Central nervous system involvement in hemophagocytic lymphohistiocytosis: A single-center experience

Pediatric Neurology

Volumn 50, Issue 3, 2014, Pages 233-237

  Jovanovic, Ankica ^a   Kuzmanovic, Milos ^a   Kravljanac, Ruzica ^a   Micic, Dragan ^a   Jovic, Milena ^a   Gazikalovic, Slobodan ^a   Pasic, Srdjan ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

central nervous system; children; hemophagocytic lymphohistiocytosis; outcome

Indexed keywords

CENTRAL NERVOUS SYSTEM; CHILDREN; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; OUTCOME;

ADOLESCENT; BRAIN; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MAGNETIC RESONANCE IMAGING; MALE; PROGNOSIS; ROC CURVE; SURVIVAL ANALYSIS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84894086480     PISSN: 08878994     EISSN: 18735150     Source Type: Journal    
DOI: 10.1016/j.pediatrneurol.2013.10.014     Document Type: Article

References (23)

1. S. Gupta, and S. Weitzman Primary and secondary lymphohistiocytosis: clinical features, pathogenesis and therapy Expert Rev Clin Immunol 6 2010 137 154
2. A.H. Filipovich The expanding spectrum of hemophagocytic lymphohistiocytosis Curr Opin Allergy Clin Immunol 11 2011 512 516
3. K. Lehmberg, and S. Ehl Diagnostic evaluation of patients with suspected hemophagocytic lymphohistiocytosis Br J Haematol 160 2013 275 287
4. S.F. Bode, K. Lehmberg, and A. Maul-Pavicic et al. Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Arthritis Res Ther 14 2012 213 232
5. A.H. Filipovich Hemophagocytic lymphohistiocytosis and related disorders Curr Opin Allergy Clin Immunol 6 2006 410 415
6. E. Haddad, M.L. Sulis, and N. Jabado et al. Frequency and severity of central nervous system lesions in hemophagocytic lymphohistiocytosis Blood 89 1997 794 800
7. G.E. Janka Familial hemophagocytic lymphohistiocytosis Eur J Pediatr 140 1983 221 230
8. M. Arico, G. Janka, A. Fischer FHL Study Group of the Histiocyte Society Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry Leukemia 10 1996 197 203
9. J.I. Henter, and I. Nennesmo Neuropathologic findings and neurologic symptoms in twenty-three children with hemophagocytic lymphohistiocytosis J Pediatr 130 1997 358 365
10. J.I. Henter, A.C. Horne, and M. Arico et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis Pediatr Blood Cancer 48 2007 124 131
11. A. Horne, H. Trottestam, and M. Arico et al. Frequency and spectrum of central nervous system involvement in 193 children with hemophagocytic lymphohistiocytosis Br J Haematol 140 2008 327 335
12. J.I. Henter, G. Elinder, and O. Soder et al. Hypercytokinemia in familial hemophagocytic lymphohistiocytosis Blood 78 1991 2918 2922
13. J.I. Henter, A. Samuelsson-Horne, M. Arico Histiocyte Society Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation Blood 100 2002 2367 2373
14. S. Yang, Z. Li, and J. Chenguang et al. Frequency and development of CNS involvement in Chinese children with hemophagocytic lymphohistiocytosis Pediatr Blood Cancer 54 2010 408 415
15. W.J. Hirst, D.M. Layton, and S. Singh et al. Haemophagocytic lymphohistiocytosis: experience at two U.K. centers Br J Haematol 88 1994 731 739
16. K. Deiva, N. Mahlaoui, and F. Beaudonnet et al. CNS involvement at the onset of primary hemophagocytic lymphohistiocytosis Neurology 78 2012 1150 1156
17. H.W. Goo, and Y.C. Weon A spectrum of neuroradiological findings in children with hemophagocytic lymphohistiocytosis Pediatr Radiol 37 2007 1110 1117
18. M.M. Puliyel, W. Rose, S. Kumar, P.D. Moses, and S. Gibikote Prolonged neurologic course of familial hemophagocytic lymphohistiocytosis Pediatr Neurol 41 2009 207 210
19. L. Rooms, N. Fitzgerald, and K.L. McClain Hemophagocytic lymphohistiocytosis masquerading as child abuse: presentation of three cases and review of central nervous system findings in hemophagocytic lymphohistiocytosis Pediatrics 111 2003 e636 e640
20. J. Shinoda, S. Murase, K. Takenaka, and N. Sakai Isolated central nervous system hemophagocytic lymphohistiocytosis: case report Neurosurgery 56 2005 187
21. I. Rego, M. Severino, and C. Micalizzi et al. Neuroradiologic findings and follow-up with magnetic resonance imaging of the genetic forms of hemophagocytic lymphohistiocytosis with CNS involvement Pediatr Blood Cancer 58 2012 810 814
22. K. Akiyoshi, Y. Hamada, H. Yamada, M. Kojo, and T. Izumi Acute necrotizing encephalopathy associated with hemophagocytic syndrome Pediatr Neurol 34 2006 315 318
23. M. Mizuguchi, J. Abe, and K. Mikaichi Acute necrotizing encephalopathy of childhood: a new syndrome presenting with multifocal, symmetric brain lesions J Neurosurg Psychiatry 58 1995 555 561