A novel tyrosine kinase inhibitor amn107 (nilotinib) normalizes striatal motor behaviors in a mouse model of parkinson's disease

Frontiers in Cellular Neuroscience

Volumn 8, Issue FEB, 2014, Pages

  Tanabe, Akie ^a,b   Yamamura, Yukio ^a,b   Kasahara, Jiro ^b   Morigaki, Ryoma ^a   Kaji, Ryuji ^a   Goto, Satoshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

C Abl inhibitor; Cdk5; DARPP 32; Nilotinib; Parkinson's disease

Indexed keywords

1 AMINOMETHYL 5, 6 DIHYDROXY 3 PHENYLISOCHROMAN; 1 AMINOMETHYL 5,6 DIHYDROXY 3 PHENYLISOCHROMAN; 8 CHLORO 2, 3, 4, 5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CYCLIN DEPENDENT KINASE 5; DOPAMINE 2 RECEPTOR; NILOTINIB; PROTEIN C FOS; QUINPIROLE; RACLOPRIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DENSITOMETRY; DIGITAL IMAGING; IMMUNOHISTOCHEMISTRY; INCLINED BEAM WALKING TEST; LOCOMOTION; MALE; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ROTAROD TEST; SINGLE DRUG DOSE; WESTERN BLOTTING;

EID: 84894260952     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00050     Document Type: Article

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