An outbreak of CTX-M-15 -producing Escherichia coli, Enterobacter cloacae, and Klebsiella in a children's hospital in Finland

Scandinavian Journal of Infectious Diseases

Volumn 46, Issue 3, 2014, Pages 225-230

  Pasanen, Tanja ^a   Jalava, Jari ^b   Horsma, Jenni ^a   Salo, Eeva ^c   Pakarinen, Mikko ^c   Tarkka, Eveliina ^a   Vaara, Martti ^a   Tissari, Päivi ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c UNIVERSITY OF HELSINKI AND HELSINKI UNIVERSITY HOSPITAL   (Finland)

Author keywords

Enterobacter cloacae; Escherichia coli; Extended spectrum beta lactamase; Repetitive extragenic palindromic PCR

Indexed keywords

BETA-LACTAMASES; CHILD; DISEASE OUTBREAKS; ELECTROPHORESIS, GEL, PULSED-FIELD; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; FINLAND; HOSPITALS, PEDIATRIC; HUMANS;

EID: 84894381150     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2013.857045     Document Type: Article

References (21)

1. Pitout JD, Laupland KB. Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern. Lancet Infect Dis 2008;8:159-66.
2. Paterson DL, Bonomo RA. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 2005; 18:657-86.
3. Livermore DM, Hawkey PM. CTX-M: changing the face of ESBLs in the UK. J Antimicrob Chemother 2005;56:451-4.
4. Pfaller MA, Segreti J. Overview of the epidemiological profile and laboratory detection of extended-spectrum beta-lactamases. Clin Infect Dis 2006;42:S153-63.
5. Giske CG, Sundsfjord AS, Kahlmeter G, Woodford N, Nordmann P, Paterson DL, et al. Redefining extended-spectrum beta-lactamases: balancing science and clinical need. J Antimicrob Chemother 2009;63:1-4.
6. van Belkum A, Struelens M, de Visser A, Verbrugh H, Tibayrenc M. Role of genomic typing in taxonomy, evolutionary genetics, and microbial epidemiology. Clin Microbiol Rev 2001;14:547-60.
7. Healy M, Huong J, Bittner T, Lising M, Frye S, Raza S, et al. Microbial DNA typing by automated repetitive-sequence-based PCR. J Clin Microbiol 2005;43:199-207.
8. Deplano A, Denis O, Rodriguez-Villalobos H, De Ryck R, Struelens MJ, Hallin M. Controlled performance evaluation of the DiversiLab repetitive-sequence-based genotyping system for typing multidrug-resistant health care-associated bacterial pathogens . J Clin Microbiol 2011;49:3616-20.
9. Lau SH, Cheesborough J, Kaufmann ME, Woodford N, Dodgson AR, Dodgson KJ, et al. Rapid identification of uropathogenic Escherichia coli of the O25:H4-ST131 clonal lineage using the DiversiLab repetitive sequence-based PCR system. Clin Microbiol Infect 2010;16:232-7.
10. Fluit AC, Terlingen AM, Andriessen L, Ikawaty R, van Mansfeld R, Top J, et al. Evaluation of the DiversiLab system for detection of hospital outbreaks of infections by different bacterial species. J Clin Microbiol 2010;48:3979-89.
11. Ligozzi M, Fontana R, Aldegheri M, Scalet G, Lo Cascio G. Comparative evaluation of an automated repetitive-sequence-based PCR instrument versus pulsed-field gel electrophoresis in the setting of a Serratia marcescens nosocomial infection outbreak. J Clin Microbiol 2010;48:1690-5.
12. Brolund A, Haeggman S, Edquist PJ, Gezelius L, Olsson-Liljequist B, Wisell KT, et al. The DiversiLab system versus pulsed-field gel electrophoresis: characterisation of extended spectrum beta-lactamase producing Escherichia coli and Klebsiella pneumoniae. J Microbiol Methods 2010;83:224-30.
13. Potz NA, Colman M, Warner M, Reynolds R, Livermore DM. False-positive extended-spectrum beta-lactamase tests for Klebsiella oxytoca strains hyperproducing K1 beta-lactamase. J Antimicrob Chemother 2004;53:545-7.
14. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk susceptibility tests; approved standard. Document M2-A8. Wayne, PA: CLSI; 2003.
15. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk susceptibility tests; approved standard. Document M2-A9. Wayne, PA: CLSI; 2006.
16. Nyberg SD, Osterblad M, Hakanen AJ, Huovinen P, Jalava J, Resistance TF. Detection and molecular genetics of extended-spectrum beta-lactamases among cefuroxime-resistant Escherichia coli and Klebsiella spp. isolates from Finland, 2002-2004. Scand J Infect Dis 2007;39:417-24.
17. Forssten SD, Kolho E, Lauhio A, Lehtola L, Mero S, Oksaharju A, et al. Emergence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae during the years 2000 and 2004 in Helsinki, Finland. Clin Microbiol Infect 2010;16:1158-61.
18. Pallecchi L, Bartoloni A, Fiorelli C, Mantella A, Di Maggio T, Gamboa H, et al. Rapid dissemination and diversity of CTX-M extended-spectrum beta-lactamase genes in commensal Escherichia coli isolates from healthy children from low-resource settings in Latin America. Antimicrob Agents Chemother 2007;51:2720-5.
19. Johnson JR, Clabots C, Kuskowski MA. Multiple-host sharing, long-term persistence, and virulence of Escherichia coli clones from human and animal household members. J Clin Microbiol 2008;46:4078-82.
20. Harris AD, Kotetishvili M, Shurland S, Johnson JA, Morris JG, Nemoy LL, et al. How important is patient-to-patient transmission in extended-spectrum beta-lactamase Escherichia coli acquisition. Am J Infect Control 2007;35: 97-101.
21. Harris AD, Perencevich EN, Johnson JK, Paterson DL, Morris JG, Strauss SM, et al. Patient-to-patient transmission is important in extended-spectrum beta-lactamase-producing Klebsiella pneumoniae acquisition. Clin Infect Dis 2007; 45:1347-50.