Role of Cytokine Hemoadsorption in Cardiopulmonary Bypass-Induced Ventricular Dysfunction in a Porcine Model

Journal of Extra-Corporeal Technology

Volumn 45, Issue 4, 2013, Pages 220-227

  Vocelka, Craig R ^a   Jones, Krystal M ^a   Mikhova, Krasimira M ^a   Ebisu, Ryan M ^a   Shar, Ashley ^a   Kellum, John A ^b   Verrier, Edward D ^a   Rabkin, David G ^a  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

cardiopulmonary bypass; CPB; cytokines; filter; LV function

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FILTER; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; DISEASE MODEL; HEART CATHETER; HEART INDEX; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART PRELOAD; HEART STROKE VOLUME; HEMADSORPTION; NONHUMAN; PORCINE MODEL; PREDICTIVE VALUE; PROTEIN EXPRESSION; TISSUE LEVEL; WATER CONTENT; YORKSHIRE PIG;

ANIMALS; CARDIOPULMONARY BYPASS; CYTOKINES; DISEASE MODELS, ANIMAL; HEMOFILTRATION; MALE; MODELS, ANIMAL; SWINE; VENTRICULAR DYSFUNCTION; VENTRICULAR FUNCTION, LEFT;

EID: 84894062727     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Taylor KM. SIRS-The systemic inflammatory response syndrome after cardiac operations. Ann Thorac Surg. 1996;61:1607-8.
2. Kirklin JK. Prospects for understanding and eliminating the deleterious effects of cardiopulmonary bypass. Ann Thorac Surg. 1991; 51:529-31.
3. Aybek T, Kahn MF, Dogan S, et al. Cardiopulmonary bypass impairs left ventricular function determined by conductance catheter measurement. Thorac Cardiovasc Surg. 2003;51:301-5.
4. Tio RA, Nieken J, de Vries EGE, et al. Negative inotropic effects of recombinant interleukin 2 in patients without left ventricular dysfunction. Eur J Heart Fail. 2000;2:167-73.
5. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science. 1992;257:387-9.
6. Birks EJ, Burton PB, Owen W, et al. Elevated tumor necrosis factoralpha and interleukin-6 in myocardium and serum of malfunctioning donor hearts. Circulation. 2000;102(suppl III):III-352-8.
7. Hennein HA, Ebba J, Rodriguez JL, et al. Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization. J Thorac Cardiovasc Surg. 1994;108:626-35.
8. Song M, Winchester J, Albright RL, Capponi VJ, Choquette MD, Kellum JA. Cytokine removal with a novel adsorbent polymer. Blood Purif. 2004;22:428-34.
9. Kellum JA, Song M, Venkataraman R. Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-kb DNA binding, and improves short-term survival in lethal endotoxemia. Crit Care Med. 2004;32:801-5.
10. Kellum JA, Venkataraman R, Powner D, Elder M, Hergenroeder G, Carter M. Feasibility study of cytokine removal by hemoadsorption in brain-dead humans. Crit Care Med. 2008;36:268-72.
11. Mikhova KM, Don CW, Laflamme M, et al. Effect of cytokine hemoadsorption on brain death-induced ventricular dysfunction in a porcine model. J Thorac Cardiovasc Surg. 2013;145:215-23.
12. Wei C-L, Valvano JW, Feldman MD, Nahrendorf M, Peshock R, Pearce JA. Volume catheter parallel conductance varies between endsystole and end-diastole. IEE Trans Biomed Eng. 2007;54:1480-9.
13. Glower DD, Spratt JA, Snow ND, et al. Linearity of the Frank- Starling relationship in the intact heart: The concept of preload recruitable stroke work. Circulation. 1985;71:994-1009.
14. Weiss JL, Frederiksen JW, Weisfeldt ML. Hemodynamic determinants of the time-course of fall in canine left ventricular pressure. J Clin Invest. 1976;58:751-60.
15. Kellum JA, Levin N, Bouman C, Lameire N. Developing a classification system for acute renal failure. Curr Opin Crit Care. 2002; 8:509-14.
16. Ashraf S, Butler J, Tian Y, et al. Inflammatory mediators in adults undergoing cardiopulmonary bypass: Comparison of centrifugal and roller pumps. Ann Thorac Surg. 1998;65:480-4.
17. Baufreton C, Intrator L, Jansen PG, et al. Inflammatory response to cardiopulmonary bypass using roller or centrifugal pumps. Ann Thorac Surg. 1999;67:972-7.
18. Richter JA, Meisner H, Tassani P, Barankay A, Dietrich W, Braun SL. Drew-Anderson technique attenuates systemic inflammatory response syndrome and improves respiratory function after coronary artery bypass grafting. Ann Thorac Surg. 2000;69:77-83.
19. Gu YJ, van Oeveren W, Akkerman C, Boonstra PW, Huyzen RJ, Wildevuur CRH. Heparin-coated circuits reduce the inflammatory response to cardiopulmonary bypass. Ann Thorac Surg. 1993;55:917-22.
20. Defraigne J-O, Pincemail J, Larbuisson R, Blaffart F, Limet R. Cytokine release and neutrophil activation are not prevented by heparincoated circuits and aprotinin administration. Ann Thorac Surg. 2000; 69:1084-91.
21. Kleinman LH, Wechsler AS. Pressure-flow characteristics of the coronary collateral circulation during cardiopulmonary bypass. Effects of ventricular fibrillation. Circulation. 1978;58:233-9.
22. Kleinman LH, Yarbrough JW, Symmonds JB, Wechsler AS. Pressureflow characteristics of the coronary collateral circulation during cardiopulmonary bypass, Effects of hemodilution. J Thorac Cardiovasc Surg. 1978;75:17-27.