Treatment of humeral shaft aseptic nonunions in elderly patients with opposite structural allograft, BMP-7,and mesenchymal stem cells

Orthopedics

Volumn 37, Issue 2, 2014, Pages

  Murena, Luigi ^a   Canton, Gianluca ^a   Vulcano, Ettore ^a   Surace, Michele Francesco ^a   Cherubino, Paolo ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; AGED, 80 AND OVER; BONE MORPHOGENETIC PROTEIN 7; BONE PLATES; BONE TRANSPLANTATION; COMBINED MODALITY THERAPY; DRUG IMPLANTS; FEMALE; FRACTURE FIXATION, INTERNAL; FRACTURES, UNUNITED; HUMANS; HUMERAL FRACTURES; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; OSTEONECROSIS; TREATMENT OUTCOME;

EID: 84893875565     PISSN: 01477447     EISSN: None     Source Type: Journal    
DOI: 10.3928/01477447-20140124-26     Document Type: Article

References (21)

1. King AR, Moran SL, Steinmann SP. Humeral nonunion. Hand Clin. 2007; 23:449-456.
2. Ring D, Kloen P, Kadzielski J, et al. Locking compression plates for osteoporotic nonunions of the diaphyseal humerus. Clin Or-thop Relat Res. 2004; 425:50-54.
3. Volgas DA, Stannard JP, Alonso JE. Nonunions of the humerus. Clin Orthop Relat Res. 2004; (419):46-50.
4. Pugh DM, McKee MD. Advances in the management of humeral non-union. J Am Acad Orthop Surg. 2003;11:48-59
5. Lin WP, Lin J. Allografting in locked nailing and interfragmentary wiring for humeral nonunions. Clin Orthop Relat Res. 2010; 468:852-860.
6. Prasarn ML, Achor T, Paul O, et al. Management of nonunions of the proximal humeral diaphysis. Injury. 2010; 41:1244-1248.
7. Marinelli A, Antonioli D, Guerra E, et al. Humeral shaft aseptic nonunion: Treatment with opposite cortical allograft struts. Musculoskelet Surg. 2009; 93:S21-S28.
8. Crawford CH III, Seligson D. Atrophic nonunion of humeral diaphysis treated with locking plate and recombinant bone morphogenetic protein: Nine cases. Am J Orthop. 2009; 38(11):567-570.
9. Hierholzer C, Sama D, Toro JB, et al. Plate fixation of ununited humeral shaft fractures: Effect of type of bone graft on healing. J Bone Joint Surg Am. 2006; 88(7):1442-1447.
10. Vidyadhara S, Vamsi K, Rao SK, et al. Use of intramedullary fibular strut graft: A novel adjunct to plating in the treatment of osteoporotic humeral shaft non-union. Int Orthop. 2009; 33:1009-1014.
11. Atalar AC, Kocaoglu M, Demirhan M, et al. Comparison of three different treatment modalities in the management of humeral shaft nonunions. J Orthop Trauma. 2008; 22:248-257.
12. Martinez AA, Cuenca J, Herrera A. Two-plate fixation for humeral shaft nonunions. J Orthop Surg. 2009; 17(2):135-138.
13. Vilaca PR Jr, Uezumi MK. Anterior minimally invasive bridge-plate technique for treatment of humeral shaft nonunion. J Orthop Trauma. 2012; 13:211-216.
14. Tomic S, Bumbasirevic M, Lesic A, et al. Ilizarov frame fixation without bone graft for atrophic humeral shaft nonunion: 28 patients with a minimum 2-year follow-up. J Orthop Trauma. 2007 21(8):549-556.
15. Bernard de Dompsure R, Peterb R, Hoffmeyerb R. Uninfected nonunion of the humeral diaphyses: Review of 21 patients treated with shingling compression plate, and autologous bone graft. Orthop Traumatol Surg Res. 2010; 96:139-146.
16. Gardner MJ, Griffith MH, Demetrakopoulos D, et al. Hybrid locked plating of osteoporotic fractures of the humerus. J Bone Joint Surg Am. 2006; 88:1962-1967.
17. Van Houwelingen AP, McKee MD. Treatment of osteopenic humeral shaft nonunion with compression plating, humeral cortical allograft struts, and bone grafting. J Orthop Trauma. 2005; 19(1):36-42.
18. Giannoudis PV, Einhorn TA, Marsh D. Fracture healing: The diamond concept. Injury. 2007; 38(suppl 4):S3-S6.
19. Hernigou P, Poignard A, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions: Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am. 2005; 87(7):1430-1437.
20. Vulcano E, Murena L, Cherubino P, et al. Treatment of severe post-traumatic bone defects with autologous stem cells loaded on allogeneic scaffolds. Surg Technol Int. 2012; 22:291-301.
21. Vulcano E, Murena L, Falvo DA, Baj A, Toniolo A, Cherubino P. Bone marrow aspirate and bone allograft to treat acetabular bone defects in revision total hip arthroplasty: A case series. Eur Rev Med Pharmacol Sci. 2013; 17(16):2240-2249.