Early microvascular changes with loss of the glycocalyx in children with type 1 diabetes

Journal of Pediatrics

Volumn 164, Issue 3, 2014, Pages

  Nussbaum, Claudia ^a   Cavalcanti Fernandes Heringa, Ana ^a   Mormanova, Zuzana ^a   Puchwein Schwepcke, Alexandra F ^a   Bechtold Dalla Pozza, Susanne ^a   Genzel Boroviczény, Orsolya ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C;

ADOLESCENT; ARTICLE; BLOOD FLOW; BLOOD VESSEL DIAMETER; BODY MASS; CAPILLARY; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DENSITY; DIABETIC MICROANGIOPATHY; DISEASE DURATION; FEMALE; GLUCOSE BLOOD LEVEL; GLYCOCALYX; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MICROCIRCULATION; MICROVASCULATURE; PRIORITY JOURNAL; SCHOOL CHILD; THICKNESS;

ADOLESCENT; BLOOD GLUCOSE; CAPILLARIES; CASE-CONTROL STUDIES; CHILD; DIABETES MELLITUS, TYPE 1; ENDOTHELIUM, VASCULAR; FEMALE; GLYCOCALYX; HUMANS; MALE; MICROCIRCULATION; MICROVESSELS; MOUTH FLOOR;

EID: 84894361693     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2013.11.016     Document Type: Article

References (28)

1. D. Daneman Type 1 diabetes Lancet 367 2006 847 858
2. C.G. Schalkwijk, and C.D. Stehouwer Vascular complications in diabetes mellitus: the role of endothelial dysfunction Clin Sci (Lond) 109 2005 143 159
3. F. Khan, T.A. Elhadd, S.A. Greene, and J.J. Belch Impaired skin microvascular function in children, adolescents, and young adults with type 1 diabetes Diabetes Care 23 2000 215 220
4. G.S. Babar, H. Zidan, M.E. Widlansky, E. Das, R.G. Hoffmann, and M. Daoud et al. Impaired endothelial function in preadolescent children with type 1 diabetes Diabetes Care 34 2011 681 685
5. T.A. Elhadd, G. Kennedy, A. Hill, M. Mclaren, R.W. Newton, and S.A. Greene et al. Abnormal markers of endothelial cell activation and oxidative stress in children, adolescents and young adults with type 1 diabetes with no clinical vascular disease Diabetes Metab Res Rev 15 1999 405 411
6. M.J. Jarvisalo, M. Raitakari, J.O. Toikka, A. Putto-Laurila, R. Rontu, and S. Laine et al. Endothelial dysfunction and increased arterial intima-media thickness in children with type 1 diabetes Circulation 109 2004 1750 1755
7. R. Dalla Pozza, H. Netz, H.P. Schwarz, and S. Bechtold Subclinical atherosclerosis in diabetic children: results of a longitudinal study Pediatr Diabetes 11 2010 129 133
8. U. Hink, H. Li, H. Mollnau, M. Oelze, E. Matheis, and M. Hartmann et al. Mechanisms underlying endothelial dysfunction in diabetes mellitus Circ Res 88 2001 E14 E22
9. Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study JAMA 290 2003 2159 2167
10. The Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group N Engl J Med 329 1993 977 986
11. A.H. Salmon, and S.C. Satchell Endothelial glycocalyx dysfunction in disease: albuminuria and altered microvascular permeability J Pathol 226 2011 562 574
12. S. Reitsma, D.W. Slaaf, H. Vink, M.A. van Zandvoort, and M.G. oude Egbrink The endothelial glycocalyx: composition, functions, and visualization Pflugers Arch 454 2007 345 359
13. J.B. Brower, J.H. Targovnik, M.R. Caplan, and S.P. Massia High glucose-mediated loss of cell surface heparan sulfate proteoglycan impairs the endothelial shear stress response Cytoskeleton (Hoboken) 67 2010 135 141
14. M. Nieuwdorp, T.W. van Haeften, M.C. Gouverneur, H.L. Mooij, M.H. van Lieshout, and M. Levi et al. Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo Diabetes 55 2006 480 486
15. M. Nieuwdorp, F. Holleman, G.E. de, H. Vink, J. Gort, and A. Kontush et al. Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis Diabetologia 50 2007 1288 1293
16. S. Hiedl, A. Schwepcke, F. Weber, and O. Genzel-Boroviczeny Microcirculation in preterm infants: profound effects of patent ductus arteriosus J Pediatr 156 2010 191 196
17. M. Nieuwdorp, M.C. Meuwese, H.L. Mooij, C. Ince, L.N. Broekhuizen, and J.J. Kastelein et al. Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability J Appl Physiol 104 2008 845 852
18. M. Nieuwdorp, H.L. Mooij, J. Kroon, B. Atasever, J.A. Spaan, and C. Ince et al. Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes Diabetes 55 2006 1127 1132
19. L.N. Broekhuizen, B.A. Lemkes, H.L. Mooij, M.C. Meuwese, H. Verberne, and F. Holleman et al. Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus Diabetologia 53 2010 2646 2655
20. C.J. Zuurbier, C. Demirci, A. Koeman, H. Vink, and C. Ince Short-term hyperglycemia increases endothelial glycocalyx permeability and acutely decreases lineal density of capillaries with flowing red blood cells J Appl Physiol 99 2005 1471 1476
21. A. Singh, V. Friden, I. Dasgupta, R.R. Foster, G.I. Welsh, and J.E. Tooke et al. High glucose causes dysfunction of the human glomerular endothelial glycocalyx Am J Physiol Renal Physiol 300 2011 F40 F48
22. L. Monnier, E. Mas, C. Ginet, F. Michel, L. Villon, and J.P. Cristol et al. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes JAMA 295 2006 1681 1687
23. M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
24. G. Llaurado, V. Ceperuelo-Mallafre, C. Vilardell, R. Simo, N. Freixenet, and J. Vendrell et al. Arterial stiffness is increased in patients with type 1 diabetes without cardiovascular disease: a potential role of low-grade inflammation Diabetes Care 35 2012 1083 1089
25. P. Algenstaedt, C. Schaefer, T. Biermann, A. Hamann, B. Schwarzloh, and H. Greten et al. Microvascular alterations in diabetic mice correlate with level of hyperglycemia Diabetes 52 2003 542 549
26. J. Koscielny, R. Latza, S. Wolf, H. Kiesewetter, and F. Jung Early rheological and microcirculatory changes in children with type I diabetes mellitus Clin Hemorheol Microcirc 19 1998 139 150
27. R.N. Pittman Oxygen transport and exchange in the microcirculation Microcirculation 12 2005 59 70
28. G. Gambaro, I. Kinalska, A. Oksa, P. Pont'uch, M. Hertlova, and J. Olsovsky et al. Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: the Di.N.A.S. randomized trial J Am Soc Nephrol 13 2002 1615 1625