Effect of esomeprazole versus placebo on pulmonary exacerbations in cystic fibrosis

BMC Pulmonary Medicine

Volumn 14, Issue 1, 2014, Pages

  DiMango, Emily ^a   Walker, Patricia ^b   Keating, Claire ^a   Berdella, Maria ^b   Robinson, Newell ^a   Langfelder Schwind, Elinor ^b   Levy, Diane ^c   Liu, Xinhua ^c  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^b BETH ISRAEL MEDICAL CENTER   (United States)

^c Mailman School of Public Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; CYSTIC FIBROSIS; DISEASE PROGRESSION; DOUBLE-BLIND METHOD; ESOMEPRAZOLE; FEMALE; GASTROESOPHAGEAL REFLUX; HUMANS; LUNG DISEASES; MALE; PROTON PUMP INHIBITORS;

EID: 84894279608     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/1471-2466-14-21     Document Type: Article

References (35)

1. Gustafsson PM, Fransson SG, Kjellman NI, Tibbling L. Gastro-oesophageal reflux and severity of pulmonary disease in cystic fibrosis. Scand J Gastroenterol 1991, 26(5):449-456. PubMed PMID: 1871537, 10.3109/00365529108998565, 1871537.
2. Palm K, Sawicki G, Rosen R. The impact of reflux burden on Pseudomonas positivity in children with cystic fibrosis. Pediatr Pulmonol 2012, 47(6):582-587. PubMed PMID: 22162484, 10.1002/ppul.21598, 22162484.
3. Ledson MJ, Tran J, Walshaw MJ. Prevalence and mechanisms of gastro-oesophageal reflux in adult cystic fibrosis patients. J R Soc Med 1998, 91(1):7-9. PubMed PMID: 9536132.
4. Vic P, Tassin E, Turck D, Gottrand F, Launay V, Farriaux JP. [Frequency of gastroesophageal reflux in infants and in young children with cystic fibrosis]. Arch Pediatr 1995, 2(8):742-746. PubMed PMID: 7550838. Frequence du reflux gastrooesophagien chez le nourrisson et le jeune enfant atteints de mucoviscidose, 10.1016/0929-693X(96)81243-7, 7550838.
5. Button BM, Roberts S, Kotsimbos TC, Levvey BJ, Williams TJ, Bailey M, et al. Gastroesophageal reflux (symptomatic and silent): a potentially significant problem in patients with cystic fibrosis before and after lung transplantation. J Heart Lung Transplant 2005, 24(10):1522-1529. PubMed PMID: 16210125, 10.1016/j.healun.2004.11.312, 16210125.
6. D'Ovidio F, Singer LG, Hadjiliadis D, Pierre A, Waddell TK, de Perrot M, et al. Prevalence of gastroesophageal reflux in end-stage lung disease candidates for lung transplant. Ann Thorac Surg 2005, 80(4):1254-1260. PubMed PMID: 16181849, 10.1016/j.athoracsur.2005.03.106, 16181849.
7. Cystic Fibrosis Foundation Patient Registry 2010 Annual Data Report Bethesda M, http://www.cff.org/SearchResults/index.cfm?cx=014097933530442145544%3Amfnlnb3cjhe&q=annual+report+2010., Cystic Fibrosis Foundation Patient Registry.
8. Navarro J, Rainisio M, Harms HK, Hodson ME, Koch C, Mastella G, et al. Factors associated with poor pulmonary function: cross-sectional analysis of data from the ERCF. European Epidemiologic Registry of Cystic Fibrosis. Eur Respir J 2001, 18(2):298-305. PubMed PMID: 11529288, 10.1183/09031936.01.00068901, 11529288.
9. Button BM, Heine RG, Catto-Smith AG, Olinsky A, Phelan PD, Ditchfield MR, et al. Chest physiotherapy in infants with cystic fibrosis: to tip or not? A five-year study. Pediatr Pulmonol 2003, 35(3):208-213. PubMed PMID: 12567389, 10.1002/ppul.10227, 12567389.
10. Sheikh SI, Ryan-Wenger NA, McCoy KS. Outcomes of surgical management of severe GERD in patients with cystic fibrosis. Pediatr Pulmonol 2012, PubMed PMID: 22949398.
11. Mastronarde JG, Anthonisen NR, Castro M, Holbrook JT, Leone FT, , et al. American Lung Association Asthma Clinical Research C Efficacy of esomeprazole for treatment of poorly controlled asthma. New Engl J Med 2009, 360(15):1487-1499. PubMed PMID: 19357404. Pubmed Central PMCID: 2974569, 2974569, 19357404, American Lung Association Asthma Clinical Research C.
12. Kiljander TO, Harding SM, Field SK, Stein MR, Nelson HS, Ekelund J, et al. Effects of esomeprazole 40 mg twice daily on asthma: a randomized placebo-controlled trial. Am J Respir Crit Care Med 2006, 173(10):1091-1097. PubMed PMID: 16357331, 10.1164/rccm.200507-1167OC, 16357331.
13. Raghu G, Yang ST, Spada C, Hayes J, Pellegrini CA. Sole treatment of acid gastroesophageal reflux in idiopathic pulmonary fibrosis: a case series. Chest 2006, 129(3):794-800. PubMed PMID: 16537884, 10.1378/chest.129.3.794, 16537884.
14. Lee JS, Ryu JH, Elicker BM, Lydell CP, Jones KD, Wolters PJ, et al. Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011, 184(12):1390-1394. PubMed PMID: 21700909, 10.1164/rccm.201101-0138OC, 3262030, 21700909.
15. Eurich DT, Sadowski CA, Simpson SH, Marrie TJ, Majumdar SR. Recurrent community-acquired pneumonia in patients starting acid-suppressing drugs. Am J Med 2010, 123(1):47-53. PubMed PMID: 20102991, 10.1016/j.amjmed.2009.05.032, 20102991.
16. Hermos JA, Young MM, Fonda JR, Gagnon DR, Fiore LD, Lawler EV. Risk of community-acquired pneumonia in veteran patients to whom proton pump inhibitors were dispensed. Clin Infect Dis 2012, 54(1):33-42. PubMed PMID: 22100573, 10.1093/cid/cir767, 22100573.
17. de Jager CP, Wever PC, Gemen EF, van Oijen MG, van Gageldonk-Lafeber AB, Siersema PD, et al. Proton pump inhibitor therapy predisposes to community-acquired Streptococcus pneumoniae pneumonia. Aliment Pharmacol Therapeut 2012, 36(10):941-949. PubMed PMID: 23034135.
18. Meijvis SC, Cornips MC, Voorn GP, Souverein PC, Endeman H, Biesma DH, et al. Microbial evaluation of proton-pump inhibitors and the risk of pneumonia. Eur Respir J 2011, 38(5):1165-1172. PubMed PMID: 21478217, 10.1183/09031936.00020811, 21478217.
19. Gray SL, LaCroix AZ, Larson J, Robbins J, Cauley JA, Manson JE, et al. Proton pump inhibitor use, hip fracture, and change in bone mineral density in postmenopausal women: results from the women's health initiative. Arch Intern Med 2010, 170(9):765-771. PubMed PMID: 20458083, 10.1001/archinternmed.2010.94, 20458083.
20. Lau YT, Ahmed NN. Fracture risk and bone mineral density reduction associated with proton pump inhibitors. Pharmacotherapy 2012, 32(1):67-79. PubMed PMID: 22392829, 10.1002/PHAR.1007, 22392829.
21. Richter JE, Kahrilas PJ, Johanson J, Maton P, Breiter JR, Hwang C, et al. Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial. Am J Gastroenterol 2001, 96(3):656-665. PubMed PMID: 11280530, 10.1111/j.1572-0241.2001.03600.x, 11280530.
22. DeMeester TR, Johnson LF. The evaluation of objective measurements of gastroesophageal reflux and their contribution to patient management. Surg Clin North Am 1976, 56(1):39-53. PubMed PMID: 2983.
23. Quittner AL, Buu A, Messer MA, Modi AC, Watrous M. Development and validation of the cystic fibrosis questionnaire in the United States: a health-related quality-of-life measure for cystic fibrosis. Chest 2005, 128(4):2347-2354. PubMed PMID: 16236893, 10.1378/chest.128.4.2347, 16236893.
24. Damiano A, Handley K, Adler E, Siddique R, Bhattacharyja A. Measuring symptom distress and health-related quality of life in clinical trials of gastroesophageal reflux disease treatment: further validation of the Gastroesophageal Reflux Disease Symptom Assessment Scale (GSAS). Dig Dis Sci 2002, 47(7):1530-1537. PubMed PMID: 12141813, 10.1023/A:1015815102175, 12141813.
25. Pauwels A, Decraene A, Blondeau K, Mertens V, Farre R, Proesmans M, et al. Bile acids in sputum and increased airway inflammation in patients with cystic fibrosis. Chest 2012, 141(6):1568-1574. PubMed PMID: 22135379, 10.1378/chest.11-1573, 22135379.
26. Mendez BM, Davis CS, Weber C, Joehl RJ, Fisichella PM. Gastroesophageal reflux disease in lung transplant patients with cystic fibrosis. Am J Surg 2012, 204(5):e21-e26. PubMed PMID: 22921151, 10.1016/j.amjsurg.2012.07.019, 22921151.
27. Ledson MJ, Wilson GE, Tran J, Walshaw MJ. Tracheal microaspiration in adult cystic fibrosis. J R Soc Med 1998, 91(1):10-12. PubMed PMID: 9536133, 1296416, 9536133.
28. Hamamoto J, Kohrogi H, Kawano O, Iwagoe H, Fujii K, Hirata N, et al. Esophageal stimulation by hydrochloric acid causes neurogenic inflammation in the airways in guinea pigs. J Appl Physiol 1997, 82(3):738-745. PubMed PMID: 9074957.
29. Carpagnano GE, Resta O, Ventura MT, Amoruso AC, Di Gioia G, Giliberti T, et al. Airway inflammation in subjects with gastro-oesophageal reflux and gastro-oesophageal reflux-related asthma. J Intern Med 2006, 259(3):323-331. PubMed PMID: 16476110, 10.1111/j.1365-2796.2005.01611.x, 16476110.
30. Davis RD, Lau CL, Eubanks S, Messier RH, Hadjiliadis D, Steele MP, et al. Improved lung allograft function after fundoplication in patients with gastroesophageal reflux disease undergoing lung transplantation. J Thorac Cardiovasc Surg 2003, 125(3):533-542. PubMed PMID: 12658195, 10.1067/mtc.2003.166, 12658195.
31. Tamhankar AP, Peters JH, Portale G, Hsieh CC, Hagen JA, Bremner CG, et al. Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technology. J Gastrointest Surg: Offic J Soc Surg Aliment Tract 2004, 8(7):890-897. discussion 7-8. PubMed PMID: 15531244.
32. Doumit M, Krishnan U, Jaffe A, Belessis Y. Acid and non-acid reflux during physiotherapy in young children with cystic fibrosis. Pediatr Pulmonol 2012, 47(2):119-124. PubMed PMID: 22241570, 10.1002/ppul.21524, 22241570.
33. Brodzicki J, Trawinska-Bartnicka M, Korzon M. Frequency, consequences and pharmacological treatment of gastroesophageal reflux in children with cystic fibrosis. Med Sci Monit 2002, 8(7):CR529-CR537. PubMed PMID: 12118204.
34. Elkins MR, Robinson M, Rose BR, Harbour C, Moriarty CP, Marks GB, et al. A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis. New Engl J Med 2006, 354(3):229-240. PubMed PMID: 16421364, 10.1056/NEJMoa043900, 16421364.
35. McCoy KS, Quittner AL, Oermann CM, Gibson RL, Retsch-Bogart GZ, Montgomery AB. Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis. Am J Respir Crit Care Med 2008, 178(9):921-928. PubMed PMID: 18658109, 10.1164/rccm.200712-1804OC, 2577727, 18658109.