Berberine attenuates high glucose-induced proliferation and extracellular matrix accumulation in mesangial cells: Involvement of suppression of cell cycle progression and NF-κB/AP-1 pathways

Molecular and Cellular Endocrinology

Volumn 384, Issue 1-2, 2014, Pages 109-116

  Lan, Tian ^a,b   Wu, Teng ^b   Chen, Cheng ^a   Chen, Xiaolan ^b   Hao, Jie ^a   Huang, Junying ^a   Wang, Lijing ^b   Huang, Heqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

AP 1; Berberine; Cell cycle; High glucose; Mesangial cells; NF B

Indexed keywords

BERBERINE; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FIBRONECTIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; PROTEIN C JUN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL CYCLE CHECKPOINT; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EXTRACELLULAR MATRIX; GEL MOBILITY SHIFT ASSAY; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT;

AP-1; BERBERINE; CELL CYCLE; HIGH GLUCOSE; MESANGIAL CELLS; NF-ΚB;

ANIMALS; BERBERINE; CELL CYCLE; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EXTRACELLULAR MATRIX; FIBRONECTINS; GENE EXPRESSION REGULATION; GLUCOSE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MESANGIAL CELLS; PHOSPHORYLATION; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84894037956     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.01.022     Document Type: Article

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