Insulin-like growth factor-1 is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2

Journal of Neuroscience

Volumn 21, Issue 18, 2001, Pages 7194-7202

  Arsenijevic, Yvan ^a,b   Weiss, Samuel ^c   Schneider, Bernard ^a   Aebischer, Patrick ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b HÔPITAL OPHTALMIQUE JULES GONIN   (Switzerland)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

Autocrine regulation; FGF 2; Neural stem cells; Neurogenesis; Striatum; Survival

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; EMBRYO; GROWTH REGULATION; HORMONAL REGULATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

EID: 0035884923     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-18-07194.2001     Document Type: Article

References (69)

1. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
2. BDNF enhances the differentiation but not the survival of CNS stem cell-derived neuronal precursors
3. IGF-I is a differentiation factor for postmitotic CNS stem cell-derived neuronal precursors: Distinct actions from those of BDNF
4. Role of insulin-like growth factors in embryonic and postnatal growth
5. Localization of insulin-like growth factor-1 mRNA in murine central nervous system during postnatal development
6. Development of receptors for insulin and insulin-like growth factor-I in head and brain of chick embryos: Autoradiographic localization
7. Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons
8. Growth and fate of PSA-NCAM+ precursors of the postnatal brain
9. Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I gene expression during brain development
10. Transient IGF-I gene expression during the maturation of functionally related central projection neurons
11. Cellular pattern of insulin-like growth factor-I (IGF-I) and Type I IGF receptor gene expression in early organogenesis: Comparison with IGF-II gene expression
12. Response diversity and the timing of progenitor cell maturation are regulated by developmental changes in EGFR expression in the cortex
13. Fibroblast growth factor 2 (FGF-2) promotes acquisition of epidermal growth factor (EGF) responsiveness in mouse striatal precursor cells: Identification of neural precursors responding to both EGF and FGF-2
14. Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone
15. In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain
16. Genesis of olfactory receptor neurons in vitro: Regulation of progenitor cell divisions by fibroblast growth factors
17. Murine FGFR-1 is required for early postimplantation growth and axial organization
18. The developing CNS: A scenario for the action of proinsulin, insulin and insulin-like growth factors
19. Insulin II gene expression in rat central nervous system
20. Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I
21. In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain
22. Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2
23. Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain
24. Tissue localization of Drosophila megalonaster insulin receptor during development
25. Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development
26. Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain
27. Bone morphogenetic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells
28. Myelination following transplantation of EGF-responsive neural stem cells into a myelin-deficient environment
29. Implication of insulin-like growth factors in the pathogenesis of diabetic neuropathy
30. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
31. Neuroepithelial cells from the embryonic spinal cord: Isolation, characterization, and clonal analysis
32. Expression of EGF receptor and FGF receptor isoforms during neuroepithelial stem cell differentiation
33. 125I]insulin receptor binding sites in developing and adult rat brain
34. Short communication: Transforming growth factor-beta mediates the neurotrophic effect of fibroblast growth factor-2 on midbrain dopaminergic neurons
35. Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain
36. Development of brain insulin receptors
37. Insulin-like growth factors receptors
38. BMP and FGF regulate the development of EGF-responsive neural progenitor cells
39. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
40. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf- 1) and type 1 IGF receptor (Igflr)
41. Differentiation of oligodendroglial progenitors derived from cortical multipotent cells requires extrinsic signals including activation of gp130/LIFbeta receptors
42. Hematolyphopoietic and inflammatory cytokines in neural development
43. Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways
44. Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells
45. Insulin-like growth factor-binding proteins: Functional diversity or redundancy?
46. The adult rat hippocampus contains primordial neural stem cells
47. Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an antipeptide antibody
48. FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells
49. Timing of CNS cell generation: A programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
50. Glial restricted precursors are derived from multipotent neuroepithelial stem cells
51. IGF-I increases bFGF-induced mitogenesis and upregulates FGFR-1 in rabbit vascular smooth muscle cells
52. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
53. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
54. A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
55. FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord
56. A role for the POU-III transcription factor Brn-4 in the regulation of striatal neuron precursor differentiation
57. A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor
58. Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system
59. FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor
60. Transforming growth factor-a null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma
61. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
62. Retinal stem cells in the adult mammalian eye
63. Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons
64. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells
65. Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions
66. FGFR-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
67. Self-renewing canine oligodendroglial progenitor expanded as oligospheres
68. Induction of cell proliferation by fibroblast and insulin-like growth factors in pure rat inner ear epithelial cell cultures
69. Developmental changes in progenitor cell responsiveness to cytokines