12, a gene contained within an 8q22 amplicon identified by high-resolution array CGH analysis of oral squamous cell carcinomas. Oncogene 23(14), 2582-2586 (2004) (Pubitemid 38520756)
28. J.D. Cha, H.J. Kim, I.H. Cha, Genetic alterations in oral squamous cell carcinoma progression detected by combining array-based comparative genomic hybridization and multiplex ligation-dependent probe amplification. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 111(5), 594-607 (2011)
29. S.M. Gollin, Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. Head Neck 23(3), 238-253 (2001) (Pubitemid 32193221)
30. A. Sparano, K.M. Quesnelle, M.S. Kumar, Y. Wang, A.J. Sylvester, M. Feldman, D.A. Sewell, G.S. Weinstein, M.S. Brose, Genome-wide profiling of oral squamous cell carcinoma by array-based comparative genomic hybridization. Laryngoscope 116(5), 735-741 (2006) (Pubitemid 44318029)
31. S.L. Cooke, J.C. Pole, S.F. Chin, I.O. Ellis, C. Caldas, P.A. Edwards, High-resolution array CGH clarifies events occurring on 8p in carcinogenesis. BMC Cancer 8, 288 (2008)
32. M.J. Worsham, G. Pals, J.P. Schouten, R.M. Van Spaendonk, A. Concus, T.E. Carey, M.S. Benninger, Delineating genetic pathways of disease progression in head and neck squamous cell carcinoma. Arch. Otolaryngol. Head Neck Surg. 129(7), 702-708 (2003) (Pubitemid 36858953)
33. J.W. Rocco, D. Sidransky, p16(MTS-1/CDKN2/INK4a) in cancer progression. Exp. Cell Res. 264(1), 42-55 (2001) (Pubitemid 32989080)
34. P. van der Riet, H. Nawroz, R.H. Hruban, R. Corio, K. Tokino, W. Koch, D. Sidransky, Frequent loss of chromosome 9p21-22 early in head and neck cancer progression. Cancer Res. 54(5), 1156-1158 (1994) (Pubitemid 24108049)
35. C. Jin, Y. Jin, D. Gisselsson, J. Wennerberg, T.S. Wah, B. Stromback, Y.L. Kwong, F. Mertens, Molecular cytogenetic characterization of the 11q13 amplicon in head and neck squamous cell carcinoma. Cytogenet Genome Res 115(2), 99-106 (2006) (Pubitemid 44622514)
36. R.A. Parikh, J.S. White, X. Huang, D.W. Schoppy, B.E. Baysal, R. Baskaran, C.J. Bakkenist, W.S. Saunders, L.C. Hsu, M. Romkes, S.M. Gollin, Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma. Gene Chromosome Cancer 46(8), 761-775 (2007) (Pubitemid 46912347)
37. K. Freier, C. Sticht, C. Hofele, C. Flechtenmacher, D. Stange, L. Puccio, G. Toedt, B. Radlwimmer, P. Lichter, S. Joos, Recurrent coamplification of cytoskeleton-associated genes EMS1 and SHANK2 with CCND1 in oral squamous cell carcinoma. Gene Chromosome Cancer 45(2), 118-125 (2006) (Pubitemid 43191018)
38. H. Mineta, K. Miura, S. Takebayashi, Y. Ueda, K. Misawa, H. Harada, J. Wennerberg, M. Dictor, Cyclin D1 overexpression correlates with poor prognosis in patients with tongue squamous cell carcinoma. Oral Oncol. 36(2), 194-198 (2000) (Pubitemid 30169162)
39. A. Namazie, S. Alavi, O.I. Olopade, G. Pauletti, N. Aghamohammadi, M. Aghamohammadi, J.A. Gornbein, T.C. Calcaterra, D.J. Slamon, M.B. Wang, E.S. Srivatsan, Cyclin D1 amplification and p16(MTS1/CDK4I) deletion correlate with poor prognosis in head and neck tumors. Laryngoscope 112(3), 472-481 (2002) (Pubitemid 34225863)
40. Z. Yu, P.M. Weinberger, B.G. Haffty, C. Sasaki, C. Zerillo, J. Joe, D. Kowalski, J. Dziura, R.L. Camp, D.L. Rimm, A. Psyrri, Cyclin D1 is a valuable prognostic marker in oropharyngeal squamous cell carcinoma. Clin. Cancer Res. 11(3), 1160-1166 (2005) (Pubitemid 40175766)
41. U. Duvvuri, D.J. Shiwarski, D. Xiao, C. Bertrand, X. Huang, R.S. Edinger, J.R. Rock, B.D. Harfe, B.J. Henson, K. Kunzelmann, R. Schreiber, R.S. Seethala, A.M. Egloff, X. Chen, V.W. Lui, J.R. Grandis, S.M. Gollin, TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res. 72(13), 3270-3281 (2012)
42. O. Nilsson, Profiling of ileal carcinoids. Neuroendocrinology 97(1), 7-18 (2013)
43. M.H. Mossink, A. van Zon, R.J. Scheper, P. Sonneveld, E.A. Wiemer, Vaults: a ribonucleoprotein particle involved in drug resistance? Oncogene 22(47), 7458-7467 (2003) (Pubitemid 37487169)
44. N. Pecina-Slaus, M. Kljaic, T. Nikuseva-Martic, Loss of heterozygosity of APC and CDH1 genes in laryngeal squamous cell carcinoma. Pathol. Res. Pract. 201(8-9), 557-563 (2005) (Pubitemid 41363949)
45. D. Hardisson, C. Alvarez-Marcos, A. Salas-Bustamante, M. Alonso-Guervos, N. Sastre, A. Sampedro, Numerical aberrations of chromosomes 8, 9, 11, and 17 in squamous cell carcinoma of the pharynx and larynx: a fluorescence in situ hybridization and DNA flow cytometric analysis of 50 cases. Oral Oncol. 40(4), 409-417 (2004) (Pubitemid 38221388)
46. C. Scully, J.K. Field, H. Tanzawa, Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle control. Oral Oncol. 36(3), 256-263 (2000) (Pubitemid 30227706)
47. A. Carneiro, A. Isinger, A. Karlsson, J. Johansson, G. Jonsson, P.O. Bendahl, D. Falkenback, B. Halvarsson, M. Nilbert, Prognostic impact of array-based genomic profiles in esophageal squamous cell cancer. BMC Cancer 8, 98 (2008) (Pubitemid 351663390)
48. C.L. Martin, S.C. Reshmi, T. Ried, W. Gottberg, J.W. Wilson, J.K. Reddy, P. Khanna, J.T. Johnson, E.N. Myers, S.M. Gollin, Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature. Oral Oncol. 44(4), 369-382 (2008) (Pubitemid 351380982)
49. B.J.M. Braakhuis, E. Bloemena, C.R. Leemans, R.H. Brakenhoff, Molecular analysis of surgical margins in head and neck cancer: more than a marginal issue. Oral Oncol. 46(7), 485-491 (2010)
50. J. Califano, P. van der Riet, W. Westra, H. Nawroz, G. Clayman, S. Piantadosi, R. Corio, D. Lee, B. Greenberg, W. Koch, D. Sidransky, Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res. 56(11), 2488-2492 (1996) (Pubitemid 26170679)
51. A. Bahl, P. Kumar, L. Dar, B.K. Mohanti, A. Sharma, A. Thakar, V. Karthikeyan, K. Sikka, C. Singh, K. Poo, J. Lodha, Prevalence and trends of human papillomavirus in oropharyngeal cancer in a predominantly north Indian population. Head Neck, (2013)
52. M.L. Gillison, Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity. Semin. Oncol. 31(6), 744-754 (2004) (Pubitemid 39602680)
53. C.R. Leemans, B.J. Braakhuis, R.H. Brakenhoff, The molecular biology of head and neck cancer. Nat. Rev. Cancer 11(1), 9-22 (2011)