PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner

International Journal of Molecular Medicine

Volumn 33, Issue 3, 2014, Pages 534-542

  Yokota, Jun ^a,b   Chosa, Naoyuki ^a   Sawada, Shunsuke ^a,c   Okubo, Naoto ^a,d   Takahashi, Noriko ^a   Hasegawa, Tomokazu ^e   Kondo, Hisatomo ^b   Ishisaki, Akira ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b Department of Prosthodontics and Oral Implantology ^*  (Japan)

^c Division of Periodontology   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e TOKUSHIMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Extracellular signal regulated kinase; Mesenchymal stem cells; Osteogenic differentiation; Phosphoinositide 3 kinase; Platelet derived growth factor; Proliferation; Transforming growth factor

Indexed keywords

BONE MARROW CELLS; CELL DIFFERENTIATION; ELAFIN; HUMANS; MAP KINASE KINASE KINASES; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84893868549     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1606     Document Type: Article

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