-
1
-
-
62849104641
-
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: A randomized, open-label, phase III study
-
Fenaux P, Mufti GJ, Hellströ m-Lindberg E, Santini V, Finelli C, Giagounidis A et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomized, open-label, phase III study. Lancet Oncol 2009; 10: 223-232.
-
(2009)
Lancet Oncol
, vol.10
, pp. 223-232
-
-
Fenaux, P.M.1
-
2
-
-
77949823230
-
Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: Azacitidine compared with low-dose ara-C
-
Fenaux P, Gattermann N, Seymour JF, Hellströ m-Lindberg E, Mufti GJ, Duehrsen U et al. Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low-dose ara-C. Br J Haematol 2010; 149: 244-249.
-
(2010)
Br J Haematol
, vol.149
, pp. 244-249
-
-
Fenaux, P.1
Gattermann, N.2
Seymour, J.F.3
Hellströ M-Lindberg, E.4
Mufti, G.J.5
Duehrsen, U.6
-
3
-
-
67349200930
-
The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute meloid leukemia cells
-
Flotho C, Claus R, Batz C, Schneider M, Sandrock I, Ihde S et al. The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute meloid leukemia cells. Leukemia 2009; 23: 1019-1028.
-
(2009)
Leukemia
, vol.23
, pp. 1019-1028
-
-
Flotho, C.1
Claus, R.2
Batz, C.3
Schneider, M.4
Sandrock, I.5
Ihde, S.6
-
4
-
-
84864869497
-
5-Azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU and cell differentiation capacity
-
Curik N, Burda P, Vargova K, Pospisil V, Belickova M, Vlckova P et al. 5-Azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU. and cell differentiation capacity. Leukemia 2012; 26: 1804-1811.
-
(2012)
Leukemia
, vol.26
, pp. 1804-1811
-
-
Curik, N.1
Burda, P.2
Vargova, K.3
Pospisil, V.4
Belickova, M.5
Vlckova, P.6
-
5
-
-
11844264545
-
Induction of gene expression by 5-Aza-2'-deoxycitidine in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) but not epithelial cells by DNAmethylation dependent and-independent mechanisms
-
Schmeltz K, Sattler N, Wagner M, Lü bbert M, Tamm I. Induction of gene expression by 5-Aza-2'-deoxycitidine in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) but not epithelial cells by DNAmethylation dependent and-independent mechanisms. Leukemia 2005; 19: 103-111.
-
(2005)
Leukemia
, vol.19
, pp. 103-111
-
-
Schmeltz, K.1
Sattler, N.2
Wagner, M.3
Lübbert, M.4
Tamm, I.5
-
6
-
-
38149088287
-
Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells
-
Khan R, Schmidt-Mende J, Karimi M, Gogvadze V, Hassan M, Ekström TJ et al. Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells. Exp Hematol 2008; 36: 149-157.
-
(2008)
Exp Hematol
, vol.36
, pp. 149-157
-
-
Khan, R.1
Schmidt-Mende, J.2
Karimi, M.3
Gogvadze, V.4
Hassan, M.5
Ekström, T.J.6
-
7
-
-
74949115148
-
Immunomodulatory effect of 5-azacytidine (5-azaC): Potential role in the transplantation setting
-
Sánchez-Abarca LI, Gutierrez-Cosio S, Santamar?́a C, Caballero-Velazquez T, Blanco B, Herrero-Sánchez C et al. Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. Blood 2010; 115: 107-121.
-
(2010)
Blood
, vol.115
, pp. 107-121
-
-
Sánchez-Abarca Li, G.1
-
8
-
-
77954688477
-
5-azacytidine treatment reorganizes genomic histone modification patterns
-
Komashko VM, Farnham PJ. 5-azacytidine treatment reorganizes genomic histone modification patterns. Epigenetics 2010; 5: 229-240.
-
(2010)
Epigenetics
, vol.5
, pp. 229-240
-
-
Komashko, V.M.1
Farnham, P.J.2
-
9
-
-
70350234722
-
Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines
-
Schaefer M, Hagemann S, Hanna K, Lyko K. Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines. Cancer Res 2009; 69: 8127-8132.
-
(2009)
Cancer Res
, vol.69
, pp. 8127-8132
-
-
Schaefer, M.1
Hagemann, S.2
Hanna, K.3
Lyko, K.4
-
10
-
-
77954581656
-
Maintenance treatment with azacitidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukemia following MDS in complete remission after induction chemotherapy
-
Grö vdal M, Karimi M, Khan R, Aggerholm A, Antunovic P, Astermark J et al. Maintenance treatment with azacitidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukemia following MDS in complete remission after induction chemotherapy. Br J Haematol 2010; 150: 293-302.
-
(2010)
Br J Haematol
, vol.150
, pp. 293-302
-
-
Grövdal, M.K.1
-
11
-
-
33744918070
-
DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia
-
Yang AS, Doshi KD, Choi SW, Mason JB, Mannari RK, Gharybian V et al. DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia. Cancer Res 2006; 66: 5495-5503.
-
(2006)
Cancer Res
, vol.66
, pp. 5495-5503
-
-
Yang, A.S.1
Doshi, K.D.2
Choi, S.W.3
Mason, J.B.4
Mannari, R.K.5
Gharybian, V.6
-
12
-
-
66449125866
-
LINE-1 methylation is plasma DNA as a biomarker of activity of DNA methylation inhibition in patients with solid tumors
-
Aparicio A, North B, Barske L, Wang X, Bollati V, Weisenberger D et al. LINE-1 methylation is plasma DNA as a biomarker of activity of DNA methylation inhibition in patients with solid tumors. Epigenetics 2009; 4: 20-28.
-
(2009)
Epigenetics
, vol.4
, pp. 20-28
-
-
Aparicio, A.1
North, B.2
Barske, L.3
Wang, X.4
Bollati, V.5
Weisenberger, D.6
-
13
-
-
70350720044
-
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
-
Figueroa ME, Skrabanek L, Li Y, Fandy TE, Paietta E, Fernandez H et al. MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood 2009; 114: 3448-3458.
-
(2009)
Blood
, vol.114
, pp. 3448-3458
-
-
Figueroa, M.E.1
Skrabanek, L.2
Li, Y.3
Fandy, T.E.4
Paietta, E.5
Fernandez, H.6
-
14
-
-
84856528270
-
Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer
-
Hon GC, Hawkins RD, Caballero OL, Lo C, Lister R, Pelizzola M et al. Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer. Genome Res 2011; 22: 246-258.
-
(2011)
Genome Res
, vol.22
, pp. 246-258
-
-
Hon, G.C.1
Hawkins, R.D.2
Caballero, O.L.3
Lo, C.4
Lister, R.5
Pelizzola, M.6
-
15
-
-
84893797076
-
Proteomic and genomic profile of high-risk MDS after treatment with 5-azacitidine
-
Romano A, Barresi V, Capizzi C, Giallongo C, Nicolo M, La Cava P et al. Proteomic and genomic profile of high-risk MDS after treatment with 5-azacitidine. ASH annual meeting abstracts Blood 2011; 118: 3818.
-
(2011)
ASH Annual Meeting Abstracts Blood
, vol.118
, pp. 3818
-
-
Romano, A.1
Barresi, V.2
Capizzi, C.3
Giallongo, C.4
Nicolo, M.5
La Cava, P.6
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