메뉴 건너뛰기




Volumn 65, Issue 6, 2013, Pages 1535-1544

Combined treatment with atypical antipsychotics and antidepressants in treatment-resistant depression: Preclinical and clinical efficacy

Author keywords

Antidepressants; Atypical antipsychotics; Augmentation; Depression; Preclinical and clinical studies

Indexed keywords

AMFEBUTAMONE; ANTIDEPRESSANT AGENT; ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; CITALOPRAM; CLOZAPINE; DESIPRAMINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; HALOPERIDOL; MILNACIPRAN; MIRTAZAPINE; OLANZAPINE; PAROXETINE; PLACEBO; QUETIAPINE; REBOXETINE; RISPERIDONE; SERTRALINE; VENLAFAXINE; VOLINANSERIN; YOHIMBINE;

EID: 84894205935     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/s1734-1140(13)71515-9     Document Type: Article
Times cited : (38)

References (50)
  • 2
    • 0030002489 scopus 로고    scopus 로고
    • Treatment algorithms in treatment-resistant depression
    • DOI 10.1016/S0193-953X(05)70293-8
    • Amsterdam JD, Hornig-Rohan M: Treatment algorithms in treatment-resistant depression. Psychiatry Clin North Am, 1996, 19, 371-386. (Pubitemid 26184108)
    • (1996) Psychiatric Clinics of North America , vol.19 , Issue.2 , pp. 371-386
    • Amsterdam, J.D.1    Hornig-Rohan, M.2
  • 3
    • 78149318681 scopus 로고    scopus 로고
    • A pooled analysis of two randomized, placebo-controlled studies, of extended release quetiapine fumarate to antidepressant therapy in patients with major depressive disorder
    • Bauer M, El-Khalili N, Datto C, Szamosi J, Eriksson H: A pooled analysis of two randomized, placebo-controlled studies, of extended release quetiapine fumarate to antidepressant therapy in patients with major depressive disorder. J Affect Disord, 2010, 127, 19-30.
    • (2010) J Affect Disord , vol.127 , pp. 19-30
    • Bauer, M.1    El-Khalili, N.2    Datto, C.3    Szamosi, J.4    Eriksson, H.5
  • 4
    • 66349134744 scopus 로고    scopus 로고
    • Extended-release quetiapine as adjunct to an antidepressant in patients with major depressive disorder: Results of a randomized, placebocontrolled, double-blind study
    • Bauer M, Pretorius HW, Constant EL, Earley WR, Szamosi J, Brecher M: Extended-release quetiapine as adjunct to an antidepressant in patients with major depressive disorder: results of a randomized, placebocontrolled, double-blind study. J Clin Psychiatry, 2009, 70, 540-549.
    • (2009) J Clin Psychiatry , vol.70 , pp. 540-549
    • Bauer, M.1    Pretorius, H.W.2    Constant, E.L.3    Earley, W.R.4    Szamosi, J.5    Brecher, M.6
  • 5
    • 66849141289 scopus 로고    scopus 로고
    • Aripiprazole augmentation in major depressive disorder: A double-blind, placebo-controlled study in patients with inadequate response to antidepressants
    • Berman RM, Fava M, Thase ME, Trivedi MH, Swanink R, McQuade RD, Carson WH et al.: Aripiprazole augmentation in major depressive disorder: a double-blind, placebo-controlled study in patients with inadequate response to antidepressants. CNS, 2009, 14, 197-206.
    • (2009) CNS , vol.14 , pp. 197-206
    • Berman, R.M.1    Fava, M.2    Thase, M.E.3    Trivedi, M.H.4    Swanink, R.5    McQuade, R.D.6    Carson, W.H.7
  • 6
    • 34347335477 scopus 로고    scopus 로고
    • The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: A multicenter, randomized, double-blind, placebo-controlled study
    • Berman RM, Marcus RN, Swanink R, McQuade RD, Carson WH, Corey-Lisle PK, Khan A: The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a multicenter, randomized, doubleblind, placebo-controlled study. J Clin Psychiatry, 2007, 68, 843-853. (Pubitemid 47015482)
    • (2007) Journal of Clinical Psychiatry , vol.68 , Issue.6 , pp. 843-853
    • Berman, R.M.1    Marcus, R.N.2    Swanink, R.3    McQuade, R.D.4    Carson, W.H.5    Corey-Lisle, P.K.6    Khan, A.7
  • 7
    • 69049097023 scopus 로고    scopus 로고
    • Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice
    • Bourin M, Chenu F, Prica C, Hascoët M: Augmentation effect of combination therapy of aripiprazole and antidepressants on forced swimming test in mice. Psychopharmacology, 2009, 206, 97-107.
    • (2009) Psychopharmacology , vol.206 , pp. 97-107
    • Bourin, M.1    Chenu, F.2    Prica, C.3    Hascoët, M.4
  • 8
    • 80053363003 scopus 로고    scopus 로고
    • Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats
    • Burda K, Czubak A, Kuoe K, Nowakowska E, Ratajczak P, Zin J: Influence of aripiprazole on the antidepressant, anxiolytic and cognitive functions of rats. Pharmacol Rep, 2011, 63, 898-907.
    • (2011) Pharmacol Rep , vol.63 , pp. 898-907
    • Burda, K.1    Czubak, A.2    Kuoe, K.3    Nowakowska, E.4    Ratajczak, P.5    Zin, J.6
  • 9
    • 49549104016 scopus 로고    scopus 로고
    • Effects of risperidone augmentation in patients with treatment-resistant depression: Results of open-label treatment followed by double-blind continuation
    • Carroll BJ: Effects of risperidone augmentation in patients with treatment-resistant depression: results of open-label treatment followed by double-blind continuation. Neuropsychopharmacology, 2008, 33, 2546-2547.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2546-2547
    • Carroll, B.J.1
  • 10
    • 33750374140 scopus 로고    scopus 로고
    • A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, fluoxetine, and venlafaxine in treatment-resistant depression
    • DOI 10.1002/da.20130
    • Corya SA, Williamson D, Sanger TM, Briggs SD, Case M, Tollefson G: A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, fluoxetine, and venlafaxine in treatment-resistant depression. Depress Anxiety, 2006, 23, 364-372. (Pubitemid 44619788)
    • (2006) Depression and Anxiety , vol.23 , Issue.6 , pp. 364-372
    • Corya, S.A.1    Williamson, D.2    Sanger, T.M.3    Briggs, S.D.4    Case, M.5    Tollefson, G.6
  • 11
    • 8744259454 scopus 로고    scopus 로고
    • Synergistic dopamine increase in the rat prefrontal cortex with the combination of quetiapine and fluvoxamine
    • DOI 10.1007/s00213-004-1880-0
    • Denys D, Klompmakers AA, Westenberg HGM: Synergistic dopamine increase in the rat prefrontal cortex with the combination of quetiapine and fluvoxamine. Psychopharmacology, 2004, 176, 195-203. (Pubitemid 39517949)
    • (2004) Psychopharmacology , vol.176 , Issue.2 , pp. 195-203
    • Denys, D.1    Klompmakers, A.A.2    Westenberg, H.G.M.3
  • 12
    • 52949119897 scopus 로고    scopus 로고
    • Risperidone, an atypical antipsychotic enhances the antidepressant-like effect of venlafaxine or fluoxetine: Possible involvement of alpha-2 adrenergic receptors
    • Dhir A, Kulkarni SK: Risperidone, an atypical antipsychotic enhances the antidepressant-like effect of venlafaxine or fluoxetine: Possible involvement of alpha-2 adrenergic receptors. Neurosci Lett, 2008, 445, 83-88.
    • (2008) Neurosci Lett , vol.445 , pp. 83-88
    • Dhir, A.1    Kulkarni, S.K.2
  • 13
    • 77956440952 scopus 로고    scopus 로고
    • Extended-release quetiapine fumarate (quetiapine xr) as adjunctive therapy in major depressive disorder (mdd) in patients with an inadequate response to ongoing antidepressant treatment: A multicentre, randomized, double-blind, placebocontrolled study
    • El-Khalili N, Joyce M, Atkinson S, Buynaki RJ, Datto C, Lindgren P, Eriksson H: Extended-release quetiapine fumarate (quetiapine XR) as adjunctive therapy in major depressive disorder (MDD) in patients with an inadequate response to ongoing antidepressant treatment: a multicentre, randomized, double-blind, placebocontrolled study. Int J Neuropsychopharmacol, 2010, 13, 917-932.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 917-932
    • El-Khalili, N.1    Joyce, M.2    Atkinson, S.3    Buynaki, R.J.4    Datto, C.5    Lindgren, P.6    Eriksson, H.7
  • 14
    • 33645097092 scopus 로고    scopus 로고
    • Augmentation by citalopram of risperidone-induced monoamine release in rat prefrontal cortex
    • Huang M, Ichiwara J, Li Z, Dai J, Meltzer HY: Augmentation by citalopram of risperidone-induced monoamine release in rat prefrontal cortex. Psychopharmacology, 2006, 185, 274-281.
    • (2006) Psychopharmacology , vol.185 , pp. 274-281
    • Huang, M.1    Ichiwara, J.2    Li, Z.3    Dai, J.4    Meltzer, H.Y.5
  • 15
    • 0031863323 scopus 로고    scopus 로고
    • Effect of antipsychotic drugs on extracellular serotonin levels in rat medial prefrontal cortex and nucleus accumbens
    • DOI 10.1016/S0014-2999(98)00308-2, PII S0014299998003082
    • Ichikawa J, Kuroki T, Dai J, Meltzer HY: Effect of antipsychotic drugs on extracellular serotonin levels in rat medial prefrontal cortex and nucleus accumbens. Eur J Pharmacol, 1998, 351, 163-171. (Pubitemid 28312927)
    • (1998) European Journal of Pharmacology , vol.351 , Issue.2 , pp. 163-171
    • Ichikawa, J.1    Kuroki, T.2    Dai, J.3    Meltzer, H.Y.4
  • 17
    • 56649111416 scopus 로고    scopus 로고
    • Potentiation of the antidepressant-like effect of fluoxetine by aripiprazole in mice tail suspension test
    • Kamei J, Miyata S, Sunohara T, Kamei A, Shimada M, Ohsawa M: Potentiation of the antidepressant-like effect of fluoxetine by aripiprazole in mice tail suspension test. J Pharmacol Sci, 2008, 108, 381-384.
    • (2008) J Pharmacol Sci , vol.108 , pp. 381-384
    • Kamei, J.1    Miyata, S.2    Sunohara, T.3    Kamei, A.4    Shimada, M.5    Ohsawa, M.6
  • 18
    • 84894127557 scopus 로고    scopus 로고
    • The effect of risperidone on the fluoxetine-induced changes in extracellular dopamine serotonin and noradrenaline in the rat frontal cortex
    • Kamiñska K, Goembiowska K, Rogó Z: The effect of risperidone on the fluoxetine-induced changes in extracellular dopamine, serotonin and noradrenaline in the rat frontal cortex. Pharmacol Rep, 2013, 65, 1144-1151.
    • (2013) Pharmacol Rep , vol.65 , pp. 1144-1151
    • Kamiñska, K.1    Goembiowska, K.2    Rogó, Z.3
  • 19
    • 84886314936 scopus 로고    scopus 로고
    • Augmentation treatments with second-generation antipsychotics to antidepressants in treatment-resistant depression
    • Kato M, Chang C-M: Augmentation treatments with second-generation antipsychotics to antidepressants in treatment-resistant depression. CNS Drugs, 2013, 27, Suppl 1, S11-S19.
    • (2013) CNS Drugs , vol.27 , Issue.SUPPL. 1
    • Kato, M.1    Chang, C.-M.2
  • 20
    • 57749198414 scopus 로고    scopus 로고
    • A randomized, placebocontrolled trial of risperidone augmentation for patients with difficult-to-treat unipolar, non-psychotic major depression
    • Keitner GI, Garlow SJ, Ryan CE, Ninan PT, Solomon DA, Nemeroff CB, Keller MB: A randomized, placebocontrolled trial of risperidone augmentation for patients with difficult-to-treat unipolar, non-psychotic major depression. J Psychiatry Res, 2009, 43, 205-214.
    • (2009) J Psychiatry Res , vol.43 , pp. 205-214
    • Keitner, G.I.1    Garlow, S.J.2    Ryan, C.E.3    Ninan, P.T.4    Solomon, D.A.5    Nemeroff, C.B.6    Keller, M.B.7
  • 21
    • 0029023002 scopus 로고
    • 7-(4-[4-(2,3-Dichlorophenyl)-piperazinyl]butyloxy)-3,4-dihydro-2(1H) -quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity
    • Kikuchi T, Tottori K, UwahodoY, Hirose T, Miwa T, Oshiro Y, Morita S: 7-(4-[4-(2,3-Dichlorophenyl)-piperazinyl]butyloxy)-3,4-dihydro-2(1H) -quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity. J Pharmacol Exp Ther, 1995, 274, 329-336.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 329-336
    • Kikuchi, T.1    Tottori, K.2    UwahodoY Hirose, T.3    Miwa, T.4    Oshiro, Y.5    Morita, S.6
  • 22
    • 0000587671 scopus 로고
    • The serotonin hypothesis of major depression
    • Eds. Bloom FE, Kupfer DJ, Raven Press Ltd., New York
    • Maes M, Meltzer HY: The serotonin hypothesis of major depression. In: Psychopharmacology: The Fourth Generation of Progress. Eds. Bloom FE, Kupfer DJ, Raven Press Ltd., New York, 1995, 933-944.
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 933-944
    • Maes, M.1    Meltzer, H.Y.2
  • 24
    • 84856391332 scopus 로고    scopus 로고
    • Augmentation of escitalopram, but not citalopram or r-citalopram, of the effects of low-dose risperidone: Behavioral, biochemical, and electeophysiological evidence
    • Marcus MM, Jardemark K, Malmerfelt A, Gertow J, Konradsson-Geuken Ä, Svensson TH: Augmentation of escitalopram, but not citalopram or R-citalopram, of the effects of low-dose risperidone: behavioral, biochemical, and electeophysiological evidence. Synapse, 2012, 66, 277-290.
    • (2012) Synapse , vol.66 , pp. 277-290
    • Marcus, M.M.1    Jardemark, K.2    Malmerfelt, A.3    Gertow, J.4    Konradsson-Geuken, Ä.5    Svensson, T.H.6
  • 25
    • 40949089056 scopus 로고    scopus 로고
    • The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: A second multicenter, randomized, double-blind, placebo-controlled study
    • DOI 10.1097/JCP.0b013e31816774f9, PII 0000471420080400000005
    • Marcus RN, McQuade RD, Carson WH, Hennicken D, Fava M, Simon JS, Trivedi MH et al.: The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study. J Clin Psychopharmacol, 2008, 28, 156-165. (Pubitemid 351417120)
    • (2008) Journal of Clinical Psychopharmacology , vol.28 , Issue.2 , pp. 156-165
    • Marcus, R.N.1    McQuade, R.D.2    Carson, W.H.3    Hennicken, D.4    Fava, M.5    Simon, J.S.6    Trivedi, M.H.7    Thase, M.E.8    Berman, R.M.9
  • 26
    • 36049015484 scopus 로고    scopus 로고
    • Quetiapine adjunct to selective serotonin reuptake inhibitors or venlafaxine in patients with major depression, comorbid anxiety, and residual depressive symptoms: A randomized, placebo-controlled pilot study
    • DOI 10.1002/da.20275
    • McIntyre A, Gendron A: Quetiapine adjunct to selective serotonin reuptake inhibitors or venlafaxine in patients with major depression, comorbid anxiety, and residual depressive symptoms: a randomized, placebo-controlled pilot study. Depress Anxiety, 2007, 24, 487-494. (Pubitemid 350086262)
    • (2007) Depression and Anxiety , vol.24 , Issue.7 , pp. 487-494
    • McIntyre, A.1    Gendron, A.2    McIntyre, A.3
  • 27
    • 0026091799 scopus 로고
    • The mechanism of action of novel antipsychotic drugs
    • Meltzer HY: The mechanism of action of novel antipsychotic drugs. Schizophr Bull, 1991, 17, 263-287.
    • (1991) Schizophr Bull , vol.17 , pp. 263-287
    • Meltzer, H.Y.1
  • 28
    • 0345131659 scopus 로고    scopus 로고
    • Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo.
    • Millan MJ, Dekeyne A, Gobert A: Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo. Neuropharmacology, 1998, 37, 953-955.
    • (1998) Neuropharmacology , vol.37 , pp. 953-955
    • Millan, M.J.1    Dekeyne, A.2    Gobert, A.3
  • 29
    • 2442521392 scopus 로고    scopus 로고
    • Mirtazapine increases dopamine release in prefrontal cortex by 5-ht1a receptor activation
    • Nakayama K, Sakurai T, Katsu H: Mirtazapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation. Brain Res Bull, 2004, 63, 237-231.
    • (2004) Brain Res Bull , vol.63 , pp. 237-231
    • Nakayama, K.1    Sakurai, T.2    Katsu, H.3
  • 30
    • 0028169161 scopus 로고
    • Actions of 5-hydroxytryptamine on ventral tegmental area neurons of the rat in vitro
    • Pessia M, Jiang ZG, North RA, Johnson SW: Actions of 5-hydroxytryptamine on ventral tegmental area neurons of the rat in vitro. Brain Res, 1994, 654, 324-330.
    • (1994) Brain Res , vol.654 , pp. 324-330
    • Pessia, M.1    Jiang, Z.G.2    North, R.A.3    Johnson, S.W.4
  • 32
    • 49649096422 scopus 로고    scopus 로고
    • Efficacy of risperidone augmentation to antidepressants in the management of suicidality in major depressive disorder: A randomized, double-blind, placebo-controlled pilot study
    • Reeves H, Batra S, May RS, Zhang R, Dahl DC, Li X: Efficacy of risperidone augmentation to antidepressants in the management of suicidality in major depressive disorder: a randomized, double-blind, placebo-controlled pilot study. J Clin Psychiatry, 2008, 69, 1228-1336.
    • (2008) J Clin Psychiatry , vol.69 , pp. 1228-1336
    • Reeves, H.1    Batra, S.2    May, R.S.3    Zhang, R.4    Dahl, D.C.5    Li, X.6
  • 33
    • 0034711425 scopus 로고    scopus 로고
    • Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds
    • Richelson E, Souder T: Binding of antipsychotic drugs to human brain receptors focus on newer generation compounds. Life Sci, 2000, 68, 29-39.
    • (2000) Life Sci , vol.68 , pp. 29-39
    • Richelson, E.1    Souder, T.2
  • 34
    • 79551493931 scopus 로고    scopus 로고
    • Effects of co-treatment with mirtazapine and low doses of risperidone on the immobility time in the forced swimming test in mice
    • Rogó Z: Effects of co-treatment with mirtazapine and low doses of risperidone on the immobility time in the forced swimming test in mice. Pharmacol Rep, 2010, 62, 1191-1196.
    • (2010) Pharmacol Rep , vol.62 , pp. 1191-1196
    • Rogó, Z.1
  • 35
    • 84857495768 scopus 로고    scopus 로고
    • Enhancement of the antiimmobility action of antidepressants by risperidone in the forced swimming test in mice
    • Rogó Z, Kabziñski M: Enhancement of the antiimmobility action of antidepressants by risperidone in the forced swimming test in mice. Pharmacol Rep, 2011, 63, 1533-1538.
    • (2011) Pharmacol Rep , vol.63 , pp. 1533-1538
    • Rogó, Z.1    Kabziñski, M.2
  • 36
    • 84873709663 scopus 로고    scopus 로고
    • Effect of co-treatment with fluoxetine or mirtazapine and risperidone on the active behaviors and plasma corticosterone concentration in rats subjected to the forced swim test
    • Rogó Z, Kabziñski M, Sadaj W, Rachwalska P, Gdek-Michalska A: Effect of co-treatment with fluoxetine or mirtazapine and risperidone on the active behaviors and plasma corticosterone concentration in rats subjected to the forced swim test. Pharmacol Rep, 2012, 64, 1391-1399.
    • (2012) Pharmacol Rep , vol.64 , pp. 1391-1399
    • Rogó, Z.1    Kabziñski, M.2    Sadaj, W.3    Rachwalska, P.4    Gdek-Michalska, A.5
  • 37
    • 0002735385 scopus 로고
    • Recent studies on norepinephrine systems in mood disorders
    • Eds. Bloom FE, Kupfer DJ, Raven Press Ltd., New York
    • Schatzberg AF, Schildkraut J: Recent studies on norepinephrine systems in mood disorders. In: Psychopharmacology: The Fourth Generation of Progress. Eds. Bloom FE, Kupfer DJ, Raven Press Ltd., New York, 1995, 911-920.
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 911-920
    • Schatzberg, A.F.1    Schildkraut, J.2
  • 38
    • 79952219529 scopus 로고    scopus 로고
    • Effect of s-citalopram, citalopram, and r-citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, n-methyl-d-aspartate receptor-mediated transmission in the medial prefrontal cortex and cognitive function in the rat
    • Schilstrõm B, Konradsson-Geuken A, Ivanov V, Gertow J, Feltmann K, Marcus MM, Jardemark K, Svensson TH: Effect of S-citalopram, citalopram, and R-citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, N-methyl-D-aspartate receptor-mediated transmission in the medial prefrontal cortex and cognitive function in the rat. Synapse, 2011, 65, 357-367.
    • (2011) Synapse , vol.65 , pp. 357-367
    • Schilstrõm, B.1    Konradsson-Geuken, A.2    Ivanov, V.3    Gertow, J.4    Feltmann, K.5    Marcus, M.M.6    Jardemark, K.7    Svensson, T.H.8
  • 40
    • 0033063496 scopus 로고    scopus 로고
    • Treatment options for refractory depression
    • Shelton RC: Treatment options for refractory depression. J Clin Psychiatry, 1999, 60, Suppl 4, 57-61.
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 4 , pp. 57-61
    • Shelton, R.C.1
  • 41
    • 40449093482 scopus 로고    scopus 로고
    • Augmentation of antidepressants with atypical antipsychotics for treatment-resistant major depressive disorder
    • DOI 10.1111/j.1600-0447.2007.01130.x
    • Shelton RC, Papakostas GI: Augmentation of antidepressants with atypical antypsychotics for treatment-resistant major depressive disorder. Acta Psychiatr Scand, 2008, 117, 253-259. (Pubitemid 351350599)
    • (2008) Acta Psychiatrica Scandinavica , vol.117 , Issue.4 , pp. 253-259
    • Shelton, R.C.1    Papakostas, G.I.2
  • 44
    • 79953823769 scopus 로고    scopus 로고
    • Efficacy and safety of adjunctive aripiprazole in major depressive disorder in older patients: A pooled subpopulation analysis
    • Steffens DC, Nelson JC, Eudicone JM, Andersson C, Yang H, Tran QV, Forbes RA et al.: Efficacy and safety of adjunctive aripiprazole in major depressive disorder in older patients: a pooled subpopulation analysis. Int J Geriatr Psychiatry, 2011, 26, 564-572.
    • (2011) Int J Geriatr Psychiatry , vol.26 , pp. 564-572
    • Steffens, D.C.1    Nelson, J.C.2    Eudicone, J.M.3    Andersson, C.4    Yang, H.5    Tran, Q.V.6    Forbes, R.A.7
  • 45
    • 33847681848 scopus 로고    scopus 로고
    • A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, and fluoxetine in treatment-resistant major depressive disorder
    • Thase ME, Corya SA, Osuntokun O, Case M, Henley DB, Sanger TM, Watson SB, Dubé S: A randomized, double-blind comparison olanzapine/fluoxetine combination, olanzapine, and fluoxetine in treatment-resistant major depressive disorder. J Clin Psychiatry, 2007, 68, 224-236. (Pubitemid 46362643)
    • (2007) Journal of Clinical Psychiatry , vol.68 , Issue.2 , pp. 224-236
    • Thase, M.E.1    Corya, S.A.2    Osuntokun, O.3    Case, M.4    Henley, D.B.5    Sanger, T.M.6    Watson, S.B.7    Dube, S.8
  • 47
    • 0001217222 scopus 로고
    • Dopaminergic mechanism in depression and mania
    • Eds. Bloom FE, Kupfer DJ, Raven Press Ltd., New York
    • Willner P: Dopaminergic mechanism in depression and mania. In: Psychopharmacology: The Fourth Generation of Progress. Eds. Bloom FE, Kupfer DJ, Raven Press Ltd., New York, 1995, 921-931.
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 921-931
    • Willner, P.1
  • 48
    • 84875468867 scopus 로고    scopus 로고
    • Augmentation with atypical antipsychotics for depression: A review of evidence-based support from the medical literature
    • Wright BM, Eiland III EH, Lorenz R: Augmentation with atypical antipsychotics for depression: A review of evidence-based support from the medical literature. Pharmacotherapy, 2013, 33, 344-359.
    • (2013) Pharmacotherapy , vol.33 , pp. 344-359
    • Wright, B.M.1    Eiland III, E.H.2    Lorenz, R.3
  • 49
    • 84871568579 scopus 로고    scopus 로고
    • Antidepressant and antipsychotic activity of new quinaline-and isoquinaline-sulfonamide analogs of aripiprazole targeting serotonin 5-ht1a/5-ht2a/5-ht7 and dopamine d2/d3 receptors
    • Zajdel P, Marciniec K, Maoelankiewicz A, Grychowska K, Sataa G, Duszyñska B, Lenda T et al.: Antidepressant and antipsychotic activity of new quinaline-and isoquinaline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT1A/5-HT2A/5-HT7 and dopamine D2/D3 receptors. Eur J Med Chem, 2013, 60, 42-50.
    • (2013) Eur J Med Chem , vol.60 , pp. 42-50
    • Zajdel, P.1    Marciniec, K.2    Maoelankiewicz, A.3    Grychowska, K.4    Sataa, G.5    Duszyñska, B.6    Lenda, T.7
  • 50
    • 0034285086 scopus 로고    scopus 로고
    • Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex
    • DOI 10.1016/S0893-133X(00)00119-6, PII S0893133X00001196
    • Zhang W, Perry KW, Wong DT, Potts BD, Bao JQ, Tollefson GD, Bymaster FP: Synergistic effect of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex. Neuropsychopharmacology, 2000, 23, 250-262. (Pubitemid 30609659)
    • (2000) Neuropsychopharmacology , vol.23 , Issue.3 , pp. 250-262
    • Zhang, W.1    Perry, K.W.2    Wong, D.T.3    Potts, B.D.4    Bao, J.5    Tollefson, G.D.6    Bymaster, F.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.