Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: An involvement of astrocytes

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Boku, Shuken ^a,b   Hisaoka Nakashima, Kazue ^c   Nakagawa, Shin ^b   Kato, Akiko ^b   Kajitani, Naoto ^c   Inoue, Takeshi ^b   Kusumi, Ichiro ^b   Takebayashi, Minoru ^d  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION KURE MEDICAL CENTER AND CHUGOKU CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ASTROCYTES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL PROLIFERATION; CELLS, CULTURED; DENTATE GYRUS; FIBROBLAST GROWTH FACTOR 2; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84894218081     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079371     Document Type: Article

References (38)

1. Nierenberg AA, Amsterdam JD (1990) Treatment-resistant depression: definition and treatment approaches. J Clin Psychiatry (suppl 6): 39-47. (Pubitemid 20212863)
2. Fawcett J (1994) Progress in treatment-resistant and treatment-refractory depression: we still have a long way to go. J Clin Psychiatry 24: 214-216.
3. Amsterdam JD, Hornig-Rohan M (1996) Treatment algorithms in treatment-resistant depression. PsychatrClin North Am19: 371-386. (Pubitemid 26184108)
4. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, et al. (2003) The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 289: 3095-3105. (Pubitemid 37432885)
5. Eriksson PS, Perfilieva E, Björk-Eriksson T, Alborn AM, Nordborg C, et al (1998) Neurogenesis in the adult human hippocampus. Nat Med4: 1313-1317. (Pubitemid 28512114)
6. Gage FH (2000) Mammalian neural stem cells. Science 287: 1433-1438.
7. Malberg J, Eisch AJ, Nestler EJ, Duman RS (2000) Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20: 9104-9110. (Pubitemid 32042912)
8. Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, et al. (2003) Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301: 805-809. (Pubitemid 36962615)
9. Arian RD, Meltzer LA, Roy M, Gong Y, Chen H, et al. (2007) High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science 317: 819-823. (Pubitemid 47257922)
10. Boku S, Nakagawa S, Masuda T, Nishikawa H, Kato A, et al. (2009) Glucocorticoids and lithium reciprocally regulate the proliferation of adult dentate gyrus-derived neural precursor cells through GSK-3β and β-catenin/ TCF pathway. Neuropsychopharmacology 34: 805-815.
11. Boku S, Nakagawa S, Masuda T, Nishikawa H, Kato A, et al.(2011) Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cells. Prog Neuropsychopharmacol Biol Psychiatry 35: 111-117.
12. Masuda T, Nakagawa S, Boku S, Nishikawa H, Takamura N, et al. (2012) Noradrenaline increases neural precursor cells derived from adult rat dentate gyrus through beta2 receptor. Prog Neuropsychopharmacol Biol Psychiatry 36: 44-51.
13. Pickel VM, Segal M, Bloom FE (1974) A radioautographic study of the efferent pathways of the nucleus locus coeruleus. J Comp Neurol 155: 15-42.
14. Swanson LW, Hartman BK (1975) The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-beta-hydroxylase as a marker. J Comp Neurol163: 467-505.
15. Palmer TD, Ray J, Gage FH (1995) FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol Cell Neurosci 6: 474-486.
16. Lee J, Duan W, Mattson MP (2002) Evidence that brain-derived neurotrohic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem 82: 1367-1375.
17. Fabel K, Fabel K, Tam B, kaufer D, Baiker A, et al. (2003) VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci 18: 2803-2812. (Pubitemid 37542133)
18. Chen Y, Ai Y, Slevin JR, Maley BE, Gash DM (2005) Progenitor proliferation in the adult hippocampus and substantia nigra induced by glial cell line-precursor neurotrophic factor. ExpNeurol196: 87-95. (Pubitemid 41416650)
19. Kajitani N, Hisaoka-Nakashima K, Morioka N, Okada-Tsuchioka M, Kaneko M, et al (2012) Antidepressant acts on astrocytes leading to an increase in the expression of neurotrophic/growth factors: differential regulation of FGF-2 by noradrenaline. PLoS One 7: e51197.
20. Seri B, Garcia-Vergudo JM, Collado-Morente L, McEwen BS, Alvarez-Buylla A (2004) Cell types,linage and architecture of the germinal zone in the adult dentate gyrus. J Comp Neurol478: 359-378. (Pubitemid 39305128)
21. Song H, Stevens CF, Gage FH (2002) Astroglia induce neurogenesis from neural stem cells. Nature 417: 39-44. (Pubitemid 34498810)
22. Eckenstein F, Woodward WR, Nishi R (1991) Differential localization and possible function of aFGF and bFGF in the central and peripheral nervous systems. Ann N Y AcadSci 638: 348-360.
23. Rousell J, Haddad EB, Mak JC, Webb BL, Giembycz MA, et al. (1996) Beta- Adrenoceptor-medicated down-regulation of M2 muscarinic receptors: role of cyclic adenosine 5 9-monophosphate-dependent protein kinase and protein kinase C. Mol Pharmacol 49, 629-635.
24. Nakagawa S, Kim JE, Malberg JE, Chen J, Steffen C, et al. (2002) Regulation of neurogenesis in adult mouse hippocampus by cAMP and cAMP response element-binding protein. J Neurosci 22, 3673-3682. (Pubitemid 37465772)
25. Manev ZH, Uz T, Manev R (2003) Glia as a putative target for antidepressant treatments. J Affect Disord 75: 59-64. (Pubitemid 36645020)
26. Banasar M, Duman RS (2008) Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviours. Biol Psychiatry 64: 863-870.
27. Iwata M, Shirayama Y, Ishida H, Hazama GI, Nakagome K (2011) Hippocampal astrocytes are necessary for antidepressant treatment of learned helplessness rats. Hippocampus 21: 877-884.
28. Jarosik J, Legutko B, Werner S, Unsicker K, von Bohlen Und Halbach O (2011) Roles of exogenous and endogenous FGf-2 in animal model of depression. Restor Neurol Neurosci 29: 153-165.
29. Hisaoka K, Tsuchioka M, Yano R, Maeda N, Kajitani N, et al. (2011) Tricyclic antidepressant amitriptyline activates fibroblast growth factor receptor signaling in glial cells: involvement in glial cell line-derived neurotrophic factor production. J Biol Chem 286: 21118-21128.
30. Savona C, Chambaz EM, Feige JJ (1991) Proteoheparan sulfates contribute to the binding of basic FGF to its high affinity receptors on bovine adrenocortical cells. Growth Factors 5, 273-282.
31. Taupin P, Ray J, Fischer WH, Suhr ST, Hakansson K, et al (2000) FGF-2-Responsive Neural Stem Cell Proliferation Requires CCg, a Novel Autocrine/ Paracrine Cofactor. Neuron 28, 385-397.
32. Aronica E, van Vilet EA, Hendriksen E, Troost D, Lopes da Silva FH, et al. (2001) Cystatin C, a cysteine protease inhibitor, is persistently up-regulated in neurons and glia in a rat model for mesial temporal lobe epilepsy. Eur J Neurosci14: 1485-1491. (Pubitemid 35463715)
33. Steinhoff T, Moritz E, Wollmer MA, Mojajeri MH, Kins S (2001) Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques. Neurobiol Dis 8: 647-654. (Pubitemid 32758668)
34. Arsenijevic Y, Weiss S, Schneider B, Aebischer P (2001) Insulin-like growth factor-1 is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2. J Neurosci 21: 7194-7202. (Pubitemid 32846967)
35. Allaman I, Fiumelli H, Magistretti PJ, Martin JL (2011) Fluoxetine regulates the expression of neurotrophic/growth factors and glucose metabolism in astrocytes. Psychopharmacology (Berl) 216: 75-84.
36. Mercier G, Lennon AM, Renouf B, Dessouroux A, Ramauge' M, et al. (2004) MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes. J Mol Neurosci 24: 207-216. (Pubitemid 41359148)
37. Liu Q, Li B, Zhu HY, Wang YQ, Yu J, et al (2009) Clomipramine treatment reversed the glial pathology in a chronic unpredictable stress-induced rat model of depression. Eur Neuropsychopharmacol 19: 796-805.
38. Ko HG, Lee SJ, Son H, Kaang BK (2007) Null effect of antidepressants on the astrocytes-mediated proliferation of hippocampal progenitor cells in vitro. Mol Pain 3: 16.