Nutraceutical intervention improves older adults' cognitive functioning

Rejuvenation Research

Volumn 17, Issue 1, 2014, Pages 27-32

  Small, Brent J ^a   Rawson, Kerri S ^b   Martin, Christina ^a   Eisel, Sarah L ^a   Sanberg, Cyndy D ^c   McEvoy, Cathy L ^a   Sanberg, Paul R ^d   Shytle, R Douglas ^d   Tan, Jun ^d   Bickford, Paula C ^d,e  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Natura Therapeutics Inc   (United States)

^d UNIVERSITY OF SOUTH FLORIDA   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AGED, 80 AND OVER; COGNITION; DIETARY SUPPLEMENTS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; PATIENT COMPLIANCE; PLACEBOS;

EID: 84894132617     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2013.1477     Document Type: Article

References (33)

1. Wagster MV, King JW, Resnick SM, Rapp PR. The 87%. J Gerontol A Biol Sci Med Sci 2012;67:739-740.
2. Carlson MC, Erickson KI, Kramer AF, Voss MW, Bolea N, Mielke M, McGill S, Rebok GW, Seeman T, Fried LP. Evidence for neurocognitive plasticity in at-risk older adults: The Experience Corps Program. J Gerontol A Biol Sci Med Sci 2009;64A:1275-1282.
3. Kramer AF, Hahn S, Cohen NJ, Banich MT, McAuley E, Harrison CR, Chason J, Vakil E, Bardell L, Boileau RA, Colcombe A. Ageing, fitness and neurocognitive function. Nature 1999;400:418-419.
4. Ball KK, Berch DB, Helmers KF, Jobe JB, Leveck MD, Marsiske M, Morris JN, Rebok GW, Smith DM, Tennstedt SL, Unverzagt FW, Willis SL, for the ACTIVE Study Group. Effect of cognitive training interventions with older adults: A randomized controlled trial. JAMA 2002;288:2271-2281.
5. Edwards JD, Wadley VG, Myers R, Roenker DL, Cissell GM, Ball KK. Transfer of a speed of processing intervention to near and far cognitive functions. Gerontology 2002;48: 329-340.
6. Hertzog C, Kramer AF, Wilson RS, Lindenberger U. Enrichment effects on adult cognitive development: Can the functional capacity of older adults be preserved and enhanced? Psycholog Sci Publ Interest 2008;9:1-65.
7. Small BJ, Dixon RA, McArdle JJ, Grimm KJ. Do changes in lifestyle engagement moderate cognitive decline in normal aging? Evidence from the Victoria Longitudinal Study. Neuropsychology 2012;26:144-155.
8. Shineman DW, Salthouse TA, Launer LJ, et al. Therapeutics for cognitive aging. Ann NY Acad Sci 2010;1191(S1):1-10.
9. Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS. Associations of vegetable and fruit consumption with agerelated cognitive change. Neurology 2006;67:1370-1376.
10. Craft S, Foster TC, Landfield PW, Maier SF, Resnick SM, Yaffe K. Session III: Mechanisms of age-related cognitive change and targets for intervention: Inflammatory, oxidative, and metabolic processes. J Gerontol A Biol Sci Med Sci 2012;67:754-759.
11. Dai Q, Borenstein AR, Wu Y, Jackson JC, Larson EB. Fruit and vegetable juices and Alzheimer's disease: The KAME project. Am J Med 2006;119:751-759.
12. Shukitt-Hale B. Blueberries and neuronal aging. Gerontology 2012;58:518-523.
13. Devore EE, Kang JH, Breteler MM, Grodstein F. Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol 2012;72:135-143.
14. Rowland IR, Wiseman H, Sanders TA, Adlercreutz H, Bowey EA. Interindividual variation in metabolism of soy isoflavones and lignans: Influence of habitual diet on equol production by the gut microflora. Nutr Cancer 2000;36:27-32.
15. Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, Bickford PC. Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J Neurosci 1998;18:8047-8055.
16. Milgram NW, Head E, Zicker SC, Ikeda-Douglas CJ, Murphey H, Muggenburg B, Siwak C, Tapp D, Cotman CW. Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: A two-year longitudinal study. Neurobiol Aging 2005;26:77-90.
17. Head E, Murphey HL, Dowling AL, McCarty KL, Bethel SR, Nitz JA, Pleiss M, Vanrooyen J, Grossheim M, Smiley JR, Murphy MP, Beckett TL, Pagani D, Bresch F, Hendrix C. A combination cocktail improves spatial attention in a canine model of human aging and Alzheimer's disease. J Alzheimers Dis 2012;32:1029-1042.
18. Folstein M, Folstein S, McHugh P. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
19. Ware JE, Kosinsiki M, Keller SD. A 12-item short-form health survey: Construction of scales and preliminary tests of reliability and validity. Med Care 1996;34:220-233.
20. Radloff LS. The CES-D scale: A self-report depression scale for research in the general population. Appl Psycholog Measurement 1977;1:385-401.
21. Lezak MD, Howieson DB, Loring DW. Neuropsychological Assessment, 4th ed. Oxford University Press, New York, 2004.
22. Ekstrom RB, French JW, Harman HH, Dermen D. Manual for kit of factor referenced cognitive tests. Educational Testing Service, Princeton, NJ, 1976.
23. Reitan R, Wolfson D. The Halstead-Reitan neuropsychological test battery. Neuropsychology Press, Tuscon, AZ, 1985.
24. Wechsler D. WAIS-R manual: Weschler adult intelligence scale-revised. Psychological Corporation, 1981.
25. Benton AL, S. HKd. Multilingual aphasia examination: Manual of instructions. AJA, Iowa City, 1989.
26. Spreen O, Strauss E. A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary. Oxford University Press, USA, 1998.
27. Cohen J. Statistical Power Analysis for the Behavioral Sciences, 2nd ed. Lawrence Erlbaum Associates, Hillsdale, NJ, 1988.
28. Craik FIM, Salthouse TA, eds. The Handbook of Aging and Cognition. Psychology Press, New York, 2007.
29. Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, Joseph JA. Blueberry supplementation improves memory in older adults. J Agric Food Chem 2010;58:3996-4000.
30. Krikorian R, Boespflug EL, Fleck DE, Stein AL, Wightman JD, Shidler MD, Sadat-Hossieny S. Concord grape juice supplementation and neurocognitive function in human aging. J Agric Food Chem 2012;60:5736-5742.
31. Lindenberger U, Mayr U, Kliegl R. Speed and intelligence in old age. Psychol Aging 1993;8:207-220.
32. Salthouse TA. The processing speed theory of adult age differences in cognition. Psycholog Rev 1996;103:403-428.
33. Chapman SB, Cotman CW, Fillit HM, Gallagher M, van Dyck CH. Clinical trials: New opportunities. J Gerontol A Biol Sci Med Sci 2012;67:773-780.