메뉴 건너뛰기




Volumn 94, Issue 2, 2014, Pages 183-185

Curing TB with open science

Author keywords

Collaboration; Coordination; Data silos; Open science

Indexed keywords

BEDAQUILINE; BCG VACCINE; TUBERCULOSTATIC AGENT;

EID: 84893958919     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2013.10.002     Document Type: Article
Times cited : (3)

References (31)
  • 1
    • 84895500038 scopus 로고    scopus 로고
    • Computational models for neglected diseases: Gaps and opportunities
    • [in Press]
    • E.L. Ponder, J.S. Freundlich, M. Sarker, and S. Ekins Computational models for neglected diseases: gaps and opportunities Pharm Res 2013 [in Press]
    • (2013) Pharm Res
    • Ponder, E.L.1    Freundlich, J.S.2    Sarker, M.3    Ekins, S.4
  • 2
    • 84883789341 scopus 로고    scopus 로고
    • Rising to the challenge: New therapies for tuberculosis
    • E.B. Wong, K.A. Cohen, and W.R. Bishai Rising to the challenge: new therapies for tuberculosis Trends Microbiol 21 2013 493 501
    • (2013) Trends Microbiol , vol.21 , pp. 493-501
    • Wong, E.B.1    Cohen, K.A.2    Bishai, W.R.3
  • 3
    • 77953475812 scopus 로고    scopus 로고
    • Global tuberculosis drug development pipeline: The need and the reality
    • Z. Ma, C. Lienhardt, H. McIlleron, A.J. Nunn, and X. Wang Global tuberculosis drug development pipeline: the need and the reality Lancet 375 2010 2100 2109
    • (2010) Lancet , vol.375 , pp. 2100-2109
    • Ma, Z.1    Lienhardt, C.2    McIlleron, H.3    Nunn, A.J.4    Wang, X.5
  • 4
    • 84863584732 scopus 로고    scopus 로고
    • New drugs for the treatment of tuberculosis: Hope and reality
    • J.H. Grosset, T.G. Singer, and W.R. Bishai New drugs for the treatment of tuberculosis: hope and reality Int J Tuberc Lung Dis 16 2012 1005 1014
    • (2012) Int J Tuberc Lung Dis , vol.16 , pp. 1005-1014
    • Grosset, J.H.1    Singer, T.G.2    Bishai, W.R.3
  • 5
    • 84888635544 scopus 로고    scopus 로고
    • Combining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery
    • [in Press]
    • S. Ekins, J.S. Freundlich, J.V. Hobrath, E.L. White, and R.C. Reynolds Combining computational methods for hit to lead optimization in Mycobacterium tuberculosis drug discovery Pharm Res 2013 [in Press]
    • (2013) Pharm Res
    • Ekins, S.1    Freundlich, J.S.2    Hobrath, J.V.3    White, E.L.4    Reynolds, R.C.5
  • 6
    • 84856496490 scopus 로고    scopus 로고
    • High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv
    • R.C. Reynolds, S. Ananthan, E. Faaleolea, J.V. Hobrath, C.D. Kwong, C. Maddox, L. Rasmussen, M.I. Sosa, E. Thammasuvimol, E.L. White, W. Zhang, and J.A. Secrist III High throughput screening of a library based on kinase inhibitor scaffolds against Mycobacterium tuberculosis H37Rv Tuberculosis (Edinburgh, Scotland) 92 2012 72 83
    • (2012) Tuberculosis (Edinburgh, Scotland) , vol.92 , pp. 72-83
    • Reynolds, R.C.1    Ananthan, S.2    Faaleolea, E.3    Hobrath, J.V.4    Kwong, C.D.5
  • 13
    • 79959867973 scopus 로고    scopus 로고
    • A web server for predicting inhibitors against bacterial target GlmU protein
    • D. Singla, M. Anurag, D. Dash, and G.P. Raghava A web server for predicting inhibitors against bacterial target GlmU protein BMC Pharmacol 11 2011 5
    • (2011) BMC Pharmacol , vol.11 , pp. 5
    • Singla, D.1    Anurag, M.2    Dash, D.3    Raghava, G.P.4
  • 16
    • 84866888235 scopus 로고    scopus 로고
    • Open source drug discovery in practice: A case study
    • C. Ardal, and J.A. Rottingen Open source drug discovery in practice: a case study PLoS Negl Trop Dis 6 2012 e1827
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. 1827
    • Ardal, C.1    Rottingen, J.A.2
  • 17
    • 84875142445 scopus 로고    scopus 로고
    • South Africa warns of emergence of "totally" drug-resistant tuberculosis
    • A. Slomski South Africa warns of emergence of "totally" drug-resistant tuberculosis JAMA 309 2013 1097 1098
    • (2013) JAMA , vol.309 , pp. 1097-1098
    • Slomski, A.1
  • 18
    • 84884226265 scopus 로고    scopus 로고
    • The collaborative drug discovery (CDD) database
    • S. Ekins, and B.A. Bunin The collaborative drug discovery (CDD) database Methods Mol Biol (Clifton, NJ) 993 2013 139 154
    • (2013) Methods Mol Biol (Clifton, NJ) , vol.993 , pp. 139-154
    • Ekins, S.1    Bunin, B.A.2
  • 19
    • 84884218994 scopus 로고    scopus 로고
    • Computational models for tuberculosis drug discovery
    • S. Ekins, and J.S. Freundlich Computational models for tuberculosis drug discovery Methods Mol Biol (Clifton, NJ) 993 2013 245 262
    • (2013) Methods Mol Biol (Clifton, NJ) , vol.993 , pp. 245-262
    • Ekins, S.1    Freundlich, J.S.2
  • 20
    • 79952466815 scopus 로고    scopus 로고
    • Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery
    • S. Ekins, J.S. Freundlich, I. Choi, M. Sarker, and C. Talcott Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery Trends Microbiology 19 2011 65 74
    • (2011) Trends Microbiology , vol.19 , pp. 65-74
    • Ekins, S.1    Freundlich, J.S.2    Choi, I.3    Sarker, M.4    Talcott, C.5
  • 22
    • 84865262801 scopus 로고    scopus 로고
    • Open drug discovery teams: A chemistry mobile app for collaboration
    • S. Ekins, A.M. Clark, and A.J. Williams Open drug discovery teams: a chemistry mobile app for collaboration Mol Inform 31 2012 585 597
    • (2012) Mol Inform , vol.31 , pp. 585-597
    • Ekins, S.1    Clark, A.M.2    Williams, A.J.3
  • 23
    • 84877347898 scopus 로고    scopus 로고
    • TB mobile: A mobile app for anti-tuberculosis molecules with known targets
    • S. Ekins, A.M. Clark, and M. Sarker TB mobile: a mobile app for anti-tuberculosis molecules with known targets J Cheminform 5 2013 13
    • (2013) J Cheminform , vol.5 , pp. 13
    • Ekins, S.1    Clark, A.M.2    Sarker, M.3
  • 24
    • 84886953083 scopus 로고    scopus 로고
    • Multifaceted roles of ultra-rare and rare disease patients/parents in drug discovery
    • J. Wood, L. Sames, A. Moore, and S. Ekins Multifaceted roles of ultra-rare and rare disease patients/parents in drug discovery Drug Discov Today 18 21-22 November 2013 1043 1051
    • (2013) Drug Discov Today , vol.18 , Issue.2122 , pp. 1043-1051
    • Wood, J.1    Sames, L.2    Moore, A.3    Ekins, S.4
  • 25
    • 84862173050 scopus 로고    scopus 로고
    • Towards the development of a generalizable pre-clinical research pathway for orphan disease therapy
    • C.L. Beaulieu, S. Ekins, M. Samuels, K.M. Boycott, and A. MacKenzie Towards the development of a generalizable pre-clinical research pathway for orphan disease therapy Orphanet J Rare Dis 7 2012 39
    • (2012) Orphanet J Rare Dis , vol.7 , pp. 39
    • Beaulieu, C.L.1    Ekins, S.2    Samuels, M.3    Boycott, K.M.4    Mackenzie, A.5
  • 27
    • 77950531688 scopus 로고    scopus 로고
    • Precompetitive preclinical ADME/Tox data: Set it free on the web to facilitate computational model building to assist drug development
    • S. Ekins, and A.J. Williams Precompetitive preclinical ADME/Tox data: set it free on the web to facilitate computational model building to assist drug development Lab a Chip 10 2010 13 22
    • (2010) Lab A Chip , vol.10 , pp. 13-22
    • Ekins, S.1    Williams, A.J.2
  • 28
    • 77949269509 scopus 로고    scopus 로고
    • Reaching out to collaborators: Crowdsourcing for pharmaceutical research
    • S. Ekins, and A.J. Williams Reaching out to collaborators: crowdsourcing for pharmaceutical research Pharm Res 27 2010 393 395
    • (2010) Pharm Res , vol.27 , pp. 393-395
    • Ekins, S.1    Williams, A.J.2
  • 29
    • 84866901540 scopus 로고    scopus 로고
    • Why open drug discovery needs four simple rules for licensing data and models
    • A.J. Williams, J. Wilbanks, and S. Ekins Why open drug discovery needs four simple rules for licensing data and models PLoS Comput Biol 8 2012 e1002706
    • (2012) PLoS Comput Biol , vol.8 , pp. 1002706
    • Williams, A.J.1    Wilbanks, J.2    Ekins, S.3
  • 31
    • 71749108117 scopus 로고    scopus 로고
    • Competitive collaboration in the pharmaceutical and biotechnology industry
    • A. Bingham, and S. Ekins Competitive collaboration in the pharmaceutical and biotechnology industry Drug Disc Today 14 2009 1079 1081
    • (2009) Drug Disc Today , vol.14 , pp. 1079-1081
    • Bingham, A.1    Ekins, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.