Evaluation of the efficacy and safety of tranexamic acid for reducing blood loss in bilateral total knee arthroplasty

Journal of Arthroplasty

Volumn 29, Issue 3, 2014, Pages 501-503

  Karam, Joseph A ^a   Bloomfield, Michael R ^a   DiIorio, Timothy M ^a   Irizarry, Andrea M ^a   Sharkey, Peter F ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b ROTHMAN INSTITUTE   (United States)

Author keywords

Bilateral; Bleeding control; Blood loss; Total knee arthroplasty; Tranexamic acid; Transfusion

Indexed keywords

BILATERAL; BLEEDING CONTROL; BLOOD LOSS; TOTAL KNEE ARTHROPLASTY; TRANEXAMIC ACID; TRANSFUSION;

ADMINISTRATION, INTRAVENOUS; AGED; ANTIFIBRINOLYTIC AGENTS; ARTHROPLASTY, REPLACEMENT, KNEE; BLOOD LOSS, SURGICAL; FEMALE; HUMANS; MALE; MIDDLE AGED; POSTOPERATIVE HEMORRHAGE; RETROSPECTIVE STUDIES; TRANEXAMIC ACID; TREATMENT OUTCOME;

EID: 84893864672     PISSN: 08835403     EISSN: 15328406     Source Type: Journal    
DOI: 10.1016/j.arth.2013.08.005     Document Type: Article

References (30)

1. Markar S.R., Jones G.G., Karthikesalingam A., et al. Transfusion drains versus suction drains in total knee replacement: meta-analysis. Knee Surg Sports Traumatol Arthrosc 2012, 20(9):1766.
2. Bezwada H.P., Nazarian D.G., Henry D.H., et al. Preoperative use of recombinant human erythropoietin before total joint arthroplasty. J Bone Joint Surg Am 2003, 85-A(9):1795.
3. Breakwell, Getty, Dobson The efficacy of autologous blood transfusion in bilateral total knee arthroplasty. Knee 2000, 7(3):145.
4. Sculco T.P., Baldini A., Keating E.M. Blood management in total joint arthroplasty. Instr Course Lect 2005, 54:51.
5. Tang J., Wu G., Peng L. Pharmacokinetics of propofol in patients undergoing total hip replacement: effect of acute hypervolemic hemodilution. Anaesthesist 2011, 60(9):835.
6. Dellinger E.P., Anaya D.A. Infectious and immunologic consequences of blood transfusion. Crit Care 2004, 8(Suppl 2):S18.
7. Pulido L., Ghanem E., Joshi A., et al. Periprosthetic joint infection: the incidence, timing, and predisposing factors. Clin Orthop Relat Res 2008, 466(7):1710.
8. Madjdpour C., Spahn D.R. Allogeneic red blood cell transfusions: efficacy, risks, alternatives and indications. Br J Anaesth 2005, 95(1):33.
9. Klein H.G. Allogeneic transfusion risks in the surgical patient. Am J Surg 1995, 170(6A Suppl):21S.
10. Hendrickson J.E., Hillyer C.D. Noninfectious serious hazards of transfusion. Anesth Analg 2009, 108(3):759.
11. Alshryda S., Sarda P., Sukeik M., et al. Tranexamic acid in total knee replacement: a systematic review and meta-analysis. J Bone Joint Surg Br 2011, 93(12):1577.
12. Zhang H., Chen J., Chen F., et al. The effect of tranexamic acid on blood loss and use of blood products in total knee arthroplasty: a meta-analysis. Knee Surg Sports Traumatol Arthrosc 2012, 20(9):1742.
13. Yang Z.-G., Chen W.-P., Wu L.-D. Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis. J Bone Joint Surg Am 2012, 94(13):1153.
14. Niskanen R.O., Korkala O.L. Tranexamic acid reduces blood loss in cemented hip arthroplasty: a randomized, double-blind study of 39 patients with osteoarthritis. Acta Orthop 2005, 76(6):829.
15. Hiippala S.T., Strid L.J., Wennerstrand M.I., et al. Tranexamic acid radically decreases blood loss and transfusions associated with total knee arthroplasty. Anesth Analg 1997, 84(4):839.
16. Yamasaki S., Masuhara K., Fuji T. Tranexamic acid reduces postoperative blood loss in cementless total hip arthroplasty. J Bone Joint Surg Am 2005, 87(4):766.
17. Johansson T., Pettersson L.-G., Lisander B. Tranexamic acid in total hip arthroplasty saves blood and money: a randomized, double-blind study in 100 patients. Acta Orthop 2005, 76(3):314.
18. Husted H., Blønd L., Sonne-Holm S., et al. Tranexamic acid reduces blood loss and blood transfusions in primary total hip arthroplasty: a prospective randomized double-blind study in 40 patients. Acta Orthop Scand 2003, 74(6):665.
19. Alvarez J.C., Santiveri F.X., Ramos I., et al. Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied. Transfusion 2008, 48(3):519.
20. Mutsuzaki H., Ikeda K. Intra-articular injection of tranexamic acid via a drain plus drain-clamping to reduce blood loss in cementless total knee arthroplasty. J Orthop Surg Res. 2012, 7:32.
21. Sule S.D., Bartlett S., Parker A., et al. Preoperative autologous blood donation by arthritis patients is associated with preoperative anemia and perioperative transfusion. J Clin Rheumatol 2004, 10(5):252.
22. Parvizi J., Chaudhry S., Rasouli M.R., et al. Who needs autologous blood donation in joint replacement?. J Knee Surg 2011, 24(1):25.
23. Hatzidakis A.M., Mendlick R.M., McKillip T., et al. Preoperative autologous donation for total joint arthroplasty. An analysis of risk factors for allogenic transfusion. J Bone Joint Surg Am 2000, 82(1):89.
24. Bierbaum B.E., Callaghan J.J., Galante J.O., et al. An analysis of blood management in patients having a total hip or knee arthroplasty. J Bone Joint Surg Am 1999, 81(1):2.
25. Friedman R.J. Limit the bleeding, limit the pain in total hip and knee arthroplasty. Orthopedics 2010, 33(9 Suppl):11.
26. Bullock D.P., Sporer S.M., Shirreffs T.G. Comparison of simultaneous bilateral with unilateral total knee arthroplasty in terms of perioperative complications. J Bone Joint Surg Am 2003, 85-A(10):1981.
27. MacGillivray R.G., Tarabichi S.B., Hawari M.F., et al. Tranexamic acid to reduce blood loss after bilateral total knee arthroplasty: a prospective, randomized double blind study. J Arthroplasty 2011, 26(1):24.
28. Dhillon M.S., Bali K., Prabhakar S. Tranexamic acid for control of blood loss in bilateral total knee replacement in a single stage. Indian J Orthop 2011, 45(2):148.
29. Sehat K.R., Evans R.L., Newman J.H. Hidden blood loss following hip and knee arthroplasty. Correct management of blood loss should take hidden loss into account. J Bone Joint Surg Br 2004, 86(4):561.
30. White R.H., Zhou H., Romano P.S. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost 2003, 90(3):446.