The neural basis of impaired self-awareness after traumatic brain injury

Brain

Volumn 137, Issue 2, 2014, Pages 586-597

  Ham, Timothy E ^a,b   Bonnelle, Valerie ^c   Hellyer, Peter ^a   Jilka, Sagar ^a,d   Robertson, Ian H ^e   Leech, Robert ^a   Sharp, David J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF LONDON   (United Kingdom)

^e TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

fronto parietal control network; functional connectivity; salience network; self awareness; traumatic brain injury

Indexed keywords

ADULT; AGED; ANTERIOR CINGULATE; ARTICLE; AXONAL INJURY; BRAIN FUNCTION; BRAIN NETWORK FUNCTION; COGNITIVE DEFECT; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; DISABILITY; EVOKED RESPONSE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; INFERIOR FRONTAL GYRUS; INJURY SEVERITY; INSULA; MAJOR CLINICAL STUDY; MALE; MIDDLE FRONTAL GYRUS; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PUTAMEN; RESPONSE TIME; SELF AWARENESS IMPAIRMENT; SELF CONCEPT; TRACTOGRAPHY; TRAUMATIC BRAIN INJURY; VISUAL SYSTEM; WHITE MATTER; YOUNG ADULT;

FRONTO-PARIETAL CONTROL NETWORK; FUNCTIONAL CONNECTIVITY; SALIENCE NETWORK; SELF-AWARENESS; TRAUMATIC BRAIN INJURY;

ADOLESCENT; ADULT; AGED; AWARENESS; BRAIN; BRAIN INJURIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE NET; NEURONS; PSYCHOMOTOR PERFORMANCE; YOUNG ADULT;

EID: 84893822838     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt350     Document Type: Article

References (74)

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38. Baltes PB. The aging mind: Potential and limits. Gerontologist 1993; 33: 580-94
39. Beckmann CF, DeLuca M, Devlin JT, Smith SM. Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond B Biol Sci 2005; 360: 1001-13
40. Bekker EM, Overtoom CC, Kenemans JL, Kooij JJ, De Noord I, Buitelaar JK, et al. Stopping and changing in adults with ADHD. Psychol Med 2005; 35: 807-16
41. Boly M, Balteau E, Schnakers C, Degueldre C, Moonen G, Luxen A, et al. Baseline brain activity fluctuations predict somatosensory perception in humans. Proc Natl Acad Sci USA 2007; 104: 12187-92
42. Bonnelle V, Ham TE, Leech R, Kinnunen KM, Mehta MA, Greenwood RJ, et al. Salience network integrity predicts default mode network function after traumatic brain injury. Proc Natl Acad Sci USA 2012; 109: 4690-5
43. Bonnelle V, Leech R, Kinnunen KM, Ham TE, Beckmann CF, De Boissezon X, et al. Default mode network connectivity predicts sustained attention deficits after traumatic brain injury. J Neurosci 2011; 31: 13442-51
44. Botvinick MM, Cohen JD, Carter CS. Conflict monitoring and anterior cingulate cortex: An update. Trends Cogn Sci 2004; 8: 539-46
45. Brett M, Leff AP, Rorden C, Ashburner J. Spatial normalization of brain images with focal lesions using cost function masking. Neuroimage 2001; 14: 486-500
46. Cabeza R, Anderson ND, Locantore JK, McIntosh AR. Aging gracefully: Compensatory brain activity in high-performing older adults. Neuroimage 2002; 17: 1394-402
47. Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D, Cohen JD. Anterior cingulate cortex, error detection, and the online monitoring of performance. Science 1998; 280: 747-9
48. Corbetta M, Shulman GL. Spatial neglect and attention networks. Annu Rev Neurosci 2011; 34: 569-99
49. Craig AD. How do you feel-now? The anterior insula and human awareness. Nat Rev Neurosci 2009; 10: 59-70
50. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, et al. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA 2006; 103: 13848-53
51. Dehaene S, Posner MI, Tucker DM. Localization of a Neural System for Error-Detection and Compensation. Psychol Sci 1994; 5: 303-5
52. Dreer LE, Devivo MJ, Novack TA, Marson DC. Financial capacity following traumatic brain injury: A six-month longitudinal study. Rehabil Psychol 2012; 57: 5-12
53. Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, et al. Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc Natl Acad Sci USA 2009; 106: 7209-14
54. Fleming JM, Strong J, Ashton R. Self-Awareness of deficits in adults with traumatic brain injury: How best to measure? Brain Inj 1996; 10: 1-15
55. Fox MD, Snyder AZ, Zacks JM, Raichle ME. Coherent spontaneous activity accounts for trial-To-Trial variability in human evoked brain responses. Nat Neurosci 2006; 9: 23-5
56. Grace J, Stout JC, Malloy PF. Assessing frontal lobe behavioral syndromes with the frontal lobe personality scale. Assessment 1999; 6: 269-84
57. Ham T, Leff A, de Boissezon X, Joffe A, Sharp DJ. Cognitive control and the salience network: An investigation of error processing and effective connectivity. J Neurosci 2013; 33: 7091-8
58. Ham TE, de Boissezon X, Leff A, Beckmann C, Hughes E, Kinnunen KM, et al. Distinct frontal networks are involved in adapting to internally and externally signaled errors. Cereb Cortex 2012; 23: 703-13
59. Ham TE, Sharp DJ. How can investigation of network function inform rehabilitation after traumatic brain injury? Curr Opin Neurol 2012; 25: 662-9
60. Hart T, Giovannetti T, Montgomery MW, Schwartz MF. Awareness of errors in naturalistic action after traumatic brain injury. J Head Trauma Rehab 1998; 13: 16-28
61. He BJ, Snyder AZ, Vincent JL, Epstein A, Shulman GL, Corbetta M. Breakdown of functional connectivity in frontoparietal networks underlies behavioral deficits in spatial neglect. Neuron 2007; 53: 905-18
62. Hellyer PJ, Leech R, Ham TE, Bonnelle V, Sharp DJ. Individual prediction of white matter injury following traumatic brain injury. Ann Neurol 2013; 73: 489-9
63. Hesselmann G, Kell CA, Eger E, Kleinschmidt A. Spontaneous local variations in ongoing neural activity bias perceptual decisions. Proc Natl Acad Sci USA 2008; 105: 10984-9
64. Husain M, Shapiro K, Martin J, Kennard C. Abnormal temporal dynamics of visual attention in spatial neglect patients. Nature 1997; 385: 154-6
65. Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17: 825-41
66. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal 2001; 5: 143-56
67. Johnson SC, Baxter LC, Wilder LS, Pipe JG, Heiserman JE, Prigatano GP. Neural correlates of self-reflection. Brain 2002; 125: 1808-14
68. Larson MJ, Kaufman DA, Schmalfuss IM, Perlstein WM. Performance monitoring, error processing, and evaluative control following severe TBI. J Int Neuropsych Soc 2007; 13: 961-71
69. Li CS, Huang C, Yan P, Paliwal P, Constable RT, Sinha R. Neural correlates of post-error slowing during a stop signal task: A functional magnetic resonance imaging study. J Cognitive Neurosci 2008; 20: 1021-9
70. Logan GD, Cowan WB, Davis KA. On the ability to inhibit simple and choice reaction time responses: A model and a method. J Exp Psychol Human 1984; 10: 276-91
71. Malec JF, Brown AW, Leibson CL, Flaada JT, Mandrekar JN, Diehl NN, et al. The mayo classification system for traumatic brain injury severity. J Neurotraum 2007; 24: 1417-24
72. Martin RC, Triebel K, Dreer LE, Novack TA, Turner C, Marson DC. Neurocognitive predictors of financial capacity in traumatic brain injury. J Head Trauma Rehab 2012; 27: E81-90
73. Mesulam MM. Large-scale neurocognitive networks and distributed processing for attention, language, and memory. Ann Neurol 1990; 28: 597-613
74. Modirrousta M, Fellows LK. Dorsal medial prefrontal cortex plays a necessary role in rapid error prediction in humans. J Neurosci 2008; 28: 14000-5