메뉴 건너뛰기




Volumn 35, Issue 1, 2014, Pages 131-141

Biomarkers in COPD

Author keywords

Chronic bronchitis; Emphysema; Outcomes; Smoking; Treatment

Indexed keywords

CHRONIC BRONCHITIS; EMPHYSEMA; OUTCOMES; SMOKING; TREATMENT;

EID: 84893810882     PISSN: 02725231     EISSN: 15578216     Source Type: Journal    
DOI: 10.1016/j.ccm.2013.09.006     Document Type: Review
Times cited : (45)

References (49)
  • 1
    • 79551603829 scopus 로고    scopus 로고
    • Characterisation of COPD heterogeneity in the ECLIPSE cohort
    • Agusti A., Calverley P., Celli B., et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res 2010, 11:122-136.
    • (2010) Respir Res , vol.11 , pp. 122-136
    • Agusti, A.1    Calverley, P.2    Celli, B.3
  • 2
    • 34548660457 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Rabe K.F., Hurd S., Anzueto A., et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007, 176:532-555.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 532-555
    • Rabe, K.F.1    Hurd, S.2    Anzueto, A.3
  • 3
    • 79955498646 scopus 로고    scopus 로고
    • Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine
    • Agusti A., Sobradillo P., Celli B. Addressing the complexity of chronic obstructive pulmonary disease: from phenotypes and biomarkers to scale-free networks, systems biology, and P4 medicine. Am J Respir Crit Care Med 2011, 183:1129-1137.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1129-1137
    • Agusti, A.1    Sobradillo, P.2    Celli, B.3
  • 4
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD Executive Summary
    • Vestbo J., Hurd S.S., Agusti A.G., et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD Executive Summary. Am J Respir Crit Care Med 2013, 187(4):347-365.
    • (2013) Am J Respir Crit Care Med , vol.187 , Issue.4 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agusti, A.G.3
  • 5
    • 33646565124 scopus 로고    scopus 로고
    • Outcomes and markers in the assessment of chronic obstructive pulmonary disease
    • Jones P.W., Agusti A.G.N. Outcomes and markers in the assessment of chronic obstructive pulmonary disease. Eur Respir J 2006, 27:822-832.
    • (2006) Eur Respir J , vol.27 , pp. 822-832
    • Jones, P.W.1    Agusti, A.G.N.2
  • 6
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, gold executive summary
    • Vestbo J., Hurd S.S., Agusti A.G., et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, gold executive summary. Am J Respir Crit Care Med 2013, 187:347-365.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agusti, A.G.3
  • 7
    • 80053350305 scopus 로고    scopus 로고
    • Changes in forced expiratory volume in 1 second over time in COPD
    • Vestbo J., Edwards L.D., Scanlon P.D., et al. Changes in forced expiratory volume in 1 second over time in COPD. NEngl J Med 2011, 365:1184-1192.
    • (2011) NEngl J Med , vol.365 , pp. 1184-1192
    • Vestbo, J.1    Edwards, L.D.2    Scanlon, P.D.3
  • 8
    • 1442306237 scopus 로고    scopus 로고
    • The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease
    • Celli B.R., Cote C.G., Marin J.M., et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. NEngl J Med 2004, 350:1005-1012.
    • (2004) NEngl J Med , vol.350 , pp. 1005-1012
    • Celli, B.R.1    Cote, C.G.2    Marin, J.M.3
  • 9
    • 40649117704 scopus 로고    scopus 로고
    • Outcomes for COPD pharmacological trials: from lung function to biomarkers
    • Cazzola M., MacNee W., Martinez F.J., et al. Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J 2008, 31:416-469.
    • (2008) Eur Respir J , vol.31 , pp. 416-469
    • Cazzola, M.1    MacNee, W.2    Martinez, F.J.3
  • 10
    • 33847327365 scopus 로고    scopus 로고
    • Benchmarks for the assessment of novel cardiovascular biomarkers
    • Morrow D.A., de Lemos J.A. Benchmarks for the assessment of novel cardiovascular biomarkers. Circulation 2007, 115:949-952.
    • (2007) Circulation , vol.115 , pp. 949-952
    • Morrow, D.A.1    de Lemos, J.A.2
  • 11
    • 34547781171 scopus 로고    scopus 로고
    • Biomarkers in COPD: time for a deep breath
    • Stockley R.A. Biomarkers in COPD: time for a deep breath. Thorax 2007, 62:657-660.
    • (2007) Thorax , vol.62 , pp. 657-660
    • Stockley, R.A.1
  • 12
    • 84879412209 scopus 로고    scopus 로고
    • Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease
    • Duvoix A., Dickens J., Haq I., et al. Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease. Thorax 2013, 68:670-676.
    • (2013) Thorax , vol.68 , pp. 670-676
    • Duvoix, A.1    Dickens, J.2    Haq, I.3
  • 13
    • 84926426742 scopus 로고    scopus 로고
    • Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis
    • Danesh J., Lewington S., Thompson S.G., et al. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA 2005, 294:1799-1809.
    • (2005) JAMA , vol.294 , pp. 1799-1809
    • Danesh, J.1    Lewington, S.2    Thompson, S.G.3
  • 14
    • 84860265548 scopus 로고    scopus 로고
    • Fibrinogen, chronic obstructive pulmonary disease (COPD) and outcomes in two United States cohorts
    • Valvi D., Mannino D.M., Mullerova H., et al. Fibrinogen, chronic obstructive pulmonary disease (COPD) and outcomes in two United States cohorts. Int J Chron Obstruct Pulmon Dis 2012, 7:173-182.
    • (2012) Int J Chron Obstruct Pulmon Dis , vol.7 , pp. 173-182
    • Valvi, D.1    Mannino, D.M.2    Mullerova, H.3
  • 15
    • 84861410475 scopus 로고    scopus 로고
    • Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease
    • Celli B.R., Locantore N., Yates J., et al. Inflammatory biomarkers improve clinical prediction of mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012, 185:1065-1072.
    • (2012) Am J Respir Crit Care Med , vol.185 , pp. 1065-1072
    • Celli, B.R.1    Locantore, N.2    Yates, J.3
  • 16
    • 77956689733 scopus 로고    scopus 로고
    • Susceptibility toexacerbation in chronic obstructive pulmonary disease
    • Hurst J.R., Vestbo J., Anzueto A., et al. Susceptibility toexacerbation in chronic obstructive pulmonary disease. NEngl J Med 2010, 363:1128-1138.
    • (2010) NEngl J Med , vol.363 , pp. 1128-1138
    • Hurst, J.R.1    Vestbo, J.2    Anzueto, A.3
  • 17
    • 39449106895 scopus 로고    scopus 로고
    • Increased systemic inflammation is a risk factor for COPD exacerbations
    • Groenewegen K.H., Postma D.S., Hop W.C., et al. Increased systemic inflammation is a risk factor for COPD exacerbations. Chest 2008, 133:350-357.
    • (2008) Chest , vol.133 , pp. 350-357
    • Groenewegen, K.H.1    Postma, D.S.2    Hop, W.C.3
  • 18
    • 0035883488 scopus 로고    scopus 로고
    • Elevated plasma fibrinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary disease
    • Dahl M., Tybjaerg-Hansen A., Vestbo J., et al. Elevated plasma fibrinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001, 164:1008-1011.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1008-1011
    • Dahl, M.1    Tybjaerg-Hansen, A.2    Vestbo, J.3
  • 19
    • 56049098169 scopus 로고    scopus 로고
    • Microalbuminuria, von Willebrand factor and fibrinogen levels as markers of the severity in COPD exacerbation
    • Polatli M., Cakir A., Cildag O., et al. Microalbuminuria, von Willebrand factor and fibrinogen levels as markers of the severity in COPD exacerbation. JThromb Thrombolysis 2008, 26:97-102.
    • (2008) JThromb Thrombolysis , vol.26 , pp. 97-102
    • Polatli, M.1    Cakir, A.2    Cildag, O.3
  • 20
    • 67349226387 scopus 로고    scopus 로고
    • Clinical, functional and biochemical changes during recovery from COPD exacerbations
    • Koutsokera A., Kiropoulos T.S., Nikoulis D.J., et al. Clinical, functional and biochemical changes during recovery from COPD exacerbations. Respir Med 2009, 103:919-926.
    • (2009) Respir Med , vol.103 , pp. 919-926
    • Koutsokera, A.1    Kiropoulos, T.S.2    Nikoulis, D.J.3
  • 21
    • 53449100116 scopus 로고    scopus 로고
    • Circulating vascular endothelial growth factor and systemic inflammatory markers in patients with stable and exacerbated chronic obstructive pulmonary disease
    • Valipour A., Schreder M., Wolzt M., et al. Circulating vascular endothelial growth factor and systemic inflammatory markers in patients with stable and exacerbated chronic obstructive pulmonary disease. Clin Sci (Lond) 2008, 115:225-232.
    • (2008) Clin Sci (Lond) , vol.115 , pp. 225-232
    • Valipour, A.1    Schreder, M.2    Wolzt, M.3
  • 22
    • 38849205365 scopus 로고    scopus 로고
    • Serum amyloid as a biomarker of acute exacerbations of chronic obstructive pulmonary disease
    • Bozinovski S., Hutchinson A., Thompson M., et al. Serum amyloid as a biomarker of acute exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008, 177:269-278.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 269-278
    • Bozinovski, S.1    Hutchinson, A.2    Thompson, M.3
  • 23
    • 34248641015 scopus 로고    scopus 로고
    • C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus
    • Ridker P.M. C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus. JAm Coll Cardiol 2007, 49:2129-2138.
    • (2007) JAm Coll Cardiol , vol.49 , pp. 2129-2138
    • Ridker, P.M.1
  • 24
    • 3142517968 scopus 로고    scopus 로고
    • Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis
    • Gan W.Q., Man S.F., Senthilselvan A., et al. Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis. Thorax 2004, 59:574-580.
    • (2004) Thorax , vol.59 , pp. 574-580
    • Gan, W.Q.1    Man, S.F.2    Senthilselvan, A.3
  • 25
    • 33749998694 scopus 로고    scopus 로고
    • C-reactive protein and mortality in mild to moderate chronic obstructive pulmonary disease
    • Man S.F., Connett J.E., Anthonisen N.R., et al. C-reactive protein and mortality in mild to moderate chronic obstructive pulmonary disease. Thorax 2006, 61:849-853.
    • (2006) Thorax , vol.61 , pp. 849-853
    • Man, S.F.1    Connett, J.E.2    Anthonisen, N.R.3
  • 26
    • 33846785205 scopus 로고    scopus 로고
    • C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease
    • Dahl M., Vestbo J., Lange P., et al. C-reactive protein as a predictor of prognosis in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007, 175:250-255.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 250-255
    • Dahl, M.1    Vestbo, J.2    Lange, P.3
  • 27
    • 33749817683 scopus 로고    scopus 로고
    • Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease
    • Hurst J.R., Donaldson G.C., Perera W.R., et al. Use of plasma biomarkers at exacerbation of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006, 174:867-874.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 867-874
    • Hurst, J.R.1    Donaldson, G.C.2    Perera, W.R.3
  • 28
    • 84869223241 scopus 로고    scopus 로고
    • Inflammatory biomarkers and comorbidities in chronic obstructive pulmonary disease
    • Thomsen M., Dahl M., Lange P., et al. Inflammatory biomarkers and comorbidities in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012, 186:982-988.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 982-988
    • Thomsen, M.1    Dahl, M.2    Lange, P.3
  • 29
    • 0037465734 scopus 로고    scopus 로고
    • Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? the potential role of systemic inflammation in chronic obstructive pulmonary disease
    • Sin D.D., Man S.F. Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? the potential role of systemic inflammation in chronic obstructive pulmonary disease. Circulation 2003, 107:1514-1519.
    • (2003) Circulation , vol.107 , pp. 1514-1519
    • Sin, D.D.1    Man, S.F.2
  • 30
    • 80155137352 scopus 로고    scopus 로고
    • COPD association and repeatability of blood biomarkers in the ECLIPSE cohort
    • Dickens J.A., Miller B.E., Edwards L.D., et al. COPD association and repeatability of blood biomarkers in the ECLIPSE cohort. Respir Res 2011, 12:146.
    • (2011) Respir Res , vol.12 , pp. 146
    • Dickens, J.A.1    Miller, B.E.2    Edwards, L.D.3
  • 31
    • 79151480125 scopus 로고    scopus 로고
    • Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD
    • Wu L., Ma L., Nicholson L.F., et al. Advanced glycation end products and its receptor (RAGE) are increased in patients with COPD. Respir Med 2011, 105:329-336.
    • (2011) Respir Med , vol.105 , pp. 329-336
    • Wu, L.1    Ma, L.2    Nicholson, L.F.3
  • 32
    • 79959778582 scopus 로고    scopus 로고
    • Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study
    • Miniati M., Monti S., Basta G., et al. Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study. Respir Res 2011, 12:37.
    • (2011) Respir Res , vol.12 , pp. 37
    • Miniati, M.1    Monti, S.2    Basta, G.3
  • 33
    • 79953687947 scopus 로고    scopus 로고
    • Reduced soluble receptor for advanced glycation end products in chronic obstructive pulmonary disease
    • Smith D.J., Yerkovich S.T., Towers M.A., et al. Reduced soluble receptor for advanced glycation end products in chronic obstructive pulmonary disease. Eur Respir J 2011, 37:516-522.
    • (2011) Eur Respir J , vol.37 , pp. 516-522
    • Smith, D.J.1    Yerkovich, S.T.2    Towers, M.A.3
  • 34
    • 79951712620 scopus 로고    scopus 로고
    • Serum bilirubin and risk of respiratory disease and death
    • Horsfall L.J., Rait G., Walters K., et al. Serum bilirubin and risk of respiratory disease and death. JAMA 2011, 305:691-697.
    • (2011) JAMA , vol.305 , pp. 691-697
    • Horsfall, L.J.1    Rait, G.2    Walters, K.3
  • 35
    • 69249133317 scopus 로고    scopus 로고
    • Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD
    • Tal-Singer, and on behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigatorsand on behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators
    • Lomas D.A., Silverman E.K., Edwards L.D., et al. Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD. Eur Respir J 2009, 34:95-102. Tal-Singer, and on behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigatorsand on behalf of the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints study investigators.
    • (2009) Eur Respir J , vol.34 , pp. 95-102
    • Lomas, D.A.1    Silverman, E.K.2    Edwards, L.D.3
  • 36
    • 44449101166 scopus 로고    scopus 로고
    • The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease
    • Sin D.D., Man S.F.P., Marciniuk D.D., et al. The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2008, 177:1207-1214.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1207-1214
    • Sin, D.D.1    Man, S.F.P.2    Marciniuk, D.D.3
  • 37
    • 80051539685 scopus 로고    scopus 로고
    • Circulating surfactant protein-D and the risk of cardiovascular morbidity and mortality
    • Hill J., Heslop C., Man S.F., et al. Circulating surfactant protein-D and the risk of cardiovascular morbidity and mortality. Eur Heart J 2011, 32:1918-1925.
    • (2011) Eur Heart J , vol.32 , pp. 1918-1925
    • Hill, J.1    Heslop, C.2    Man, S.F.3
  • 38
    • 57149112816 scopus 로고    scopus 로고
    • Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort
    • Lomas D.A., Silverman E.K., Edwards L.D., et al. Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort. Thorax 2008, 63:1058-1063.
    • (2008) Thorax , vol.63 , pp. 1058-1063
    • Lomas, D.A.1    Silverman, E.K.2    Edwards, L.D.3
  • 39
    • 84867129700 scopus 로고    scopus 로고
    • The complex relationship of serum adiponectin to COPD outcomes COPD and adiponectin
    • Yoon H.I., Li Y., Man S.F., et al. The complex relationship of serum adiponectin to COPD outcomes COPD and adiponectin. Chest 2012, 142:893-899.
    • (2012) Chest , vol.142 , pp. 893-899
    • Yoon, H.I.1    Li, Y.2    Man, S.F.3
  • 40
    • 84863447204 scopus 로고    scopus 로고
    • Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease
    • Bafadhel M., McKenna S., Terry S., et al. Blood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012, 186:48-55.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 48-55
    • Bafadhel, M.1    McKenna, S.2    Terry, S.3
  • 41
    • 84872684173 scopus 로고    scopus 로고
    • TNFa antagonists for acute exacerbations of COPD: a randomised double-blind controlled trial
    • Aaron S.D., Vandemheen K.L., Maltais F., et al. TNFa antagonists for acute exacerbations of COPD: a randomised double-blind controlled trial. Thorax 2013, 68:142-148.
    • (2013) Thorax , vol.68 , pp. 142-148
    • Aaron, S.D.1    Vandemheen, K.L.2    Maltais, F.3
  • 42
    • 33846823024 scopus 로고    scopus 로고
    • Resolution of inflammation: state of the art, definitions and terms
    • Serhan C.N., Brain S.D., Buckley C.D., et al. Resolution of inflammation: state of the art, definitions and terms. FASEB J 2007, 21:325-332.
    • (2007) FASEB J , vol.21 , pp. 325-332
    • Serhan, C.N.1    Brain, S.D.2    Buckley, C.D.3
  • 43
    • 2942720573 scopus 로고    scopus 로고
    • The nature of small-airway obstruction in chronic obstructive pulmonary disease
    • Hogg J.C., Chu F., Utokaparch S., et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. NEngl J Med 2004, 350:2645-2653.
    • (2004) NEngl J Med , vol.350 , pp. 2645-2653
    • Hogg, J.C.1    Chu, F.2    Utokaparch, S.3
  • 44
    • 66649127821 scopus 로고    scopus 로고
    • Immunological aspects of COPD
    • Cosio M., Saetta M., Agusti A. Immunological aspects of COPD. NEngl J Med 2009, 360:2445-2454.
    • (2009) NEngl J Med , vol.360 , pp. 2445-2454
    • Cosio, M.1    Saetta, M.2    Agusti, A.3
  • 45
    • 84868636677 scopus 로고    scopus 로고
    • An investigation of the resolution of inflammation (catabasis) in COPD
    • Noguera A., Gomez C., Faner R., et al. An investigation of the resolution of inflammation (catabasis) in COPD. Respir Res 2012, 13:101.
    • (2012) Respir Res , vol.13 , pp. 101
    • Noguera, A.1    Gomez, C.2    Faner, R.3
  • 46
    • 84862100999 scopus 로고    scopus 로고
    • Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype
    • Agusti A., Edwards L.D., Rennard S.I., et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. PLoS ONE 2012, 7:e37483.
    • (2012) PLoS ONE , vol.7
    • Agusti, A.1    Edwards, L.D.2    Rennard, S.I.3
  • 47
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: a network-based approach to human disease
    • Barabasi A.L., Gulbahce N., Loscalzo J. Network medicine: a network-based approach to human disease. Nat Rev Genet 2011, 12:56-68.
    • (2011) Nat Rev Genet , vol.12 , pp. 56-68
    • Barabasi, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 48
    • 84863952703 scopus 로고    scopus 로고
    • Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease
    • Divo M., Cote C., de Torres J.P., et al. Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2012, 186:155-161.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 155-161
    • Divo, M.1    Cote, C.2    de Torres, J.P.3
  • 49
    • 73449130797 scopus 로고    scopus 로고
    • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis
    • Kaptoge S., Di A.E., Lowe G., et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 2010, 375:132-140.
    • (2010) Lancet , vol.375 , pp. 132-140
    • Kaptoge, S.1    Di, A.E.2    Lowe, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.